Evaluation of a commercial measles virus immunoglobulin M enzyme immunoassay.

Abstract:

:Paired serum samples from 93 patients suspected of having measles were assayed for measles virus-specific immunoglobulin M (IgM) antibodies by an enzyme immunoassay (EIA), and the results were compared with results from a complement fixation assay and an EIA for measles virus IgG. By using significant serologic rises as the standard for comparison, the IgM EIA assay had a sensitivity of 85.7%, a specificity of 81.3%, a positive predictive value of 95.7%, and a negative predictive value of 54.2%. This assay can be expected to perform well in outbreak situations.

journal_name

J Clin Microbiol

authors

Mayo DR,Brennan T,Cormier DP,Hadler J,Lamb P

doi

10.1128/JCM.29.12.2865-2867.1991

subject

Has Abstract

pub_date

1991-12-01 00:00:00

pages

2865-7

issue

12

eissn

0095-1137

issn

1098-660X

journal_volume

29

pub_type

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