Abstract:
:The synthesis of holocytochromes in plastids is a catalyzed process. Several proteins, including plastid CcsA, Ccs1, possibly CcdA and a thioredoxin, plus at least two additional Ccs factors, are required in sub-stoichiometric amounts for the conversion of apocytochromes f and c(6) to their respective holoforms. CcsA, proposed to be a heme delivery factor, and Ccs1, an apoprotein chaperone, are speculated to interact physically in vivo. The formation of holocytochrome b(6) is a multi-step pathway in which at least four, as yet unidentified, Ccb factors are required for association of the b(H) heme. The specific requirement of reduced heme for in vitro synthesis of a cytochrome b(559)-derived holo-beta(2) suggests that cytochrome b synthesis in PSII might also be catalyzed in vivo.
journal_name
Biochimiejournal_title
Biochimieauthors
Nakamoto SS,Hamel P,Merchant Sdoi
10.1016/s0300-9084(00)00605-2keywords:
subject
Has Abstractpub_date
2000-06-01 00:00:00pages
603-14issue
6-7eissn
0300-9084issn
1638-6183pii
S0300-9084(00)00605-2journal_volume
82pub_type
杂志文章,评审相关文献
BIOCHIMIE文献大全abstract::Seryl-tRNA synthetases (SerRS) covalently attach serine to cognate tRNA(Ser). Atypical SerRSs, considerably different from canonical enzymes, have been found in methanogenic archaea. A crystal structure of methanogenic-type SerRS revealed a motif within the active site (serine ordering loop; SOL), which undergoes a no...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2011.06.013
更新日期:2011-10-01 00:00:00
abstract::The distribution of fatty acids among cellular glycerophospholipids is finely regulated by the CoA-dependent acylation of lysophospholipids followed by transacylation reactions. Arachidonic acid is the fatty acid precursor of a wide family of bioactive compounds called the eicosanoids, with key roles in innate immunit...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/j.biochi.2009.11.010
更新日期:2010-06-01 00:00:00
abstract::Bacterial survive and respond to adverse changes in the environment by regulating gene transcription through two-component regulatory systems. In Salmonella Typhimurium the STM1485 gene expression is induced under low pH (4.5) during replication inside the epithelial host cell, but it is not involved in sensing or res...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2019.02.005
更新日期:2019-05-01 00:00:00
abstract::The secretome produced by cells within the bone marrow is significant to homeostasis. The bone marrow, a well-studied organ, has multiple niches with distinct roles for supporting stem cell functions. Thus, an understanding of mediators involved in the regulation of stem cells could serve as a model for clinical probl...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/j.biochi.2018.05.018
更新日期:2018-12-01 00:00:00
abstract::Epigenetic mechanisms are likely to play a role in many complex diseases, the extent of which we only beginning to understand. COPD and asthma are two respiratory diseases subject to strong environmental influences depending on underlying genetic susceptibility. Epigenetic mechanisms such as DNA methylation, histone m...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/j.biochi.2012.07.017
更新日期:2012-11-01 00:00:00
abstract::The solubilizing powers of taurocholate, taurochenodeoxycholate and tauroursodeoxycholate for monoolein and cholesterol, and the size of the bile salt-monoolein-cholesterol micelles have been determined. For the three bile salt species, the micellar size depends on the saturation with monoolein. As a result, for a giv...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(82)80492-6
更新日期:1982-04-01 00:00:00
abstract::Interferon-gamma is a key cytokine in tumor immunosurveillance. The recently described interferon-producing killer dendritic cell (IKDC), can be distinguished from other innate effectors by its ability to kill a large variety of tumor cells and to produce high amounts of interferon-gamma after encountering tumors in t...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/j.biochi.2007.04.014
更新日期:2007-06-01 00:00:00
abstract::A 3-D model of the tyrosylable tRNA-like domain of the genomic brome mosaic virus RNAs was built by computer modelling based on solution probing of the molecule with different chemical and enzymatic reagents. This model encompasses four major structural domains, including two peculiar substructures oriented perpendicu...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/0300-9084(93)90014-j
更新日期:1993-01-01 00:00:00
abstract::This paper reviews recent data on the adenylate cyclase system of the yeast Saccharomyces cerevisiae. Since the discovery of yeast adenylate cyclase mutants and the possibility of molecular biological analysis, adenylate cyclase and the subsequent steps in the cAMP cascade have become subject of intense investigation....
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/s0300-9084(85)80228-5
更新日期:1985-01-01 00:00:00
abstract::Recombinant plasmids containing head-to-tail copies of different coat-protein replacement genomes of wheat dwarf virus (WDV) were used to study the mechanism leading to the release of replicating unit-length molecules in suspension culture cells of Triticum monococcum. For plasmids bearing two complete genomes, the vi...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/0300-9084(93)90067-3
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:We evaluated the clinical relevance of microRNA-149 (miR-149) in neuroblastoma (NB) and its functional roles in regulating NB proliferation in vitro. METHODS:QRT-PCR was used to evaluate miR-149 expression in NB cell lines and primary NB tumors. Association between endogenous miR-149 expression in primary NB t...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2017.04.011
更新日期:2017-08-01 00:00:00
abstract::Parkinson's disease (PD), a neurodegenerative disorder, is characterized by a loss of dopaminergic neurons in the substantia nigra (SN) of the brain and it is well known that the pathogenesis of PD is related to a number of risk factors including oxidative stress. Antioxidant 1 (ATOX1) protein plays a crucial role in ...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2018.10.010
更新日期:2019-01-01 00:00:00
abstract::Coumarins are a group of natural compounds widely distributed in plants. Of late, coumarins and their derivatives have grabbed much attention from the pharmacological and pharmaceutical arena due to their broad range of therapeutical qualities. A coumarin derivative 4-methylesculetin (4-ME) has known to possess effect...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2013.02.014
更新日期:2013-06-01 00:00:00
abstract::The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) stains has escalated the need for developing more efficient drugs and therapeutic strategies against tuberculosis. Here we functionally annotate a secretory mycobacterial asparaginase Rv1538c (MtA) and describe its biochemical properties. MtA primarily e...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2020.12.023
更新日期:2021-01-05 00:00:00
abstract::The efficiency of oxidative phosphorylation was estimated in intact resting cells of Escherichia coli K 12, strain PA 601 (chl-s) and its chl-r mutants, all of them grown anaerobically in the presence of nitrate. The oxidation of endogenous NADH in intact chl-s cells was accompanied by the formation of ATP whatever th...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(77)80316-7
更新日期:1977-01-01 00:00:00
abstract::Using a new extended set of 13 amber suppressors in E coli, systematic amino-acid replacements were performed at positions 104(E) and 238(G) of TEM-1 beta-lactamase from PUC19. The enzyme is tolerant to most substitutions tested at position 104. Missense revertants E104K, E104S or E104Y exhibited only minor changes in...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/0300-9084(90)90073-p
更新日期:1990-06-01 00:00:00
abstract::Mouse brain myelin consists of a continuum of particles of different densities, as shown by sucrose density gradient centrifugation. In normal animals most of the material (65 per cent) is concentrated between 0.6 and 0.7 M sucrose (the maximum being found at 0.66 M sucrose, corresponding to 23 per cent). The density ...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(77)80213-7
更新日期:1977-01-01 00:00:00
abstract::Peptidase family S46 consists of two types of dipeptidyl-peptidases (DPPs), DPP7 and DPP11, which liberate dipeptides from the N-termini of polypeptides along with the penultimate hydrophobic and acidic residues, respectively. Their specificities are primarily defined by a single amino acid residue, Gly673 in DPP7 and...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2017.10.015
更新日期:2018-04-01 00:00:00
abstract::The subunit composition of the myosin molecule which is built up from 3 pairs of identical polypeptide chains (2 heavy chains and 2 pairs of light chains), gives it the appearance of having symmetric structure. This homodimeric arrangement in the molecule is in fact asymmetric in its construction as a result of the na...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/s0300-9084(81)80117-4
更新日期:1981-04-01 00:00:00
abstract::Synthesis and secretion of polysaccharides by Gram-negative bacteria are a result of a concerted action of enzymatic and channel-forming proteins localized in different compartments of the cell. The presented work comprises functional characterization of PssO protein encoded within the previously identified, chromosom...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2008.08.004
更新日期:2008-11-01 00:00:00
abstract::The mitochondria have arisen as a consequence of endosymbiosis of an ancestral α-proteobacterium with a methane-producing archae. The main function of the canonical aerobic mitochondria include ATP generation via oxidative phosphorylation, heme and phospholipid synthesis, calcium homeostasis, programmed cell death, an...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/j.biochi.2013.11.018
更新日期:2014-05-01 00:00:00
abstract::Cell-free extracts of fungal mycelia of two aflatoxin non-producing isolates of Aspergillus parasiticus (SRRC 163 and SRRC 2043) were utilized for the study of enzyme activities involved in the latter stages of aflatoxin biosynthesis. The post-microsomal fractions (105,000 x g supernatant) of both SRRC 163 and SRRC 20...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/0300-9084(88)90103-4
更新日期:1988-06-01 00:00:00
abstract::Cell-to-cell movement of Poa semilatent virus (genus Hordeivirus) in infected plants is mediated by three viral 'triple gene block' (TGB) proteins. One of those termed TGBp3 is an integral membrane protein essential for intracellular transport of other TGB proteins and viral genomic RNA to plasmodesmata. TGBp3 targeti...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2011.01.002
更新日期:2011-04-01 00:00:00
abstract::Direct demonstration of the reversible dissociation of native dimeric methionyl-tRNA synthetase from E. coli has been obtained using small angle neutron scattering and deuterated enzyme. Structural parameters of the fully deuterated dimer are very similar to the hydrogenated one. Analysis of the variations of the inte...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(85)80205-4
更新日期:1985-06-01 00:00:00
abstract::The automation of the mica surface displacement of a surface force apparatus (SFA) increases the accuracy of the intermolecular force measurements that is obtained without the presence of the experimenter. The automatic device cancels any thermal drift and the stability of the mica surfaces is optimum. The distance be...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(00)80007-3
更新日期:1998-05-01 00:00:00
abstract::To elucidate the metabolic function of mRNA polyadenylation in Escherichia coli. we searched for a polyadenylate-binding protein as a potential mediator of the function of the poly(A) moiety. Using a nitrocellulose filter-binding assay and a Northwestern blot technique, a protein in the ribosomal supernatant fraction ...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(97)82741-1
更新日期:1997-09-01 00:00:00
abstract::Simian Virus 40 (SV40) DNA replication was studied in vitro using cell free extracts prepared from SV40 infected CV1 cells. The cells were fractionated into a soluble cytoplasmic fraction and nuclei. The nuclei were lysed with high salt and used to prepare a soluble nuclear fraction. Both fractions displayed DNA polym...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/s0300-9084(76)80088-0
更新日期:1976-11-13 00:00:00
abstract::Esterases and lipases both hydrolyse ester bonds. Whereas the lipases display high activity towards the aggregated state of its substrate, the esterases typically show highest activity towards the soluble state of its substrate. We have compared the amino acid sequence, the 3D-structure as well as the pH-dependent ele...
journal_title:Biochimie
pub_type: 杂志文章,评审
doi:10.1016/s0300-9084(00)01188-3
更新日期:2000-11-01 00:00:00
abstract::The product of the sex-determining gene SRY is a member of the HMG box containing protein superfamily. The HMG box is a DNA-binding domain of about 80 amino acids shared by many proteins with diverse functions. It seems that the functions of the full length protein are restricted to the HMG box but their molecular bas...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/0300-9084(94)90033-7
更新日期:1994-01-01 00:00:00
abstract::In search for yet uncharacterized proteins involved in lipid metabolism of the chicken, we have isolated a hitherto unknown protein from the serum lipoprotein fraction with a buoyant density of ≤1.063 g/ml. Data obtained by protein microsequencing and molecular cloning of cDNA defined a 537 bp cDNA encoding a precurso...
journal_title:Biochimie
pub_type: 杂志文章
doi:10.1016/j.biochi.2013.09.005
更新日期:2013-12-01 00:00:00