Clinical features of cross-reactivity of food allergy caused by fruits.

abstract：PURPOSE OF REVIEW:Mastocytosis is a rare disease characterized by increased mast cells in skin and/or internal organs. We evaluate the impact of mastocytosis on diagnosis and treatment of Hymenoptera venom allergy. RECENT FINDINGS:Patients with Hymenoptera venom allergy who suffer from mastocytosis develop life-threat...

journal_title：Current opinion in allergy and clinical immunology

authors： Ruëff F,Placzek M,Przybilla B

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been rediscovered as a public-health problem worldwide. It has been postulated that vitamin D deficiency may explain a portion of the asthma epidemic. The purpose of this review is to present the evidence for a role of vitamin D in asthma. RECENT FINDINGS:Both animal models a...

journal_title：Current opinion in allergy and clinical immunology

authors： Litonjua AA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide an overview on the latest developments in primary immunodeficiency registries worldwide, on the basis of the recent literature amended by some older references to achieve completeness. RECENT FINDINGS:New primary immunodeficiency registries are emerging worldwide, although existing databas...

journal_title：Current opinion in allergy and clinical immunology

authors： Kindle G,Gathmann B,Grimbacher B

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Defining predisposition to allergic drug reactions has largely focussed on HLA associations, but other genetic and nongenetic factors are also likely to be involved. RECENT FINDINGS:Polymorphic genetic variants in cytokine genes, including IL-10, and co-signalling pathways, including CTLA4, have been...

journal_title：Current opinion in allergy and clinical immunology

authors： Gibson A,Ogese M,Pirmohamed M

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Anaphylaxis due to ant sting is increasingly being recognized as a significant problem. Severe allergic reactions to ants are well described in the south-eastern United States, but have only been recognized in recent years as being important in other parts of the world. There are many different ant sp...

journal_title：Current opinion in allergy and clinical immunology

authors： Shek LP,Ngiam NS,Lee BW

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To recognize the relevance of serum tryptase measurement as a useful tool for the diagnosis of allergic diseases and mast cell disorders. RECENT FINDINGS:Recent data on the role of mast cells and tryptase in allergic and other diseases provide new understanding into the mechanisms and causes of anaph...

journal_title：Current opinion in allergy and clinical immunology

authors： Bonadonna P,Scaffidi L,Boni E

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Innate lymphoid type 2 cells (ILC2) have a critical role in the initiation and regulation of type 2 immune responses and are recognized as an important source of type-2 cytokines. Here, we present recent findings of the role of ILC2 in the integration, processing, and coordination of innate and adapti...

journal_title：Current opinion in allergy and clinical immunology

authors： Vreugde S,Wormald PJ

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma features a high degree of heterogeneity in both pathophysiology and therapeutic response, resulting in many asthma patients being treated inadequately. Biomarkers indicative of underlying pathological processes could be used to identify disease subtypes, determine prognosis and to predict or mo...

journal_title：Current opinion in allergy and clinical immunology

authors： Richards LB,Neerincx AH,van Bragt JJMH,Sterk PJ,Bel EHD,Maitland-van der Zee AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing understanding of mechanisms and influencing factors in the development of uncontrolled inflammatory responses in atopy and asthma should serve for the introduction of new preventive measures. This review tries to present the current state of the art and resumes that until now, no really eff...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:During the past decade, easy access to sequence analyses has allowed us to increase our understanding of the pathogenesis of severe combined immunodeficiencies. Here, we describe the expanding clinical and immunological spectrum associated with Omenn syndrome phenotype. In particular, we review the ce...

journal_title：Current opinion in allergy and clinical immunology

authors： Marrella V,Maina V,Villa A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes how plasma is sourced for fractionation into plasma-derived medicinal products (PDMPs), such as immunoglobulin (Ig) together with differences between plasma from whole blood (recovered plasma) and from plasmapheresis (source plasma) in terms of global plasma supply. Specific area...

journal_title：Current opinion in allergy and clinical immunology

authors： Prevot J,Jolles S

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of allergic disorders has more than doubled in the last two decades leading to increased community concern and anxiety, and unprecedented demand for allergy-specialist services. However, although allergic reactions are common, anaphylaxis is uncommon and fatal anaphylaxis is rare. This ...

journal_title：Current opinion in allergy and clinical immunology

authors： Tang ML,Osborne N,Allen K

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review and discuss recent studies on component-resolved diagnostics in food allergy, involving panels of pure allergen molecules or arrays of peptides derived from allergen sequences, and to summarize the reporting of new food allergens during the past 2 years. RECENT ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lidholm J,Ballmer-Weber BK,Mari A,Vieths S

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Biological agents have been a treatment option for many chronic immune-mediated diseases as well as oncological conditions. The issue of infusion reactions is of particular importance and at least in some cases related to the immunogenicity of these drugs with the production of antidrug antibodies. In...

journal_title：Current opinion in allergy and clinical immunology

authors： Matucci A,Nencini F,Pratesi S,Maggi E,Vultaggio A

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:An exposition of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to recommendations. RECENT FINDINGS:In this review, we outline the process whereby the strength of evidence from the literature undergoes a systematic reappraisal. The GRADE system allows four grad...

journal_title：Current opinion in allergy and clinical immunology

authors： Terracciano L,Brozek J,Compalati E,Schünemann H

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarize the latest publications on the genetic and environmental determinants of allergic rhinitis. RECENT FINDINGS:Recent advances in genetic technology and bioinformatics have enabled simultaneous unbiased analysis of the entire genome regarding DNA sequence variants, epigeneti...

journal_title：Current opinion in allergy and clinical immunology

authors： Chiarella SE,Fernandez R,Avila PC

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Eosinophil granulocyte myeloid cells are increased in atopic and nonatopic rhinitis, chronic rhinosinusitis (CRS) and atopic keratoconjunctivitis, diseases of the upper respiratory tract. Eosinophils contain several basic granule proteins, the best known being the eosinophil cationic protein (ECP). EC...

journal_title：Current opinion in allergy and clinical immunology

authors： Bystrom J,Patel SY,Amin K,Bishop-Bailey D

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:One strategy to improve asthma control is to identify risk factors for uncontrolled asthma in epidemiologic studies and then consider those risk factors as potential targets for intervention. This article reviews predictors of impairment based on validated tools and predictors of severe asthma exacerb...

journal_title：Current opinion in allergy and clinical immunology

authors： Schatz M

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular allergy is often encountered by allergists, ophthalmologists, pediatricians, and primary care physicians. An understanding of the immunologic mechanisms, the differential diagnosis, the clinical features, and the treatment of ocular allergy will be useful to all physicians who encounter these p...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedlaender MH

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence suggests that some structural changes caused by mucosal remodeling may be primarily irreversible, which theoretically challenges the current management model of chronic rhinosinusitis (CRS). The relationship between inflammation and remodeling in the mucosa remains complex, yet better underst...

journal_title：Current opinion in allergy and clinical immunology

authors： Bassiouni A,Chen PG,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vernal keratoconjunctivitis (VKC) is a rare chronic self-limiting allergic inflammatory disease of the ocular surface mostly affecting young boys in their first decade of life. In the last few years a new clinical entity of VKC has been described: adult VKC. Two variants have been identified according...

journal_title：Current opinion in allergy and clinical immunology

authors： Di Zazzo A,Bonini S,Fernandes M

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent findings on the skin microbiome. It provides an update on the current understanding of the role of microbiota in healthy skin and in inflammatory and allergic skin diseases. RECENT FINDINGS:Advances in computing and high-throughput sequencing technology have enabled in-dep...

journal_title：Current opinion in allergy and clinical immunology

authors： Zeeuwen PL,Kleerebezem M,Timmerman HM,Schalkwijk J

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite increased clinician awareness, nonadherence to inhaled corticosteroid treatment presents a major challenge to successful asthma management and risks inappropriate treatment escalation, particularly in severe disease. In patients with Type-2 mediated biology, fractional exhaled nitric oxide (Fe...

journal_title：Current opinion in allergy and clinical immunology

authors： Butler CA,Heaney LG

更新日期：2021-02-01 00:00:00

abstract：:Conventional immunotherapy may be associated with the development of adverse reactions, including anaphylaxis, due to the use of increasing doses of allergen. Standardization of extracts is necessary in order to assess the correct amount of allergen administered. In recent years, increased knowledge on the molecular s...

journal_title：Current opinion in allergy and clinical immunology

authors： Pomés A,Chapman MD

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern food animal production is a major contributor to the global economy, owing to advanced intensive indoor production facilities aimed at increasing market readiness and profit. Consequences of these advances are accumulation of dusts, gases, and microbial products that diminish air quality within...

journal_title：Current opinion in allergy and clinical immunology

authors： McClendon CJ,Gerald CL,Waterman JT

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe recent approaches aimed at improving the treatment of allergic diseases through allergen-specific immunotherapy (SIT). Special emphasis will be given to the approach based on specific targeting of the major histocompatibility complex (MHC) class-II anti...

journal_title：Current opinion in allergy and clinical immunology

authors： Crameri R,Kündig TM,Akdis CA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To critically evaluate and summarize studies published between July 2015 and June 2016 linking prenatal exposures and the onset of childhood wheezing illnesses and to discuss future research directions in this field. RECENT FINDINGS:The aggregated evidence indicates a consistent detrimental effect of...

journal_title：Current opinion in allergy and clinical immunology

authors： Rosas-Salazar C,Hartert TV

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze recent findings on antibiotic hypersensitivity reactions in children focusing on betalactams, with regard to clinical entities, antibiotics involved and diagnostic methods. RECENT FINDINGS:Betalactams are the most frequent cause of antibiotic hypersensitivity, more specifically amoxicillin...

journal_title：Current opinion in allergy and clinical immunology

authors： Fernandez TD,Mayorga C,Ariza A,Corzo JL,Torres MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In adults with eosinophilic esophagitis (EoE), a chronic, inflammatory immune-mediated condition of the esophagus, both inflammation and fibrosis are likely associated with symptom generation. Therefore, assessing symptom-based patient-reported outcomes (PROs), defined by US Food and Drug Administrati...

journal_title：Current opinion in allergy and clinical immunology

authors： Safroneeva E,Schoepfer AM

更新日期：2019-04-01 00:00:00