Special variants of differentiated thyroid cancer: does it alter the extent of surgery versus well-differentiated thyroid cancer?


INTRODUCTION:Recently, more aggressive variants of so-called well-differentiated thyroid carcinomas have been identified such as the tall cell variant, columnar cell variant, diffuse sclerosing variant, insular carcinoma, and Hürthle cell (oncocytic, oxyphilic) carcinomas. METHODS:An evidence-based review was performed to identify the optimal treatment recommendations for these thyroid cancers of intermediate differentiation. CONCLUSIONS:Although some variation exists within the group, aggressive surgical and medical management are recommended for these neoplasias. Any such recommendations should, however, be viewed in the light of the fact that the current literature mainly consists of case reports, case series, and limited reviews. The clinical presentation, pathophysiology, diagnosis, and surgical and medical management for these thyroid cancers with intermediate differentiation are discussed.


World J Surg


World journal of surgery


Carling T,Ocal IT,Udelsman R




Has Abstract


2007-05-01 00:00:00












  • Cytoreductive surgery and intraperitoneal chemo-hyperthermia for chemo-resistant and recurrent advanced epithelial ovarian cancer: prospective study of 81 patients.

    abstract:PURPOSE:There is no standardized treatment for patients with chemo-resistant or recurrent advanced ovarian cancer. Locoregional treatments combining cytoreductive surgery and intraperitoneal chemohyperthermia (HIPEC) may improve survival for locoregional disease. PATIENTS AND METHODS:A prospective single center study ...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Cotte E,Glehen O,Mohamed F,Lamy F,Falandry C,Golfier F,Gilly FN

    更新日期:2007-09-01 00:00:00

  • Clinicopathologic characteristics and postoperative outcome in Japanese and Chinese patients with thoracic esophageal cancer.

    abstract::We evaluated the clinicopathologic findings and surgical results of 140 patients with thoracic esophageal cancer treated at Shinshu University, Japan (Shinshu group), and compared them with those from 1164 patients treated at Hebei Medical College, China (Hebei group) to determine if the two groups showed any differen...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Adachi W,Koike S,Nimura Y,Koide N,Iida F,Du XQ,Ping YM,He M,Chen LQ,Zhang MD,Zhang HL

    更新日期:1996-03-01 00:00:00

  • Fibroepithelial Lesions (FELs) of the Breast: Is Routine Excision Always Necessary?

    abstract:BACKGROUND:When needle core biopsies (NCBs) of the breast reveal fibroepithelial lesions (FELs), excision is often performed to rule out a phyllodes tumor (PT), despite low malignancy rates. Consequently, the natural history of observed FELs is not well described. We analyzed the malignancy risk in excised FELs and the...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Limberg J,Barker K,Hoda S,Simmons R,Michaels A,Marti JL

    更新日期:2020-05-01 00:00:00

  • Groin hernia repair: postherniorrhaphy pain.

    abstract::Persistent pain after hernia repair is common, although it is usually mild. In 3% of patients it is severe, however, and has significant effects on work and social activities. The purpose of this review was to examine factors that affect pain after hernia repair. Although the type of anaesthetic used, local or general...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: O'Dwyer PJ,Alani A,McConnachie A

    更新日期:2005-08-01 00:00:00

  • Parapharyngeal Metastasis of Papillary Thyroid Carcinoma.

    abstract:BACKGROUND:Nodal involvement of papillary thyroid carcinoma (PTC) commonly occurs in the paratracheal region and the internal jugular chain. Lymph node metastasis in the parapharyngeal space (PPS) is rare. In this report, we describe our experience and surgical outcomes of patients with PPS metastasis of PTC. METHODS:...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Moritani S

    更新日期:2016-02-01 00:00:00

  • The Reliability of the Pre-hospital Physical Examination of the Pelvis: A Retrospective, Multicenter Study.

    abstract:INTRODUCTION:This study assesses the incidence of missed pelvic injuries in the pre-hospital setting. METHODS:All blunt trauma patients (ISS ≥ 9) with pre-hospital suspicion of and/or radiologically proven pelvic fracture documented in the TraumaRegister DGU® (TR-DGU) of the German Trauma Society DGU (2002-2011) were ...

    journal_title:World journal of surgery

    pub_type: 杂志文章,多中心研究


    authors: Lustenberger T,Walcher F,Lefering R,Schweigkofler U,Wyen H,Marzi I,Wutzler S,TraumaRegister DGU.

    更新日期:2016-12-01 00:00:00

  • An algorithm informed by the parathyroid hormone level reduces hypocalcemic complications of thyroidectomy.

    abstract:BACKGROUND:Measurement of the parathyroid hormone (PTH) level following total thyroidectomy (TTx) may allow prediction of postoperative hypocalcemia. We present an algorithmic method of managing hypocalcemia pre-emptively, based on the PTH level 1 h after operation. MATERIALS AND METHODS:We examined 423 consecutive pa...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Wiseman JE,Mossanen M,Ituarte PH,Bath JM,Yeh MW

    更新日期:2010-03-01 00:00:00

  • Severity of Recurrent Laryngeal Nerve Injuries in Thyroid Surgery.

    abstract:BACKGROUND:Few studies in the literature have reported recovery data for different types of recurrent laryngeal nerve injuries (RLNIs). This study is the first attempt to classify RLNIs and rank them by severity. METHODS:This prospective clinical study analyzed 281 RLNIs in which a true loss of signal was identified b...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Dionigi G,Wu CW,Kim HY,Rausei S,Boni L,Chiang FY

    更新日期:2016-06-01 00:00:00

  • Risk prediction for development of pancreatic fistula using the ISGPF classification scheme.

    abstract:BACKGROUND:The International Study Group on Pancreatic Fistula (ISGPF) classification scheme has become a useful system for characterizing the clinical impact of pancreatic fistula. We sought to identify predictive factors that predispose patients to fistula, specifically those with clinical relevance (grades B/C), and...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Pratt WB,Callery MP,Vollmer CM Jr

    更新日期:2008-03-01 00:00:00

  • Impact of Preoperative Exclusive Enteral Nutrition on Postoperative Complications and Recurrence After Bowel Resection in Patients with Active Crohn's Disease.

    abstract:BACKGROUND:The impact of preoperative enteral nutrition (EN) on postoperative complications and recurrence in Crohn's disease (CD) has not been investigated to date. The purpose of the present study was to determine the effect of preoperative exclusive EN on postoperative complications and recurrence after bowel resect...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Wang H,Zuo L,Zhao J,Dong J,Li Y,Gu L,Gong J,Liu Q,Zhu W

    更新日期:2016-08-01 00:00:00

  • Iatrogenic thyrotoxicosis: causal circumstances, pathophysiology, and principles of treatment-review of the literature.

    abstract::Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis ...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: Meurisse M,Gollogly L,Degauque C,Fumal I,Defechereux T,Hamoir E

    更新日期:2000-11-01 00:00:00

  • Identification of risk factors for perioperative mortality in acute mesenteric ischemia.

    abstract:INTRODUCTION:Acute intestinal ischemia is in most cases a lethal condition with a low survival rate. Risk factors of perioperative mortality are poorly defined. The aim of this study was to define risk factors that predict an adverse outcome of acute mesenteric ischemia (AMI). METHODS:A total of 132 consecutive patien...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Acosta-Merida MA,Marchena-Gomez J,Hemmersbach-Miller M,Roque-Castellano C,Hernandez-Romero JM

    更新日期:2006-08-01 00:00:00

  • Implementation Analysis of a Perioperative Patient Safety Program in Guatemala.

    abstract:BACKGROUND:The implementation of programs to improve patient safety remains challenging in low- and middle-income countries. The goal of our study was to define the barriers and facilitators to implementation of a perioperative patient safety program in Guatemala. MATERIAL AND METHODS:We conducted semi-structured inte...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sico IP,Hall BJ,Aguilar-González A,Orozco M,Ramirez C,Baumgartner JN,Boyd D,Bolaños J,Calgua E,Lou-Meda R,Rice HE

    更新日期:2020-07-01 00:00:00

  • Prognostic factors for gastric cancer influencing clinical practice.

    abstract::Despite a slow decline in the incidence of gastric cancer over the last 90 years, we can still expect to see over 100,000 patients die of this disease each decade in England and Wales. The 5-year survival rate has not improved during this century, which is largely due to the stage at diagnosis being unchanged. There a...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: Harrison JD,Fielding JW

    更新日期:1995-07-01 00:00:00

  • Factors influencing postoperative hospital mortality and long-term survival after radical resection for stage IV gallbladder carcinoma.

    abstract::Factors influencing postoperative hospital mortality and long-term survival after radical resection of stage IV gallbladder carcinoma remain unclear. The objective of this study was to identify characteristics of patients who are good candidates in terms of surgical risk and long-term survival for radical resection of...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Kondo S,Nimura Y,Kamiya J,Nagino M,Kanai M,Uesaka K,Yuasa N,Sano T,Hayakawa N

    更新日期:2003-03-01 00:00:00

  • Tamoxifen and gallstone formation in postmenopausal breast cancer patients: retrospective cohort study.

    abstract::Tamoxifen is being used successfully in breast cancer patients as adjuvant hormonal therapy. The aim of this retrospective cohort study is to evaluate the impact of tamoxifen on gallstone formation in postmenopausal breast cancer patients. A total of 3165 patients who were treated for invasive breast cancer between 19...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Akin ML,Uluutku H,Erenoglu C,Karadag A,Gulluoglu BM,Sakar B,Celenk T

    更新日期:2003-04-01 00:00:00

  • Survey of emergency and surgical capacity in the conflict-affected regions of Sri Lanka.

    abstract:BACKGROUND:Three decades of internal conflict in the North and East of Sri Lanka have taken a toll on the health care system in that area. METHODS:We proposed to quantify the current status of capacity to deliver emergency, anesthesia, and surgical interventions in the conflict affected areas of Sri Lanka. The World H...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Taira BR,Cherian MN,Yakandawala H,Kesavan R,Samarage SM,DeSilva M

    更新日期:2010-03-01 00:00:00

  • Pancreatic Duct Holder and Mucosa Squeeze-out Technique for Duct-to-Mucosa Pancreatojejunostomy After Pancreatoduodenectomy: Propensity Score Matching Analysis.

    abstract:BACKGROUND:Duct-to-mucosa pancreatojejunostomy after pancreatoduodenectomy can be technically difficult, particularly in cases with a non-dilated pancreatic duct. We devised a novel procedure employing a pancreatic duct holder and mucosa squeeze-out technique facilitating duct-to-mucosa anastomosis. We compared the per...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sugiyama M,Suzuki Y,Nakazato T,Yokoyama M,Kogure M,Abe N

    更新日期:2016-12-01 00:00:00

  • Left Hepatectomy with Combined Resection and Reconstruction of Right Hepatic Artery for Bismuth Type I and II Perihilar Cholangiocarcinoma.

    abstract:BACKGROUND:Right hepatectomy with caudate lobectomy (RHx) is considered an appropriate procedure for Bismuth type I/II perihilar cholangiocarcinoma in terms of its anatomical and oncological aspect. However, validity of left hepatectomy with caudate lobectomy (LHx) concomitant with arterial resection and reconstruction...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sugiura T,Okamura Y,Ito T,Yamamoto Y,Ashida R,Ohgi K,Nakagawa M,Uesaka K

    更新日期:2019-03-01 00:00:00

  • Limited hepatic resection for hepatocellular carcinoma in the caudate lobe.

    abstract::The most appropriate approach to treating hepatocellular carcinoma (HCC) in the caudate lobe has not yet been determined. A series of 197 patients who had undergone curative hepatic resection for HCC were analyzed. Fifteen patients had HCC in the caudate lobe: three in the Spiegel lobe (SP), three in the caudate proce...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Ikegami T,Ezaki T,Ishida T,Aimitsu S,Fujihara M,Mori M

    更新日期:2004-07-01 00:00:00

  • Detection of asymptomatic differentiated thyroid carcinoma by neck ultrasonographic screening for familial nonmedullary thyroid carcinoma.

    abstract::Mass screening for the purpose of detecting thyroid cancer at its earliest stage may not be recommended at the present time, but screening focused on certain risk groups is advocated. Familial nonmedullary thyroid carcinoma (FNMTC) is a distinct clinical entity with a high incidence of multifocality and association wi...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Uchino S,Noguchi S,Yamashita H,Murakami T,Watanabe S,Ogawa T,Tsuno A,Shuto S

    更新日期:2004-11-01 00:00:00

  • Distal Enteral Feeding Helps Blood Sugar Control in Pancreatectomized Patients.

    abstract:BACKGROUND:The change in the route of food passage after pancreaticoduodenectomy (PD) is quite similar to the change after gastric bypass surgery; both procedures bypass the duodenum and directly connect to the distal jejunum. Moreover, both procedures result in resolution of type 2 diabetes mellitus. Therefore, more d...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Wu JM,Yang CY,Kuo TC,Lai HS,Chiang PY,Hsieh SH,Tien YW

    更新日期:2015-11-01 00:00:00

  • 10-Year Oncologic Outcomes After Laparoscopic or Open Total Mesorectal Excision for Rectal Cancer.

    abstract:BACKGROUND:Only few studies have compared laparoscopic total mesorectal excision (LTME) and open total mesorectal excision (OTME) for rectal cancer with follow-up longer than 5 years. The aim of this study was to compare 10-year oncologic outcomes after LTME and OTME for nonmetastatic rectal cancer. METHODS:We conduct...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Allaix ME,Giraudo G,Ferrarese A,Arezzo A,Rebecchi F,Morino M

    更新日期:2016-12-01 00:00:00

  • Pain management for unilateral orchidopexy in children: an effective regimen.

    abstract:BACKGROUND:The reported high incidence of 30-60% postoperative pain after an elective day surgical orchidopexy is undesirable. We evaluated the efficacy of our analgesic regimen for unilateral orchidopexy in preschool children performed as a day surgical procedure. METHODS:Between January 2004 and December 2006, 247 c...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Saeed A,Khan AR,Lee V,Aslam A,Brain J,Williams MP,Brennan L,Campbell R,Samuel M

    更新日期:2009-03-01 00:00:00

  • Congenital short colon.

    abstract::Congenital short colon (CSC) is a condition in which the colon is replaced, wholly or partially, by a dilated pouch together with anorectal malformation and a colourinary fistula. Most of the reported series have been from northern India where this malformation is frequent. This paper details the management of 108 pat...

    journal_title:World journal of surgery

    pub_type: 临床试验,杂志文章


    authors: Wakhlu AK,Wakhlu A,Pandey A,Agarwal R,Tandon RK,Kureel SN

    更新日期:1996-01-01 00:00:00

  • Optimal surgery for papillary thyroid carcinoma.

    abstract::There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: Udelsman R,Lakatos E,Ladenson P

    更新日期:1996-01-01 00:00:00

  • Liver Resection for Hepatocellular Carcinoma in Patients with Renal Dysfunction.

    abstract:BACKGROUND:The aim of this study was to evaluate the feasibility of liver resection in hepatocellular carcinoma (HCC) patients with preoperative renal dysfunction (RD). METHODS:Data from 735 patients undergoing primary liver resection for HCC between 2002 and 2014 were analyzed. Short- and long-term outcomes were comp...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Shirata C,Hasegawa K,Kokudo T,Yamashita S,Yamamoto S,Arita J,Akamatsu N,Kaneko J,Sakamoto Y,Kokudo N

    更新日期:2018-12-01 00:00:00

  • Diagnostic evaluation of achalasia: from the whalebone to the Chicago classification.

    abstract::From the earliest description of dysphagia relieved by dilatation with a whalebone in 1674 we have witnessed the evolution of esophageal function testing from the conventional manometry to the high-resolution manometry (HRM) and esophageal topography pressure plotting that have led to the revised Chicago classificatio...

    journal_title:World journal of surgery

    pub_type: 历史文章,杂志文章


    authors: Fisichella PM,Jalilvand A,Lebenthal A

    更新日期:2015-07-01 00:00:00

  • Prognostic Factors in Curative Resected Locoregional Small Intestine Neuroendocrine Neoplasms.

    abstract:BACKGROUND:Small intestinal neuroendocrine neoplasms (SI-NEN) are rare, and only about 40% of patients are diagnosed without distant metastases. Aim of the study was to identify prognostic factors in patients with potentially curative resected locoregional SI-NEN. METHODS:Patients with curative resected locoregional S...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Evers M,Rinke A,Rütz J,Ramaswamy A,Maurer E,Bartsch DK

    更新日期:2021-01-08 00:00:00

  • Postmastectomy morbidity after combination preoperative irradiation and chemotherapy for locally advanced breast cancer.

    abstract::Neoadjuvant therapy for locally advanced breast cancer improves disease control, but the complications of treatment are not well established. The aim of this study was to assess the operative morbidity in 20 consecutive patients with locally advanced, noninflammatory breast cancer treated with preoperative chemotherap...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sauter ER,Eisenberg BL,Hoffman JP,Ottery FD,Boraas MC,Goldstein LJ,Solin LJ

    更新日期:1993-03-01 00:00:00