Abstract：
UNLABELLED:In very low birth weight (VLBW) infants, colloid infusion is associated with impaired perinatal lung function and increased oxygen dependency duration. The aim of this study was to determine whether perinatal colloid infusion was associated with abnormal neurodevelopmental outcome. All perinatal fluid input (crystalloid and colloid) given to VLBW infants entered into a randomised trial was recorded. At 1 and/or 2 years, the neurodevelopmental status of VLBW infants was routinely assessed. Of 131 survivors, median gestational age 27 weeks (range 23-33 weeks), 95 were seen at follow-up. Nineteen had abnormal neurodevelopmental outcome and differed significantly from the rest of the cohort with regard to their birth weight, magnitude of colloid infusion received and the proportions who had received postnatal steroids, suffered prolonged oxygen dependency or having had intracerebral haemorrhage/periventricular leucomalacia development. Regression analysis demonstrated that only colloid infusion related significantly to abnormal neurodevelopmental outcome independent of other variables. CONCLUSION:These data suggest that colloid infusion should be used with caution in the perinatal period.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Greenough A,Cheeseman P,Kavvadia V,Dimitriou G,Morton Mdoi
10.1007/s00431-002-0950-8keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
319-23issue
6eissn
0340-6199issn
1432-1076journal_volume
161pub_type
临床试验,杂志文章,随机对照试验abstract：:Recent studies revealed that fluid overload is associated with higher mortality in critically ill children and adults. This study aimed to evaluate the association between fluid overload in the first 3 days of life and mortality in extremely low birth weight infants. This single-center retrospective cohort study inclu...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03654-z
更新日期：2020-11-01 00:00:00
abstract：:This is apparently the first report on connatal hemihypertrophy with malignant pheochromocytoma. The coincidence of hemihypertrophy with other diseases, particularly neuroectodermal dysplasias on the one hand and the frequent association of neuroectodermal dysplasias with pheochromocytoma on the other, are emphasized....
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00481506
更新日期：1976-07-12 00:00:00
abstract：:Two newborns with congenital rubella syndrome are reported. Cranial sonography demonstrated bilateral cystic lesions in the subependymal germinal matrix. Congenital rubella and cytomegalovirus (CMV) infections are the most common proven causes of subependymal cysts of nonhaemorrhagic origin in the newborn. The sonogra...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441403
更新日期：1988-12-01 00:00:00
abstract：:Four months after termination of successful chemotherapy for epipharyngeal B-non-Hodgkin lymphoma, an enlarging anterior mediastinal mass was discovered in a 15-year-old boy. There was no other suspicion of tumour recurrence. A simple thymic rebound was likely and a conservative management was chosen. Follow up for mo...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01958950
更新日期：1992-02-01 00:00:00
abstract：UNLABELLED:Over the past decade, concerns about bullying and its effects on school health have grown. However, few studies in Turkey have examined the prevalence of bullying in childhood and adolescence and its association with health problems. The current study aimed to examine the prevalence and manifestation of bull...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1782-9
更新日期：2012-10-01 00:00:00
abstract：UNLABELLED:Growth hormone (GH) secretion was determined by evaluating circadian GH profiles for 24 h and GH responses to clonidine stimulation test and insulin-stimulated hypoglycaemia (ITT), in nine prepubertal children with beta-thalassaemia major (TM) and 17 with non-GH deficient short stature (NGHDSS). The TM child...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02029352
更新日期：1995-06-01 00:00:00
abstract：:Clinical pharmacists provide beneficial services to adult patients, though their benefits for paediatric hospital patients are less defined. Five databases were searched using the MeSH terms 'clinical pharmacist', 'paediatric/paediatric', 'hospital', and 'intervention' for studies with paediatric patients conducted in...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3187-x
更新日期：2018-08-01 00:00:00
abstract：:Pediatricians' job performance, work engagement, and job satisfaction are essential for both the individual physician and quality of care for their little patients and parents. Therefore, it is important to maintain or possibly augment pediatricians' individual and professional competencies. In this study, we develope...
journal_title：European journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00431-016-2777-8
更新日期：2016-12-01 00:00:00
abstract：:The development of visual acuity and stereopsis was studied in 321 boys and 340 girls aged between 5 and 10 years. Visual acuity was assessed by the E test and a modified version of the STYCAR test, stereo acuity by the Lang-Stereo test [17]. Both vision tests showed an increase in the median visual acuity between the...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02429046
更新日期：1986-12-01 00:00:00
abstract：:A 4.5-year-old male patient is described with chorioretinopathy, minor facial anomalies, delayed closure of the fontanel, mental retardation, moderate hypotonia, epilepsy and hepatic fibrosis. Postural control, intentional vocalising and manual dexterity were superior to the performance of patients with classical Zell...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441774
更新日期：1985-11-01 00:00:00
abstract：:Extrauterine growth restriction (EUGR) is a frequent morbidity of preterm infants that can affect short- and long-term prognosis as it involves different EUGR-related alterations in growth and neurological development, as well as cardiometabolic risk. However, knowledge about the prognosis of EUGR is scarce. Thus, the...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03613-8
更新日期：2020-08-01 00:00:00
abstract：:The total height gain was studied in 19 adult male subjects with non-tumorous hypopituitarism after they had been treated with human growth hormone (hGH) for more than 3 years and achieved final adult height. In patients with a history of breech delivery or severe perinatal asphyxia, a high multiple correlation was fo...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442688
更新日期：1988-04-01 00:00:00
abstract：UNLABELLED:Cystic fibrosis is a life shortening hereditary disease, primarily leading to progressive pulmonary infection and exocrine pancreatic dysfunction. Several gastrointestinal complications other than malabsorption can arise during the disease course and with the progressively increasing life span of patients wi...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-016-2719-5
更新日期：2016-07-01 00:00:00
abstract：:The Rubinstein-Taybi syndrome is a condition characterized by mental retardation, typical facial changes and broad thumbs and big toes. The cause is unknown; almost all cases are sporadic. We describe a mother and son with Rubinstein-Taybi syndrome. Literature search documented at least 413 cases with 558 sibs. An aff...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00595907
更新日期：1989-02-01 00:00:00
abstract：INTRODUCTION:IgE-dependent activation of mast cells and basophils through the high-affinity IgE receptor (Fc(epsilon)R1) is involved in the pathogenesis of allergen-induced immune responsiveness in atopic disease including bronchial asthma. MATERIALS AND METHODS:We genotyped 650 children for allelic determinants at tw...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-009-0960-x
更新日期：2009-12-01 00:00:00
abstract：:Coeliac disease and type 1 diabetes mellitus can frequently coexist, presumably due to a common genetic predisposition. The present study was designed to evaluate the frequency of coeliac disease among Hungarian diabetic children and to study the effect of gluten-free diet on glycaemic control. A total of 205 diabetic...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1103-9
更新日期：2003-01-01 00:00:00
abstract：UNLABELLED:Monitoring of therapy-related late effects after acute lymphoblastic leukaemia (ALL) therapy in childhood has become an increasingly important field in posttherapeutic patient surveillance. The usefulness of neurophysiological investigations (e.g. EEG, evoked potentials (EP)) as part of these attempts is con...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050700
更新日期：1997-09-01 00:00:00
abstract：:Arterial hypertension in childhood is less frequent as compared to adulthood but is more likely to be secondary to an underlying disorder. After ruling out more obvious causes, some patients still present with strongly suspected secondary hypertension of yet unknown etiology. A number of these children have hypertensi...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-011-1440-7
更新日期：2012-10-01 00:00:00
abstract：:The purpose of this study was to determine the percentiles of interpopliteal distance to diagnose bowleg in 0-6 year-old children. Measurement of interpopliteal distance is a simple but valuable indicator in clinical examination to diagnose bowleg. We analyzed data from the anthropometry of Turkish children aged 0-6 y...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1414-9
更新日期：2011-09-01 00:00:00
abstract：:Brain hypoxia after cardiac arrest leads to damage of the neuronal cell membrane. Citicoline is necessary for the synthesis of cell membrane. We planned to assess the neuroprotective effect of citicoline in children after cardiac arrest. This randomized controlled trial was carried out at pediatric intensive care unit...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03871-6
更新日期：2020-11-10 00:00:00
abstract：:To find out whether cytomegalovirus (CMV) infection during the first months of life influences child development, developmental assessment at the age of 2 years was performed on 116 Finnish children chosen at random in a maternity hospital and followed from birth for the occurrence of CMV infection. Two of the childre...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496851
更新日期：1979-01-01 00:00:00
abstract：:Urinary tract infection (UTI) is a common cause of sepsis in infants. Premature infants hospitalized at a neonatal intensive care unit often have risk factors for infection. In this group, the risk of UTI is not clearly known, and guidelines for urine analysis are not unanimous. We aimed to identify the risk of UTI in...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3030-9
更新日期：2018-01-01 00:00:00
abstract：UNLABELLED:To monitor infant care practices associated with risks for sudden infant death, 400 Belgian families with infants less than 6 months old were questioned by 21 paediatricians during routine visits to local paediatric practices and well baby services (11 in urban centres, 10 in rural areas). Because of incompl...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310100783
更新日期：2001-08-01 00:00:00
abstract：:Several methods have been used for lung function testing in the ventilated newborn. The interest in the field has been stimulated by the recent appearance of commercially available equipment for assessment of mechanical parameters and of functional residual capacity in this group. Nevertheless, lung function testing i...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF02179669
更新日期：1994-01-01 00:00:00
abstract：UNLABELLED:We examined published studies from the United States, Europe, and Latin America to better understand geographic and temporal variability in the epidemiology of invasive pneumococcal disease (IPD) in young children. A comparison of IPD incidence levels reported for children <5 years of age within the United S...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1066-x
更新日期：2002-12-01 00:00:00
abstract：:A comprehensive program for proficiency testing of biochemical genetics laboratories is described. Inborn errors of metabolism of amino acids, organic acids, glycosaminoglycans and oligosaccharides are covered, as well as the assay of galactose-1-phosphate. Participants are not only required to report the analytical r...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02138772
更新日期：1994-01-01 00:00:00
abstract：:Antithyroid drugs, considered the treatment of choice for hyperthyroidism during pregnancy, may have an adverse effect on intellectual development of the offspring. We examined the intellectual capacity of 31 subjects aged 4-23 years, born to women with Graves disease who received antithyroid drugs throughout pregnanc...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01957719
更新日期：1992-08-01 00:00:00
abstract：:By November 1994, 39 pregnancies had been completed in phenylketonuric mothers. Dietary control was post-conception in 6 and 2 of these offspring died of congenital heart disease and 1 other needed surgery for coarctation. There were no heart defects in the 34 offspring of the 33 pregnancies following preconception di...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/pl00014242
更新日期：1996-07-01 00:00:00
abstract：:The aim of this study was to determine whether macrosomia related to maternal diabetes alters lipoprotein metabolism and whether these abnormalities still persist or regress after 1 month of life. Serum lipoprotein compositions and concentrations as well as serum lipid fatty acid compositions were investigated in macr...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051194
更新日期：1999-09-01 00:00:00
abstract：:Physiotherapists, occupational therapists, and speech therapists play a key role in the treatment of children with epilepsy. We performed a survey of therapists' knowledge of and attitudes towards epilepsy in two regions of Germany, the city of Leipzig and the rural district of Zwickau. Therapists of 29/68 (43%) outpa...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-019-03437-1
更新日期：2019-10-01 00:00:00
