Extensive brown tumors caused by parathyroid adenoma in an adolescent patient.

Abstract:

:Primary hyperparathyroidism is a rare endocrine disease in children and young adults. The early detection and treatment of primary hyperparathyroidism led to a marked decrease in classical bone and renal manifestations of the disease. Osteitis fibrosa cystica and brown tumors have become extremely rare clinical entities. Moreover, the skeletal involvement in primary hyperparathyroidism secondary to parathyroid adenoma is extremely rare. We report on an adolescent girl with multiple brown tumors and a history of recurrent fractures as the manifestation of primary hyperparathyroidism associated with a parathyroid adenoma. The patient's clinical presentation mimicked parathyroid carcinoma. She had a large tumor associated with marked elevation in the parathyroid hormone and serum calcium levels. Skeletal manifestations were also atypical for benign primary hyperparathyroidism, with widespread brown tumors in the patient.

journal_name

Eur J Pediatr

authors

Atabek ME,Pirgon O,Sert A,Esen HH

doi

10.1007/s00431-007-0414-2

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

117-9

issue

1

eissn

0340-6199

issn

1432-1076

journal_volume

167

pub_type

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