Echocardiographic assessment of hemodynamic changes in preterm neonates with shock: a prospective pragmatic cohort study.

Abstract:

:Shock is a state of circulatory dysfunction and its diagnosis is complex in neonates. Hemodynamic assessment using echocardiography has potential to guide better management regimes in neonates with shock. Objective of this study is to analyze changes in the echocardiographic parameters in preterm neonates with shock at presentation and after resolution. In this prospective pragmatic Cohort study, eligible neonates with shock were monitored for changes in echocardiographic parameters at onset of shock and after resolution of shock. Paired data analysis was done for observed changes in the parameters. Based on initial clinical parameters and echocardiographic parameters, infants were assigned into different types of shock. Data of 37 infants were analyzed for baseline clinical and echocardiographic parameters, and data of 31 infants were analyzed for the changes in the observed parameters after shock resolution. Statistically significant changes were observed in inferior vena cava collapsibility index (ICI), left ventricular end diastolic volume (LVEDV), isovolemic ventricular relaxation time (IVRT), left and right ventricular stroke volume, and ejection fraction (EF). There was no agreement between clinical and echocardiographic definitions of shock.Conclusion: We noticed shock has overlapping pathophysiologic features. Our study highlights the importance of baseline documentation of echocardiographic parameters of all infants who are at risk of shock and repeat echocardiography at onset of shock to observe the changes in ICI, LVEDV, IVRT, stroke volume, and EF. This would guide pathophysiological management of shock in neonates. What is Known: • In neonates pathophysiology of shock is overlapping. • Echocardiography can help in better understanding and management of shock. What is New: • Study gives median changes in major echocardiographic parameters in neonatal shock. • These changes can guide for selection of volume and inotropes in management.

journal_name

Eur J Pediatr

authors

Pawale D,Murki S,Kulkarni D,Vardhelli V,Sharma D,Oleti T,Kiran S,Bakhru S,Koneti NR

doi

10.1007/s00431-020-03775-5

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

1893-1899

issue

12

eissn

0340-6199

issn

1432-1076

pii

10.1007/s00431-020-03775-5

journal_volume

179

pub_type

杂志文章
  • Oral zinc sulphate as primary therapeutic intervention in a child with Wilson disease.

    abstract::An 8-year-old boy with an hepatic form of Wilson disease was treated with oral zinc sulphate as the primary and sole therapy. After 4 months, liver function had dramatically improved, and the parameters characterizing copper metabolism had also normalized. ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00441526

    authors: Milanino R,Marrella M,Moretti U,Velo GP,Deganello A,Ribezzo G,Tatò L

    更新日期:1989-06-01 00:00:00

  • Familial trisomy 9p and spinal muscular atrophy: clinical, cytogenetic and embryological findings.

    abstract::The pre- and postnatal clinical, cytogenetic and embryological findings in a family suffering from trisomy 9p and spinal muscular atrophy are presented. The clinical picture of the "trisomy 9p" -syndrome is delineated. Concurrence of autosomal aberration and spinal muscular atrophy, probably of the Werdnig-Hoffmann ty...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00443119

    authors: Tolksdorf M,Kunze J,Gross-Selbeck G,Sperling K,Wegner RD,Wieczorek V,Vogel M

    更新日期:1977-08-23 00:00:00

  • Transient and permanent neonatal diabetes.

    abstract::Neonatal diabetes, which may be transient or permanent, is rare. Most patients are full-term but small- for-date infants. Typical symptoms of diabetes mellitus occur within the first 4 weeks of life, requiring insulin therapy and very strict blood glucose monitoring. Subsequent growth and psychomotor development are u...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF01958635

    authors: Fösel S

    更新日期:1995-12-01 00:00:00

  • Outcome and survival of 88 patients with urea cycle disorders: a retrospective evaluation.

    abstract:UNLABELLED:This paper presents data obtained by questionnaires sent to local hospitals and metabolic centres in Germany, Austria, Italy and Switzerland concerning the survival and outcome of patients with urea cycle disorders treated between 1975 and 1986. A total of 130 questionnaires were sent out of which 88 questio...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-003-1188-9

    authors: Bachmann C

    更新日期:2003-06-01 00:00:00

  • Neurological complications of pandemic influenza A H1N1 2009 infection: European case series and review.

    abstract::Neurological manifestations and outcomes of children with the 2009 H1N1 virus infection have been reported in three American series and from smaller cohorts and case reports worldwide. Of the 83 children admitted between April 2009 and March 2010 with H1N1 virus infection to a tertiary children's hospital in a Europea...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00431-010-1392-3

    authors: Surana P,Tang S,McDougall M,Tong CY,Menson E,Lim M

    更新日期:2011-08-01 00:00:00

  • Thyroid function testing in neonates born to women with hypothyroidism.

    abstract::Our aim was to assess the utility of serum thyroxine and thyroid stimulating hormone performed at 10-14 days of life in diagnosing congenital hypothyroidism (CH) in babies born to mothers with hypothyroidism. This was a retrospective study of all babies born in a tertiary referral centre for neonatology over a 12-mont...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-016-2793-8

    authors: McGovern M,Reyani Z,O'Connor P,White M,Miletin J

    更新日期:2016-12-01 00:00:00

  • A milder variant of Zellweger syndrome.

    abstract::A 4.5-year-old male patient is described with chorioretinopathy, minor facial anomalies, delayed closure of the fontanel, mental retardation, moderate hypotonia, epilepsy and hepatic fibrosis. Postural control, intentional vocalising and manual dexterity were superior to the performance of patients with classical Zell...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00441774

    authors: Barth PG,Schutgens RB,Bakkeren JA,Dingemans KP,Heymans HS,Douwes AC,van der Klei-van Moorsel JM

    更新日期:1985-11-01 00:00:00

  • Partial 3-methylcrotonyl-CoA carboxylase deficiency in an infant with fatal outcome due to progressive respiratory failure.

    abstract:UNLABELLED:Isolated partial 3-methylcrotonyl-CoA carboxylase (MCC) deficiency has been described to be the cause for a distinct relatively mild clinical picture in a single patient. We describe another patient with isolated partial MCC deficiency who suffered from failure to thrive, muscular hypotonia and progressive r...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s004310050800

    authors: Wiesmann UN,Suormala T,Pfenninger J,Baumgartner ER

    更新日期:1998-03-01 00:00:00

  • A 4-month-old boy with acrodermatitis enteropathica-like symptoms.

    abstract::A 4-month-old boy was admitted for having diffuse eruption in the perianal region, legs, trunk hands, and face with failure to thrive, edema, hypoalbuminemia, and anemia. The patient was thought to have acrodermatitis enteropathica-like eruption due to malabsorption. The eruption completely resolved with enzyme supple...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-008-0825-8

    authors: Pekcan S,Kose M,Dogru D,Sekerel B,Atakan N,Ozcelik U,Cobanoglu N,Yalcin E,Kiper N

    更新日期:2009-01-01 00:00:00

  • Complex regional pain syndrome involving the face following snowball injury.

    abstract::Complex regional pain syndrome (CRPS) is a condition of unknown etiology characterized by autonomic, sensory, and motor disturbance. CRPS usually follows an injury in the affected limb, which is often trivial in nature. CRPS involving the facial region is rare, and there have been no previous descriptions in children....

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-013-2159-4

    authors: Goenka A,Aziz M,Riley P,Vassallo G

    更新日期:2014-03-01 00:00:00

  • Urethral prolapse misdiagnosed as vaginal bleeding in a premenarchal girl.

    abstract::We report on a 10-year-old girl who was presented to the Emergency Department with a 3-day history of "vaginal bleeding", the cause of which was determined to be urethral prolapse. Urethral prolapse occurs when the urethra mucosa evaginates beyond the urethral meatus. This uncommon condition in prepubescent girls shou...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-007-0523-y

    authors: Shavit I,Solt I

    更新日期:2008-05-01 00:00:00

  • Underweight problems in Asian children and adolescents.

    abstract::Most reviews on weight status have focused on obesity, and little information on underweight children is available. This review aimed to examine the prevalence and trends of underweight status among Asian children and adolescent populations in the last two decades. A systematic review of publications between the years...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00431-012-1685-9

    authors: Mak KK,Tan SH

    更新日期:2012-05-01 00:00:00

  • Perinatal COVID-19: review of current evidence and practical approach towards prevention and management.

    abstract::The clinical spectrum of the perinatal COVID-19 and prospective data on neonatal outcomes remains largely unexplored. Most of the existing literature is in the form of case series or single-centre experience. In this review, we aim to summarize available literature on the clinical spectrum of COVID-19 in neonates and ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00431-020-03866-3

    authors: Vardhelli V,Pandita A,Pillai A,Badatya SK

    更新日期:2020-11-12 00:00:00

  • De novo inv(2)(p12q34) associated with Klippel-Feil anomaly and hypodontia.

    abstract:UNLABELLED:The present case report describes a patient with Klippel-Feil anomaly (KFA) and oligodontia, carrying a de novo pericentric inversion of chromosome 2 (p12q34). KFA is characterised by congenital vertebral fusion of the cervical spine and a wide spectrum of associated anomalies. It therefore constitutes a het...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-003-1262-3

    authors: Papagrigorakis MJ,Synodinos PN,Daliouris CP,Metaxotou C

    更新日期:2003-09-01 00:00:00

  • Attitudes towards medication use in a general population of adolescents.

    abstract:UNLABELLED:Adolescents are becoming more independently responsible for their medication regimen; therefore, adolescence is a crucial period to address medication beliefs, as many of the beliefs may persist into adulthood and can impair adherence and willingness to continue a prescribed therapy. Within this study, we ai...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-013-2211-4

    authors: Koster ES,Heerdink ER,de Vries TW,Bouvy ML

    更新日期:2014-04-01 00:00:00

  • Neurophysiological findings in long-term survivors of acute lymphoblastic leukaemia in childhood treated with the BFM protocol 81 SR-A/B.

    abstract:UNLABELLED:Monitoring of therapy-related late effects after acute lymphoblastic leukaemia (ALL) therapy in childhood has become an increasingly important field in posttherapeutic patient surveillance. The usefulness of neurophysiological investigations (e.g. EEG, evoked potentials (EP)) as part of these attempts is con...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s004310050700

    authors: Ueberall MA,Skirl G,Strassburg HM,Wenzel D,Hertzberg H,Langer T,Meier W,Berger-Jones K,Huk WJ,Korinthenberg R,Beck JD

    更新日期:1997-09-01 00:00:00

  • Severe respiratory infection with Branhamella catarrhalis in an African child.

    abstract::A pure growth of Branhamella catarrhalis was obtained from a purulent bronchial exudate in a 28-month-old Rwandese girl, hospitalized for acute inspiratory dyspnoea with fever. The outcome was favourable under treatment with ampicillin, although the isolate was shown to produce a beta-lactamase in vitro. ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00442307

    authors: Bogaerts J,Lepage P,Vande Weghe JP,Vandepitte J

    更新日期:1985-03-01 00:00:00

  • Compound heterozygosity for three common MEFV mutations in a highly consanguineous family with familial Mediterranean fever.

    abstract::Consanguinity is not the only factor influencing the occurrence of autosomal recessive disorders such as familial Mediterranean fever (FMF). The extended, multiple consanguineous Turkish pedigree presented here demonstrates that the population frequency of certain mutations (so-called "ancient" mutations) can be at le...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-007-0572-2

    authors: Seidel H,Steinlein OK

    更新日期:2008-07-01 00:00:00

  • Gastric pneumatosis following cardiac surgery.

    abstract::Infiltration of the stomach wall by air, first described by Fraenkel in 1889 [3], is a very rare condition. We describe the first reported case of gastric pneumatosis occurring in a child with complex congenital heart disease after cardiac surgery. ...

    journal_title:European journal of pediatrics

    pub_type: 信件

    doi:10.1007/s004310051338

    authors: Taylor DR,Tung JY,Baffa JM,Shaffer SE,Blecker U

    更新日期:2000-07-01 00:00:00

  • Refining clinical phenotypes in septo-optic dysplasia based on MRI findings.

    abstract::Septo-optic dysplasia (SOD) is a heterogeneous brain midline anomaly associated with ophthalmological, endocrinological, and/or neurodevelopmental symptoms. The clinical phenotype correlates with abnormal brain magnetic resonance imaging (MRI) findings. However, variations of the septum pellucidum (SP) appearance and ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-007-0666-x

    authors: Riedl S,Vosahlo J,Battelino T,Stirn-Kranjc B,Brugger PC,Prayer D,Müllner-Eidenböck A,Kapelari K,Blümel P,Waldhör T,Krasny J,Lebl J,Frisch H

    更新日期:2008-11-01 00:00:00

  • Arginine-vasopressin in neonates with vasodilatory shock after cardiopulmonary bypass.

    abstract:UNLABELLED:Successful therapy of vasodilatory shock in adults and children with arginine-vasopressin (AVP) has been reported previously. Data on the use of vasopressin in neonates is limited. This retrospective study reports the effects of AVP-treatment in neonates with catecholamine-resistant systemic vasodilatation a...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-006-0400-0

    authors: Lechner E,Hofer A,Mair R,Moosbauer W,Sames-Dolzer E,Tulzer G

    更新日期:2007-12-01 00:00:00

  • Elective cesarean delivery at term and the long-term risk for respiratory morbidity of the offspring.

    abstract::Maternal morbidity is associated with cesarean deliveries. However, new evidence suggests that short- and long-term neonatal morbidity is also associated. This includes respiratory morbidity with conflicting results. To determine whether mode of delivery has an impact on the long-term risk for respiratory morbidity in...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-018-3225-8

    authors: Baumfeld Y,Walfisch A,Wainstock T,Segal I,Sergienko R,Landau D,Sheiner E

    更新日期:2018-11-01 00:00:00

  • A previously healthy 15-year-old girl with high fever and progressive dyspnoea.

    abstract::A 15-year-old girl was admitted with a high fever and progressive malaise, vomiting, anorexia and abdominal complaints. She previously had a sore throat and unilateral painful swollen lymph nodes in the neck. Laboratory investigation indicated a bacterial infection. Blood cultures were taken. There was infiltrate in t...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-007-0628-3

    authors: van Delft E,Vandewall M,Curiel FB,Rutten MJ,Schneeberger PM

    更新日期:2008-06-01 00:00:00

  • Oral vitamin A supplementation in very low birth weight neonates: a randomized controlled trial.

    abstract::This randomized double-blind placebo-controlled trial evaluated the effects of early postnatal oral vitamin A supplementation (VAS) in 196 inborn very-low birth weight (VLBW) infants requiring respiratory support at 24 h of age. Eligible infants were randomized to receive aqueous syrup of vitamin A (10,000 IU of retin...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00431-019-03412-w

    authors: Basu S,Khanna P,Srivastava R,Kumar A

    更新日期:2019-08-01 00:00:00

  • Twelve cases of tinea unguium in a pediatric clinic in 9 years.

    abstract::Tinea of the nails is not an exclusively adult pathology. The pediatrician should include this entity in the differential diagnosis. ...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-006-0332-8

    authors: Martinez Roig A,Torres Rodriguez JM

    更新日期:2007-09-01 00:00:00

  • Subcutaneous recombinant erythropoietin in preterminal renal insufficiency.

    abstract::Recombinant human erythropoietin was given to eight children and adolescents with stable chronic renal failure in the predialysis state. The hormone was administered subcutaneously, twice weekly for 12 weeks, at a starting dose of 50 U/kg per week. The dosage was adapted every 4th week. Target haemoglobin was 10.5-11....

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF01959224

    authors: Van Geet C,Van Dyck M,Proesmans W

    更新日期:1994-02-01 00:00:00

  • Comparison of two treatment eras and sonographic long-term outcome of blunt splenic injuries in children.

    abstract:UNLABELLED:The treatment of blunt splenic injuries (BSI) has undergone a significant shift away from an operative approach to a conservative treatment regimen in the last decades. Data concerning long-term follow-up of children sustaining BSI are largely confined to telephone surveys. Children treated with BSI over a 3...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-013-2022-7

    authors: Singer G,Rieder S,Eberl R,Wegmann H,Hoellwarth ME

    更新日期:2013-09-01 00:00:00

  • Neurodevelopmental outcome after prenatal exposure to opiates.

    abstract:UNLABELLED:To study the developmental effects of prenatal exposure to opiates, a prospective follow up study of 34 drug-exposed (opiates and nicotine) and 42 reference infants (nicotine exposure only) was conducted from January 1992 to September 1995. At the time of delivery, 12 of 34 mothers used opiates without medic...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s004310050923

    authors: Bunikowski R,Grimmer I,Heiser A,Metze B,Schäfer A,Obladen M

    更新日期:1998-09-01 00:00:00

  • Hypercalcaemia in cerebellar medulloblastoma: pathogenesis of solid tumour-associated hypercalcaemia.

    abstract::A 7-year-old boy developed acute, severe hypercalcaemia following the partial excision of a cerebellar medulloblastoma. The serum calcium level was extremely high (19.8 mg/100 ml), but a skeletal survey revealed no apparent bone metastatic lesions; such lesions were only detected by X-ray 3 weeks after the onset of hy...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00444958

    authors: Arisaka O,Obinata K,Yabuta K,Ishimoto K,Sato K

    更新日期:1987-07-01 00:00:00

  • Clinical spectrum of steroid sulfatase deficiency: X-linked recessive ichthyosis, birth complications and cryptorchidism.

    abstract::When boys affected with steroid sulfatase deficiency are delivered, the lack of the enzyme in the placenta may cause birth complications. In postnatal life this gene defect gives rise to X-linked recessive ichthyosis. In a series of 25 patients birth complications were reported in 9 cases. Of these boys, 4 displayed b...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00661898

    authors: Traupe H,Happle R

    更新日期:1983-03-01 00:00:00