Renal epithelial neoplasms: diagnostic applications of gene expression profiling.

abstract：:The common sources of ionizing radiation exposure to the thyroid gland in humans are accidental environmental exposure and medical, therapeutic, or diagnostic irradiation. Radiation often induces notable histologic changes in the thyroid tissue and is a well-established risk factor for benign and malignant thyroid tum...

journal_title：Advances in anatomic pathology

authors： Nikiforov YE,Gnepp DR

更新日期：1999-03-01 00:00:00

abstract：:Central nervous system (CNS) neoplasms can be diagnostically challenging, due to remarkably wide ranges in histologic appearance, biologic behavior, and therapeutic approach. Nevertheless, accurate diagnosis is the critical first step in providing optimal patient care. As with other oncology-based specialties, there i...

journal_title：Advances in anatomic pathology

authors： Fuller CE,Perry A

更新日期：2005-07-01 00:00:00

abstract：:Desmoplastic melanoma (DM) is a relatively rare cytomorphologic variant of melanoma with a marked propensity for perineural invasion (PNI). Historically, DMs that display PNI have been grouped under the umbrella term of neurotropic melanoma (NM). However, definitions for NM and desmoplastic NM are not consistent in th...

journal_title：Advances in anatomic pathology

authors： Frydenlund N,Mahalingam M

更新日期：2015-07-01 00:00:00

abstract：:The diagnosis of minimal prostatic adenocarcinoma can be challenging on prostate needle biopsy, and immunohistochemistry may be used to support the diagnosis of cancer. The International Society of Urologic Pathology currently recommends the use of the basal cell markers high-molecular-weight cytokeraratin and p63, an...

journal_title：Advances in anatomic pathology

authors： Giannico GA,Arnold SA,Gellert LL,Hameed O

更新日期：2017-01-01 00:00:00

abstract：:Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In recent years, there has been considerable progress in efforts to reveal the molecular landscape of these tumors, although it is still limited and appears to be only the tip of the iceberg. Genomic aberrations, especially specific chr...

journal_title：Advances in anatomic pathology

authors： Toper MH,Sarioglu S

更新日期：2021-01-04 00:00:00

abstract：:Invasive micropapillary carcinoma has been recently recognized as a rare but distinctive variant of carcinoma in various anatomic sites, including breast, urinary bladder, lung, and major salivary glands. Morphologically, it is characterized by small tight clusters of neoplastic cells floating in clear spaces resembli...

journal_title：Advances in anatomic pathology

authors： Nassar H

更新日期：2004-11-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare aggressive cutaneous malignancy of the elderly and immunocompromised populations. The clinical presentation of MCC is nonspecific, with the majority of cases presenting as localized skin involvement. Histologically and immunophenotypically, MCC is defined by both neuroendocrine an...

journal_title：Advances in anatomic pathology

authors： Calder KB,Smoller BR

更新日期：2010-05-01 00:00:00

abstract：:The concept of Waldenstrom macroglobulinemia has evolved from the original description of a clinical syndrome to its more recent designation as a distinct clinicopathologic entity, that is, lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM), in the World Health Organization (WHO) classification and by t...

journal_title：Advances in anatomic pathology

authors： Lin P,Medeiros LJ

更新日期：2005-09-01 00:00:00

abstract：:CD 117 (KIT) is a transmembrane, tyrosine kinase growth factor receptor which is expressed on numerous diverse fetal and adult cells including hematopoietic cells, mast cells, melanocytes, germ cells, and the interstitial cells of Cajal. Its expression in tumors is also diverse, but with selective use and attention to...

journal_title：Advances in anatomic pathology

authors： Gibson PC,Cooper K

更新日期：2002-01-01 00:00:00

abstract：:The main purpose of urine cytology is to detect high-grade urothelial carcinoma. With this principle in mind, The Paris System (TPS) Working Group, composed of cytopathologists, surgical pathologists, and urologists, has proposed and published a standardized reporting system that includes specific diagnostic categorie...

journal_title：Advances in anatomic pathology

authors： Barkan GA,Wojcik EM,Nayar R,Savic-Prince S,Quek ML,Kurtycz DF,Rosenthal DL

更新日期：2016-07-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is a vascular tumor of low to intermediate malignancy that was initially described in the soft tissue. Since then, epithelioid hemangioendothelioma has been described in various anatomic sites including parenchymal tissues and the bone. In the bone, these tumors must not only be distin...

journal_title：Advances in anatomic pathology

authors： Weissferdt A,Moran CA

更新日期：2014-07-01 00:00:00

abstract：:Immunohistochemistry (IHC) is routinely performed in most laboratories, and other than purchase of commercially available antibodies, requires no additional equipment or reagents. As such, IHC is an accessible and relatively inexpensive test and one that can be performed quite quickly. This is in sharp contrast to gen...

journal_title：Advances in anatomic pathology

authors： Oh KS,Mahalingam M

更新日期：2019-11-01 00:00:00

abstract：:This article reviews the recent dermatopathology literature regarding cutaneous adnexal neoplasms, with emphasis on new and underrecognized entities, "old entities" with new findings, advances in immunohistochemistry, and new findings in relation to inherited disorders associated with cutaneous adnexal neoplasms. ...

journal_title：Advances in anatomic pathology

authors： Ali SM,Sangueza OP

更新日期：2013-09-01 00:00:00

abstract：:Fluorescence in-situ hybridization (FISH) has arisen as a novel ancillary test for the pathological diagnosis of melanoma. It is an outgrowth of studies using comparative genomic hybridization, a technique capable of surveying the entire genome for DNA copy number changes. An original report published in 2009 showed h...

journal_title：Advances in anatomic pathology

authors： Song J,Mooi WJ,Petronic-Rosic V,Shea CR,Stricker T,Krausz T

更新日期：2011-05-01 00:00:00

abstract：:Paratesticular mesotheliomas are rare tumors with 223 cases described so far. The sole plausible causative factor so far ascertained in the pathogenesis of these tumors is asbestos, which however is found in only around 30% to 40% of such cases. The age range of affected individuals is wide, mostly adults and the elde...

journal_title：Advances in anatomic pathology

authors： Bisceglia M,Dor DB,Carosi I,Vairo M,Pasquinelli G

更新日期：2010-01-01 00:00:00

abstract：:Descriptions of poorly differentiated thyroid carcinomas, tumors with outcomes midway between that associated with well-differentiated and anaplastic carcinomas, have been prominent in the literature of the recent past. The neoplasms are characterized by the finding of poorly differentiated areas within papillary and ...

journal_title：Advances in anatomic pathology

authors： Nishiyama RH

更新日期：1999-09-01 00:00:00

abstract：:Thyroid microcarcinoma, defined as a thyroid tumor measuring 1 cm or less, is an extremely indolent tumor. Papillary microcarcinoma, the most common subtype, is often identified incidentally in a thyroid removed for benign clinical nodules or diffuse processes (eg, thyroiditis). In this clinical situation, over 99% ar...

journal_title：Advances in anatomic pathology

authors： Baloch ZW,LiVolsi VA

更新日期：2006-03-01 00:00:00

abstract：:Tissue microarrays (TMAs) offer the potential to rapidly translate genomics and basic science research findings to practical clinical application. This is particularly true in the field of cancer biomarker research, where TMAs can be used for candidate biomarker validation and association with patient clinical, pathol...

journal_title：Advances in anatomic pathology

authors： Datta MW,True LD,Nelson PS,Amin MB

更新日期：2007-11-01 00:00:00

abstract：:Intrahepatic ductular reaction is a pathologic proliferation of phenotypical biliary channels. Ductular reactions aim to restore compromised physiological function after liver injury and are one of the archetypal responses of the liver to a wide variety of etiologies, among them are parenchymal loss, biliary tract dis...

journal_title：Advances in anatomic pathology

authors： Jain R,Clark I

更新日期：2021-01-19 00:00:00

abstract：:The analysis of a large number of tumor tissues with conventional techniques of molecular pathology is tedious and slow. The authors recently developed the tissue microarray technology that makes it possible to sample up to 1,000 tumors on one glass slide, which then can be analyzed by fluorescence in situ hybridizati...

journal_title：Advances in anatomic pathology

authors： Moch H,Kononen T,Kallioniemi OP,Sauter G

更新日期：2001-01-01 00:00:00

abstract：:Leukoplakia as a medical term has been encumbered by a hodgepodge of synonyms and interpretations. It also has been a term associated with strong emotions with respect to an implied malignant potential. It now is regarded as potentially malignant, with varying degrees of risk for transformation. Leukoplakia at its maj...

journal_title：Advances in anatomic pathology

authors： Suarez P,Batsakis JG,el-Naggar AK

更新日期：1998-05-01 00:00:00

abstract：:Nephropathology is a specialized field requiring routine tissue evaluation by immunofluorescence (IF), electron microscopy (EM), and light microscopy, and has published standards of best practice. Actual practices are less well documented. We therefore evaluated actual practices in nephropathology and their divergence...

journal_title：Advances in anatomic pathology

authors： Pullman JM,Ferrario F,Nast CC

更新日期：2007-03-01 00:00:00

abstract：:Endometriosis is a relatively common condition in which endometrial tissue is established in locations outside the uterus where, like the eutopic endometrium, it responds to hormonal stimuli and develops internal bleeding, inflammation, and fibrosis. These changes are associated with chronic and often debilitating cyc...

journal_title：Advances in anatomic pathology

authors： Arafah M,Rashid S,Akhtar M

更新日期：2021-01-01 00:00:00

abstract：:As genomic characterization becomes increasingly necessary for accurate diagnosis of tumors of the central nervous system, identification of rapidly assessible biomarkers is equally important to avoid excessive cost and delay in initiation of therapy. This article reviews novel immunohistochemical markers that may be ...

journal_title：Advances in anatomic pathology

authors： Meredith DM

更新日期：2020-05-01 00:00:00

abstract：:Plasmacytoid dendritic cells (PDCs) have perplexed pathologists for decades, undergoing multiple adjustments in nomenclature as their lineage and functions have been characterized. Although PDCs account for less than 0.1% of peripheral blood mononuclear cells, they serve as a principal source of interferon-alpha and a...

journal_title：Advances in anatomic pathology

authors： Jegalian AG,Facchetti F,Jaffe ES

更新日期：2009-11-01 00:00:00

abstract：:Endometrial endometrioid adenocarcinoma (EEC) is the most common malignancy of the female genital tract, partly attributable to chronic estrogen exposure secondary to increased obesity rates. Tumor stage, which in most cases is based on depth of invasion (DOI), is of critical importance in determining if additional tr...

journal_title：Advances in anatomic pathology

authors： Cole AJ,Quick CM

更新日期：2013-05-01 00:00:00

abstract：:Intraoperative consultation remains an invaluable tool in the initial evaluation of surgically excised specimens. Good communication is required between the pathologist and surgeon to obtain the best care for their mutual patient. Intraoperative consultation (frozen section, FS) provides a preliminary diagnosis for th...

journal_title：Advances in anatomic pathology

authors： Somerset HL,Kleinschmidt-DeMasters BK

更新日期：2011-11-01 00:00:00

abstract：:Myoepithelial neoplasms represent a heterogeneous group of tumors of which classification is incomplete and evolving. Those of the soft tissues often form genetically distinct subgroups that differ from those arising within salivary glands. Soft-tissue myoepithelial tumors (including mixed tumors that show true glandu...

journal_title：Advances in anatomic pathology

authors： Thway K,Fisher C

更新日期：2014-11-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a broad term that includes liver diseases characterized by abnormal hepatocellular accumulations of lipid that cannot be related to alcohol abuse. It may be found in both adults and children, particularly those who are obese or have insulin resistance. Steatohepatitis is a ...

journal_title：Advances in anatomic pathology

authors： Aly FZ,Kleiner DE

更新日期：2011-07-01 00:00:00

abstract：:Well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL) form the largest subgroup of liposarcomas, and represent a morphologic and behavioral spectrum of 1 disease entity, which arises typically in middle to late adult life, most frequently within the retroperitoneum or extremities. DDL is defined...

journal_title：Advances in anatomic pathology

authors： Thway K,Jones RL,Noujaim J,Zaidi S,Miah AB,Fisher C

更新日期：2016-01-01 00:00:00