Asymptomatic bilateral adrenal pheochromocytoma in a patient with a germline V804M mutation in the RET proto-oncogene.

abstract：:A single fasting level of serum prolactin was measured in each of sixty control subjects and eighty-three psychiatric patients of both sexes who had been on neuroleptic therapy for 2-4 weeks (acute treatment) or at least 5 years (chronic treatment) and who were aged either 17-45 or 48-85 years. All groups of patients ...

journal_title：Clinical endocrinology

authors： Rivera JL,Lal S,Ettigi P,Hontela S,Muller HF,Friesen HG

更新日期：1976-05-01 00:00:00

abstract：:This study deals with serum prolactin concentrations during various conditions in the early puerperium in an attempt to investigate some characteristics of the mechanisms responsible for the regulation of the lactotropes. In nursing, in non-nursing, non-medicated and in non-nursing, bromocriptine-treated women prolact...

journal_title：Clinical endocrinology

authors： Vemer HM,Rolland R

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate symptoms of thyrotoxicosis, bone turnover, bone mineral density (BMD) and occult atrial fibrillation (AF) in women ≥65 years with mild endogenous subclinical hyperthyroidism (SCH). DESIGN:Cross-sectional and case-control study. PATIENTS:Signs and symptoms of thyro...

journal_title：Clinical endocrinology

authors： Rosario PW,Carvalho M,Calsolari MR

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:Vaspin is associated with metabolic parameters and insulin resistance. However, the expression of vaspin in visceral adipose tissue (VAT) in pregnant women with gestational diabetes mellitus (GDM) has not been fully explored, and the contribution of vaspin to the biological mechanisms underlying GDM remains u...

journal_title：Clinical endocrinology

authors： Tang Y,Qiao P,Qu X,Bao Y,Li Y,Liao Y,Ying H

更新日期：2017-10-01 00:00:00

abstract：:Six girls and one boy with precocious puberty were treated with a superactive LHRH analogue (D-TRP6-LHRH) for periods ranging from 1 year to 2 years and 3 months. In the first phase of the treatment it was administered in combination with cyproterone acetate (CyA) to counteract an early stimulatory effect until inhibi...

journal_title：Clinical endocrinology

authors： Kauli R,Pertzelan A,Ben-Zeev Z,Lewin RP,Kaufman H,Schally AM,Schally AV,Laron Z

更新日期：1984-04-01 00:00:00

abstract：:Plasma levels of LH, FSH, oestradiol 17 beta and testosterone were measured in twenty-two men with gynaecomastia. The group was divided by age into those under and those over 50-years-old and the mean hormone levels of the two groups were compared with two groups of age-matched normal men. In the young men with gynaec...

journal_title：Clinical endocrinology

authors： McFadyen IJ,Bolton AE,Cameron EH,Hunter WM,Raab G,Forrest AP

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:Nonuniformity in suppression of spermatogenesis induced by various hormones or hormone combinations has impeded the development of an effective hormonal male contraceptive. The basis for this heterogeneity in response remained unresolved to date; however, the presence of ethnic differences points to an involv...

journal_title：Clinical endocrinology

authors： Eckardstein SV,Schmidt A,Kamischke A,Simoni M,Gromoll J,Nieschlag E

更新日期：2002-11-01 00:00:00

abstract：:We have studied the inositol phospholipid turnover response to thyrotrophin-releasing hormone (TRH) gonadotrophin-releasing hormone (GnRH) and arginine vasopressin (AVP) in five corticotroph and six somatotroph pituitary adenomas. GnRH (100 nM) increased inositol phospholipid turnover in five of five somatotroph adeno...

journal_title：Clinical endocrinology

authors： Levy A,Lightman SL,Hoyland J,Mason WT

更新日期：1990-07-01 00:00:00

abstract：:The growth hormone (GH) and prolactin (PRL) responses to metoclopramide (MCP) were compared to those with arginine and insulin-induced hypoglycaemia in eight children. While a significant rise in GH release after stimulation with arginine and insulin occurred in all subjects (P less than 0.05), no significant increase...

journal_title：Clinical endocrinology

authors： Ijaiya K,Roth B,Schwenk A

更新日期：1980-06-01 00:00:00

abstract：:Pituitary-dependent Cushing's syndrome is rare in childhood. Two patients are reported who had unsuccessful transsphenoidal microadenomectomy and therefore underwent pituitary radiotherapy. In both patients there was progressive normalization of hypothalamo-pituitary-adrenal function and at 8 and 10 years after radiot...

journal_title：Clinical endocrinology

authors： Johnston LB,Grossmann AB,Plowman PN,Besser GM,Savage MO

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:Cabergoline therapy normalizes prolactin levels and reduces the size of macroprolactinomas. However there are no data indicating whether cabergoline can normalize growth hormone secretion in patients who were growth hormone deficient at the time of diagnosis of a macroprolactinoma. SUBJECTS AND METHODS:We st...

journal_title：Clinical endocrinology

authors： George LD,Nicolau N,Scanlon MF,Davies JS

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:Human GH treatment of short children who had intrauterine growth retardation (IUGR) results in a highly variable growth response. The object of this study was to test the hypothesis that differences in responsiveness to exogenously administered GH might reflect differences in endogenous GH secretion or sensit...

journal_title：Clinical endocrinology

authors： Frank GR,Cheung PT,Horn JA,Alfaro MP,Smith EP,Chernausek SD

更新日期：1996-06-01 00:00:00

abstract：CONTEXT:Anaerobic capacity is impaired in adults with GH deficiency (GHD), adversely affecting physical function and quality of life (QoL). OBJECTIVE:To investigate whether GH replacement improves anaerobic capacity, physical function and QoL in adults with GHD. DESIGN:One-month double-blind placebo-controlled crosso...

journal_title：Clinical endocrinology

authors： Chikani V,Cuneo RC,Hickman I,Ho KK

更新日期：2016-10-01 00:00:00

abstract：RATIONALE:In vitro fertilization (IVF) is a common treatment for infertility. In mice, IVF is associated with development of glucose intolerance. However, human data are limited regarding the metabolic, endocrine and inflammatory effects of IVF therapy in IVF-conceived pregnancies. OBJECTIVE:To explore effects of IVF ...

journal_title：Clinical endocrinology

authors： Coussa A,Hasan HA,Barber TM

更新日期：2020-12-01 00:00:00

abstract：:The inactivation of synthetic [3H]thyrotrophin-releasing hormone (TRH) by plasma was studied in rats treated with propylthiouracil (PTU) alone or with PTU and thyroxine. 48 h after the onset of treatment with thyroxine, the capacity of rat plasma to inactivate [3H]TRH was significantly increased. The percentage of dea...

journal_title：Clinical endocrinology

authors： Dupont A,Labrie F,Levasseur L,Dussault JH,Schally AV

更新日期：1976-07-01 00:00:00

abstract：CONTEXT:Vitamin D-dependent rickets type 1A (VDDR-IA, OMIM 264700) is a rare autosomal recessive disorder and is caused by mutations in the CYP27B1 gene. OBJECTIVES:We aim to investigate CYP27B1 mutation in seven patients from four separate families and characterize the genotype-phenotype correlation. METHODS:The ent...

journal_title：Clinical endocrinology

authors： Durmaz E,Zou M,Al-Rijjal RA,Bircan I,Akçurin S,Meyer B,Shi Y

更新日期：2012-09-01 00:00:00

abstract：:Plasma concentrations of FSH, LH, testosterone and prolactin have been studied in seventeen men, aged 19 to 38 years, with traumatic paraplegia. Plasma testosterone, FSH and LH values were normal in all patients. The median LH concentration in patients was significantly higher (P less than 0.05) than in controls but t...

journal_title：Clinical endocrinology

authors： Young RJ,Strachan RK,Seth J,Nicol K,Frier BM,Corrall RJ

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:The newly discovered vasoactive peptides, endothelin 1, 2 and 3, and their receptors are widely distributed in various non-vascular tissues. Recent studies have suggested the presence, as well as possible regulatory roles, of endothelins at several levels of the pituitary-gonadal axis. We determined the level...

journal_title：Clinical endocrinology

authors： Hammami MM,Haq A,AlSedairy S

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:There is increasing evidence that antenatal stress has long-lasting effects on child development, but there is less accord on the mechanisms and the gestational window of susceptibility. One possible mechanism is by foetal exposure to maternal cortisol. To explore this, we investigated the relationship betwee...

journal_title：Clinical endocrinology

authors： Sarkar P,Bergman K,Fisk NM,O'Connor TG,Glover V

更新日期：2007-05-01 00:00:00

abstract：:A 39-year-old woman presented with amenorrhoea, hyperprolactinaemia and sellar mass. Bromocriptine normalized PRL levels but failed to suppress tumour growth. Subsequently, she developed clinical signs and elevated blood cortisol levels consistent with a diagnosis of Cushing's disease. A pituitary tumour was removed w...

journal_title：Clinical endocrinology

authors： Ikeda H,Yoshimoto T,Kovacs K,Horvath E

更新日期：1995-09-01 00:00:00

abstract：CONTEXT:Germline mutations in four genes (RET, VHL, SDHB and SDHD) are detected in about 17% of patients with apparently sporadic pheochromocytoma. Thus, genetic screening of all patients with this disease is suggested for a rational diagnostic approach and management. OBJECTIVE:To report the clinical, biochemical and...

journal_title：Clinical endocrinology

authors： D'Elia AV,Grimaldi F,Pizzolitto S,De Maglio G,Bregant E,Passon N,Franzoni A,Verrienti A,Tamburrano G,Durante C,Filetti S,Fogolari F,Russo D,Damante G

更新日期：2013-03-01 00:00:00

abstract：:Pituitary homogenates were prepared from patients undergoing pituitary ablation for breast or prostatic carcinoma (controls) and from patients with either PRL- and GH-secreting pituitary adenomas or from patients with 'functionless' pituitary tumours. The principal subcellular organelles, plasma membrane, lysosomes, m...

journal_title：Clinical endocrinology

authors： De Marco L,Mashiter K,Peters TJ

更新日期：1984-11-01 00:00:00

abstract：:1 alpha, 25-Dihydroxycholecalciferol (1,25-(OH)2D3) has been measured in human serum by radioimmunoassay. The assay uses a high titre antiserum raised in sheep against 1,25-(OH)2D3-25-hemisuccinate, conjugated to bovine serum albumin. The sensitivity of the assay is 10 pg/tube. Other hydroxylated forms of vitamin D3 c...

journal_title：Clinical endocrinology

authors： Clemens TL,Hendy GN,Papapoulos SE,Fraher LJ,Care AD,O'Riordan JL

更新日期：1979-01-01 00:00:00

abstract：:The identification of genes placing individuals at an increased risk for the development of autoimmune thyroid disease (AITD) has been a slow process. However, over the last 20 years or so real progress has been made with the mapping of novel loci, via a number of different approaches. First, through the use of tradit...

journal_title：Clinical endocrinology

authors： Zeitlin AA,Simmonds MJ,Gough SC

更新日期：2008-05-01 00:00:00

abstract：:A 30 year old woman presenting with infertility was found to have elevated serum immunoreactive prolactin, TSH and total T3. These findings were eventually attributed to assay artifact when she was shown to have anti-rabbit antibodies in her serum. The possibility of laboratory artifact should be considered in clinica...

journal_title：Clinical endocrinology

authors： Jeffcoate WJ,Selby C,Powell RJ

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To assess possible side-effects of long-term continuous growth hormone (GH) treatment on carbohydrate (CH) metabolism in children with short stature born small for gestational age. DESIGN:In a prospective, randomised double-blind, dose-response multicentre trial, the effect of GH treatment on CH metabolism w...

journal_title：Clinical endocrinology

authors： Sas T,Mulder P,Aanstoot HJ,Houdijk M,Jansen M,Reeser M,Hokken-Koelega A

更新日期：2001-02-01 00:00:00

abstract：:The role of brain catecholamine (CA) activity in the neuroendocrine regulation of the GnRH-LH system in polycystic ovary syndrome (PCO) was investigated by high-performance liquid chromatography (HPLC) with electrochemical detector. We measured urinary dopamine (DA), noradrenaline (NA), adrenaline (A), vanillylmandeli...

journal_title：Clinical endocrinology

authors： Paradisi R,Grossi G,Venturoli S,Capelli M,Porcu E,Fabbri R,Pasquali R,Flamigni C

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:Animal studies suggest pathological foetal programming of hypothalamic circuits regulating food intake in the setting of leptin deficiency and intrauterine growth restriction (IUGR). We aimed to compare placental leptin synthesis and leptin-binding capability in venous cord blood between IUGR newborns and neo...

journal_title：Clinical endocrinology

authors： Tzschoppe A,Struwe E,Rascher W,Dörr HG,Schild RL,Goecke TW,Beckmann MW,Hofner B,Kratzsch J,Dötsch J

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Acromegalic patients have increased left ventricular (LV) mass (M) and impaired diastolic function. AIM:Using ultrasonic cardiac tissue characterization, we evaluated the early changes in cardiac fibrosis (IBS) and intrinsic myocardial contractility (CVI) as well as their reversibility after treatment with ...

journal_title：Clinical endocrinology

authors： Bogazzi F,Di Bello V,Palagi C,Donne MG,Di Cori A,Gavioli S,Talini E,Cosci C,Sardella C,Brogioni S,Mariani M,Martino E

更新日期：2005-05-01 00:00:00

abstract：:Exposure to maternal hypothyroxinemia during pregnancy, which is characterized by low free T4 but normal thyroid-stimulating hormone (TSH) levels, can negatively affect the foetus. This review provides an overview of present findings concerning the association between maternal hypothyroxinemia during pregnancy and chi...

journal_title：Clinical endocrinology

authors： Henrichs J,Ghassabian A,Peeters RP,Tiemeier H

更新日期：2013-08-01 00:00:00