[Generalized familial semibenign BCG infection, salmonella osteomyelitis and intestinal pseudotuberculosis--due to a familial defect of the macrophage system? (author's transl)].

Abstract:

:Two siblings became very ill after BCG inoculation in the newborn period. A generalized BCG infection was assumed from the clinical symptomatology and the histological findings. Later on the boy suffered from enteric salmonellosis and osteomyelitis caused by the same organism, and as a todler he had intestinal pseudotuberculosis. Prompt recovery took place under selective antibiotic therapy. No known immunodeficiency disease could be correlated with this familial syndrome of increased susceptibility to intracellular vital microbes. A defective function of the patients macrophage system is suspected.

journal_name

Eur J Pediatr

authors

Heyne K

doi

10.1007/BF00445481

keywords:

subject

Has Abstract

pub_date

1976-02-04 00:00:00

pages

179-89

issue

3

eissn

0340-6199

issn

1432-1076

journal_volume

121

pub_type

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