当前位置： SCI文献检索 > EUROPEAN JOURNAL OF PEDIATRICS期刊下所有文献 > Colostrum from healthy Brazilian women inhibits adhesion and contains IgA antibodies reactive with Shiga toxin-producing Escherichia coli.

Colostrum from healthy Brazilian women inhibits adhesion and contains IgA antibodies reactive with Shiga toxin-producing Escherichia coli.

Abstract：

UNLABELLED:Although Shiga toxin-producing Escherichia coli (STEC) has been isolated in Brazil, severe manifestations of the infection, such as haemorrhagic colitis and haemolytic-uraemic syndrome, are extremely rare in our population. Enteropathogenic Escherichia coli (EPEC) is the main aetiological agent of acute infantile diarrhoea in Brazil. There are many similarities between STEC and EPEC, such as the ability to produce attaching and effacing (A/E) lesions and some virulence-associated factors. Our aim was to investigate the presence of anti-STEC antibodies in healthy people living in an EPEC endemic area. Colostrum samples collected from 51 women living in low socio-economic conditions were analysed. Two STEC strains: O111:H- (Stx1) and O157:H7 (Stx2), and one EPEC strain (O111:H-) were used in the bacterial adhesion assays to HEp-2 cells, in the Stx1 and Stx2 cytotoxicity assays on Vero cells, in immunoblotting and in ELISA assays. All the samples strongly inhibited the adhesion of the three strains and contained SIgA antibodies reactive with antigens of EPEC O111:H-, STEC O111:H- and STEC O157:H7, mainly STEC and EPEC 94 kDa adhesin intimin. High titres of anti-LPS O111 antibodies were found in many samples. Nevertheless, the cytotoxic effect of both Stx1 and Stx2 on Vero cells was not neutralised by any sample. CONCLUSION:Our results suggest that Brazilian people may be exposed to Shiga toxin-producing Escherichia colimore frequently than previously thought or alternatively there may be a cross reactive immunity between enteropathogenic Escherichia coliand Shiga toxin-producing Escherichia coli.

journal_name

Eur J Pediatr

journal_title

European journal of pediatrics

authors

Palmeira P,Carbonare SB,Amaral JA,Tino-De-Franco M,Carneiro-Sampaio MM

doi

10.1007/s00431-004-1561-3

keywords:

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

37-43

issue

1

eissn

0340-6199

issn

1432-1076

journal_volume

164

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF PEDIATRICS文献大全
  • Osteoarticular infections due to Kingella kingae in children.

    abstract：:By the description of two cases of osteoarticular infections due to Kingella kingae in two young children we wish to draw the attention of clinicians to invasive infections due to this micro-organism. Since its biological characterization in 1976, K. kingae has been increasingly reported as a human pathogen. Most comm...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/BF02072618

    authors： Lacour M,Duarte M,Beutler A,Auckenthaler R,Suter S

    更新日期：1991-07-01 00:00:00

  • Hyponatraemia and cerebral convulsion due to short term DDAVP therapy for control of enuresis nocturna.

    abstract：UNLABELLED:Desmopressin (DDAVP) is frequently used in the treatment of primary isolated enuresis nocturna if other approaches have failed. We report a further case of hyponatraemia and cerebral convulsion due to water intoxication after intranasal DDAVP application by a 6 year-old boy with enuresis. CONCLUSION:Althoug...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02115626

    authors： Schwab M,Wenzel D,Ruder H

    更新日期：1996-01-01 00:00:00

  • Haemophilus paraphrophilus, a rare cause of intracerebral abscess in children.

    abstract：:We report on a 3-year-old boy presenting with left-sided eyelid myocloni due to an intracranial abscess harboring Haemophilus paraphrophilus. This is the first description of an intracranial infection with this pathogen in a child. ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-007-0560-6

    authors： Hoefele J,Kroener C,Berweck S,Peraud A,Grabein B,Wintergerst U,Liese J

    更新日期：2008-06-01 00:00:00

  • High-frequency oscillatory ventilation in paediatric patients with acute respiratory distress syndrome--early rescue use.

    abstract：UNLABELLED:In order to determine the response to high-frequency oscillatory ventilation (HFOV), used as an "early rescue" therapy, in a cohort of paediatric patients with acute respiratory distress syndrome (ARDS), a prospective clinical study was performed in a tertiary care paediatric intensive care unit. Ten consecu...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-004-1544-4

    authors： Ben Jaballah N,Mnif K,Bouziri A,Kazdaghli K,Belhadj S,Zouari B

    更新日期：2005-01-01 00:00:00

  • Human milk bank and personalized nutrition in the NICU: a narrative review.

    abstract：:The number of infants born preterm including extremely premature babies is rising worldwide, particularly in low- and middle-income countries, which challenge neonatologists and milk banks for the provision of the most adequate nutrition for successful infant's growth and development. The benefits of mother's own milk...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-020-03887-y

    authors： Sánchez Luna M,Martin SC,Gómez-de-Orgaz CS

    更新日期：2020-11-27 00:00:00

  • Complex regional pain syndrome involving the face following snowball injury.

    abstract：:Complex regional pain syndrome (CRPS) is a condition of unknown etiology characterized by autonomic, sensory, and motor disturbance. CRPS usually follows an injury in the affected limb, which is often trivial in nature. CRPS involving the facial region is rare, and there have been no previous descriptions in children....

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-013-2159-4

    authors： Goenka A,Aziz M,Riley P,Vassallo G

    更新日期：2014-03-01 00:00:00

  • [Generalized familial semibenign BCG infection, salmonella osteomyelitis and intestinal pseudotuberculosis--due to a familial defect of the macrophage system? (author's transl)].

    abstract：:Two siblings became very ill after BCG inoculation in the newborn period. A generalized BCG infection was assumed from the clinical symptomatology and the histological findings. Later on the boy suffered from enteric salmonellosis and osteomyelitis caused by the same organism, and as a todler he had intestinal pseudot...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00445481

    authors： Heyne K

    更新日期：1976-02-04 00:00:00

  • Phenylketonuria: treatment in adolescence and adult life.

    abstract：:In our clinic the decision on whether to continue with dietary treatment of phenylketonuria or not is left to each adolescent and adult patient after the advantages and disadvantages, as discussed in this paper, of continuing diet have been presented to them. As a result 61 of 132 patients have stopped diet or decline...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/pl00014261

    authors： Brenton DP,Tarn AC,Cabrera-Abreu JC,Lilburn M

    更新日期：1996-07-01 00:00:00

  • A digital movement in the world of inactive children: favourable outcomes of playing active video games in a pilot randomized trial.

    abstract：:This parallel randomized controlled trial was aimed to evaluate whether parameters as physical fitness, reaction times, self-perception and enjoyment levels, as well as parental and children perspectives, were affected by active video games in inactive and technologically preoccupied children. Data were collected in a...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00431-019-03457-x

    authors： Coknaz D,Mirzeoglu AD,Atasoy HI,Alkoy S,Coknaz H,Goral K

    更新日期：2019-10-01 00:00:00

  • Height, weight, body mass index and pubertal development reference values for children of Turkish origin in the Netherlands.

    abstract：UNLABELLED:The aim of this study was to provide growth and sexual maturation reference data for Turkish children living in The Netherlands. We also compared these references with the reference data of children of Dutch origin and with Turkish reference data collected in Turkey and elsewhere in Europe. Cross-sectional g...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-003-1292-x

    authors： Fredriks AM,van Buuren S,Jeurissen SE,Dekker FW,Verloove-Vanhorick SP,Wit JM

    更新日期：2003-11-01 00:00:00

  • Outcome in tall stature. Final height and psychological aspects in 220 patients with and without treatment.

    abstract：UNLABELLED:In 135 women and 85 men who initially presented for tall stature, the outcome in treated (56 women and 33 men; cases) and untreated (controls) was investigated. At the time of height prediction, cases were significantly taller (P < or = 0.03) than the controls, they had higher target heights (P < 0.001) and ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s004310050740

    authors： Binder G,Grauer ML,Wehner AV,Wehner F,Ranke MB

    更新日期：1997-12-01 00:00:00

  • Prediction of final height in boys with non-tumorous hypopituitarism.

    abstract：:The total height gain was studied in 19 adult male subjects with non-tumorous hypopituitarism after they had been treated with human growth hormone (hGH) for more than 3 years and achieved final adult height. In patients with a history of breech delivery or severe perinatal asphyxia, a high multiple correlation was fo...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00442688

    authors： Van den Broeck J,Vanderschueren-Lodeweyckx M,Eggermont E

    更新日期：1988-04-01 00:00:00

  • The quality of life in adult female patients with congenital adrenal hyperplasia: a comprehensive study of the impact of genital malformations and chronic disease on female patients life.

    abstract：:Female patients with congenital adrenal hyperplasia have been frequently studied in order to determine the impact of prenatal androgen exposure on various aspects of psychological, psychosocial and psychosexual development. There is no published study to evaluate the impact of the genital malformation, genital operati...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF02276713

    authors： Kuhnle U,Bullinger M,Schwarz HP

    更新日期：1995-09-01 00:00:00

  • Successful intravenous immunoglobulin therapy for recurrent pneumococcal otitis media in young children.

    abstract：:Serum immunoglobulin levels and naturally occurring antibody titres against Streptococcus pneumoniae were measured in seven children aged 1-1.9 years with recurrent pneumococcal acute otitis media (AOM). Three of them had low IgG2 levels. Mean antibody levels of anti-pneumococcal IgG1 and anti-pneumococcal IgG2 were s...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01958979

    authors： Ishizaka A,Sakiyama Y,Otsu M,Ozutsumi K,Matsumoto S

    更新日期：1994-03-01 00:00:00

  • Foot morphology in normal-weight, overweight, and obese schoolchildren.

    abstract：UNLABELLED:This study compared the foot morphology of Spanish schoolchildren based on their body mass index and age and analyzed whether body mass index affects the child's foot development at primary school. Cross-sectional study of 1,032 schoolchildren (497 boys and 535 girls), 6-12 years old. Height and weight were ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-013-1944-4

    authors： Jiménez-Ormeño E,Aguado X,Delgado-Abellán L,Mecerreyes L,Alegre LM

    更新日期：2013-05-01 00:00:00

  • Urethral prolapse misdiagnosed as vaginal bleeding in a premenarchal girl.

    abstract：:We report on a 10-year-old girl who was presented to the Emergency Department with a 3-day history of "vaginal bleeding", the cause of which was determined to be urethral prolapse. Urethral prolapse occurs when the urethra mucosa evaginates beyond the urethral meatus. This uncommon condition in prepubescent girls shou...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-007-0523-y

    authors： Shavit I,Solt I

    更新日期：2008-05-01 00:00:00

  • Cleidocranial dysplasia with decreased bone density and biochemical findings of hypophosphatasia.

    abstract：UNLABELLED:Cleidocranial dysplasia (CCD; MIM 119600) is an autosomal dominant skeletal dysplasia characterised by hypoplastic clavicles, patent fontanelles, short stature, tooth anomalies and other variable skeletal changes. Different mutations of the RUNX2/CBFA1 gene (MIM 600211) have been detected in patients with CC...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-002-0977-x

    authors： Morava E,Kárteszi J,Weisenbach J,Caliebe A,Mundlos S,Méhes K

    更新日期：2002-11-01 00:00:00

  • Unmasking of latent hypoparathyroidism in a child with partial DiGeorge syndrome by ethylenediaminetetraacetic acid infusion.

    abstract：:DiGeorge syndrome is a rare congenital anomaly with a wide range of clinical manifestations. This syndrome is usually associated with hypocalcaemia resulting from primary hypoparathyroidism. We report here a case of an 8-year-old boy with partial DiGeorge syndrome who presented initially with neonatal hypocalcaemia, b...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01956742

    authors： Hasegawa T,Hasegawa Y,Yokoyama T,Koto S,Asamura S,Tsuchiya Y

    更新日期：1993-04-01 00:00:00

  • The pattern of growth and growth retardation of patients with hypophosphataemic vitamin D-resistant rickets: a longitudinal study.

    abstract：:Growth in height of 16 patients (5 boys and 11 girls) with hypophosphataemic rickets (HR) was studied in a longitudinal survey. The data shortly before and during puberty were analysed on the basis of Preece Baines curves, fitted to the original data; for the analysis at the age of 5 years, the original data were used...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01959355

    authors： Steendijk R,Hauspie RC

    更新日期：1992-06-01 00:00:00

  • The 'Motorik-Modul' (MoMo): physical fitness and physical activity in German children and adolescents.

    abstract：OBJECTIVES:The aim of the 'Motorik-Modul' (MoMo Basiserhebung, www.motorik-modul.de ) was to establish prevalence measurements on physical fitness and physical activity in German children and adolescents and to identify differences between age groups and genders. A total of 4,529 children and adolescents between the ag...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-010-1391-4

    authors： Woll A,Kurth BM,Opper E,Worth A,Bös K

    更新日期：2011-09-01 00:00:00

  • Multifocal infantile hepatic hemangiomas--imaging strategy and response to treatment after propranolol and steroids including review of the literature.

    abstract：:Infantile hepatic hemangioma is the most common benign liver tumor during infancy. Prompt diagnosis and timely institution of therapy are of utmost importance. Magnetic resonance imaging (MRI) plays a key role in the correct diagnosis and monitoring of treatment. We report on a 15-week-old girl with multifocal infanti...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,评审

    doi：10.1007/s00431-011-1671-7

    authors： Bosemani T,Puttgen KB,Huisman TA,Tekes A

    更新日期：2012-07-01 00:00:00

  • The effect of vitamin K supplementation on biochemical markers of bone formation in children and adolescents with cystic fibrosis.

    abstract：INTRODUCTION:Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). OBJECTIVES:Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with C...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-006-0132-1

    authors： Nicolaidou P,Stavrinadis I,Loukou I,Papadopoulou A,Georgouli H,Douros K,Priftis KN,Gourgiotis D,Matsinos YG,Doudounakis S

    更新日期：2006-08-01 00:00:00

  • Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.

    abstract：:Chlorambucil (CHL) was used in combination with prednisolone in the treatment of nine children with frequently relapsing nephrotic syndrome. Serial electroencephalograms were obtained to evaluate CHL central nervous toxicity, before, during and after treatment with this agent. EEG abnormalities were observed in two of...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF00451963

    authors： Ichida F,Konishi T,Asada R,Yamatani M,Konda M,Tani M,Tanizawa T,Suzuki Y,Okada T,Kyotani S

    更新日期：1985-09-01 00:00:00

  • Transient neonatal hypoparathyroidism in two siblings unmasking maternal normocalcemic hyperparathyroidism.

    abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-007-0528-6

    authors： Poomthavorn P,Ongphiphadhanakul B,Mahachoklertwattana P

    更新日期：2008-04-01 00:00:00

  • Acute septicaemic acalculous cholecystitis complicated by empyema caused by Salmonella group D in a previously healthy child.

    abstract：UNLABELLED:We describe a rare case of acute acalculous cholecystitis (AC) due to Salmonella group D infection in a previously healthy child who developed gall bladder empyema and bacteraemia. Salmonella group D was recovered from blood culture, as well as cultures of stool, bile and gall bladder wall samples. The patie...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-002-1051-4

    authors： Lo WT,Wang CC,Chu ML

    更新日期：2002-11-01 00:00:00

  • Two-year outcome data suggest that less invasive surfactant administration (LISA) is safe. Results from the follow-up of the randomized controlled AMV (avoid mechanical ventilation) study.

    abstract：:Less invasive surfactant administration (LISA) is a method to deliver surfactant to spontaneously breathing premature infants via a thin catheter. Here we report the two-year outcome from the AMV (avoid mechanical ventilation) study, the first randomized controlled trial on this mode of surfactant delivery. No statist...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-020-03572-0

    authors： Herting E,Kribs A,Härtel C,von der Wense A,Weller U,Hoehn T,Vochem M,Möller J,Wieg C,Roth B,Göpel W,German Neonatal Network (GNN).

    更新日期：2020-08-01 00:00:00

  • Stimulation programs for pediatric drug research--do children really benefit?

    abstract：:Most drugs that are currently prescribed in pediatrics have not been tested in children. Pediatric drug studies are stimulated in the USA by the pediatric exclusivity provision under the Food and Drug Administration Modernization Act (FDAMA) that grants patent extensions when pediatric labeling is provided. We investi...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-006-0381-z

    authors： Boots I,Sukhai RN,Klein RH,Holl RA,Wit JM,Cohen AF,Burggraaf J

    更新日期：2007-08-01 00:00:00

  • Precocious adrenarche in children born appropriate for gestational age: is there a difference between genders?

    abstract：:We aimed to determine whether precocious adrenarche (PA) has a different impact on screening tests for metabolic issues and pubertal timing in boys and girls born appropriate for gestational age (AGA). Puberty and initial metabolic screening results of 47 girls and 23 boys with PA born AGA followed up from our outpati...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/s00431-012-1796-3

    authors： Uçar A,Saka N,Baş F,Bundak R,Günöz H,Darendeliler F

    更新日期：2012-11-01 00:00:00

  • Subcutaneous recombinant erythropoietin in preterminal renal insufficiency.

    abstract：:Recombinant human erythropoietin was given to eight children and adolescents with stable chronic renal failure in the predialysis state. The hormone was administered subcutaneously, twice weekly for 12 weeks, at a starting dose of 50 U/kg per week. The dosage was adapted every 4th week. Target haemoglobin was 10.5-11....

    journal_title：European journal of pediatrics

    pub_type： 杂志文章

    doi：10.1007/BF01959224

    authors： Van Geet C,Van Dyck M,Proesmans W

    更新日期：1994-02-01 00:00:00

  • Prospective study of the burden of rotavirus gastroenteritis in Danish children and their families.

    abstract：:This was the first study to characterize the total burden of rotavirus gastroenteritis (RVGE) at both hospital and general physician (GP) clinics in Denmark, and also the first to confirm rotavirus (RV) as the leading cause of acute gastroenteritis (GE) among children <5 years in GP clinics nationwide. Several aspects...

    journal_title：European journal of pediatrics

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00431-011-1465-y

    authors： Hoffmann T,Iturriza M,Faaborg-Andersen J,Kraaer C,Nielsen CP,Gray J,Hogh B

    更新日期：2011-12-01 00:00:00