Monitoring the quality-of-life in allergic disorders.

abstract：PURPOSE OF REVIEW:Anaphylaxis due to ant sting is increasingly being recognized as a significant problem. Severe allergic reactions to ants are well described in the south-eastern United States, but have only been recognized in recent years as being important in other parts of the world. There are many different ant sp...

journal_title：Current opinion in allergy and clinical immunology

authors： Shek LP,Ngiam NS,Lee BW

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the association between the common dominantly inherited genetic trait hereditary alpha-tryptasemia (HαT) and hymenoptera venom-induced anaphylaxis (HVA). RECENT FINDINGS:Elevated BST has been correlated with more severe systemic anaphylaxis in humans in a number of settings - most notably ...

journal_title：Current opinion in allergy and clinical immunology

authors： O'Connell MP,Lyons JJ

更新日期：2020-10-01 00:00:00

abstract：:Asthma is a disease that is, in large part, defined by abnormalities of pulmonary function. Failure of any new treatment modality to improve objective measures of lung function suggests a limited usefulness of such new therapies. The clear dissociation between inflammation and airways responsiveness indicates the latt...

journal_title：Current opinion in allergy and clinical immunology

authors： Kaminsky DA,Irvin CG

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe recent approaches aimed at improving the treatment of allergic diseases through allergen-specific immunotherapy (SIT). Special emphasis will be given to the approach based on specific targeting of the major histocompatibility complex (MHC) class-II anti...

journal_title：Current opinion in allergy and clinical immunology

authors： Crameri R,Kündig TM,Akdis CA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review is to highlight recent advances in the preparation, documentation and performance of reagents and methods used in the diagnosis of Hymenoptera-venom-induced immediate-type hypersensitivity. RECENT FINDINGS:The following potent allergens have been reported: (1) a low-molec...

journal_title：Current opinion in allergy and clinical immunology

authors： Hamilton RG

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To present and discuss key design concepts for optimizing the impact of observational studies in the field of allergy and to highlight recent findings from NIAID-funded research networks. RECENT FINDINGS:We discuss three concepts. First, the benefit of prospective, longitudinal observational studies ...

journal_title：Current opinion in allergy and clinical immunology

authors： Rudman Spergel AK,Togias A

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The key features of aspirin-exacerbated respiratory diseases (AERDs) include chronic, severe asthma and a high prevalence (60-80%) of chronic rhinosinusitis with nasal polyps, all of which are exacerbated by exposure to aspirin and other NSAIDs. Although the pathogenic mechanisms of AERD are not compl...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi JH,Kim MA,Park HS

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi Y,Lee Y,Park HS

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes how plasma is sourced for fractionation into plasma-derived medicinal products (PDMPs), such as immunoglobulin (Ig) together with differences between plasma from whole blood (recovered plasma) and from plasmapheresis (source plasma) in terms of global plasma supply. Specific area...

journal_title：Current opinion in allergy and clinical immunology

authors： Prevot J,Jolles S

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases have only recently gained serious attention in Africa. This review discusses recent studies that have focused on allergy among Africans and people of African ancestry. RECENT FINDINGS:Time trend studies of the prevalence of allergies in Africa show a consistent increase over a perio...

journal_title：Current opinion in allergy and clinical immunology

authors： Obeng BB,Hartgers F,Boakye D,Yazdanbakhsh M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Children living in US inner cities experience disparate burdens of asthma, especially in severity, impairment, exacerbations, and morbidity. Investigations seeking to better understand the factors and mechanisms underlying asthma prevalence, severity, and exacerbation in children living in these commu...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,Kim H,Searing DA,Zoratti EM,Liu AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite increased clinician awareness, nonadherence to inhaled corticosteroid treatment presents a major challenge to successful asthma management and risks inappropriate treatment escalation, particularly in severe disease. In patients with Type-2 mediated biology, fractional exhaled nitric oxide (Fe...

journal_title：Current opinion in allergy and clinical immunology

authors： Butler CA,Heaney LG

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:During the past decade, easy access to sequence analyses has allowed us to increase our understanding of the pathogenesis of severe combined immunodeficiencies. Here, we describe the expanding clinical and immunological spectrum associated with Omenn syndrome phenotype. In particular, we review the ce...

journal_title：Current opinion in allergy and clinical immunology

authors： Marrella V,Maina V,Villa A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The main feature of allergen-specific immunotherapy is its capacity to modify the natural history of the disease, reducing the development of asthma and new sensitizations after 3-4 years of treatment. For this reason, adherence to the therapy is mandatory, as happens for all chronic medical treatment...

journal_title：Current opinion in allergy and clinical immunology

authors： Senna G,Ridolo E,Calderon M,Lombardi C,Canonica GW,Passalacqua G

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma. RECENT FINDINGS:Gene-expression profiling has allowed simultaneous interrogation of thousands of genes, including the entire ge...

journal_title：Current opinion in allergy and clinical immunology

authors： Platt M,Metson R,Stankovic K

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with asthma require care that is seamlessly coordinated so that asthma symptoms are recognized and managed at home and at school. The purpose of this review is to discuss recent consensus recommendations in school-based asthma care. RECENT FINDINGS:The School-based Asthma Management Program ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kakumanu S,Antos N,Szefler SJ,Lemanske RF Jr

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the syndrome X-linked hypogammaglobulinemia with isolated growth hormone deficiency, focusing on the pedigree described originally. RECENT FINDINGS:An additional case of X-linked hypogammaglobulinemia with isolated growth hormone deficiency and an unaffected male have been bor...

journal_title：Current opinion in allergy and clinical immunology

authors： Stewart DM,Tian L,Notarangelo LD,Nelson DL

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Gene therapy for severe combined immunodeficiency due to adenosine deaminase deficiency has moved from the early trials of safety and feasibility to recent studies demonstrating efficacy and clinical benefit. This review describes the latest advances in gene therapy trials for this condition using per...

journal_title：Current opinion in allergy and clinical immunology

authors： Aiuti A,Ficara F,Cattaneo F,Bordignon C,Roncarolo MG

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of food allergy is increasing. Correct diagnosis is dependent on food challenges, which are not always performed, but more often based on history, skin prick test and specific IgE, leading to possible misdiagnoses. Mucosal provocation tests have been proposed as possible new diagnostic t...

journal_title：Current opinion in allergy and clinical immunology

authors： Kvenshagen BK,Jacobsen M

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The phenomenon of intrinsic or nonatopic asthma continues to raise questions about the possible role of IgE-mediated mechanisms in asthma pathogenesis. With the current availability of anti-IgE therapy for asthma, clarification of this issue has never been more timely and relevant. RECENT FINDINGS:Th...

journal_title：Current opinion in allergy and clinical immunology

authors： Corrigan C

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Cow's milk allergy affects 2-3% of young children, the economic impact of which necessitates search for simple diagnostic tools and affordable milk substitutes. This review examines recent studies on the diagnosis of cow's milk allergy as well as on the allergenicity of milk from other mammalian speci...

journal_title：Current opinion in allergy and clinical immunology

authors： Järvinen KM,Chatchatee P

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe the impact of asthma treatment non-adherence on patients and the healthcare system, and to outline areas of responsibility towards improved adherence. RECENT FINDINGS:The average cost of healthcare expenses for each person in the United States in 2002 was 544...

journal_title：Current opinion in allergy and clinical immunology

authors： Bender BG,Rand C

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Recent studies on the pathogenesis of allergy in both man and experimental animals continue to show the importance of commensal bacteria in the gastrointestinal tract in stimulating and directing the immune system. The interest in modulating commensal bacterial flora with prebiotics and probiotics...

journal_title：Current opinion in allergy and clinical immunology

authors： Savilahti E,Kuitunen M,Vaarala O

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cough is one of the defining symptoms of asthma, wheeze, chest tightness and breathlessness have generally received more attention. The impact of coughing for patients may be more important than currently appreciated and has been rated more troublesome than wheeze, chest tightness or disturba...

journal_title：Current opinion in allergy and clinical immunology

authors： Smith JA

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Although today's cornerstone therapies for asthma (inhaled bronchodilators and corticosteroids) target airway narrowing and lung inflammation, about half of treated asthmatic patients do not achieve good disease control. There is a clear need for new therapeutic approaches and novel drug targets. Rece...

journal_title：Current opinion in allergy and clinical immunology

authors： Grassin-Delyle S,Naline E,Devillier P

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to review recent primary research and developments in the area of probiotics and pediatric atopic disease. RECENT FINDINGS:Research developments in probiotics summarized in this article include the following: (1) the role of probiotics in primary prevention of atopic disea...

journal_title：Current opinion in allergy and clinical immunology

authors： Ogden NS,Bielory L

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The review critically assesses the different phenotypes of angioedemas associated with NSAIDs. Angioedemas exacerbated or induced by NSAIDs have high morbidity and, when they affect the larynx, can lead to death by asphyxiation. RECENT FINDINGS:Angioedema can present as a manifestation of a syndrome ...

journal_title：Current opinion in allergy and clinical immunology

authors： Giavina-Bianchi P,Aun MV,Jares EJ,Kalil J

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Baker's allergy and asthma continue to represent an important contributor of occupational asthma globally. This review identified recent studies related to the prevention of baker's allergy and asthma. RECENT FINDINGS:Studies with respect to regulatory exposure standards, workplace control measures a...

journal_title：Current opinion in allergy and clinical immunology

authors： Jeebhay MF,Baatjies R

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Atopic dermatitis is typified by itchy, inflamed skin. It is increasingly common in the developed world and is a major cause of morbidity in infants and young children. Most children with the disease have high levels of immunoglobulin E and many have concomitant asthma. The cause of the disease is unk...

journal_title：Current opinion in allergy and clinical immunology

authors： Cookson WO,Moffatt MF

更新日期：2002-10-01 00:00:00