Myelin basic protein inhibits the calcium response to phytohaemagglutinin in human lymphocytes.

abstract：:An adenosine 3'5'-cyclic-monophosphate (Cyclic AMP)-dependent protein kinase has been identified and partially purified from the rat prostate tumor induced by 20-methylcholanthrene. This enzyme is stimulated 2- to 3-fold by the nucleotide. Equilibrium studies at pH 5.0 suggest the presence of a major class of binding ...

journal_title：Bioscience reports

authors： Vijayvargiya R,Singhal RL

更新日期：1982-09-01 00:00:00

abstract：:Erythrocyte membrane is crucial to maintain the stability of erythrocyte structure. The membrane protein on the surface of erythrocyte membrane enables erythrocyte to have plasticity and pass through the microcirculation without being blocked or destroyed. Decreased deformability of erythrocyte membrane protein will l...

journal_title：Bioscience reports

authors： Wang H,Wei HW,Shen HC,Li ZZ,Cheng Y,Duan LS,Yin L,Yu J,Guo JR

更新日期：2020-06-26 00:00:00

abstract：OBJECTIVES:To investigate the association between dectin-1 gene single nucleotide polymorphisms (SNPs) and susceptibility to fungal infection (FI). METHODS:Databases were searched electronically and manually to identify case-control studies concerning dectin-1 SNPs and FI, which were published up to 12 November 2018. ...

journal_title：Bioscience reports

authors： Zhou P,Xie Y,Yan Z,Liu X,Hua H

更新日期：2019-11-29 00:00:00

abstract：:Long non-coding RNAs (lncRNA) CASC2 is a key player in cancer biology. Our new findings showed that both lncRNA CASC2 and IL-17 were up-regulated in plasma of osteoarthritis patients. Plasma levels of lncRNA CASC2 and IL-17 were significantly and positive correlated only in osteoarthritis patients. Overexpression of l...

journal_title：Bioscience reports

authors： Huang T,Wang J,Zhou Y,Zhao Y,Hang D,Cao Y

更新日期：2019-05-14 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) complicated with non-alcoholic fatty liver disease (NAFLD) is difficult to treat. The present study explored the efficacy of (liraglutide) Lira in treating T2DM complicated with NAFLD. A total of 127 patients suffering from T2DM complicated with NAFLD were enrolled in the present study,...

journal_title：Bioscience reports

authors： Tian F,Zheng Z,Zhang D,He S,Shen J

更新日期：2018-12-21 00:00:00

abstract：:The extracts of Paulownia tomentosa (P. tomentosa) exhibit multiple pharmacological activities. In the present study, P. tomentosa flower polysaccharides (PTFP) were extracted by water decoction and ethanol precipitation, and the immunologic modulations of PTFP against Newcastle disease (ND) vaccine was investigated i...

journal_title：Bioscience reports

authors： Yang H,Zhang P,Xu X,Chen X,Liu Q,Jiang C

更新日期：2019-05-03 00:00:00

abstract：:Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose. Addition of tunicamycin inhibits the glycosylation but not synthesis of the [3H]leucine-labelled polypeptide. Secretion of the non-glycosylated protein ...

journal_title：Bioscience reports

authors： Bradshaw JP,White DA

更新日期：1985-03-01 00:00:00

abstract：:Stromal cell derived factor-1 (SDF-1) and basic fibroblast growth factor (bFGF) were reported to induce the differentiation of bone marrow stem cells (BMSCs) into cells with characteristics of periodontal ligament fibroblasts. Thus SDF-1 and bFGF may play a positive role in BMSCs-mediated periodontal ligament regenera...

journal_title：Bioscience reports

authors： Xu M,Wei X,Fang J,Xiao L

更新日期：2019-12-20 00:00:00

abstract：OBJECTIVE:The role of lncRNAs in tumor has been widely concerned. The present study took HAS2-AS1 (the antisense RNA 1 of HAS2) as a starting point to explore its expression in glioma and its role in the process of migration and invasion, providing a strong theoretical basis for mining potential therapeutic targets of ...

journal_title：Bioscience reports

authors： Wang J,Gu J,You A,Li J,Zhang Y,Rao G,Ge X,Zhang K,Li J,Liu X,Wang Q,Lin T,Cheng L,Zhu M,Wu X,Wang D

更新日期：2020-08-28 00:00:00

abstract：:Antimicrobial peptides are a promising resource for developing novel antibiotic and even anticancer drugs. Here, a 28-mer polypeptide, Ranatuerin-2PLx (R2PLx), was identified from lyophilised skin secretions. The chemically synthetic replicates exhibited moderate and broadspectrum antimicrobial effect against various ...

journal_title：Bioscience reports

authors： Chen X,Zhang L,Ma C,Zhang Y,Xi X,Wang L,Zhou M,Burrows JF,Chen T

更新日期：2018-11-09 00:00:00

abstract：:Background: Endometrial carcinoma (EC) still threatens the health of women. Thus, to explore how long intergenic non-protein coding RNA 01220 regulates the development of EC.Methods: Whole genome expression profile data of EC and paracancerous tissues in TCGA database were downloaded. LINC01220 expression in EC and pa...

journal_title：Bioscience reports

authors： Li Y,Kong C,Wu C,Wang Y,Xu B,Liang S,Ying X

更新日期：2019-07-25 00:00:00

abstract：BACKGROUND:Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upward trend in recent years. Nevertheless, little is known regarding effective biomarkers for LUAD. METHODS:The robust rank aggregation method was used to mine differentially expressed genes...

journal_title：Bioscience reports

authors： Song Y,Tang W,Li H

更新日期：2021-01-29 00:00:00

abstract：:In India, Sorghum plant allergenicity was reported to be approximately 54.9%. Sorghum bicolor Polcalcin (Sorb PC) was identified as the panallergen but the specificity of this allergen is yet to be characterized. The present study was aimed to characterize the antigenic determinants of Sorb PC that are responsible for...

journal_title：Bioscience reports

authors： Bokka CS,Veeramachaneni GK,Thunuguntla VBSC,Manda NK,Bondili JS

更新日期：2019-11-29 00:00:00

abstract：:This study proposed a deep learning (DL) algorithm to predict survival in patients with colon adenocarcinoma (COAD) based on multi-omics integration. The survival-sensitive model was constructed using an autoencoder for DL implementation based on The Cancer Genome Atlas (TCGA) data of patients with COAD. The autoencod...

journal_title：Bioscience reports

authors： Lv J,Wang J,Shang X,Liu F,Guo S

更新日期：2020-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a life-threatening chronic cardiopulmonary disorder. However, studies providing PAH-related gene expression profiles are scarce. To identify hub genes involved in PAH, we investigate two microarray data sets from gene expression omnibus (GEO). A total of 150 differentially expr...

journal_title：Bioscience reports

authors： Ma Y,Chen SS,Feng YY,Wang HL

更新日期：2020-09-30 00:00:00

abstract：:Hematopoietic pre-B cell leukemia transcription factor (PBX)-interacting protein (RRBP1) has been shown to participate in various aspects of malignancies. The clinical significance of RRBP1 and its involvement in the epithelial ovarian cancer have yet to be studied. The aim of the present study was to investigate the ...

journal_title：Bioscience reports

authors： Ma J,Ren S,Ding J,Liu S,Zhu J,Ma R,Meng F

更新日期：2019-07-23 00:00:00

abstract：:Our study aimed at exploring the effects of miR-211 on the proliferation and apoptosis of lens epithelial cells in diabetic cataract mice by targetting NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). Healthy male mice were assigned into normal and diabetic cataract groups. Blood glucose, lens turbidity, and apo...

journal_title：Bioscience reports

authors： Zeng K,Feng QG,Lin BT,Ma DH,Liu CM

更新日期：2017-07-27 00:00:00

abstract：:A family of artificial proteins, named αRep, based on a natural family of helical repeat was previously designed. αRep members are efficiently expressed, folded and extremely stable proteins. A large αRep library was constructed creating proteins with a randomized interaction surface. In the present study, we show tha...

journal_title：Bioscience reports

authors： Chevrel A,Urvoas A,Li de la Sierra-Gallay I,Aumont-Nicaise M,Moutel S,Desmadril M,Perez F,Gautreau A,van Tilbeurgh H,Minard P,Valerio-Lepiniec M

更新日期：2015-06-12 00:00:00

abstract：:Insulin stimulated a concentration-dependent increase in protein synthesis in L6 myoblasts which was significant at 1 nM. This response was not prevented by the transcription inhibitor, actinomycin D. The protein kinase C (PKC) inhibitor, Ro-31-8220, and downregulation of PKC by prolonged incubation of cells with 12-O...

journal_title：Bioscience reports

authors： Thompson MG,Pascal M,Mackie SC,Thom A,Morrison KS,Backwell FR,Palmer RM

更新日期：1995-02-01 00:00:00

abstract：:eNOS (endothelial nitric oxide synthase) contains a MAPK (mitogen-activated protein kinase)-binding site associated with a major eNOS control element. Purified ERK (extracellular-signal-regulated kinase) phosphorylates eNOS with a stoichiometry of 2-3 phosphates per eNOS monomer. Phosphorylation decreases NO synthesis...

journal_title：Bioscience reports

authors： Salerno JC,Ghosh DK,Razdan R,Helms KA,Brown CC,McMurry JL,Rye EA,Chrestensen CA

更新日期：2014-09-17 00:00:00

abstract：:The large size of a 1.5-MDa ice-binding adhesin [MpAFP (Marinomonas primoryensis antifreeze protein)] from an Antarctic Gram-negative bacterium, M. primoryensis, is mainly due to its highly repetitive RII (Region II). MpAFP_RII contains roughly 120 tandem copies of an identical 104-residue repeat. We have previously d...

journal_title：Bioscience reports

authors： Vance TD,Olijve LL,Campbell RL,Voets IK,Davies PL,Guo S

更新日期：2014-07-04 00:00:00

abstract：:Peanut (Arachis hypogaea) seed lectin, PNA is widely used to identify tumor specific antigen (T-antigen), Galbeta1-3GalNAc on the eukaryotic cell surface. The functional amino acid coding region of a cDNA clone, pBSH-PN was PCR amplified and cloned downstream of the polyhedrin promoter in the Autographa californica nu...

journal_title：Bioscience reports

authors： Kumar M,Behera AK,Kumar S,Srinivas VR,Das HR,Surolia A,Das RH

更新日期：1999-06-01 00:00:00

abstract：:The sodium contents of beta-cell-rich pancreatic islets from ob/ob-mice were measured with an integrating flame photometer. After washing to an apparent steady state with different types of ice-cold media, islets incubated in the absence of glucose contained 79-108 mmol sodium kg-1 dry weight. Exposure to glucose resu...

journal_title：Bioscience reports

authors： Wesslén N,Bergsten P,Hellman B

更新日期：1986-11-01 00:00:00

abstract：:Aim: In previous studies, numerous dysregulated long non-coding RNAs (lncRNAs) were identified by RNA-sequencing (RNA-seq). However, the relationship between lncRNA and osteosarcoma remains unclear. In the present study, the function and mechanism of lncRNA BE503655 were investigated. Methods: Transwell, cell cycle an...

journal_title：Bioscience reports

authors： Huang Q,Shi SY,Ji HB,Xing SX

更新日期：2019-07-29 00:00:00

abstract：:Trypsin-releasable glycosaminoglycans from the luminal surface of intact pig aorta were measured following metabolic labelling with [35S]sulphate. Chondroitin sulphate was found to be present at a surface density equal to that already established for heparan sulphate (5 X 10(11) chains per cm2). This result was confir...

journal_title：Bioscience reports

authors： Hale G,Streeter HB,Hann AC,Gacesa P,Wusteman FS

更新日期：1987-03-01 00:00:00

abstract：:Safflower (Carthamus tinctorius L.) serves as a reference dicot for investigation of defence mechanisms in Asteraceae due to abundant secondary metabolites and high resistance/tolerance to environmental stresses. In plants, phenylpropanoid and flavonoid pathways are considered as two central defence signalling cascade...

journal_title：Bioscience reports

authors： Dehghan S,Sadeghi M,Pöppel A,Fischer R,Lakes-Harlan R,Kavousi HR,Vilcinskas A,Rahnamaeian M

更新日期：2014-06-25 00:00:00

abstract：:Mitochondrial disorders encompass any medical specialty and affect patients at any age. Likewise, the spectrum of clinical and genetic signatures of these disorders is ample, making a precise diagnosis difficult. We will report some of the major clinical phenotypes observed in infancy, their underlining molecular feat...

journal_title：Bioscience reports

authors： Carrozzo R,Piemonte F,Tessa A,Lucioli S,Rizza T,Meschini MC,Fattori F,Santorelli FM

更新日期：2007-06-01 00:00:00

abstract：:A consensus about the prognostic role of NIMA-related kinase 2 (NEK2) expression in various solid tumors has not been made yet. Thus, this meta-analysis aimed to systematically assess the prognostic role of NEK2 expression in patients with solid tumors. The eligible studies were identified through searching PubMed, We...

journal_title：Bioscience reports

authors： Wang X,Chen K,Liu H,Huang Z,Chen X,Yin L

更新日期：2019-01-18 00:00:00

abstract：:Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI congruent to 10(-6) M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS i...

journal_title：Bioscience reports

authors： Shennan DB,Boyd CA

更新日期：1986-10-01 00:00:00

abstract：:We investigated the possible translational role which elevated concentrations of highly purified Semliki Forest virus (SFV) capsid (C)-protein molecules may play in a cell-free translation system. Here we demonstrate that in the absence of double-stranded RNA high concentrations of C protein triggered the phosphorylat...

journal_title：Bioscience reports

authors： Favre D,Studer E,Michel MR

更新日期：1996-12-01 00:00:00