Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis.

abstract：:This manuscript reviews carcinomas of the upper aerodigestive tract associated with genetic rearrangements of the nuclear protein of the testis (NUT) gene, also known as NUT midline carcinomas. The literature is reviewed regarding all reported cases of NUT midline carcinomas and the clinicopathologic features are disc...

journal_title：Advances in anatomic pathology

authors： Stelow EB,French CA

更新日期：2009-03-01 00:00:00

abstract：:Collecting duct carcinoma (CDC) and related tumors [ie, renal medullary carcinoma (RMC)] are rare types of highly aggressive renal cell carcinomas (RCC) with poor prognosis. Because of the rarity and diagnostic uncertainty of them, their molecular pathology and significance have not yet been fully elucidated. CDC, RMC...

journal_title：Advances in anatomic pathology

authors： Seo AN,Yoon G,Ro JY

更新日期：2017-03-01 00:00:00

abstract：:Recent advances in immunohistochemistry have made it possible to investigate lymphomas for the expression of a wide range of antigens in fixed tissues. Epitope retrieval, sensitive detection methods, and the availability of new monoclonal antibodies have all contributed to one's ability to perform detailed immunopheno...

journal_title：Advances in anatomic pathology

authors： Hsi ED,Yegappan S

更新日期：2001-07-01 00:00:00

abstract：:Gliomas are a large and diverse group of primary brain tumors that include those that are diffusely infiltrative and others that are well-circumscribed and low grade. Diffuse gliomas are currently classified by the World Health Organization as astrocytomas, oligodendrogliomas, or oligoastrocytomas and range in grade f...

journal_title：Advances in anatomic pathology

authors： Appin CL,Brat DJ

更新日期：2015-01-01 00:00:00

abstract：:Current World Health Organization (WHO) classification of lung adenocarcinomas includes noninvasive bronchioloalveolar carcinoma (BAC) and several patterns of invasive adenocarcinoma. The most common is a mixed subtype of adenocarcinoma. This group is very heterogenous and includes a wide spectrum of tumors ranging fr...

journal_title：Advances in anatomic pathology

authors： Dacic S

更新日期：2009-05-01 00:00:00

abstract：:This manuscript presents a review of infectious causes of gastritis aimed at the practicing anatomic pathologist. We shall highlight unique histologic findings and clinical attributes that will assist those analyzing endoscopically obtained mucosal biopsies of the stomach or resection specimens. ...

journal_title：Advances in anatomic pathology

authors： Yee EU,Kuo E,Goldsmith JD

更新日期：2018-07-01 00:00:00

abstract：:Plasmacytoid dendritic cells (PDCs) have perplexed pathologists for decades, undergoing multiple adjustments in nomenclature as their lineage and functions have been characterized. Although PDCs account for less than 0.1% of peripheral blood mononuclear cells, they serve as a principal source of interferon-alpha and a...

journal_title：Advances in anatomic pathology

authors： Jegalian AG,Facchetti F,Jaffe ES

更新日期：2009-11-01 00:00:00

abstract：:Our understanding of the natural history of breast cancer has evolved alongside technologies to study its genomic, transcriptomic, proteomic, and metabolomics landscapes. These technologies have helped decipher multiple molecular pathways dysregulated in breast cancer. First-generation 'omics analyses considered each ...

journal_title：Advances in anatomic pathology

authors： Kalita-de Croft P,Al-Ejeh F,McCart Reed AE,Saunus JM,Lakhani SR

更新日期：2016-11-01 00:00:00

abstract：:In this review, a recently published pattern-based risk stratification system of endocervical adenocarcinoma (EAC) is presented. This novel system evaluates the morphologic features of the tumor and establishes patterns that are associated with a particular tumor behavior. Patients with pattern A EAC do not develop ly...

journal_title：Advances in anatomic pathology

authors： Roma AA

更新日期：2015-11-01 00:00:00

abstract：:In recent years there have been a plethora of publications regarding the value of immunohistochemical studies in diagnosis in gynecological pathology. In many instances, papers are published initially that suggest that a certain antibody or panel of antibodies is of value in the diagnosis of a particular neoplasm and ...

journal_title：Advances in anatomic pathology

authors： McCluggage WG

更新日期：2004-05-01 00:00:00

abstract：:Invasive micropapillary carcinoma has been recently recognized as a rare but distinctive variant of carcinoma in various anatomic sites, including breast, urinary bladder, lung, and major salivary glands. Morphologically, it is characterized by small tight clusters of neoplastic cells floating in clear spaces resembli...

journal_title：Advances in anatomic pathology

authors： Nassar H

更新日期：2004-11-01 00:00:00

abstract：:The estrogen receptor (ER) is a regulator of cellular growth, proliferation, and differentiation. In addition to having prognostic value, ER is the most important biologic marker of therapeutic response in breast cancer. Some level of measurable ER protein is expressed in 70-80% of human breast. Immunohistochemistry i...

journal_title：Advances in anatomic pathology

authors： Diaz LK,Sneige N

更新日期：2005-01-01 00:00:00

abstract：:We report a case of a 14-year-old female with primary adenocarcinoma of the transverse colon. She was hospitalized after presenting with abdominal pain and signs of intestinal obstruction. There was no health antecedent or family history of neoplasia. Physical examination revealed a distended abdomen. Tenderness was e...

journal_title：Advances in anatomic pathology

authors： Galliani CA,Sanchez IC,D'Errico MM,Bisceglia M

更新日期：2015-05-01 00:00:00

abstract：:A variety of arthropods, protozoa, and helminths infect the skin and subcutaneous tissues and may be identified by anatomic pathologists in standard cytology and histology preparations. The specific organisms seen vary greatly with the patient's exposure history, including travel to or residence in endemic countries. ...

journal_title：Advances in anatomic pathology

authors： Norgan AP,Pritt BS

更新日期：2018-03-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a broad term that includes liver diseases characterized by abnormal hepatocellular accumulations of lipid that cannot be related to alcohol abuse. It may be found in both adults and children, particularly those who are obese or have insulin resistance. Steatohepatitis is a ...

journal_title：Advances in anatomic pathology

authors： Aly FZ,Kleiner DE

更新日期：2011-07-01 00:00:00

abstract：:For many pathologists, the roles of the medical director are not clearly distinguished from other medical leadership and management duties, such as those of the chair of pathology or a section head of anatomic pathology. We describe the evolution in the understanding of the roles of the medical director as defined by ...

journal_title：Advances in anatomic pathology

authors： Hernandez JS

更新日期：2011-01-01 00:00:00

abstract：:The development of small-molecule inhibitors of the epidermal growth factor receptor (EGFR) resulted in new therapeutic options for patients with advanced lung cancer. It was clear from the experience with targeted therapy for breast cancer that a new standardized assay procedure for assessing and predicting the effec...

journal_title：Advances in anatomic pathology

authors： Dacic S

更新日期：2008-07-01 00:00:00

abstract：:Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In recent years, there has been considerable progress in efforts to reveal the molecular landscape of these tumors, although it is still limited and appears to be only the tip of the iceberg. Genomic aberrations, especially specific chr...

journal_title：Advances in anatomic pathology

authors： Toper MH,Sarioglu S

更新日期：2021-01-04 00:00:00

abstract：:Inflammatory osteolysis is a relatively frequent and incapacitating complication of rheumatoid arthritis and other inflammatory diseases, and is induced by accelerated osteoclast recruitment and activation in bone under the aegis of cytokines produced in the inflammatory environment. The success of antitumor necrosis ...

journal_title：Advances in anatomic pathology

authors： Wei S,Siegal GP

更新日期：2007-01-01 00:00:00

abstract：:The topic of hereditary gynecologic malignancies readily evokes associations between Lynch syndrome and endometrial adenocarcinoma, or between BRCA mutations and tubo-ovarian serous carcinoma, but other familial associations are less well-known. Two hereditary syndromes are known to be related to uterine mesenchymal t...

journal_title：Advances in anatomic pathology

authors： Joehlin-Price AS,Garg K

更新日期：2018-03-01 00:00:00

abstract：:Intraoperative consultation remains an invaluable tool in the initial evaluation of surgically excised specimens. Good communication is required between the pathologist and surgeon to obtain the best care for their mutual patient. Intraoperative consultation (frozen section, FS) provides a preliminary diagnosis for th...

journal_title：Advances in anatomic pathology

authors： Somerset HL,Kleinschmidt-DeMasters BK

更新日期：2011-11-01 00:00:00

abstract：:Atypical cribriform lesions of the prostate gland consist of cribriform and rarely solid proliferation of prostate glands populated with cytologically atypical cells with partial or complete basal cell lining. It may represent cribriform "high-grade prostatic intraepithelial neoplasia" (HGPIN) or "intraductal carcinom...

journal_title：Advances in anatomic pathology

authors： Shah RB,Zhou M

更新日期：2012-07-01 00:00:00

abstract：:The Bethesda System for Reporting Thyroid Cytopathology is a standardized reporting system for classifying thyroid fine-needle aspiration results comprising of 6 diagnostic categories with unique risks of malignancy and recommendations for clinical management. The majority of thyroid nodules are benign; however, up to...

journal_title：Advances in anatomic pathology

authors： Wong LQ,Baloch ZW

更新日期：2012-09-01 00:00:00

abstract：:Diffuse aggressive B-cell lymphomas comprise a relatively common and increasingly diverse group of neoplasms. Newer modalities including gene expression profiling and an increasing panel of immunohistochemical markers have contributed to greater accuracy in defining these entities. Attention is paid not only to the ne...

journal_title：Advances in anatomic pathology

authors： Said J

更新日期：2009-07-01 00:00:00

abstract：:Papillary renal cell carcinoma is the second most common malignant renal epithelial tumor and constitutes approximately 15% of renal cell tumors. However, papillary architecture is neither unique to papillary renal cell carcinoma, nor do all papillary renal cell carcinomas show exclusive papillary histology. Many of t...

journal_title：Advances in anatomic pathology

authors： Tickoo SK,Reuter VE

更新日期：2011-03-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is a vascular tumor of low to intermediate malignancy that was initially described in the soft tissue. Since then, epithelioid hemangioendothelioma has been described in various anatomic sites including parenchymal tissues and the bone. In the bone, these tumors must not only be distin...

journal_title：Advances in anatomic pathology

authors： Weissferdt A,Moran CA

更新日期：2014-07-01 00:00:00

abstract：:Leukoplakia as a medical term has been encumbered by a hodgepodge of synonyms and interpretations. It also has been a term associated with strong emotions with respect to an implied malignant potential. It now is regarded as potentially malignant, with varying degrees of risk for transformation. Leukoplakia at its maj...

journal_title：Advances in anatomic pathology

authors： Suarez P,Batsakis JG,el-Naggar AK

更新日期：1998-05-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a systemic, progressive, and fatal condition affecting almost exclusively women in their reproductive years. LAM most often occurs as a sporadic disease, but also occurs in women with tuberous sclerosis complex (TSC) (syndromic LAM). There are no pathologic differences between sporadi...

journal_title：Advances in anatomic pathology

authors： Bisceglia M,D'Alessandro V,Simeone A,Ben-Dor D,Pasquinelli G

更新日期：2010-11-01 00:00:00

abstract：:Approximately 25% of patients with stage I (node negative) breast cancer relapse at a rate similar to those with stage II disease. Inadvertent pathologic "understaging" of lymph node status is one plausible explanation for this phenomenon. While many studies have shown that additional sectioning +/- immunohistochemica...

journal_title：Advances in anatomic pathology

authors： Mies C,Schlesselman JJ

更新日期：2000-05-01 00:00:00

abstract：:Central nervous system (CNS) neoplasms can be diagnostically challenging, due to remarkably wide ranges in histologic appearance, biologic behavior, and therapeutic approach. Nevertheless, accurate diagnosis is the critical first step in providing optimal patient care. As with other oncology-based specialties, there i...

journal_title：Advances in anatomic pathology

authors： Fuller CE,Perry A

更新日期：2005-07-01 00:00:00