Advances in ocular allergy: basic mechanisms, clinical patterns and new therapies.

abstract：PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi Y,Lee Y,Park HS

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review addresses the most recent literature regarding the diagnosis of drug hypersensitivity reactions, which can be classified as immediate or nonimmediate according to the time interval between the last drug administration and the onset. Immediate reactions occur within 1 h; nonimmediate...

journal_title：Current opinion in allergy and clinical immunology

authors： Romano A,Demoly P

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Due to the continuously changing environmental conditions, it is necessary to regularly monitor and update the spectrum of contact allergens that elicit contact dermatitis. New contact allergens and known contact allergens with currently increasing importance need to be identified for diagnostic and p...

journal_title：Current opinion in allergy and clinical immunology

authors： Brasch J

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic rhinitis due its high prevalence and burden needs to be properly treated. The disease's clinical features impose well tolerated drugs usable for long-term treatment. Nowadays, second-generation antihistamines and inhaled steroids represent the milestone of rhinitis therapy. The aim of the pre...

journal_title：Current opinion in allergy and clinical immunology

authors： Braido F,Arcadipane F,Marugo F,Hayashi M,Pawankar R

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic conjunctivitis is common and may be the most prominent or the only feature of allergies. Immunotherapy has been used as a primary treatment for allergies since the early 1900s. Currently the use of immunotherapy for allergic rhinoconjunctivitis is well established and has been shown to decrea...

journal_title：Current opinion in allergy and clinical immunology

authors： Bielory L,Mongia A

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones. RECENT FINDINGS:Hypersensitivity reactions to quinolones, es...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca-López N,Andreu I,Torres Jaén MJ

更新日期：2011-08-01 00:00:00

abstract：:Allergic diseases such as atopic dermatitis, rhinitis and asthma are thought to result from a dysregulated immune response to commonly encountered antigens in genetically predisposed individuals. This response leads to chronic eosinophil-rich allergic inflammation and is controlled by Th2 lymphocytes. The first step i...

journal_title：Current opinion in allergy and clinical immunology

authors： Lambrecht BN

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze recent findings on antibiotic hypersensitivity reactions in children focusing on betalactams, with regard to clinical entities, antibiotics involved and diagnostic methods. RECENT FINDINGS:Betalactams are the most frequent cause of antibiotic hypersensitivity, more specifically amoxicillin...

journal_title：Current opinion in allergy and clinical immunology

authors： Fernandez TD,Mayorga C,Ariza A,Corzo JL,Torres MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma features a high degree of heterogeneity in both pathophysiology and therapeutic response, resulting in many asthma patients being treated inadequately. Biomarkers indicative of underlying pathological processes could be used to identify disease subtypes, determine prognosis and to predict or mo...

journal_title：Current opinion in allergy and clinical immunology

authors： Richards LB,Neerincx AH,van Bragt JJMH,Sterk PJ,Bel EHD,Maitland-van der Zee AH

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Indoor pollutants and allergens cause asthma symptoms and exacerbations and influence the risk of developing asthma. We review recent studies regarding the effects of the indoor environment on childhood asthma. RECENT FINDINGS:Exposure to some indoor allergens and second hand smoke are causally relat...

journal_title：Current opinion in allergy and clinical immunology

authors： Ahluwalia SK,Matsui EC

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarize the latest publications on the genetic and environmental determinants of allergic rhinitis. RECENT FINDINGS:Recent advances in genetic technology and bioinformatics have enabled simultaneous unbiased analysis of the entire genome regarding DNA sequence variants, epigeneti...

journal_title：Current opinion in allergy and clinical immunology

authors： Chiarella SE,Fernandez R,Avila PC

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence suggests that some structural changes caused by mucosal remodeling may be primarily irreversible, which theoretically challenges the current management model of chronic rhinosinusitis (CRS). The relationship between inflammation and remodeling in the mucosa remains complex, yet better underst...

journal_title：Current opinion in allergy and clinical immunology

authors： Bassiouni A,Chen PG,Wormald PJ

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:In the US anterior ocular inflammatory disease (AOID) composed of the spectrum of ocular allergies, different forms of infectious conjunctivitis, and dry eye diseases, affects over 40% of the population. This review evaluates the current economic costs for AOID associated pharmacotherapies. RECENT FI...

journal_title：Current opinion in allergy and clinical immunology

authors： Khan RS,Rizvi S,Syed BA,Bielory L

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma and rhinitis are commonly associated and they influence their respective control. New observations have contributed to better understand how to assess those conditions and how they influence each other. RECENT FINDINGS:Recent studies found that not only the intensity, but also the duration of ...

journal_title：Current opinion in allergy and clinical immunology

authors： Boulay ME,Morin A,Laprise C,Boulet LP

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Personalized medicine encompasses the use of biological information such as genomics to provide tailored interventions for patients. The review explores the ethical, legal, and social issues that have emerged with personalized medicine and must be considered because of the complex nature of providing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Joly Y,Saulnier KM,Osien G,Knoppers BM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only commercially available materials, be well tolerated and easy to perform in both the inpatient and ou...

journal_title：Current opinion in allergy and clinical immunology

authors： Macy E

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective immediate reactions to NSAIDs imply that patients develop a urticarial/anaphylactic response to a single drug with good tolerance to other compounds. No systematic review of these reactions has yet been made. RECENT FINDINGS:With the increase in consumption of NSAIDs, these have become one ...

journal_title：Current opinion in allergy and clinical immunology

authors： Canto MG,Andreu I,Fernandez J,Blanca M

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In 2000, inhalation of butter flavoring vapors was first associated with clinical bronchiolitis obliterans among workers in microwave popcorn production. Toxicologic and epidemiologic studies in the succeeding 5 years have intervention and research implications. RECENT FINDINGS:Irreversible obstructi...

journal_title：Current opinion in allergy and clinical immunology

authors： Kreiss K

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Patient and physician perspectives on the impact of allergic rhinitis have previously been studied in the general population. We evaluated the burden of allergic rhinitis among patients from the members of European allergy patient organizations. The Patient Voice Allergy Survey was a quantitative, sel...

journal_title：Current opinion in allergy and clinical immunology

authors： Valovirta E,Myrseth SE,Palkonen S

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The review intends to clarify understanding of when and how skin patch tests can be used to help drug allergy diagnosis and identify causally relevant drugs. It aims to give an understanding of which clinical patterns of drug reaction are produced by T-lymphocyte-mediated pathomechanisms since these a...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedmann PS,Ardern-Jones M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this article is to evaluate developments in the knowledge of suppressor of cytokine signaling (SOCS) protein ocular allergy and the potential of SOCS proteins as targets for therapeutic strategies. RECENT FINDINGS:The family of proteins designated SOCS proteins plays an important role in ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kubo M,Ozaki A,Tanaka S,Okamoto M,Fukushima A

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Exhaled nitric oxide has been proposed as a useful noninvasive marker of airway inflammation in asthma. Great efforts have been made to standardize the methodology for exhaled nitric oxide measurement in both children and adults. As a consequence there is now an opportunity to establish the precise re...

journal_title：Current opinion in allergy and clinical immunology

authors： Payne DN

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Biological hypersensitivity to environmental stimuli is a fundamental feature of atopy predisposing to a number of clinically expressed disorders including allergic rhinitis, atopic dermatitis or eczema, and allergic asthma. There is provocative evidence that psychological stress constitutes an increa...

journal_title：Current opinion in allergy and clinical immunology

authors： Wright RJ,Cohen RT,Cohen S

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases represent a growing global health concern, especially among pediatric populations. Current strategies for the treatment of allergies and asthma focus on limiting the severity of the symptoms; however, additional research investigating the mechanisms promoting inflammation in the cont...

journal_title：Current opinion in allergy and clinical immunology

authors： Inclan-Rico JM,Ponessa JJ,Siracusa MC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyse the most recently published studies on the prevalence of allergic conjunctivitis alone or in association with allergic rhinitis, and the clinical and demographic aspects of the disease. RECENT FINDINGS:Allergic conjunctivitis or conjunctival symptoms are present in 30-71% of patients with ...

journal_title：Current opinion in allergy and clinical immunology

authors： Leonardi A,Castegnaro A,Valerio AL,Lazzarini D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Irreversible airflow limitation develops in some patients with asthma and is related to poorer prognosis. This paper reviews recent literature on natural course, risk factors, and potential mechanisms of persistent airflow limitation in asthma. RECENT FINDINGS:The natural course of persistent airflow...

journal_title：Current opinion in allergy and clinical immunology

authors： ten Brinke A

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:During the past decade, easy access to sequence analyses has allowed us to increase our understanding of the pathogenesis of severe combined immunodeficiencies. Here, we describe the expanding clinical and immunological spectrum associated with Omenn syndrome phenotype. In particular, we review the ce...

journal_title：Current opinion in allergy and clinical immunology

authors： Marrella V,Maina V,Villa A

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Dry eye disease (DED) is a complex, multifactorial condition that is challenging to diagnose and monitor clinically. To date, diagnosis has consisted largely of self-reported symptom questionnaires and a collection of clinical tests including vital dye staining, estimation of tear breakup time and Sch...

journal_title：Current opinion in allergy and clinical immunology

authors： Dohlman TH,Ciralsky JB,Lai EC

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight recent advances in gene-expression profiling of nasal polyps in patients with chronic rhinosinusitis and aspirin-sensitive asthma. RECENT FINDINGS:Gene-expression profiling has allowed simultaneous interrogation of thousands of genes, including the entire ge...

journal_title：Current opinion in allergy and clinical immunology

authors： Platt M,Metson R,Stankovic K

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The increasing prevalence of allergic rhinitis, its impact on individual quality of life and social costs, as well as its role as a risk factor for asthma, underline the need for improved treatment options for this disorder. We reviewed the recent literature published in English, dealing with relevant...

journal_title：Current opinion in allergy and clinical immunology

authors： Schultz A,Stuck BA,Feuring M,Hörmann K,Wehling M

更新日期：2003-02-01 00:00:00