Update on fatty liver disease and steatohepatitis.

abstract：:Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In recent years, there has been considerable progress in efforts to reveal the molecular landscape of these tumors, although it is still limited and appears to be only the tip of the iceberg. Genomic aberrations, especially specific chr...

journal_title：Advances in anatomic pathology

authors： Toper MH,Sarioglu S

更新日期：2021-01-04 00:00:00

abstract：:Microarrays began to be used to study gene expression profiles in the mid-1990s, but it was only after 2000 that serious attempts have been made to apply this technology to investigate sarcomas. Microarray technologies provide a comprehensive survey of active molecular pathways and potential molecular targets for diag...

journal_title：Advances in anatomic pathology

authors： Nielsen TO

更新日期：2006-07-01 00:00:00

abstract：:The differential diagnosis of neuroendocrine neoplasms of the larynx is broad and includes lesions of epithelial, mesenchymal, and neuroectodermal origin. These lesions have overlapping clinical and pathologic aspects and must be carefully considered in the differential diagnosis of laryngeal neoplasms. The prognosis ...

journal_title：Advances in anatomic pathology

authors： Hunt JL,Ferlito A,Hellquist H,Rinaldo A,Skálová A,Slootweg PJ,Willems SM,Cardesa A

更新日期：2017-05-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common form of kidney cancer in adults. RCC is a significant challenge for pathologic diagnosis and clinical management. The primary approach to diagnosis is by light microscopy, using the World Health Organization (WHO) classification system, which defines histopathologic tumor ...

journal_title：Advances in anatomic pathology

authors： Young AN,Master VA,Paner GP,Wang MD,Amin MB

更新日期：2008-01-01 00:00:00

abstract：:Digital imaging has progressed at a rapid rate and is likely to eventually replace chemical photography in most areas of professional and amateur digital image acquisition. In pathology, digital microscopy has implications beyond that of taking a photograph. The arguments for adopting this new medium are compelling, a...

journal_title：Advances in anatomic pathology

authors： Leong FJ,Leong AS

更新日期：2003-03-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER-2) is over-expressed in 15% to 30% of breast cancers and is a poor prognostic marker in node-positive patients. HER-2 expression is an indicator of greater sensitivity to anthracycline-based chemotherapy and is the major criterion for selection for treatment with the anti-...

journal_title：Advances in anatomic pathology

authors： Leong TY,Leong AS

更新日期：2006-09-01 00:00:00

abstract：:The topic of hereditary gynecologic malignancies readily evokes associations between Lynch syndrome and endometrial adenocarcinoma, or between BRCA mutations and tubo-ovarian serous carcinoma, but other familial associations are less well-known. Two hereditary syndromes are known to be related to uterine mesenchymal t...

journal_title：Advances in anatomic pathology

authors： Joehlin-Price AS,Garg K

更新日期：2018-03-01 00:00:00

abstract：:Digital pathology systems offer pathologists an alternate, emerging mechanism to manage and interpret information. They offer increasingly fast and scalable hardware platforms for slide scanning and software that facilitates remote viewing, slide conferencing, archiving, and image analysis. Deployed initially and vali...

journal_title：Advances in anatomic pathology

authors： Cornish TC,Swapp RE,Kaplan KJ

更新日期：2012-05-01 00:00:00

abstract：:Data from the past 6 years have shown that the presence of any amount of cribriform (or more comprehensively, large acinar cribriform to papillary) pattern of invasive prostate cancer is associated with adverse pathologic features and leads to uniquely adverse outcomes. Sixteen papers and numerous abstracts have reach...

journal_title：Advances in anatomic pathology

authors： Iczkowski KA,Paner GP,Van der Kwast T

更新日期：2018-01-01 00:00:00

abstract：:Diffuse aggressive B-cell lymphomas comprise a relatively common and increasingly diverse group of neoplasms. Newer modalities including gene expression profiling and an increasing panel of immunohistochemical markers have contributed to greater accuracy in defining these entities. Attention is paid not only to the ne...

journal_title：Advances in anatomic pathology

authors： Said J

更新日期：2009-07-01 00:00:00

abstract：:CD 117 (KIT) is a transmembrane, tyrosine kinase growth factor receptor which is expressed on numerous diverse fetal and adult cells including hematopoietic cells, mast cells, melanocytes, germ cells, and the interstitial cells of Cajal. Its expression in tumors is also diverse, but with selective use and attention to...

journal_title：Advances in anatomic pathology

authors： Gibson PC,Cooper K

更新日期：2002-01-01 00:00:00

abstract：:We report a case of a 14-year-old female with primary adenocarcinoma of the transverse colon. She was hospitalized after presenting with abdominal pain and signs of intestinal obstruction. There was no health antecedent or family history of neoplasia. Physical examination revealed a distended abdomen. Tenderness was e...

journal_title：Advances in anatomic pathology

authors： Galliani CA,Sanchez IC,D'Errico MM,Bisceglia M

更新日期：2015-05-01 00:00:00

abstract：:The encapsulated and noninvasive follicular variant of papillary thyroid carcinoma has been recently reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). These tumors demonstrate indolent behavior. This change in nomenclature will have great clinical impact by avoiding ...

journal_title：Advances in anatomic pathology

authors： Basolo F,Macerola E,Ugolini C,Poller DN,Baloch Z

更新日期：2017-09-01 00:00:00

abstract：:Leukoplakia as a medical term has been encumbered by a hodgepodge of synonyms and interpretations. It also has been a term associated with strong emotions with respect to an implied malignant potential. It now is regarded as potentially malignant, with varying degrees of risk for transformation. Leukoplakia at its maj...

journal_title：Advances in anatomic pathology

authors： Suarez P,Batsakis JG,el-Naggar AK

更新日期：1998-05-01 00:00:00

abstract：:Desmoplastic melanoma (DM) is a relatively rare cytomorphologic variant of melanoma with a marked propensity for perineural invasion (PNI). Historically, DMs that display PNI have been grouped under the umbrella term of neurotropic melanoma (NM). However, definitions for NM and desmoplastic NM are not consistent in th...

journal_title：Advances in anatomic pathology

authors： Frydenlund N,Mahalingam M

更新日期：2015-07-01 00:00:00

abstract：:Immunohistochemistry (IHC) is routinely performed in most laboratories, and other than purchase of commercially available antibodies, requires no additional equipment or reagents. As such, IHC is an accessible and relatively inexpensive test and one that can be performed quite quickly. This is in sharp contrast to gen...

journal_title：Advances in anatomic pathology

authors： Oh KS,Mahalingam M

更新日期：2019-11-01 00:00:00

abstract：:Papillary renal cell carcinoma is the second most common malignant renal epithelial tumor and constitutes approximately 15% of renal cell tumors. However, papillary architecture is neither unique to papillary renal cell carcinoma, nor do all papillary renal cell carcinomas show exclusive papillary histology. Many of t...

journal_title：Advances in anatomic pathology

authors： Tickoo SK,Reuter VE

更新日期：2011-03-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a systemic, progressive, and fatal condition affecting almost exclusively women in their reproductive years. LAM most often occurs as a sporadic disease, but also occurs in women with tuberous sclerosis complex (TSC) (syndromic LAM). There are no pathologic differences between sporadi...

journal_title：Advances in anatomic pathology

authors： Bisceglia M,D'Alessandro V,Simeone A,Ben-Dor D,Pasquinelli G

更新日期：2010-11-01 00:00:00

abstract：:Pathology has benefited from advanced innovation with novel technology to implement a digital solution. Whole slide imaging is a disruptive technology where glass slides are scanned to produce digital images. There have been significant advances in whole slide scanning hardware and software that have allowed for ready...

journal_title：Advances in anatomic pathology

authors： Hanna MG,Parwani A,Sirintrapun SJ

更新日期：2020-07-01 00:00:00

abstract：:This paper reviews the pathologic features of lesions which are oncocytic and involve classic endocrine organs. The history of the oncocytic cell, its morphologic and ultrastructural features, and important immunohistochemical findings are reviewed. Oncocytic proliferations including non-neoplastic and neoplastic of t...

journal_title：Advances in anatomic pathology

authors： Canberk S,LiVolsi VA,Baloch Z

更新日期：2014-03-01 00:00:00

abstract：:Dysproteinemia is a clinical state characterized by abnormal, often excessive, synthesis of immunoglobulin (Ig) molecules or subunits. Dysproteinemia results from clonal proliferation of plasma cells or B lymphocytes. The abnormal circulating Ig molecules or subunits (most commonly free light chains) reach the glomeru...

journal_title：Advances in anatomic pathology

authors： Markowitz GS

更新日期：2004-01-01 00:00:00

abstract：:Inflammatory skin diseases encompass a vast array of conditions. The field continues to expand and evolve with resurgence of conditions, through newly recognized medication adverse effects, and via more detailed descriptions of known dermatoses. The importance of clinicopathologic correlation and an up to date knowled...

journal_title：Advances in anatomic pathology

authors： Penn L,Rothman L,Sutton AM,Brinster NK,Vidal CI

更新日期：2019-01-01 00:00:00

abstract：:Alveolar soft-part sarcoma (ASPS) is one of the most unusual of the soft tissue sarcomas. Although it most commonly arises in the fascial planes or skeletal muscles of the lower extremities in adults, and in the head and neck region in children, it has also been documented in extraskeletal muscle locations, especially...

journal_title：Advances in anatomic pathology

authors： Ordóñez NG

更新日期：1999-05-01 00:00:00

abstract：:The common sources of ionizing radiation exposure to the thyroid gland in humans are accidental environmental exposure and medical, therapeutic, or diagnostic irradiation. Radiation often induces notable histologic changes in the thyroid tissue and is a well-established risk factor for benign and malignant thyroid tum...

journal_title：Advances in anatomic pathology

authors： Nikiforov YE,Gnepp DR

更新日期：1999-03-01 00:00:00

abstract：:Inflammatory osteolysis is a relatively frequent and incapacitating complication of rheumatoid arthritis and other inflammatory diseases, and is induced by accelerated osteoclast recruitment and activation in bone under the aegis of cytokines produced in the inflammatory environment. The success of antitumor necrosis ...

journal_title：Advances in anatomic pathology

authors： Wei S,Siegal GP

更新日期：2007-01-01 00:00:00

abstract：:Well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL) form the largest subgroup of liposarcomas, and represent a morphologic and behavioral spectrum of 1 disease entity, which arises typically in middle to late adult life, most frequently within the retroperitoneum or extremities. DDL is defined...

journal_title：Advances in anatomic pathology

authors： Thway K,Jones RL,Noujaim J,Zaidi S,Miah AB,Fisher C

更新日期：2016-01-01 00:00:00

abstract：:Neoplasms and pseudotumors of the temporomandibular joint (TMJ) are very uncommon. Early recognition of such will prevent therapeutic delay and may have a dramatic impact on patient morbidity and mortality. Included in rare TMJ lesions are the following: 1) synovial chondromatosis, 2) osteochondroma, 3) osteoma, 4) os...

journal_title：Advances in anatomic pathology

authors： Warner BF,Luna MA,Robert Newland T

更新日期：2000-11-01 00:00:00

abstract：:Intrahepatic ductular reaction is a pathologic proliferation of phenotypical biliary channels. Ductular reactions aim to restore compromised physiological function after liver injury and are one of the archetypal responses of the liver to a wide variety of etiologies, among them are parenchymal loss, biliary tract dis...

journal_title：Advances in anatomic pathology

authors： Jain R,Clark I

更新日期：2021-01-19 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare aggressive cutaneous malignancy of the elderly and immunocompromised populations. The clinical presentation of MCC is nonspecific, with the majority of cases presenting as localized skin involvement. Histologically and immunophenotypically, MCC is defined by both neuroendocrine an...

journal_title：Advances in anatomic pathology

authors： Calder KB,Smoller BR

更新日期：2010-05-01 00:00:00

abstract：:Gastrointestinal (GI) tract tumors with melanocytic differentiation may present significant diagnostic challenges both for the pathologist and the clinician. This comprehensive review discusses the relatively common as well as rare entities that have melanocytic differentiation in the GI tract. Clinical, histologic, i...

journal_title：Advances in anatomic pathology

authors： Karamchandani DM,Patil DT,Goldblum JR

更新日期：2013-11-01 00:00:00