Abstract:
:The interferon (IFN) system is a major effector of the innate immunity that allows time for the subsequent establishment of an adaptive immune response against wide-range pathogens. The effectiveness of IFN to control initial infection requires the cooperation between several pathways induced in the target cells. Recent studies that highlight the implication of the 3'-5' exonuclease ISG20 (IFN Stimulated Gene product of 20 kDa) in the host's defenses against pathogens are summarised in this review.
journal_name
Biochimiejournal_title
Biochimieauthors
Degols G,Eldin P,Mechti Ndoi
10.1016/j.biochi.2007.03.006subject
Has Abstractpub_date
2007-06-01 00:00:00pages
831-5issue
6-7eissn
0300-9084issn
1638-6183pii
S0300-9084(07)00057-0journal_volume
89pub_type
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