Mechanisms of intrinsic asthma.

abstract：PURPOSE OF REVIEW:In this article we consider the characteristics that are associated with chemical respiratory allergens, and that may be essential for effective sensitization of the respiratory tract. RECENT FINDINGS:Chemical respiratory allergens share some characteristics with other chemical allergens, specificall...

journal_title：Current opinion in allergy and clinical immunology

authors： Kimber I,Dearman RJ

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:An inverse relationship between resistance to certain parasitic diseases and measures of atopy and asthma has long been observed. A possible explanation is that genetic determinants which confer protection against detrimental worm burdens are the same determinants involved in atopic asthma. The focus ...

journal_title：Current opinion in allergy and clinical immunology

authors： Barnes KC,Grant AV,Gao P

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Complementary medicines, including acupuncture and Chinese herbal medicine, are being used increasingly for the management of allergies such as allergic rhinitis. Until relatively recently, however, evidence for the efficacy and safety of these therapies in allergic conditions has been lacking. RECEN...

journal_title：Current opinion in allergy and clinical immunology

authors： Xue CC,Li CG,Hügel HM,Story DF

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases have only recently gained serious attention in Africa. This review discusses recent studies that have focused on allergy among Africans and people of African ancestry. RECENT FINDINGS:Time trend studies of the prevalence of allergies in Africa show a consistent increase over a perio...

journal_title：Current opinion in allergy and clinical immunology

authors： Obeng BB,Hartgers F,Boakye D,Yazdanbakhsh M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent application of advanced culture-independent molecular techniques for the identification of microorganisms has contributed to our knowledge on the role of early-life microbial exposure and colonization in health and disease. The purpose of this review is to present the current perspectives regar...

journal_title：Current opinion in allergy and clinical immunology

authors： Beigelman A,Weinstock GM,Bacharier LB

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones. RECENT FINDINGS:Hypersensitivity reactions to quinolones, es...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca-López N,Andreu I,Torres Jaén MJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of food allergy is increasing. Correct diagnosis is dependent on food challenges, which are not always performed, but more often based on history, skin prick test and specific IgE, leading to possible misdiagnoses. Mucosal provocation tests have been proposed as possible new diagnostic t...

journal_title：Current opinion in allergy and clinical immunology

authors： Kvenshagen BK,Jacobsen M

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarize the latest publications on the genetic and environmental determinants of allergic rhinitis. RECENT FINDINGS:Recent advances in genetic technology and bioinformatics have enabled simultaneous unbiased analysis of the entire genome regarding DNA sequence variants, epigeneti...

journal_title：Current opinion in allergy and clinical immunology

authors： Chiarella SE,Fernandez R,Avila PC

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Component-resolved diagnosis (CRD) is an advanced tool capable of aiding the clinician in fine tuning the diagnosis of the causal allergens of a reaction with the added value of providing information of severity risk, potential cross-reactivity, and subsequently, guiding management measures. This revi...

journal_title：Current opinion in allergy and clinical immunology

authors： Cardona V,Ansotegui IJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

journal_title：Current opinion in allergy and clinical immunology

authors： Stoloff SW,Kelly HW

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Defining predisposition to allergic drug reactions has largely focussed on HLA associations, but other genetic and nongenetic factors are also likely to be involved. RECENT FINDINGS:Polymorphic genetic variants in cytokine genes, including IL-10, and co-signalling pathways, including CTLA4, have been...

journal_title：Current opinion in allergy and clinical immunology

authors： Gibson A,Ogese M,Pirmohamed M

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The increasing prevalence of allergic rhinitis, its impact on individual quality of life and social costs, as well as its role as a risk factor for asthma, underline the need for improved treatment options for this disorder. We reviewed the recent literature published in English, dealing with relevant...

journal_title：Current opinion in allergy and clinical immunology

authors： Schultz A,Stuck BA,Feuring M,Hörmann K,Wehling M

更新日期：2003-02-01 00:00:00

abstract：:In the majority of workers with occupational asthma, the disease remains active even several years after removal from exposure or diminution of the levels of exposure to the causal agent. Only 25% or so normalize their lung function and their bronchial responsiveness to nonspecific agents. The aim of this review is to...

journal_title：Current opinion in allergy and clinical immunology

authors： Gautrin D,Lemière C

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the impact of globalization in the management of anaphylaxis and identify potential strategies to improve patients' care and prevention. RECENT FINDINGS:Developments in the field of anaphylaxis have been consistently following these globalization trends offering possibilities of collabo...

journal_title：Current opinion in allergy and clinical immunology

authors： Kase Tanno L,Ansotegui I,Demoly P,Joint Allergy Academies.

更新日期：2018-10-01 00:00:00

abstract：:Fruits are increasingly recognized as a cause of food allergy. The wide cross-reactivity among these foods has been extensively studied. In this review we will focus on studies addressing the clinical relevance of cross-reactivity among fruits, the diagnostic management of patients complaining of reactions to multiple...

journal_title：Current opinion in allergy and clinical immunology

authors： Rodriguez J,Crespo JF

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of allergic disorders has more than doubled in the last two decades leading to increased community concern and anxiety, and unprecedented demand for allergy-specialist services. However, although allergic reactions are common, anaphylaxis is uncommon and fatal anaphylaxis is rare. This ...

journal_title：Current opinion in allergy and clinical immunology

authors： Tang ML,Osborne N,Allen K

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective immediate reactions to NSAIDs imply that patients develop a urticarial/anaphylactic response to a single drug with good tolerance to other compounds. No systematic review of these reactions has yet been made. RECENT FINDINGS:With the increase in consumption of NSAIDs, these have become one ...

journal_title：Current opinion in allergy and clinical immunology

authors： Canto MG,Andreu I,Fernandez J,Blanca M

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent developments on the inter-relationship between food allergy and atopic eczema, with a particular focus on understanding the role of filaggrin gene defects. RECENT FINDINGS:Filaggrin gene defects have recently been identified as a major risk factor for the development of atopic eczema...

journal_title：Current opinion in allergy and clinical immunology

authors： Worth A,Sheikh A

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review we will focus on recent advances in the role of mast cells in the pathophysiology of insect allergy and the possible mechanisms of mast cell activation in anaphylaxis. RECENT FINDINGS:Anaphylactic reactions in the mouse can be induced by several independent pathways involving immunoglo...

journal_title：Current opinion in allergy and clinical immunology

authors： Nauta A,Knippels L,Garssen J,Redegeld F

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Anaphylaxis due to ant sting is increasingly being recognized as a significant problem. Severe allergic reactions to ants are well described in the south-eastern United States, but have only been recognized in recent years as being important in other parts of the world. There are many different ant sp...

journal_title：Current opinion in allergy and clinical immunology

authors： Shek LP,Ngiam NS,Lee BW

更新日期：2004-08-01 00:00:00

abstract：:Asthma is a disease that is, in large part, defined by abnormalities of pulmonary function. Failure of any new treatment modality to improve objective measures of lung function suggests a limited usefulness of such new therapies. The clear dissociation between inflammation and airways responsiveness indicates the latt...

journal_title：Current opinion in allergy and clinical immunology

authors： Kaminsky DA,Irvin CG

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze recent findings on antibiotic hypersensitivity reactions in children focusing on betalactams, with regard to clinical entities, antibiotics involved and diagnostic methods. RECENT FINDINGS:Betalactams are the most frequent cause of antibiotic hypersensitivity, more specifically amoxicillin...

journal_title：Current opinion in allergy and clinical immunology

authors： Fernandez TD,Mayorga C,Ariza A,Corzo JL,Torres MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:New biological agents, in addition to the well-established omalizumab, have been nowadays introduced into clinical practice for severe asthma. This suggested the possibility of an at-home self-administration, as currently happening for other biological agents for immune-mediated diseases. RECENT FIND...

journal_title：Current opinion in allergy and clinical immunology

authors： Lombardi C,Bagnasco D,Passalacqua G

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes how plasma is sourced for fractionation into plasma-derived medicinal products (PDMPs), such as immunoglobulin (Ig) together with differences between plasma from whole blood (recovered plasma) and from plasmapheresis (source plasma) in terms of global plasma supply. Specific area...

journal_title：Current opinion in allergy and clinical immunology

authors： Prevot J,Jolles S

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the concept of food allergy prevention, no successful strategy could be identified until now. Although interventional trials using probiotics, prebiotics, hydrolyzed formula and bacterial lysates early in infancy were found to reduce the incidence of atopic dermatitis, no effect on food sensitizati...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:One strategy to improve asthma control is to identify risk factors for uncontrolled asthma in epidemiologic studies and then consider those risk factors as potential targets for intervention. This article reviews predictors of impairment based on validated tools and predictors of severe asthma exacerb...

journal_title：Current opinion in allergy and clinical immunology

authors： Schatz M

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the association between the common dominantly inherited genetic trait hereditary alpha-tryptasemia (HαT) and hymenoptera venom-induced anaphylaxis (HVA). RECENT FINDINGS:Elevated BST has been correlated with more severe systemic anaphylaxis in humans in a number of settings - most notably ...

journal_title：Current opinion in allergy and clinical immunology

authors： O'Connell MP,Lyons JJ

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Dental professionals and their physicians frequently do not recognize, accurately diagnose or appropriately manage occupational allergies. Dental allergen identification, diagnostics and practical avoidance strategies are summarized in this review. RECENT FINDINGS:Methacrylates, natural rubber latex ...

journal_title：Current opinion in allergy and clinical immunology

authors： Hamann CP,Rodgers PA,Sullivan KM

更新日期：2004-10-01 00:00:00