Abstract:
:We compared exhaled breath condensate (EBC) and induced sputum (IS) for assessing inflammation in pulmonary diseases in patients with obstructive lung disease (n = 20), persistent cough >6 months (n = 20), interstitial lung disease (n = 25) and controls (n = 10). EBC was collected by suspending a Teflon perfluoroalkoxy tube installed in an ice-filled container and connected to a polypropylene test tube. IS was recovered after 20' inhalation of 3% saline with an ultrasonic nebulizer, and 300 cells were differentially counted in cytospin Giemsa-stained slides. H(2)0(2) was measured by a method based on oxidation of phenolsulfonphthalein (phenol red) mediated by horseradish peroxidases and H(2)0(2). Pulmonary function tests were performed by conventional methods. H(2)0(2) levels in EBC and % eosinophils in IS were significantly different between groups. A positive and significant correlation was found between % eosinophils in IS and the levels of H(2)0(2) in EBC for each group and for all patients combined.
journal_name
Inflammationjournal_title
Inflammationauthors
Fireman E,Shtark M,Priel IE,Shiner R,Mor R,Kivity S,Fireman Zdoi
10.1007/s10753-007-9020-8subject
Has Abstractpub_date
2007-04-01 00:00:00pages
44-51issue
1-2eissn
0360-3997issn
1573-2576journal_volume
30pub_type
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