Abstract:
:The aim of this work is to study a correlation between phenotype and genotype in clinical isolates of erythromycin-resistant Streptococcus spp. Among the 25 erythromycin-resistant S. pyogenes, we detected six strains with iMLSB, nine with cMLSB and two with M phenotypes. Among 14 erythromycin-resistant S. agalactiae, we detected five strains with iMLSB, seven with cMLSB and none with an M phenotype. Moreover, 8 S. pyogenes and 2 S. agalactiae showed a phenotype not matching the known ones described in literature, defining an unknown phenotype. Upon examination, the genetic profiles, erm(A), erm(B) and mef(A), of the clinical isolates did not easily correlate with a specific phenotype. Our findings highlighted that the whole matter of phenotypic diversity in macrolide-resistant S. pyogenes and S. agalactiae strains and the correlation with their genetic profiles should be submitted to a more careful analysis of phenotypic and genotypic characterization.
journal_name
Int J Immunopathol Pharmacolauthors
Santino I,Scazzocchio F,Berlutti F,Cipriani P,Oliva B,Paola F,Del Piano Mdoi
10.1177/039463200601900418subject
Has Abstractpub_date
2006-10-01 00:00:00pages
889-95issue
4eissn
0394-6320issn
2058-7384pii
18journal_volume
19pub_type
杂志文章abstract::In recent decades, the role played by the immune response to bacteria in the pathogenesis of chronic periodontal disease (PD) has long been studied. Although from the clinical point of view, adequate oral hygiene is essential to ensure a satisfactory response of the host to infections, modulation of the reaction of im...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738419840844
更新日期:2019-01-01 00:00:00
abstract::This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420974888
更新日期:2020-01-01 00:00:00
abstract::Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420929442
更新日期:2020-01-01 00:00:00
abstract::MicroRNAs (miRNAs) exhibit a crucial role in the regulation of angiogenesis and tumor progression, of which miR-199a-5p (miR-199a) has been reported to function as a tumor suppressor in multiple malignancies. However, the precise mechanisms underlying miR-199a in hemangiomas (HAs) remain elusive. In this study, we fou...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/0394632017749357
更新日期:2018-01-01 00:00:00
abstract::Since the introduction of the cytological screening programs, a significant reduction in the incidence of cervical cancer has been achieved. Almost all of these cancers are related to high-risk (HR) Human Papillomavirus (HPV) cervical infections. However, the natural history of HPV infection seems to be different in y...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201102400219
更新日期:2011-04-01 00:00:00
abstract::Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...
journal_title:International journal of immunopathology and pharmacology
pub_type: 临床试验,信件
doi:10.1177/039463201302600127
更新日期:2013-01-01 00:00:00
abstract::Information about the impacts of disasters on health is useful for establishing hazard prediction maps and action plans of disaster management. This study aims at learning effective asthma management from the volcano disaster of Mount Asama eruption in Japan on September 1, 2004. We conducted a cross-sectional study t...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/03946320070200S203
更新日期:2007-04-01 00:00:00
abstract::Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,评审
doi:
更新日期:2010-01-01 00:00:00
abstract::The risk and benefit of oral immunomodulation using heat-killed Enterococcus faecalis FK-23 preparation (FK-23) were evaluated in healthy dogs. Dogs were administered perorally 100 mg/kg of FK23 daily for 3 months. FK-23 did not affect the findings of complete blood count, leukocyte differential count, blood chemistry...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::Immunosuppressive treatment has changed the prognosis of Lupus nephritis over time, but improvement in prognosis is difficult to analyze in different historical periods, and should be better demonstrated in comparison with life expectancy of sex-and age-matched people. Long-term patient and renal survival of 90 patien...
journal_title:International journal of immunopathology and pharmacology
pub_type: 信件
doi:10.1177/039463200902200432
更新日期:2009-10-01 00:00:00
abstract::Some studies in animal models showed that several neurotrophins may be implicated in the regulation of light-dependent suprachiasmatic pacemaker and in other functions implicated in long-term memory acquisition during sleep. However, no data are known about the role played by NGF in ultradian regulation in humans. The...
journal_title:International journal of immunopathology and pharmacology
pub_type: 临床试验,杂志文章
doi:10.1177/039463200401700316
更新日期:2004-09-01 00:00:00
abstract::The role of inhaled corticosteroids in asthma exacerbation is debated. We compared high doses of nebulized budesonide versus high doses of nebulized flunisolide, in association with a short-acting beta-2-agonist, in the treatment of moderate asthma exacerbation in preschool children. In this randomized, parallel group...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1177/039463200902200213
更新日期:2009-04-01 00:00:00
abstract::Interleukin (IL)-8 is a major factor in inflammatory response and the IL-8 levels in exhaled breath condensate (EBC) may be used as a marker of airway inflammation. Airway acidification is implicated in the pathophysiology of obstructive airway diseases and pH EBC values have been used as a marker of airway acidificat...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200702000305
更新日期:2007-07-01 00:00:00
abstract::Capsular contracture is a highly distressing, difficult complication after breast augmentation for both the patient and the surgeon. Although capsular contracture is a multifactorial process, one common denominator in the successful treatment of this complication is believed to be the abatement of inflammation. Leukot...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1177/039463200702000315
更新日期:2007-07-01 00:00:00
abstract::To investigate the in vivo role of caspase-3 in Terminal Transferase metabolism DMSO-treated RPMI-8402, a human pre-T cell line was used. In DMSO treated samples (3)H-dGTP incorporation and TdT phosphorylation occurs after 4 hours of treatment. After 8 hours cells undergo TdT proteolysis in addition to its inactivatio...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200201500306
更新日期:2002-09-01 00:00:00
abstract::Orofacial clefts are common congenital defects whose prevalence differs between geographical regions and ethnic groups. The inheritance is complex, involving the contribution of both genetic and environmental factors. The involvement of genes belonging to the folate pathway is still matter of debate, with strong evide...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738419855571
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/2058738420950584
更新日期:2020-01-01 00:00:00
abstract::Extranodal non-Hodgkin lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The most common site of development of primary laryngeal lymphomas is the supraglottic region. In most cases, the presenting symptoms are hoarseness, dysphagia, dyspnea, and cervical lymphadenopathy...
journal_title:International journal of immunopathology and pharmacology
pub_type: 信件
doi:10.1177/039463201402700319
更新日期:2014-07-01 00:00:00
abstract::The present study investigated the sources of discomfort and the symptoms reported by earthquake victims residing in temporary emergency prefabricated accommodation (prefab). The investigation was carried out by means of a questionnaire. 203 prefab occupants and 13 inhabitants of houses, who were chosen as reference p...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/03946320040170S217
更新日期:2004-05-01 00:00:00
abstract::The possibility of the non-parenteral Hepatitis C Virus (HCV) transmission is supported by the demonstration that the actual virus is present in several body fluids, including saliva. From a review of the literature many investigators have found the presence of HCV-RNA in saliva, however, widely contrasting results em...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Optimal management of deep infections in orthopedic and trauma surgery is often challenging. Traditional prophylactic and treatment approaches are based on the systemic administration of relatively high doses of antibiotics, which may result in a number of side effects. Furthermore, systemically administered antimicro...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,多中心研究,评审
doi:10.1177/03946320110241S223
更新日期:2011-01-01 00:00:00
abstract::Human coronary artery endothelial cells (HCAEC 5156) were cultured as monolayers and exposed to concentrations of lead (as acetate, Pb) in the culture medium similar or lower than those commonly found in the blood of human beings occupationally or environmentally exposed to this element. Only at the concentration of 2...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/03946320040170S207
更新日期:2004-05-01 00:00:00
abstract::Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201202500208
更新日期:2012-04-01 00:00:00
abstract::Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its s...
journal_title:International journal of immunopathology and pharmacology
pub_type: 社论
doi:10.1177/039463201002300304
更新日期:2010-07-01 00:00:00
abstract::Oxidative stress (OS) is well documented in asthma, but so far, little data has been reported in nonasthmatic patients with Seasonal Allergic Rhinitis (SAR). The aim of this study is to investigate the degree of OS and airway inflammation in patients with SAR, with and without concomitant asthma (SAR+A), using breath ...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200802100419
更新日期:2008-10-01 00:00:00
abstract::Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...
journal_title:International journal of immunopathology and pharmacology
pub_type: 信件
doi:10.1177/039463201102400325
更新日期:2011-07-01 00:00:00
abstract::A decrease in cholesterol blood level, not due to a decrease synthesis by the liver, has been observed in patients suffering from tumors. In this work cholesterol blood was evaluated in patients affected by monoclonal gammopathy who were not subjected to any treatment. The blood of 25 patients were analyzed for protei...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463200601900210
更新日期:2006-04-01 00:00:00
abstract::Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章
doi:10.1177/039463201402700109
更新日期:2014-01-01 00:00:00
abstract::Antibiotic abuse for treating rhinopharyngitis induces the occurrence of resistant bacteria. As topical drugs might reduce this phenomenon, the aims of our study are to evaluate inhaled thiamphenicol associated with acetylcysteine in children with acute bacterial rhinopharyngitis and to compare it with the use of sali...
journal_title:International journal of immunopathology and pharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1177/039463200802100316
更新日期:2008-07-01 00:00:00
abstract::To assess the rate of sexual distress, sexual dysfunction and relationship quality and their association with clinical variables in women with systemic sclerosis (SSc), 102 sexually active women with SSc were recruited. Sexual distress, sexual dysfunction and dissatisfaction with relationship quality were investigated...
journal_title:International journal of immunopathology and pharmacology
pub_type: 信件
doi:10.1177/039463201402700216
更新日期:2014-04-01 00:00:00