Measurement of 1,25-dihydroxycholecalciferol in man by radioimmunoassay.

abstract：OBJECTIVE:The objective of this study was to evaluate symptoms of thyrotoxicosis, bone turnover, bone mineral density (BMD) and occult atrial fibrillation (AF) in women ≥65 years with mild endogenous subclinical hyperthyroidism (SCH). DESIGN:Cross-sectional and case-control study. PATIENTS:Signs and symptoms of thyro...

journal_title：Clinical endocrinology

authors： Rosario PW,Carvalho M,Calsolari MR

更新日期：2016-07-01 00:00:00

abstract：:Recombinant human TSH (rhTSH) has revolutionized the care of patients with differentiated thyroid cancer. Since its approval for clinical use in 2001 in Europe (1998 in the USA), rhTSH has greatly enhanced the surveillance of these patients by allowing the avoidance of hypothyroidism for TSH stimulation. Previously, a...

journal_title：Clinical endocrinology

authors： Woodmansee WW,Haugen BR

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Serum IGF-I levels are monitored during GH replacement treatment in adults with GH deficiency (GHD) to guide GH dose adjustment and to minimize occurrence of GH-related side-effects. This is not routine practice in children treated with GH. The aim of this study was to evaluate changes in (1) serum IGF-I, IGF...

journal_title：Clinical endocrinology

authors： Tillmann V,Patel L,Gill MS,Whatmore AJ,Price DA,Kibirige MS,Wales JK,Clayton PE

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:A GH deficiency-like phenotype with normal or high hGH secretion, pathologically low IGF-I serum levels, and catch-up growth under treatment with recombinant hGH is suggestive of the presence of biologically inactive hGH syndrome, whose presumably heterogenous molecular basis is substantially unknown. DESIG...

journal_title：Clinical endocrinology

authors： Binder G,Benz MR,Elmlinger M,Pflaum CD,Strasburger CJ,Ranke MB

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:Animal studies suggest pathological foetal programming of hypothalamic circuits regulating food intake in the setting of leptin deficiency and intrauterine growth restriction (IUGR). We aimed to compare placental leptin synthesis and leptin-binding capability in venous cord blood between IUGR newborns and neo...

journal_title：Clinical endocrinology

authors： Tzschoppe A,Struwe E,Rascher W,Dörr HG,Schild RL,Goecke TW,Beckmann MW,Hofner B,Kratzsch J,Dötsch J

更新日期：2011-04-01 00:00:00

abstract：:We have studied three patients (1M, 2F), age range 10.9 to 15.5 years, who had abnormal sexual maturation secondary to primary hypothyroidism. The boy had inappropriately large testes for his stage of puberty, the girls had isolated breast development and there was absence of pubertal growth acceleration. FSH, LH, TSH...

journal_title：Clinical endocrinology

authors： Pringle PJ,Stanhope R,Hindmarsh P,Brook CG

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome. DESIGN:Retrospective pilot study based on al...

journal_title：Clinical endocrinology

authors： Avgerinos PC,Nieman LK,Oldfield EH,Cutler GB Jr

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Malignant phaeochromocytomas are rare and highly aggressive tumours. This retrospective study evaluated the outcome of combined chemotherapy with cyclophosphamide, vincristine and dacarbazine (also known as CVD regimen). METHODS:Patients with histologically and radiologically confirmed malignant phaeochromoc...

journal_title：Clinical endocrinology

authors： Deutschbein T,Fassnacht M,Weismann D,Reincke M,Mann K,Petersenn S

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To identify predictors of hypothalamic-pituitary-adrenal (HPA) axis recovery interval and severity of glucocorticoid withdrawal symptoms (GWS) in patients undergoing adrenalectomy for corticotropin-independent cortisol excess. DESIGN:This is a retrospective study of patients with mild autonomous cortisol exc...

journal_title：Clinical endocrinology

authors： Hurtado MD,Cortes T,Natt N,Young WF Jr,Bancos I

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Pseudohypoparathyroidism type Ia (PHP-Ia) is a hereditary disorder characterized by resistance to multiple hormones that work via cAMP such as PTH and TSH, accompanied by typical skeletal features including short stature and brachydactyly, termed Albright hereditary osteodystrophy (AHO). In affected kindreds,...

journal_title：Clinical endocrinology

authors： Mouallem M,Shaharabany M,Weintrob N,Shalitin S,Nagelberg N,Shapira H,Zadik Z,Farfel Z

更新日期：2008-02-01 00:00:00

abstract：:Twenty-seven patients starting regular haemodialysis were treated with a 1 microgram daily dose of 1alpha-hydroxyvitamin D3 and concurrent aluminium hydroxide therapy to prevent hyperphosphataemia. There was an increase in plasma calcium, but no significant improvement in plasma alkaline phosphatase activity or parath...

journal_title：Clinical endocrinology

authors： Walker GS,Peacock M,Aaron J,Robinson PJ,Davison AM

更新日期：1977-12-01 00:00:00

abstract：:In 44 patients with acromegaly treated by transsphenoidal pituitary microsurgery, the relationship between changes in pre- and post-operative GH dynamics and postoperative fasting plasma GH levels was examined to clarify which is the optimal approach for evaluating postoperative removal of the tumour. TRH, LHRH and br...

journal_title：Clinical endocrinology

authors： Karashima T,Kato K,Nawata H,Ikuyama S,Ibayashi H,Nakagaki H,Kitamura K

更新日期：1986-08-01 00:00:00

abstract：:In a prospective controlled trial we investigated the effect of an induction dose of etomidate (0.26 mg/kg i.v.) on plasma ACTH, progesterone, 17 alpha OH-progesterone, 11-deoxycortisol, cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and aldosterone in seven males undergoing general anaesthesia. Seven ot...

journal_title：Clinical endocrinology

authors： Allolio B,Dörr H,Stuttmann R,Knorr D,Engelhardt D,Winkelmann W

更新日期：1985-03-01 00:00:00

abstract：:A 25-year-old primigravid woman presented with Cushing's syndrome at 23 weeks gestation; serum cortisol was 1090 nmol/l at 0900 h, 1230 nmol/l at 2200 h; basal urinary free cortisol excretion was 3680 nmol/24 h, and 8830 nmol/24 h after dexamethasone 8 mg daily for 48 hours; plasma ACTH was < 1.1 pmol/l. CT scan of th...

journal_title：Clinical endocrinology

authors： Close CF,Mann MC,Watts JF,Taylor KG

更新日期：1993-09-01 00:00:00

abstract：:Objective African-Americans have been shown to have low prevalence of hypothyroidism. Brazil has a high ethnic admixture allowing further exploration into whether environmental factors can explain the ethnic differences. Design A survey, representative of the population of Rio de Janeiro, a large metropolitan city in ...

journal_title：Clinical endocrinology

authors： Sichieri R,Baima J,Marante T,de Vasconcellos MT,Moura AS,Vaisman M

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Cranial irradiation frequently results in growth hormone (GH) deficiency. Patients with radiation-induced GH deficiency usually remain responsive to exogenous growth hormone releasing hormone, implying radiation damages the hypothalamus rather than the pituitary. Little is known about the effect of cranial ir...

journal_title：Clinical endocrinology

authors： Ogilvy-Stuart AL,Wallace WH,Shalet SM

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To estimate the frequency of the metabolic syndrome (MS) and of the insulin resistance syndrome (IRS) in overweight or obese French children and to determine the risk factors. DESIGN, PATIENTS AND METHODS:A total of 308 overweight and obese children [166 girls, 142 boys, aged 7-17 years; median body mass ind...

journal_title：Clinical endocrinology

authors： Druet C,Dabbas M,Baltakse V,Payen C,Jouret B,Baud C,Chevenne D,Ricour C,Tauber M,Polak M,Alberti C,Levy-Marchal C

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The Interleukin (IL)-10 polymorphic variants -1082G/A, -819C/T and -592C/A were linked with obesity, metabolic syndrome, and type 2 diabetes (T2DM). We investigated the hypothesis that IL-10 promoter polymorphisms may be associated with the progression of diabetic nephropathy (DN). DESIGN:Case-controlled st...

journal_title：Clinical endocrinology

authors： Ezzidi I,Mtiraoui N,Kacem M,Mallat SG,Mohamed MB,Chaieb M,Mahjoub T,Almawi WY

更新日期：2009-03-01 00:00:00

abstract：:We report an 11-year-old boy with undermasculinized genitalia and an abnormally expanded CAG repeat length at exon 1 of the androgen receptor (AR) gene. He had microphallus and scrotal hypospadias with chordee, and underwent urethroplasty at 4 years of age. At 11 years of age, a gonadotropin releasing hormone (GnRH) t...

journal_title：Clinical endocrinology

authors： Ogata T,Muroya K,Ishii T,Suzuki Y,Nakada T,Sasagawa I

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Recent evidence has shown that oxidative stress may play a role in the pathogenesis of autoimmune diseases, and this is an issue of considerable research interest in the field of infiltrative ophthalmopathy. Therefore, we evaluated both the relationship between Graves' ophthalmopathy (GO) and serum levels of...

journal_title：Clinical endocrinology

authors： Akarsu E,Buyukhatipoglu H,Aktaran S,Kurtul N

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The disruption between the brain and the spinal cord leads to a decentralized sympathetic nervous system in people with chronic, cervical spinal cord lesions. These tetraplegic subjects are prone to disorders of energy metabolism and osteoporosis, and they experience alterations in their body composition with...

journal_title：Clinical endocrinology

authors： Hjeltnes N,De Groot P,Birkeland KI,Falch JA,Iversen PO

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:The protein-tyrosine-phosphate nonreceptor 22 gene (PTPN22) has recently been identified as a susceptibility locus for a number of autoimmune diseases including Graves' disease (GD). PTPN21 is another member of the PTPN family and its gene PTPN21 maps to the first reported region of genetic linkage to GD, GD-...

journal_title：Clinical endocrinology

authors： Zeitlin AA,Heward JM,Brand OJ,Newby PR,Franklyn JA,Gough SC,Simmonds MJ

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:To explore differences in irisin concentrations between lean adolescents with PCOS and age- and body mass index (BMI)-matched controls and examine the associations of irisin with core features of the syndrome. DESIGN:Cross-sectional study. PATIENTS:Lean females with PCOS, aged 13-21 years. MEASUREMENTS:Phy...

journal_title：Clinical endocrinology

authors： Bacopoulou F,Athanasopoulos N,Efthymiou V,Mantzou A,Aravantinos L,Vlahopoulos S,Deligeoroglou E

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:A relationship between the serotoninergic and the opiatergic system in the pathogenesis of head pain is supported by several data. This study was carried out to investigate the neuroendocrine effects of sumatriptan, a specific serotonin agonist used in the treatment of migraine, on hypothalamic-pituitary-adre...

journal_title：Clinical endocrinology

authors： Facchinetti F,Nappi RE,Sances G,Fioroni L,Nappi G,Genazzani AR

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:The 2017 revised Bethesda System for Reporting Thyroid Cytopathology (BSRTC) included new malignancy rates for each category as well as new management recommendations. Here, we evaluate the malignancy rate and test performance for BSRTC categories in a middle-sized institution outside the United States (US). ...

journal_title：Clinical endocrinology

authors： Avior G,Dagan O,Shochat I,Frenkel Y,Tessler I,Meir A,Jaffe A,Cohen O

更新日期：2020-09-27 00:00:00

abstract：UNLABELLED:Objective To evaluate the effect of strontium ranelate (SR) on bone turnover markers in women with established osteoporosis previously treated with teriparatide (TPTD--recombinant human PTH 1-34). DESIGN PATIENTS: Twenty-two postmenopausal Caucasian women (aged 65.7 +/- 1.7 years) with established osteoporos...

journal_title：Clinical endocrinology

authors： Anastasilakis AD,Goulis DG,Polyzos SA,Gerou S,Ballaouri I,Efstathiadou Z,Kita M,Avramidis A

更新日期：2009-04-01 00:00:00

abstract：CONTEXT:The substitution of liothyronine (L-T3) for levothyroxine (L-T4) is commonly employed during thyroid hormone (TH) withdrawal in preparation for diagnostic and therapeutic interventions on thyroid cancer patients. Presently, only limited data are available on the L-T3 for L-T4 therapeutic substitution. Objective...

journal_title：Clinical endocrinology

authors： Celi FS,Zemskova M,Linderman JD,Babar NI,Skarulis MC,Csako G,Wesley R,Costello R,Penzak SR,Pucino F

更新日期：2010-05-01 00:00:00

abstract：:Familial Isolated Pituitary Adenomas (FIPA), an autosomal dominant disease with low penetrance is being increasingly recognized. FIPA families can be divided into two distinct groups based on genetic and phenotypic features. Patients with mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are ch...

journal_title：Clinical endocrinology

authors： Korbonits M,Storr H,Kumar AV

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Resistance to thyroid hormone (RTH) is associated with a varied clinical presentation. The cardiac effects of RTH have been described but vascular function has yet to be fully evaluated in this condition. We have measured the arterial function of those with RTH to assess any vascular changes. DESIGN:An obser...

journal_title：Clinical endocrinology

authors： Owen PJ,Chatterjee VK,John R,Halsall D,Lazarus JH

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:GH deficiency, either in children or in adults, is a clinically relevant problem. The diagnosis is based on dynamic tests of GH secretion, which are clear cut on a group basis but highly problematic for individual diagnosis. The controversy surrounding the diagnosis of GH deficiency reflects the absence of a ...

journal_title：Clinical endocrinology

authors： Micic D,Popovic V,Kendereski A,Peino R,Dieguez C,Casanueva FF

更新日期：1996-11-01 00:00:00