Abstract：
OBJECTIVES:To determine the feasibility of laparoscopic augmentation cystoplasty (LAC) in the porcine model and to compare LAC using standard bowel vs a small intestinal submucosa (SIS) allograft. MATERIALS AND METHODS:Fourteen female pigs underwent LAC; six had standard ileal AC and eight AC with SIS. All the pigs had limited cystometrogram studies before surgery to determine bladder capacity. At 6 weeks after surgery the pigs were anaesthetized, the bladder capacities were re-assessed and then the pigs were killed; the bladders were harvested and examined histologically. RESULTS:In all, 12 of 14 pigs completed the 6-week survival period; two pigs from the SIS group died from urinary ascites secondary to anastomotic leaks at the cystoplasty site. There were no complications in the ileal augmentation group. The operative duration was similar in both groups. The bladder capacities increased significantly in both groups, although more reliably in the native ileum group. In two pigs in the SIS group there was no increase in bladder capacity. CONCLUSIONS:LAC is feasible in the porcine model and results in a significant increase in bladder capacity. AC using SIS does not appear to increase bladder capacity as reliably as native ileum, and has a higher complication rate.
journal_name
BJU Intjournal_title
BJU internationalauthors
Wang DS,Anderson DA,Fretz PC,Nguyen TT,Winfield HNdoi
10.1111/j.1464-410X.2006.06662.xsubject
Has Abstractpub_date
2007-03-01 00:00:00pages
628-31issue
3eissn
1464-4096issn
1464-410Xpii
BJU6662journal_volume
99pub_type
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pub_type： 杂志文章
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pub_type： 杂志文章,meta分析,评审
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pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章,meta分析
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更新日期：2013-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2013-08-01 00:00:00
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pub_type： 杂志文章,meta分析
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pub_type： 杂志文章,评审
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更新日期：2002-04-01 00:00:00
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更新日期：2007-08-01 00:00:00
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更新日期：2012-03-01 00:00:00
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更新日期：2007-10-01 00:00:00
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更新日期：2012-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2001-08-01 00:00:00
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更新日期：2008-07-01 00:00:00
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