Carcinomas with micropapillary morphology: clinical significance and current concepts.

abstract：:Recent advances in immunohistochemistry have made it possible to investigate lymphomas for the expression of a wide range of antigens in fixed tissues. Epitope retrieval, sensitive detection methods, and the availability of new monoclonal antibodies have all contributed to one's ability to perform detailed immunopheno...

journal_title：Advances in anatomic pathology

authors： Hsi ED,Yegappan S

更新日期：2001-07-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is a vascular tumor of low to intermediate malignancy that was initially described in the soft tissue. Since then, epithelioid hemangioendothelioma has been described in various anatomic sites including parenchymal tissues and the bone. In the bone, these tumors must not only be distin...

journal_title：Advances in anatomic pathology

authors： Weissferdt A,Moran CA

更新日期：2014-07-01 00:00:00

abstract：:Approximately 25% of patients with stage I (node negative) breast cancer relapse at a rate similar to those with stage II disease. Inadvertent pathologic "understaging" of lymph node status is one plausible explanation for this phenomenon. While many studies have shown that additional sectioning +/- immunohistochemica...

journal_title：Advances in anatomic pathology

authors： Mies C,Schlesselman JJ

更新日期：2000-05-01 00:00:00

abstract：:Follicular dendritic cell sarcoma (FDCS) is an intermediate-grade malignancy of follicular dendritic cells, which are derived from mesenchymal stem cells. Nodal FDCS is well-recognized. However, when it occurs at an extranodal site, it may not be recognized and is often misdiagnosed. These tumors exhibit a variable sp...

journal_title：Advances in anatomic pathology

authors： Kaur R,Mehta J,Borges A

更新日期：2021-01-01 00:00:00

abstract：:Endometrial endometrioid adenocarcinoma (EEC) is the most common malignancy of the female genital tract, partly attributable to chronic estrogen exposure secondary to increased obesity rates. Tumor stage, which in most cases is based on depth of invasion (DOI), is of critical importance in determining if additional tr...

journal_title：Advances in anatomic pathology

authors： Cole AJ,Quick CM

更新日期：2013-05-01 00:00:00

abstract：:Fluorescence in-situ hybridization (FISH) has arisen as a novel ancillary test for the pathological diagnosis of melanoma. It is an outgrowth of studies using comparative genomic hybridization, a technique capable of surveying the entire genome for DNA copy number changes. An original report published in 2009 showed h...

journal_title：Advances in anatomic pathology

authors： Song J,Mooi WJ,Petronic-Rosic V,Shea CR,Stricker T,Krausz T

更新日期：2011-05-01 00:00:00

abstract：:Neoplasms and pseudotumors of the temporomandibular joint (TMJ) are very uncommon. Early recognition of such will prevent therapeutic delay and may have a dramatic impact on patient morbidity and mortality. Included in rare TMJ lesions are the following: 1) synovial chondromatosis, 2) osteochondroma, 3) osteoma, 4) os...

journal_title：Advances in anatomic pathology

authors： Warner BF,Luna MA,Robert Newland T

更新日期：2000-11-01 00:00:00

abstract：:The diagnosis of minimal prostatic adenocarcinoma can be challenging on prostate needle biopsy, and immunohistochemistry may be used to support the diagnosis of cancer. The International Society of Urologic Pathology currently recommends the use of the basal cell markers high-molecular-weight cytokeraratin and p63, an...

journal_title：Advances in anatomic pathology

authors： Giannico GA,Arnold SA,Gellert LL,Hameed O

更新日期：2017-01-01 00:00:00

abstract：:The Bethesda System for Reporting Thyroid Cytopathology is a standardized reporting system for classifying thyroid fine-needle aspiration results comprising of 6 diagnostic categories with unique risks of malignancy and recommendations for clinical management. The majority of thyroid nodules are benign; however, up to...

journal_title：Advances in anatomic pathology

authors： Wong LQ,Baloch ZW

更新日期：2012-09-01 00:00:00

abstract：:The encapsulated and noninvasive follicular variant of papillary thyroid carcinoma has been recently reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). These tumors demonstrate indolent behavior. This change in nomenclature will have great clinical impact by avoiding ...

journal_title：Advances in anatomic pathology

authors： Basolo F,Macerola E,Ugolini C,Poller DN,Baloch Z

更新日期：2017-09-01 00:00:00

abstract：:The topic of hereditary gynecologic malignancies readily evokes associations between Lynch syndrome and endometrial adenocarcinoma, or between BRCA mutations and tubo-ovarian serous carcinoma, but other familial associations are less well-known. Two hereditary syndromes are known to be related to uterine mesenchymal t...

journal_title：Advances in anatomic pathology

authors： Joehlin-Price AS,Garg K

更新日期：2018-03-01 00:00:00

abstract：:Distinction between endometrioid and serous carcinomas of the endometrium has important prognostic and therapeutic implications. Misdiagnosing a serous carcinoma as endometrioid can have significant consequences for the patient and pathologist. Although many cases are straightforward and easy to classify, there are oc...

journal_title：Advances in anatomic pathology

authors： Garg K,Soslow RA

更新日期：2012-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a broad term that includes liver diseases characterized by abnormal hepatocellular accumulations of lipid that cannot be related to alcohol abuse. It may be found in both adults and children, particularly those who are obese or have insulin resistance. Steatohepatitis is a ...

journal_title：Advances in anatomic pathology

authors： Aly FZ,Kleiner DE

更新日期：2011-07-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare aggressive cutaneous malignancy of the elderly and immunocompromised populations. The clinical presentation of MCC is nonspecific, with the majority of cases presenting as localized skin involvement. Histologically and immunophenotypically, MCC is defined by both neuroendocrine an...

journal_title：Advances in anatomic pathology

authors： Calder KB,Smoller BR

更新日期：2010-05-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) has distinct morphologic features and can be identified in the majority of cases by routine hematoxylin and eosin (H&E)-stained formalin-fixed paraffin-embedded sections. However, distinguishing a well-differentiated HCC from normal or regenerative tissue may be very difficult in some ca...

journal_title：Advances in anatomic pathology

authors： Varma V,Cohen C

更新日期：2004-09-01 00:00:00

abstract：:Our understanding of the natural history of breast cancer has evolved alongside technologies to study its genomic, transcriptomic, proteomic, and metabolomics landscapes. These technologies have helped decipher multiple molecular pathways dysregulated in breast cancer. First-generation 'omics analyses considered each ...

journal_title：Advances in anatomic pathology

authors： Kalita-de Croft P,Al-Ejeh F,McCart Reed AE,Saunus JM,Lakhani SR

更新日期：2016-11-01 00:00:00

abstract：:The differential diagnosis of neuroendocrine neoplasms of the larynx is broad and includes lesions of epithelial, mesenchymal, and neuroectodermal origin. These lesions have overlapping clinical and pathologic aspects and must be carefully considered in the differential diagnosis of laryngeal neoplasms. The prognosis ...

journal_title：Advances in anatomic pathology

authors： Hunt JL,Ferlito A,Hellquist H,Rinaldo A,Skálová A,Slootweg PJ,Willems SM,Cardesa A

更新日期：2017-05-01 00:00:00

abstract：:Anal squamous cell carcinoma and its precursor lesions are increasing in incidence in the United States and Europe. This trend predates human immunodeficiency virus/acquired immune deficiency syndrome and has been associated with persistent high-risk human papilloma virus (HPV) genotype infection, previous lower genit...

journal_title：Advances in anatomic pathology

authors： Longacre TA,Kong CS,Welton ML

更新日期：2008-09-01 00:00:00

abstract：:The analysis of a large number of tumor tissues with conventional techniques of molecular pathology is tedious and slow. The authors recently developed the tissue microarray technology that makes it possible to sample up to 1,000 tumors on one glass slide, which then can be analyzed by fluorescence in situ hybridizati...

journal_title：Advances in anatomic pathology

authors： Moch H,Kononen T,Kallioniemi OP,Sauter G

更新日期：2001-01-01 00:00:00

abstract：:The estrogen receptor (ER) is a regulator of cellular growth, proliferation, and differentiation. In addition to having prognostic value, ER is the most important biologic marker of therapeutic response in breast cancer. Some level of measurable ER protein is expressed in 70-80% of human breast. Immunohistochemistry i...

journal_title：Advances in anatomic pathology

authors： Diaz LK,Sneige N

更新日期：2005-01-01 00:00:00

abstract：:For many pathologists, the roles of the medical director are not clearly distinguished from other medical leadership and management duties, such as those of the chair of pathology or a section head of anatomic pathology. We describe the evolution in the understanding of the roles of the medical director as defined by ...

journal_title：Advances in anatomic pathology

authors： Hernandez JS

更新日期：2011-01-01 00:00:00

abstract：:Nephropathology is a specialized field requiring routine tissue evaluation by immunofluorescence (IF), electron microscopy (EM), and light microscopy, and has published standards of best practice. Actual practices are less well documented. We therefore evaluated actual practices in nephropathology and their divergence...

journal_title：Advances in anatomic pathology

authors： Pullman JM,Ferrario F,Nast CC

更新日期：2007-03-01 00:00:00

abstract：:Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In recent years, there has been considerable progress in efforts to reveal the molecular landscape of these tumors, although it is still limited and appears to be only the tip of the iceberg. Genomic aberrations, especially specific chr...

journal_title：Advances in anatomic pathology

authors： Toper MH,Sarioglu S

更新日期：2021-01-04 00:00:00

abstract：:Dysproteinemia is a clinical state characterized by abnormal, often excessive, synthesis of immunoglobulin (Ig) molecules or subunits. Dysproteinemia results from clonal proliferation of plasma cells or B lymphocytes. The abnormal circulating Ig molecules or subunits (most commonly free light chains) reach the glomeru...

journal_title：Advances in anatomic pathology

authors： Markowitz GS

更新日期：2004-01-01 00:00:00

abstract：:This article reviews the recent dermatopathology literature regarding cutaneous adnexal neoplasms, with emphasis on new and underrecognized entities, "old entities" with new findings, advances in immunohistochemistry, and new findings in relation to inherited disorders associated with cutaneous adnexal neoplasms. ...

journal_title：Advances in anatomic pathology

authors： Ali SM,Sangueza OP

更新日期：2013-09-01 00:00:00

abstract：:Plasmacytoid dendritic cells (PDCs) have perplexed pathologists for decades, undergoing multiple adjustments in nomenclature as their lineage and functions have been characterized. Although PDCs account for less than 0.1% of peripheral blood mononuclear cells, they serve as a principal source of interferon-alpha and a...

journal_title：Advances in anatomic pathology

authors： Jegalian AG,Facchetti F,Jaffe ES

更新日期：2009-11-01 00:00:00

abstract：:Inflammatory osteolysis is a relatively frequent and incapacitating complication of rheumatoid arthritis and other inflammatory diseases, and is induced by accelerated osteoclast recruitment and activation in bone under the aegis of cytokines produced in the inflammatory environment. The success of antitumor necrosis ...

journal_title：Advances in anatomic pathology

authors： Wei S,Siegal GP

更新日期：2007-01-01 00:00:00

abstract：:The concept of Waldenstrom macroglobulinemia has evolved from the original description of a clinical syndrome to its more recent designation as a distinct clinicopathologic entity, that is, lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM), in the World Health Organization (WHO) classification and by t...

journal_title：Advances in anatomic pathology

authors： Lin P,Medeiros LJ

更新日期：2005-09-01 00:00:00

abstract：:Gastrointestinal (GI) tract tumors with melanocytic differentiation may present significant diagnostic challenges both for the pathologist and the clinician. This comprehensive review discusses the relatively common as well as rare entities that have melanocytic differentiation in the GI tract. Clinical, histologic, i...

journal_title：Advances in anatomic pathology

authors： Karamchandani DM,Patil DT,Goldblum JR

更新日期：2013-11-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a systemic, progressive, and fatal condition affecting almost exclusively women in their reproductive years. LAM most often occurs as a sporadic disease, but also occurs in women with tuberous sclerosis complex (TSC) (syndromic LAM). There are no pathologic differences between sporadi...

journal_title：Advances in anatomic pathology

authors： Bisceglia M,D'Alessandro V,Simeone A,Ben-Dor D,Pasquinelli G

更新日期：2010-11-01 00:00:00