[Ulcerative colitis caused by oral gold therapy in rheumatoid arthritis].

Abstract:

:We report on a 39-year-old male patient suffering from seropositive rheumatoid arthritis who developed severe colitis during oral gold (Auranofin) therapy. So far, two further cases of colitis during oral, and 28 cases of enterocolitis during parenteral chrysotherapy have been described. The pathomechanism has not been identified. Symptomatic therapy was applied, under which our patient recovered from intestinal discomfort in a few weeks. In differential diagnosis gold induced colitis has to be distinguished both from loose stools occurring during oral gold therapy, most probably caused by an inhibition of NA+K+ ATPase, and from colitis induced by concomitant application of nonsteroidal anti-inflammatory drugs.

journal_name

Z Rheumatol

authors

Bross-Bach U,Saal JG,Hartmann F,Müller CA,Waller HD

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

201-4

issue

4

eissn

0340-1855

issn

1435-1250

journal_volume

46

pub_type

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