Asthma and rhinitis: what is the relationship?

abstract：PURPOSE OF REVIEW:Allergen-specific immunotherapy is the only curative treatment for allergic diseases. In spite of the great progress in both vaccine development and the methods of allergen immunotherapy (AIT) in recent years, several key problems related to limited efficacy, side-effects, low patient adherence and th...

journal_title：Current opinion in allergy and clinical immunology

authors： Jutel M,Akdis CA

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases have only recently gained serious attention in Africa. This review discusses recent studies that have focused on allergy among Africans and people of African ancestry. RECENT FINDINGS:Time trend studies of the prevalence of allergies in Africa show a consistent increase over a perio...

journal_title：Current opinion in allergy and clinical immunology

authors： Obeng BB,Hartgers F,Boakye D,Yazdanbakhsh M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The increasing prevalence of allergic rhinitis, its impact on individual quality of life and social costs, as well as its role as a risk factor for asthma, underline the need for improved treatment options for this disorder. We reviewed the recent literature published in English, dealing with relevant...

journal_title：Current opinion in allergy and clinical immunology

authors： Schultz A,Stuck BA,Feuring M,Hörmann K,Wehling M

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will cover advances over the past year in defining airway endotypes in asthma by gene expression and the relationship between these endotypes and clinical traits. RECENT FINDINGS:Expression profiling studies of asthmatic airway samples continue to reveal significant heterogeneity in airwa...

journal_title：Current opinion in allergy and clinical immunology

authors： Wesolowska-Andersen A,Seibold MA

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarize the latest publications on the genetic and environmental determinants of allergic rhinitis. RECENT FINDINGS:Recent advances in genetic technology and bioinformatics have enabled simultaneous unbiased analysis of the entire genome regarding DNA sequence variants, epigeneti...

journal_title：Current opinion in allergy and clinical immunology

authors： Chiarella SE,Fernandez R,Avila PC

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Although today's cornerstone therapies for asthma (inhaled bronchodilators and corticosteroids) target airway narrowing and lung inflammation, about half of treated asthmatic patients do not achieve good disease control. There is a clear need for new therapeutic approaches and novel drug targets. Rece...

journal_title：Current opinion in allergy and clinical immunology

authors： Grassin-Delyle S,Naline E,Devillier P

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Biological hypersensitivity to environmental stimuli is a fundamental feature of atopy predisposing to a number of clinically expressed disorders including allergic rhinitis, atopic dermatitis or eczema, and allergic asthma. There is provocative evidence that psychological stress constitutes an increa...

journal_title：Current opinion in allergy and clinical immunology

authors： Wright RJ,Cohen RT,Cohen S

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To present an update on the recent advances in the understanding of the mechanisms and practical management of oral mite anaphylaxis (OMA, pancake syndrome). RECENT FINDINGS:Among novel observations regarding OMA, this review highlights the increased prevalence of aspirin/NSAID hypersensitivity inpat...

journal_title：Current opinion in allergy and clinical immunology

authors： Sánchez-Borges M,Capriles-Hulett A,Fernandez-Caldas E

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The key features of aspirin-exacerbated respiratory diseases (AERDs) include chronic, severe asthma and a high prevalence (60-80%) of chronic rhinosinusitis with nasal polyps, all of which are exacerbated by exposure to aspirin and other NSAIDs. Although the pathogenic mechanisms of AERD are not compl...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi JH,Kim MA,Park HS

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Knowledge of the epidemiology, natural history and risk factors of insect-venom allergy is crucial for improving the clinical management of allergic patients. This review focuses on the recent research on these aspects of Hymenoptera-sting anaphylactic reactions. RECENT FINDINGS:The latest data from ...

journal_title：Current opinion in allergy and clinical immunology

authors： Bilò BM,Bonifazi F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Personalized medicine encompasses the use of biological information such as genomics to provide tailored interventions for patients. The review explores the ethical, legal, and social issues that have emerged with personalized medicine and must be considered because of the complex nature of providing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Joly Y,Saulnier KM,Osien G,Knoppers BM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:An exposition of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to recommendations. RECENT FINDINGS:In this review, we outline the process whereby the strength of evidence from the literature undergoes a systematic reappraisal. The GRADE system allows four grad...

journal_title：Current opinion in allergy and clinical immunology

authors： Terracciano L,Brozek J,Compalati E,Schünemann H

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyse the available data in the field of immediate allergic reactions to beta-lactams, with particular emphasis on more recent studies, and to comment on the future role of this group of antibiotics. RECENT FINDINGS:The world of beta-lactams has become more complex than initially thought, due to...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca M,Torres MJ,Mayorga C,Perez-Inestrosa E,Suau R,Montañez MI,Juarez C

更新日期：2004-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to describe the role of precision medicine in the diagnosis, treatment, and monitoring of cow's milk allergy. RECENT FINDINGS:The development of 'omics' sciences in the field of food allergy has led to a better understanding of the allergenicity of cow's milk proteins and si...

journal_title：Current opinion in allergy and clinical immunology

authors： D'Auria E,Venter C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace. RECENT FINDINGS:Increased recruitment and infiltration of ne...

journal_title：Current opinion in allergy and clinical immunology

authors： Choi Y,Lee Y,Park HS

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The main feature of allergen-specific immunotherapy is its capacity to modify the natural history of the disease, reducing the development of asthma and new sensitizations after 3-4 years of treatment. For this reason, adherence to the therapy is mandatory, as happens for all chronic medical treatment...

journal_title：Current opinion in allergy and clinical immunology

authors： Senna G,Ridolo E,Calderon M,Lombardi C,Canonica GW,Passalacqua G

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Baker's allergy and asthma continue to represent an important contributor of occupational asthma globally. This review identified recent studies related to the prevention of baker's allergy and asthma. RECENT FINDINGS:Studies with respect to regulatory exposure standards, workplace control measures a...

journal_title：Current opinion in allergy and clinical immunology

authors： Jeebhay MF,Baatjies R

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern food animal production is a major contributor to the global economy, owing to advanced intensive indoor production facilities aimed at increasing market readiness and profit. Consequences of these advances are accumulation of dusts, gases, and microbial products that diminish air quality within...

journal_title：Current opinion in allergy and clinical immunology

authors： McClendon CJ,Gerald CL,Waterman JT

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Recent studies on the pathogenesis of allergy in both man and experimental animals continue to show the importance of commensal bacteria in the gastrointestinal tract in stimulating and directing the immune system. The interest in modulating commensal bacterial flora with prebiotics and probiotics...

journal_title：Current opinion in allergy and clinical immunology

authors： Savilahti E,Kuitunen M,Vaarala O

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the theoretical background and current evidence regarding parent-initiated oral corticosteroid (PIOCS) therapy in preschool wheeze and asthma in school-aged children. RECENT FINDINGS:In school-aged children with asthma PIOCS, given during acute episodes, has been associated with a modest re...

journal_title：Current opinion in allergy and clinical immunology

authors： Vuillermin PJ,Robertson CF,South M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of food allergy is increasing. Correct diagnosis is dependent on food challenges, which are not always performed, but more often based on history, skin prick test and specific IgE, leading to possible misdiagnoses. Mucosal provocation tests have been proposed as possible new diagnostic t...

journal_title：Current opinion in allergy and clinical immunology

authors： Kvenshagen BK,Jacobsen M

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of allergic disorders has more than doubled in the last two decades leading to increased community concern and anxiety, and unprecedented demand for allergy-specialist services. However, although allergic reactions are common, anaphylaxis is uncommon and fatal anaphylaxis is rare. This ...

journal_title：Current opinion in allergy and clinical immunology

authors： Tang ML,Osborne N,Allen K

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The review critically assesses the different phenotypes of angioedemas associated with NSAIDs. Angioedemas exacerbated or induced by NSAIDs have high morbidity and, when they affect the larynx, can lead to death by asphyxiation. RECENT FINDINGS:Angioedema can present as a manifestation of a syndrome ...

journal_title：Current opinion in allergy and clinical immunology

authors： Giavina-Bianchi P,Aun MV,Jares EJ,Kalil J

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The review intends to clarify understanding of when and how skin patch tests can be used to help drug allergy diagnosis and identify causally relevant drugs. It aims to give an understanding of which clinical patterns of drug reaction are produced by T-lymphocyte-mediated pathomechanisms since these a...

journal_title：Current opinion in allergy and clinical immunology

authors： Friedmann PS,Ardern-Jones M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to examine in detail the new advances in the pathomechanisms and diagnosis of immediate and nonimmediate hypersensitivity reactions to quinolones, as well as analyze cross-reactivity among different quinolones. RECENT FINDINGS:Hypersensitivity reactions to quinolones, es...

journal_title：Current opinion in allergy and clinical immunology

authors： Blanca-López N,Andreu I,Torres Jaén MJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyse the most recently published studies on the prevalence of allergic conjunctivitis alone or in association with allergic rhinitis, and the clinical and demographic aspects of the disease. RECENT FINDINGS:Allergic conjunctivitis or conjunctival symptoms are present in 30-71% of patients with ...

journal_title：Current opinion in allergy and clinical immunology

authors： Leonardi A,Castegnaro A,Valerio AL,Lazzarini D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The aim of this review is to highlight the prevalence of allergic rhinitis in athletes and the impact this condition may have on their athletic performance. Furthermore, the optimal management of medical conditions in the elite athlete forms an important part of protecting the health of the athlete. RECENT FIN...

journal_title：Current opinion in allergy and clinical immunology

authors： Dijkstra HP,Robson-Ansley P

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Targeting allergens to surface receptors on antigen presenting cells may provide a therapeutic strategy for allergic disease. This article discusses the immunomodulatory capacity of a molecule (H22-Fel d 1), which targets the major cat allergen, Fel d 1, to the high affinity IgG receptor, Fc gammaRI, ...

journal_title：Current opinion in allergy and clinical immunology

authors： Hulse KE,Woodfolk JA

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Mastocytosis is a rare disease characterized by increased mast cells in skin and/or internal organs. We evaluate the impact of mastocytosis on diagnosis and treatment of Hymenoptera venom allergy. RECENT FINDINGS:Patients with Hymenoptera venom allergy who suffer from mastocytosis develop life-threat...

journal_title：Current opinion in allergy and clinical immunology

authors： Ruëff F,Placzek M,Przybilla B

更新日期：2006-08-01 00:00:00

abstract：:Allergic diseases such as atopic dermatitis, rhinitis and asthma are thought to result from a dysregulated immune response to commonly encountered antigens in genetically predisposed individuals. This response leads to chronic eosinophil-rich allergic inflammation and is controlled by Th2 lymphocytes. The first step i...

journal_title：Current opinion in allergy and clinical immunology

authors： Lambrecht BN

更新日期：2001-02-01 00:00:00