[Medico-legal assessment of systemic sclerosis].

abstract：:Sjögren's syndrome is a systemic inflammatory rheumatic disorder of unknown origin with so far inadequate therapy options. Management of Sjögren's syndrome is still primarily palliative using local symptomatic measures, and if appropriate glucocorticoids, NSAIDs and immunosuppressive drugs. New clues to the pathogenes...

journal_title：Zeitschrift fur Rheumatologie

authors： Feist E,Dörner T,Hansen A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis is found in approximately 2 % of the total population in Europe and the peak incidence of the disease is during the fourth and fifth decades of life. In approximately 15 % the first symptoms of the disease occur at the level of the foot and ankle. If the early stage-dependent therapy wit...

journal_title：Zeitschrift fur Rheumatologie

authors： Thomas M,Jordan M

更新日期：2014-11-01 00:00:00

abstract：:Transmitting a substantial amount of basic knowledge in Rheumatology to all medical students is essential for the future medical care of patients with rheumatic diseases for two reasons: on the one hand, future general practitioners will need to master the patterns of rheumatic diseases to recognize them fast enough i...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Baerwald C,Bergner R,Feuchtenberger M,Gebhardt C,Hagen M,Keyßer G,Lorenz HM,Witte T

更新日期：2020-12-02 00:00:00

abstract：:Three new findings are reviewed that help to understand the mechanisms of action of anti-rheumatic gold drugs, such as disodium aurothiomalate (Na2Au(I)TM): i) We found that Na2Au(I)TM selectively inhibits T-cell receptor-mediated antigen recognition by murine CD4+ T-cell hybridomas specific for antigenic peptides con...

journal_title：Zeitschrift fur Rheumatologie

authors： Griem P,Gleichmann E

更新日期：1996-09-01 00:00:00

abstract：:Rehabilitation activities belong to tertiary prevention. The latter includes all measures that aim at avoiding the progression of a physical disability to a handicap, or those that diminish the extent of the handicap. Complex rehabilitation programs represent a cooperation of medical, occupational, and social reintegr...

journal_title：Zeitschrift fur Rheumatologie

authors： Wessel G,Leistner K

更新日期：1990-09-01 00:00:00

abstract：:A 74-year-old female patient with rheumatoid arthritis was diagnosed with Pneumocystis jiroveci pneumonia (PcP) following therapy with methotrexate and prednisone. Although bactrim treatment was initiated and PcP was not detected by a control bronchoalveolar lavage, the patient died. The precise cause of death remains...

journal_title：Zeitschrift fur Rheumatologie

authors： Bertisch B,Ruef C

更新日期：2006-02-01 00:00:00

abstract：:Autoreactivity plays a major role in the pathogenesis of RA. The rheumatoid factor has been and still is for now more than 50 years the only autoreactivity that is clinically applied in the diagnosis of RA. This well reflects the current way of thinking that a single antigen or a single cause drives an individual into...

journal_title：Zeitschrift fur Rheumatologie

authors： Bläss S,Engel JM,Burmester GR

更新日期：2001-02-01 00:00:00

abstract：:When patents expire, usually after 10 years in Germany, generic medicines routinely enter the market in place of conventional medications leading to significant reductions in prices. Currently the first biologicals are approaching patent expiry. Because of the biochemical complexities truly identical imitators are unr...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Dörner T

更新日期：2013-11-01 00:00:00

abstract：:Wegener's granulomatosis, Churg-Strauss syndrome and analgesics intolerance syndrome with polyps demonstrate non-specific manifestations in the head and neck region. These symptoms can often lead to early diagnosis and initiation of the correct therapy. However, symptoms are often ambiguous and many rare differential ...

journal_title：Zeitschrift fur Rheumatologie

authors： Laudien M,Ambrosch P,Till A,Podschun R,Lamprecht P

更新日期：2008-09-01 00:00:00

abstract：:The effect of meloxicam, a new non-steroidal anti-inflammatory drug, on spontaneous osteoarthrosis of the ankle joint in Crl: CDBR rats was investigated. The drug was administered in the feed at doses of 0.4, 0.6 and 0.8 mg/kg/day over a period of 2 years to 50 males and 50 females per dose. 100 male rats and 100 fema...

journal_title：Zeitschrift fur Rheumatologie

authors： Mohr W,Lehmann H,Engelhardt G

更新日期：1997-01-01 00:00:00

abstract：:Heberden nodes affect mainly middle-aged women. Inheritance is autosomal dominant in female and autosomal recessive in male patients. We report the case of a young man who presented already with 12 years of age with pain in the distal finger joints. There were no other clinical or serological signs for other rheumatoi...

journal_title：Zeitschrift fur Rheumatologie

authors： Rascu A,Kraetsch HG,Grünke M,Kalden JR,Manger B

更新日期：1999-04-01 00:00:00

abstract：:Childhood onset rheumatic and musculoskeletal diseases often continue into adulthood. These diseases are associated with a high risk of permanent disability and impairment in the quality of life of people affected. Adolescence and young adulthood represent a particular risk phase for an unfavorable long-term outcome. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Minden K,Schalm S

更新日期：2016-08-01 00:00:00

abstract：:MicroRNAs are small non-coding RNAs which are crucial for the fine regulation of gene expression. Recent results suggest that these molecules display multifaceted functions in B-cells and T-cells in rheumatic inflammatory diseases. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Wittmann J,Jäck HM,Mashreghi MF

更新日期：2011-08-01 00:00:00

abstract：:NSAIDs, including acetylsalicylic acid, are frequently classified as peripherally-acting analgesics. This is based on the fact that these substances, among other effects, inhibit the biosynthesis of prostaglandines. A few solid arguments, however, stand against an exclusively peripheral mode of the analgesic action of...

journal_title：Zeitschrift fur Rheumatologie

authors： Jurna I

更新日期：1991-01-01 00:00:00

abstract：:The data from a combined pathological and kinesiological investigation in autopsy specimens of the cervical spine were used to test whether adjacent motion segments compensate for loss of mobility at a given level. In the segments adjacent to a low-mobile one no evidence was found of compensatory hypermobility, of an ...

journal_title：Zeitschrift fur Rheumatologie

authors： Eulderink F,ten Have HA

更新日期：1982-11-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a necrotizing vasculitis of medium size arteries that may affect various organs. The clinical appearance is very variable. The most common manifestations are of the skin, the peripheral nervous system presenting as mononeuritis multiplex and the mesenteric and renal blood vessels due to t...

journal_title：Zeitschrift fur Rheumatologie

authors： Schirmer JH,Holl-Ulrich K,Moosig F

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease with a prevalence of up to 1 % in the adult population. OBJECTIVE:This study describes the prevalence of RA diagnoses in outpatient health insurance claims data, based on different case definitions and stratified by age, sex and...

journal_title：Zeitschrift fur Rheumatologie

authors： Hense S,Luque Ramos A,Callhoff J,Albrecht K,Zink A,Hoffmann F

更新日期：2016-10-01 00:00:00

abstract：:Fabry's disease is a hereditary lipid storage disease with deposition of ceramides in nearly all tissues. The lipid deposition in the skin and the synovial compartments causes an enlargement of the skin, the joint capsules and the tendon sheaths, which are recognizable by low KV radiography. The bones of the hand main...

journal_title：Zeitschrift fur Rheumatologie

authors： Fischer E

更新日期：1986-01-01 00:00:00

abstract：:Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

journal_title：Zeitschrift fur Rheumatologie

authors： Valesová M,Trnavský K

更新日期：1990-07-01 00:00:00

abstract：:By means of the 99m-Tc-pertechnitate joint scintigraphy the authors try to document the effect of antirheumatic drugs in 62 patients with rheumatoid arthritis. By measuring the changes of the synovial blood circulation, conclusions are drawn as to the degree of inflammation. When trying to make a quantitative assessme...

journal_title：Zeitschrift fur Rheumatologie

authors： Kafarnik D,Semmler U,Pfannenstiel P,Miehlke K

更新日期：1981-03-01 00:00:00

abstract：:Commonly-used serological methods for the determination of Yersinia antibodies are based on the presence of agglutinins, which are frequently absent or of low titer when arthritis begins. Stool cultures are usually negative at that time, so many Yersinia infections are underdiagnosed. On the other hand, significant ag...

journal_title：Zeitschrift fur Rheumatologie

authors： Grasedyck K,Heesemann J

更新日期：1987-07-01 00:00:00

abstract：:Assessment of disease consequences (outcome) requires reliable, valid, and sensitive instruments. Psychometrically sound generic health-status instruments such as the SF-36 have been validated for many languages and are available in German. Instead, most disease specific instruments have been developed in English and ...

journal_title：Zeitschrift fur Rheumatologie

authors： Stucki G,Stucki S,Sangha O

更新日期：1997-10-01 00:00:00

abstract：:Osteoid osteomas are painful bone tumors that usually occur in childhood or adolescence. Despite the small size of the bony lesions osteoid osteomas can cause persistent pain. Pathogenesis has not been completely understood. Remission usually occurs within several months to years. Therefore surgical therapy is not ind...

journal_title：Zeitschrift fur Rheumatologie

authors： Hedrich CM,Fiebig B,Sallmann S,Bruck N,Thielemann F,Hahn G,Heubner G,Gahr M

更新日期：2008-03-01 00:00:00

abstract：:Three days after cholecystectomy, seven patients received a single dose of auranofin (5 tablets Ridaura = 4.35 mg gold). At defined time points thereafter the gold content in samples of blood, plasma, urine, bile, and feces was determined by instrumental neutron activation analysis (INAA). Maxima of the mean gold conc...

journal_title：Zeitschrift fur Rheumatologie

authors： Benn HP,Schnier C,Bauer E,Seiler KU,Elhöft H,Löffler H

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Leukotrienes and prostaglandines are important mediators of inflammation. While prostaglandine synthesis can be influenced by NSAIDs therapeutical approaches to the 5-lipoxygenase pathway are rare. Resinous extracts of Boswellia serrata (H15, indish incense), known from traditional ayurvedic medicine, decrea...

journal_title：Zeitschrift fur Rheumatologie

authors： Sander O,Herborn G,Rau R

更新日期：1998-02-01 00:00:00

abstract：:We report on a 39-year-old male patient suffering from seropositive rheumatoid arthritis who developed severe colitis during oral gold (Auranofin) therapy. So far, two further cases of colitis during oral, and 28 cases of enterocolitis during parenteral chrysotherapy have been described. The pathomechanism has not bee...

journal_title：Zeitschrift fur Rheumatologie

authors： Bross-Bach U,Saal JG,Hartmann F,Müller CA,Waller HD

更新日期：1987-07-01 00:00:00

abstract：:In rheumatic diseases, radiation synovectomy is a reliable method. Meanwhile, radiation synovectomy is an outpatient therapy. In addition, combination with arthroscopic synovectomy is an increasing therapeutic modality. In comparison to the hitherto inpatient modality, a greater lymphatic emigration of the radionuclid...

journal_title：Zeitschrift fur Rheumatologie

authors： Klett R,Puille M,Matter HP,Steiner D,Stürz H,Bauer R

更新日期：1999-08-01 00:00:00

abstract：:In recent years the great progress in knowledge on bone cell biology has allowed identification of molecular structures that can be targeted with pinpoint precision (druggable targets). Osteoclasts are regulated via the RANK-RANK-ligand (RANKL) signaling pathway and osteoblasts via the Wnt signaling pathway, both of w...

journal_title：Zeitschrift fur Rheumatologie

authors： Knauerhase A,Willenberg HS

更新日期：2016-06-01 00:00:00

abstract：:Systemic sclerosis is a rare rheumatologic disease that is characterised by skin and organ fibrosis as well as vascular changes and the occurrence of specific autoantibodies. It has a high morbidity and mortality while its manifestations show significant heterogeneity in patients. Thus, diagnosis and follow-up of pati...

journal_title：Zeitschrift fur Rheumatologie

authors： Becker MO,Distler O,Maurer B

更新日期：2019-06-01 00:00:00

abstract：:Several immuno-pathological aspects of polyarthritis following experimental infection with erysipelas in pigs were studied for two years. Aseptic and specifically pathogenfree animals were infected subcutaneously and intravenously-intraarticularly with living erysipeals bacteria (erysipelothrix rhusiopathiae) of serot...

journal_title：Zeitschrift fur Rheumatologie

authors： Trautwein G,Seidler D,Schulz LC,Drommer W,Weiss R,Böhm KH

更新日期：1976-05-01 00:00:00