New insights from lung function.

abstract：PURPOSE OF REVIEW:Recent investigation has resulted in significant advances toward definitive therapeutic options for food allergy. In this review, we will explore novel immunotherapeutic interventions for the active treatment of food allergy. RECENT FINDINGS:Because the injection route for allergen immunotherapy to f...

journal_title：Current opinion in allergy and clinical immunology

authors： Scurlock AM,Jones SM

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Many interventions have been undertaken in managing asthma in a population-based framework. The identification of successful interventions would guide policy implementation to improve outcomes in patient morbidity and mortality and healthcare costs. RECENT FINDINGS:Several studies have focussed on em...

journal_title：Current opinion in allergy and clinical immunology

authors： McNairn JD,Ramos C,Portnoy JM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenic mechanisms underlying the correlation between ocular allergy and dry eye disease (DED), highlighting how the first condition may be a risk factor for the second one. RECENT FINDINGS:Recent advances in our comprehension of the pathogenesis of ocular allergy and...

journal_title：Current opinion in allergy and clinical immunology

authors： Villani E,Rabbiolo G,Nucci P

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern food animal production is a major contributor to the global economy, owing to advanced intensive indoor production facilities aimed at increasing market readiness and profit. Consequences of these advances are accumulation of dusts, gases, and microbial products that diminish air quality within...

journal_title：Current opinion in allergy and clinical immunology

authors： McClendon CJ,Gerald CL,Waterman JT

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The review critically assesses the different phenotypes of angioedemas associated with NSAIDs. Angioedemas exacerbated or induced by NSAIDs have high morbidity and, when they affect the larynx, can lead to death by asphyxiation. RECENT FINDINGS:Angioedema can present as a manifestation of a syndrome ...

journal_title：Current opinion in allergy and clinical immunology

authors： Giavina-Bianchi P,Aun MV,Jares EJ,Kalil J

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Contact lens-induced papillary conjunctivitis (CLPC) is a common ocular allergic disease in contact lens wearers. In its more severe form, it can cause giant papillary conjunctivitis, resulting in contact lens intolerance and the need to discontinue the use of contact lenses. This review presents the ...

journal_title：Current opinion in allergy and clinical immunology

authors： Solomon A

更新日期：2016-10-01 00:00:00

abstract：:Conventional immunotherapy may be associated with the development of adverse reactions, including anaphylaxis, due to the use of increasing doses of allergen. Standardization of extracts is necessary in order to assess the correct amount of allergen administered. In recent years, increased knowledge on the molecular s...

journal_title：Current opinion in allergy and clinical immunology

authors： Pomés A,Chapman MD

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review addresses the most recent literature regarding the diagnosis of drug hypersensitivity reactions, which can be classified as immediate or nonimmediate according to the time interval between the last drug administration and the onset. Immediate reactions occur within 1 h; nonimmediate...

journal_title：Current opinion in allergy and clinical immunology

authors： Romano A,Demoly P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article provides an overview of novel nanoscale structures potentially applicable to the field of allergy, and to discuss the required properties, advantages, and disadvantages of those nanostructures for clinical application focusing on diagnosis of drug hypersensitivity reactions. RECENT FINDI...

journal_title：Current opinion in allergy and clinical immunology

authors： Mayorga C,Perez-Inestrosa E,Molina N,Montañez MI

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Children with asthma require care that is seamlessly coordinated so that asthma symptoms are recognized and managed at home and at school. The purpose of this review is to discuss recent consensus recommendations in school-based asthma care. RECENT FINDINGS:The School-based Asthma Management Program ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kakumanu S,Antos N,Szefler SJ,Lemanske RF Jr

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The phenomenon of intrinsic or nonatopic asthma continues to raise questions about the possible role of IgE-mediated mechanisms in asthma pathogenesis. With the current availability of anti-IgE therapy for asthma, clarification of this issue has never been more timely and relevant. RECENT FINDINGS:Th...

journal_title：Current opinion in allergy and clinical immunology

authors： Corrigan C

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Component-resolved diagnosis (CRD) is an advanced tool capable of aiding the clinician in fine tuning the diagnosis of the causal allergens of a reaction with the added value of providing information of severity risk, potential cross-reactivity, and subsequently, guiding management measures. This revi...

journal_title：Current opinion in allergy and clinical immunology

authors： Cardona V,Ansotegui IJ

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:One strategy to improve asthma control is to identify risk factors for uncontrolled asthma in epidemiologic studies and then consider those risk factors as potential targets for intervention. This article reviews predictors of impairment based on validated tools and predictors of severe asthma exacerb...

journal_title：Current opinion in allergy and clinical immunology

authors： Schatz M

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Dry eye disease (DED) is a complex, multifactorial condition that is challenging to diagnose and monitor clinically. To date, diagnosis has consisted largely of self-reported symptom questionnaires and a collection of clinical tests including vital dye staining, estimation of tear breakup time and Sch...

journal_title：Current opinion in allergy and clinical immunology

authors： Dohlman TH,Ciralsky JB,Lai EC

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. RECENT FINDINGS:Studies on mice have revealed that apart from haemangi...

journal_title：Current opinion in allergy and clinical immunology

authors： Regenfuss B,Bock F,Cursiefen C

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is prevalent in inner-city populations, exhibiting significant morbidity and mortality. This review focuses on the consequential findings of recent literature, providing insight into onset of asthma, complicating factors, prediction of exacerbations, and novel treatment strategies. RECENT FIND...

journal_title：Current opinion in allergy and clinical immunology

authors： Dutmer CM,McGraw MD,Liu AH

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypersensitivity pneumonitis is a group of immunologically mediated diseases caused by an abnormal response to a wide variety of inhaled antigens. Its pathogenesis is complex and involves many immunological concepts. This review discusses recent advances in our understanding of the pathogenesis of hyp...

journal_title：Current opinion in allergy and clinical immunology

authors： Girard M,Israël-Assayag E,Cormier Y

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review we will focus on recent advances in the role of mast cells in the pathophysiology of insect allergy and the possible mechanisms of mast cell activation in anaphylaxis. RECENT FINDINGS:Anaphylactic reactions in the mouse can be induced by several independent pathways involving immunoglo...

journal_title：Current opinion in allergy and clinical immunology

authors： Nauta A,Knippels L,Garssen J,Redegeld F

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Defining predisposition to allergic drug reactions has largely focussed on HLA associations, but other genetic and nongenetic factors are also likely to be involved. RECENT FINDINGS:Polymorphic genetic variants in cytokine genes, including IL-10, and co-signalling pathways, including CTLA4, have been...

journal_title：Current opinion in allergy and clinical immunology

authors： Gibson A,Ogese M,Pirmohamed M

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The review intends to clarify understanding of when and how skin patch tests can be used to help drug allergy diagnosis and identify causally relevant drugs. It aims to give an understanding of which clinical patterns of drug reaction are produced by T-lymphocyte-mediated pathomechanisms since these a...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedmann PS,Ardern-Jones M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular allergic contact dermatitis is a common yet challenging and frequently misdiagnosed condition. Inappropriate or delayed treatment can contribute to a variety of clinical symptoms such as tearing and itching with signs such as ptosis and cicatricial ectropion, resulting in deterioration of disea...

journal_title：Current opinion in allergy and clinical immunology

authors： Erdinest N,Nche E,London N,Solomon A

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Vernal keratoconjunctivitis (VKC) is a rare chronic self-limiting allergic inflammatory disease of the ocular surface mostly affecting young boys in their first decade of life. In the last few years a new clinical entity of VKC has been described: adult VKC. Two variants have been identified according...

journal_title：Current opinion in allergy and clinical immunology

authors： Di Zazzo A,Bonini S,Fernandes M

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Although today's cornerstone therapies for asthma (inhaled bronchodilators and corticosteroids) target airway narrowing and lung inflammation, about half of treated asthmatic patients do not achieve good disease control. There is a clear need for new therapeutic approaches and novel drug targets. Rece...

journal_title：Current opinion in allergy and clinical immunology

authors： Grassin-Delyle S,Naline E,Devillier P

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review and discuss recent studies on component-resolved diagnostics in food allergy, involving panels of pure allergen molecules or arrays of peptides derived from allergen sequences, and to summarize the reporting of new food allergens during the past 2 years. RECENT ...

journal_title：Current opinion in allergy and clinical immunology

authors： Lidholm J,Ballmer-Weber BK,Mari A,Vieths S

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma is the most common, potentially serious medical problem to complicate pregnancy. Women with asthma have been shown to be at increased risk of complications during pregnancy. Managing asthma during pregnancy is unique because the effect of both the illness and the treatment on the developing fet...

journal_title：Current opinion in allergy and clinical immunology

authors： Namazy JA,Schatz M

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Eosinophil granulocyte myeloid cells are increased in atopic and nonatopic rhinitis, chronic rhinosinusitis (CRS) and atopic keratoconjunctivitis, diseases of the upper respiratory tract. Eosinophils contain several basic granule proteins, the best known being the eosinophil cationic protein (ECP). EC...

journal_title：Current opinion in allergy and clinical immunology

authors： Bystrom J,Patel SY,Amin K,Bishop-Bailey D

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence for adverse respiratory effects of occupational exposure to disinfectants and cleaning products (DCPs) has grown in the last two decades. The relationship between DCPs and asthma is well documented but questions remain regarding specific causal agents. Beyond asthma, associations between DCPs...

journal_title：Current opinion in allergy and clinical immunology

authors： Dumas O

更新日期：2020-12-05 00:00:00

abstract：PURPOSE OF REVIEW:Biological agents have been a treatment option for many chronic immune-mediated diseases as well as oncological conditions. The issue of infusion reactions is of particular importance and at least in some cases related to the immunogenicity of these drugs with the production of antidrug antibodies. In...

journal_title：Current opinion in allergy and clinical immunology

authors： Matucci A,Nencini F,Pratesi S,Maggi E,Vultaggio A

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones. RECENT FINDINGS:Hypersensitivity reactions to quinolones, es...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca-López N,Andreu I,Torres Jaén MJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite increased clinician awareness, nonadherence to inhaled corticosteroid treatment presents a major challenge to successful asthma management and risks inappropriate treatment escalation, particularly in severe disease. In patients with Type-2 mediated biology, fractional exhaled nitric oxide (Fe...

journal_title：Current opinion in allergy and clinical immunology

authors： Butler CA,Heaney LG

更新日期：2021-02-01 00:00:00