Laparoscopic augmentation cystoplasty: a comparison between native ileum and small intestinal submucosa in the porcine model.


OBJECTIVES:To determine the feasibility of laparoscopic augmentation cystoplasty (LAC) in the porcine model and to compare LAC using standard bowel vs a small intestinal submucosa (SIS) allograft. MATERIALS AND METHODS:Fourteen female pigs underwent LAC; six had standard ileal AC and eight AC with SIS. All the pigs had limited cystometrogram studies before surgery to determine bladder capacity. At 6 weeks after surgery the pigs were anaesthetized, the bladder capacities were re-assessed and then the pigs were killed; the bladders were harvested and examined histologically. RESULTS:In all, 12 of 14 pigs completed the 6-week survival period; two pigs from the SIS group died from urinary ascites secondary to anastomotic leaks at the cystoplasty site. There were no complications in the ileal augmentation group. The operative duration was similar in both groups. The bladder capacities increased significantly in both groups, although more reliably in the native ileum group. In two pigs in the SIS group there was no increase in bladder capacity. CONCLUSIONS:LAC is feasible in the porcine model and results in a significant increase in bladder capacity. AC using SIS does not appear to increase bladder capacity as reliably as native ileum, and has a higher complication rate.




BJU international


Wang DS,Anderson DA,Fretz PC,Nguyen TT,Winfield HN




Has Abstract


2007-03-01 00:00:00














  • Bacillus Calmette-Guérin cell-wall skeleton enhances the killing activity of cytotoxic lymphocyte-activated human dendritic cells transduced with the prostate-specific antigen gene.

    abstract:UNLABELLED:To determine whether dendritic cells (DC) transduced with the prostate-specific antigen (PSA) gene can induce PSA-specific cytotoxic lymphocytes (CTL) against prostate cancer cells, and whether bacillus Calmette-Guérin (BCG) cell-wall skeleton (CWS) can enhance the maturation of DC-PSA and the killing activi...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Fujii R,Iwahashi M,Kikkawa K,Inagaki T,Kohjimoto Y,Ojima T,Mori T,Kuramoto T,Nishizawa S,Azuma I,Yamaue H,Shinka T,Hara I

    更新日期:2009-12-01 00:00:00

  • Robotic and laparoscopic partial nephrectomy: a matched-pair comparison from a high-volume centre.

    abstract:OBJECTIVES:To evaluate the relative merits of robotically assisted partial nephrectomy (RPN), using a matched-pair analysis, with laparoscopic PN (LPN). PATIENTS AND METHODS:Between July 2006 and August 2007, 12 patients had RPN for tumour; the outcomes were compared retrospectively with 12 matched patients who had LP...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Aron M,Koenig P,Kaouk JH,Nguyen MM,Desai MM,Gill IS

    更新日期:2008-07-01 00:00:00

  • Resistive index: an experimental study of the effects of diuretic stimulation in the unobstructed porcine kidney.

    abstract:OBJECTIVE:To study the effects of diuretic stimulation with frusemide and mannitol on the renal resistive index (RI) of the undilated unobstructed porcine kidney. MATERIALS AND METHODS:Experiments were carried out on 14 pigs divided into two equal groups (A and B), under general anaesthesia. In all pigs both ureters w...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Rawashdeh YF,Hørlyck A,Djurhuus JC,Frokiaer J,Mortensen J

    更新日期:2002-03-01 00:00:00

  • Triple incision to treat phimosis in children: an alternative to circumcision?

    abstract:OBJECTIVE:To evaluate the functional and cosmetic results and patient satisfaction after triple incision plasty for phimosis in children. PATIENTS AND METHODS:The study included 197 boys who had a triple incision for phimosis (mean age 5.8 years, range 0.25-18). The indications for preputial surgery were recurrent bal...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Fischer-Klein Ch,Rauchenwald M

    更新日期:2003-09-01 00:00:00

  • A core outcome set for localised prostate cancer effectiveness trials.

    abstract:OBJECTIVE:To develop a core outcome set (COS) applicable for effectiveness trials of all interventions for localised prostate cancer. Many treatments exist for localised prostate cancer, although it is unclear which offers the optimal therapeutic ratio; which is confounded by inconsistencies in the selection, definitio...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: MacLennan S,Williamson PR,Bekema H,Campbell M,Ramsay C,N'Dow J,MacLennan S,Vale L,Dahm P,Mottet N,Lam T,COMPACTERS Study Group.

    更新日期:2017-11-01 00:00:00

  • Does information provided to men before a urodynamic study affect their expectation of pain?

    abstract:OBJECTIVE:To evaluate the effect of a routine explanation provided to men on their expectation of pain associated with a urodynamic study (UDS). PATIENTS AND METHODS:The purpose of UDS is to reproduce patient's symptoms during the urine storage and voiding phases, and thus understand the causes of the patient's sympto...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Greenstein A,Bar-Yosef Y,Chen J,Matzkin H

    更新日期:2005-12-01 00:00:00

  • The natural history of metastatic progression in men with prostate-specific antigen recurrence after radical prostatectomy: long-term follow-up.

    abstract:OBJECTIVE:To describe metastasis-free survival (MFS) in men with prostate-specific antigen (PSA) recurrence following radical prostatectomy, and to define clinical prognostic factors modifying metastatic risk. PATIENTS AND METHODS:We conducted a retrospective analysis of 450 men treated with prostatectomy at a tertiar...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Antonarakis ES,Feng Z,Trock BJ,Humphreys EB,Carducci MA,Partin AW,Walsh PC,Eisenberger MA

    更新日期:2012-01-01 00:00:00

  • Electrolysis - a new method of renal ablation?

    abstract:OBJECTIVE:• To present a novel method of renal ablation using direct current electrolysis, using a porcine model to assess the safety and efficacy of the technique. MATERIALS AND METHODS:• In all, 20 anaesthetised pigs were used, after receiving ethical approval. The pigs were housed and managed in accordance with Ins...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Lloyd M,Miller J,Moretti KL,Texler M,Maddern GJ

    更新日期:2012-12-01 00:00:00

  • A meta-analysis comparing trials of antimuscarinic medications funded by industry or not.

    abstract:OBJECTIVE:To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA). METHODS:A Medline search was conducted from January 1966 to June 2003 to identify human cli...

    journal_title:BJU international

    pub_type: 杂志文章,meta分析,评审


    authors: Tulikangas PK,Ayers A,O'Sullivan DM

    更新日期:2006-08-01 00:00:00

  • Robot-assisted radical cystectomy: intermediate survival results at a mean follow-up of 25 months.

    abstract:OBJECTIVE:To assess the overall and disease-specific survival rates of patients undergoing robot-assisted radical cystectomy (RARC) compared with historical open cystectomy. PATIENTS AND METHODS:Survival, pathological and demographic data were collected on all patients undergoing RARC for bladder cancer from both Tula...

    journal_title:BJU international

    pub_type: 杂志文章,多中心研究


    authors: Martin AD,Nunez RN,Pacelli A,Woods ME,Davis R,Thomas R,Andrews PE,Castle EP

    更新日期:2010-06-01 00:00:00

  • Surveillance for bladder cancer: the management of 4.8 million people. South-west Urologists.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Wright MP,Jones DJ

    更新日期:2000-03-01 00:00:00

  • Gene expression profiling of renal cell carcinoma: a DNA macroarray analysis.

    abstract:OBJECTIVE:To examine differences in gene expression levels between renal cell carcinoma (RCC) tissue and 'normal' appearing renal tissue using a commercially available DNA macroarray. MATERIALS AND METHODS:Tissue was obtained from 47 consecutive radical nephrectomies, 29 of which were eligible. DNA macroarrays were an...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Lovisolo JA,Casati B,Clerici L,Marafante E,Bono AV,Celato N,Salvadore M

    更新日期:2006-07-01 00:00:00

  • Improved quality of life in patients with overactive bladder symptoms treated with solifenacin.

    abstract:OBJECTIVE:To assess the effect of solifenacin succinate treatment on quality of life (QoL) measured in clinical trials in patients with overactive bladder (OAB). PATIENTS AND METHODS:QoL data using the King's Health Questionnaire (KHQ) were analysed from two phase-3, 12-week studies (1984 patients) and a long-term ext...

    journal_title:BJU international

    pub_type: 杂志文章,meta分析


    authors: Kelleher CJ,Cardozo L,Chapple CR,Haab F,Ridder AM

    更新日期:2005-01-01 00:00:00

  • Cost-effectiveness analysis of degarelix for advanced hormone-dependent prostate cancer.

    abstract:OBJECTIVE:To evaluate the cost-effectiveness of degarelix vs luteinizing hormone-releasing hormone analogue (triptorelin) plus short-term antiandrogen treatment for advanced prostate cancer. METHODS:We developed a decision analytic model based on a clinical trial and literature review. The two interventions evaluated ...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Lu L,Peters J,Roome C,Stein K

    更新日期:2012-04-01 00:00:00

  • Can one blood draw replace transrectal ultrasonography-estimated prostate volume to predict prostate cancer risk?

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    journal_title:BJU international

    pub_type: 杂志文章,多中心研究,随机对照试验


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    更新日期:2013-09-01 00:00:00

  • Does obesity affect the accuracy of prostate-specific antigen (PSA) for predicting prostate cancer among men undergoing prostate biopsy.

    abstract:UNLABELLED:What's known on the subject? and what does the study add?: As most urologist known, obesity significantly lowers serum PSA levels. So there is some concern about delayed diagnosis of prostate cancer in obese men. In the present study, we found that the accuracy level of PSA for detecting prostate cancer was ...

    journal_title:BJU international

    pub_type: 杂志文章


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    更新日期:2013-08-01 00:00:00

  • A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladder.

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    journal_title:BJU international

    pub_type: 杂志文章,meta分析


    authors: Chapple C,Steers W,Norton P,Millard R,Kralidis G,Glavind K,Abrams P

    更新日期:2005-05-01 00:00:00

  • Emphysematous cystitis: a review of 135 cases.

    abstract:OBJECTIVE:To review recently published data on emphysematous cystitis (EC), a potentially life-threatening condition characterized by air within the bladder wall, and that most typically affects middle-aged diabetic women. METHODS:All articles published in English between 1956 and 2006 were identified using a Medline ...

    journal_title:BJU international

    pub_type: 杂志文章,评审


    authors: Thomas AA,Lane BR,Thomas AZ,Remer EM,Campbell SC,Shoskes DA

    更新日期:2007-07-01 00:00:00

  • Increased vascular endothelial growth factor expression in patients with bladder pain syndrome/interstitial cystitis: its association with pain severity and glomerulations.

    abstract:OBJECTIVE:To determine the angiogenic profiles in the bladder of patients with bladder pain syndrome (BPS)/interstitial cystitis (IC), and to evaluate the relationship between these profiles and associated clinical features including pelvic pain and glomerulations. PATIENTS AND METHODS:Angiogenesis and angiogenic comp...

    journal_title:BJU international

    pub_type: 杂志文章


    authors: Kiuchi H,Tsujimura A,Takao T,Yamamoto K,Nakayama J,Miyagawa Y,Nonomura N,Takeyama M,Okuyama A

    更新日期:2009-09-01 00:00:00

  • Contemporaneous comparison of open vs minimally-invasive radical prostatectomy for high-risk prostate cancer.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Pierorazio PM,Mullins JK,Eifler JB,Voth K,Hyams ES,Han M,Pavlovich CP,Bivalacqua TJ,Partin AW,Allaf ME,Schaeffer EM

    更新日期:2013-10-01 00:00:00

  • Renal cell carcinoma may adapt to and overcome anti-angiogenic intervention with thalidomide.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Douglas ML,Reid JL,Hii SI,Jonsson JR,Nicol DL

    更新日期:2002-04-01 00:00:00

  • Effect of low dose-rate prostate brachytherapy on the sexual health of men with optimal sexual function before treatment: analysis at > or = 7 years of follow-up.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Cesaretti JA,Kao J,Stone NN,Stock RG

    更新日期:2007-08-01 00:00:00

  • Decision curve analysis assessing the clinical benefit of NMP22 in the detection of bladder cancer: secondary analysis of a prospective trial.

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    journal_title:BJU international

    pub_type: 杂志文章,多中心研究


    authors: Barbieri CE,Cha EK,Chromecki TF,Dunning A,Lotan Y,Svatek RS,Scherr DS,Karakiewicz PI,Sun M,Mazumdar M,Shariat SF

    更新日期:2012-03-01 00:00:00

  • Damage to the bladder neck alters autonomous activity and its sensitivity to cholinergic agonists.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: de Jongh R,van Koeveringe GA,van Kerrebroeck PE,Markerink-van Ittersum M,de Vente J,Gillespie JI

    更新日期:2007-10-01 00:00:00

  • Long-term incidence of secondary bladder and rectal cancer in patients treated with brachytherapy for localized prostate cancer: a large-scale population-based analysis.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Mazzone E,Mistretta FA,Knipper S,Palumbo C,Tian Z,Pecoraro A,Preisser F,Gallina A,Shariat SF,Saad F,Graefen M,Montorsi F,Briganti A,Karakiewicz PI

    更新日期:2019-12-01 00:00:00

  • Nocturia in the Dutch adult population.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: van Dijk L,Kooij DG,Schellevis FG

    更新日期:2002-11-01 00:00:00

  • Contrast-enhanced ultrasonography with contrast-tuned imaging technology for the detection of prostate cancer: comparison with conventional ultrasonography.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Xie SW,Li HL,Du J,Xia JG,Guo YF,Xin M,Li FH

    更新日期:2012-06-01 00:00:00

  • p53, p21 and mdm2 expression vs the response to radiotherapy in transitional cell carcinoma of the bladder.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Røtterud R,Berner A,Holm R,Skovlund E,Fosså SD

    更新日期:2001-08-01 00:00:00

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    journal_title:BJU international

    pub_type: 杂志文章,评审


    authors: Margulis V,Lotan Y,Montorsi F,Shariat SF

    更新日期:2008-07-01 00:00:00

  • Performance Improvement (Pi) score: an algorithm to score Pi objectively during E-BLUS hands-on training sessions. A European Association of Urology, Section of Uro-Technology (ESUT) project.

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    journal_title:BJU international

    pub_type: 杂志文章


    authors: Veneziano D,Canova A,Arnolds M,Beatty JD,Biyani CS,Dehò F,Fiori C,Hellawell GO,Langenhuijsen JF,Pini G,Rodriguez Faba O,Siena G,Skolarikos A,Tokas T,Van Cleynenbreugel BSEP,Wagner C,Tripepi G,Somani B,Lima B

    更新日期:2019-04-01 00:00:00