Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelial.

abstract：OBJECTIVE:Despite advances in therapy, lung cancer is still the leading cause of cancer-related mortality in the world. Further prognostic tools are warranted for risk-adapted therapeutic decisions. We analysed a cohort of primary surgically treated non-small cell lung cancers (NSCLCs) to determine the prognostic role ...

journal_title：Journal of clinical pathology

authors： Augustin F,Fiegl M,Schmid T,Pomme G,Sterlacci W,Tzankov A

更新日期：2015-05-01 00:00:00

abstract：:Eosinophil polymorphonuclear leucocytes (polymorphs) were counted in 45 specimens from patients with Hodgkin's disease and five specimens from patients with reactive follicular hyperplasia. The use of chlorazol fast pink BK, a little known stain for eosinophil polymorphs, combined with image analysis facilitated rapid...

journal_title：Journal of clinical pathology

authors： Fuggle WJ,Crocker J,Smith PJ

更新日期：1984-03-01 00:00:00

abstract：:Three patients with aplastic anaemia had a history of substantial previous exposure to organochlorine pesticides. The temporal association between chemical exposure and the onset of first symptoms of anaemia was strongly supportive. Organochlorines have the property of lipid affinity and accumulation in adipose tissue...

journal_title：Journal of clinical pathology

authors： Rugman FP,Cosstick R

更新日期：1990-02-01 00:00:00

abstract：AIMS:The aim of this study is to explore DNA hypermethylation analysis in sputum and exhaled breath analysis for their complementary, non-invasive diagnostic capacity in lung cancer. METHODS:Sputum samples and exhaled breath were prospectively collected from 20 lung cancer patients and 31 COPD controls (Set 1). An add...

journal_title：Journal of clinical pathology

authors： Hubers AJ,Brinkman P,Boksem RJ,Rhodius RJ,Witte BI,Zwinderman AH,Heideman DA,Duin S,Koning R,Steenbergen RD,Snijders PJ,Smit EF,Sterk PJ,Thunnissen E

更新日期：2014-08-01 00:00:00

abstract：AIMS:Strong thyroglobulin immunoreactivity within sinus histiocytes in a lymph node draining a papillary thyroid carcinoma was observed in a recent case. This prompted the investigation of whether thyroglobulin immunoreactivity is common in regional lymph nodes in cases of thyroid malignancy. METHODS:Eighty seven lymp...

journal_title：Journal of clinical pathology

authors： Venkatraman L,Maxwell P,McCluggage WG

更新日期：2001-04-01 00:00:00

abstract：AIMS:To document the features of the so-called aplastic presentation of childhood acute lymphoblastic leukaemia (ALL) and to determine whether this prodrome can be distinguished from aplasia. METHODS:The peripheral blood and bone marrow appearances of all cases of childhood ALL presenting in one health region of Engla...

journal_title：Journal of clinical pathology

authors： Reid MM,Summerfield GP

更新日期：1992-08-01 00:00:00

abstract：:The hepatic and splenic storage iron, including the relative distribution between ferritin and haemosiderin, was estimated in 130 necropsies including normal accident cases and cases with a variety of diseases. The storage iron was also examined histochemically. It was found that in the normal subjects, on the average...

journal_title：Journal of clinical pathology

authors： Morgan EH,Walters MN

更新日期：1963-03-01 00:00:00

abstract：AIMS:To develop a rapid, sensitive, and specific non-isotopic in situ hybridisation (NISH) procedure for the detection of Epstein-Barr virus in formalin fixed, paraffin wax embedded tissues. METHODS:Two low molecular weight RNAs, designated EBER-1 and EBER-2 (Epstein-Barr encoded RNA), were used: cells latently infect...

journal_title：Journal of clinical pathology

authors： Khan G,Coates PJ,Kangro HO,Slavin G

更新日期：1992-07-01 00:00:00

abstract：:Two patients are reported in whom initial misdiagnoses of medullary cancer or trabecular hyaline adenoma for papillary carcinoma were made. ...

journal_title：Journal of clinical pathology

authors： Andrew AC,Williamson JM

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：:Fluorigenic substrates prepared from 4-methylumbelliferone provide a simple, convenient method for detecting and assaying group-specific hydrolase activity in small quantities of whole mycobacteria. Physico-chemical properties of the enzymes such as pH dependence and heat stability may also be studied. A technique is ...

journal_title：Journal of clinical pathology

authors： Grange JM

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Coronary heart disease is associated with increased B-type natriuretic peptides (BNPs), and, although controversial, may cause exaggerated exercise-induced BNP secretion. We investigated BNP in relation to reversible myocardial ischaemia. MATERIALS AND METHODS:Serum N-terminal proBNP (NT-proBNP) was measure...

journal_title：Journal of clinical pathology

authors： Chatha K,Alsoud M,Griffiths MJ,Elfatih A,Abozguia K,Horton RC,Dunmore SJ,Gama R

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:As the best characterised cancer/testis antigen family members, melanoma-associated antigens (MAGE) have been reported to be expressed in various malignant tumours. However, the expression pattern of MAGE-A family in lung adenocarcinoma (LAC) specimens and their prognostic and therapeutic significance for pa...

journal_title：Journal of clinical pathology

authors： Sang M,Gu L,Yin D,Liu F,Lian Y,Zhang X,Liu S,Huang W,Wu Y,Shan B

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Breast cancer is increasing in Indonesia and other developing countries. Germline mutations in the BRCA1/2 genes are most strongly associated with a high risk for breast cancer development. There have been no reports on BRCA1/2 gene mutations in the Indonesian population. Genetic research yielding insight in...

journal_title：Journal of clinical pathology

authors： Purnomosari D,Paramita DK,Aryandono T,Pals G,van Diest PJ

更新日期：2005-05-01 00:00:00

abstract：AIMS:Accurate assessment of HER2 status is essential for selection of patients for HER2-targeted treatment such as trastuzumab. This study investigated the hypothesis that delayed fixation impairs HER2 assessment. METHODS:9 carcinomas were received fresh, and samples were fixed immediately or put in fixative at time i...

journal_title：Journal of clinical pathology

authors： Lee AH,Key HP,Bell JA,Kumah P,Hodi Z,Ellis IO

更新日期：2014-07-01 00:00:00

abstract：:Of 30 children with bleeding disorders exposed to an index tuberculosis case, six developed primary pulmonary tuberculosis and two others became positive skin reactors. There was a significant correlation between the amount of replacement treatment received and the development of evidence of tuberculous infection. Onl...

journal_title：Journal of clinical pathology

authors： Beddall AC,Hill FG,George RH,Williams MD,Al-Rubei K

更新日期：1985-10-01 00:00:00

abstract：AIMS:The aims of the study were to compare bacterial recovery following storage of sputum samples at 20 degrees C room temperature and 4 degrees C (refrigerated) for 24 h, and to determine the effect of postage on viable bacterial numbers. METHODS:A total of 38 individual sputum samples from clinically stable patients...

journal_title：Journal of clinical pathology

authors： Pye A,Hill SL,Bharadwa P,Stockley RA

更新日期：2008-03-01 00:00:00

abstract：AIMS:An increase in the proliferative state of the gastric epithelium has been attributed to infection with Helicobacter pylori. In order to obtain a more precise estimate of the magnitude of this change, the proliferative state of 17 cases of florid H pylori associated follicular gastritis was examined using the antib...

journal_title：Journal of clinical pathology

authors： Havard TJ,Sarsfield P,Wotherspoon AC,Steer HW

更新日期：1996-01-01 00:00:00

abstract：:A 19 year old man presented with unilateral testicular swelling and pain. An initial diagnosis of epididymo-orchitis was modified to a presumed testicular neoplasm following ultrasonography. The final diagnosis of isolated testicular vasculitis was established following histological examination of the orchidectomy spe...

journal_title：Journal of clinical pathology

authors： Warfield AT,Lee SJ,Phillips SM,Pall AA

更新日期：1994-12-01 00:00:00

abstract：AIMS:To investigate whether the use of recombinant early antigens for detection of antibodies to human cytomegalovirus (HCMV) gene products CM(2) (UL44, UL57) and p52 (UL44) is specific in the diagnosis and differentiation of active HCMV infection in a subset of patients with chronic fatigue syndrome (CFS), a diagnosis...

journal_title：Journal of clinical pathology

authors： Beqaj SH,Lerner AM,Fitzgerald JT

更新日期：2008-05-01 00:00:00

abstract：:A method is described for the quantitative separation of radioactive bile acids and neutral sterols in human faeces on a potassium hydroxide-treated silicic acid column. Results obtained with faecal extracts containing metabolites derived from radioactive cholesterol, cholic acid, and chenodeoxycholic acid show that t...

journal_title：Journal of clinical pathology

authors： LEWIS B,MYANT NB

更新日期：1965-01-01 00:00:00

abstract：:This best practice review examines four series of common primary care questions in laboratory medicine: (i) "minor" blood platelet count and haemoglobin abnormalities; (ii) diagnosis and monitoring of anaemia caused by iron deficiency; (iii) secondary hyperlipidaemia and hypertriglyceridaemia; and (iv) glycated haemog...

journal_title：Journal of clinical pathology

authors： Smellie WS,Forth J,Bareford D,Twomey P,Galloway MJ,Logan EC,Smart SR,Reynolds TM,Waine C

更新日期：2006-08-01 00:00:00

abstract：:Isolates of Campylobacter jejuni, C coli, C fetus and C laridis were tested for agglutination reactions with a panel of five lectins: Arachis hypogaea, Bauhinia purpurea, Solanum tuberosum, Triticum vulgaris and Wisteria floribunda. Twenty three patterns of agglutination (lectin types) were recorded among 376 isolates...

journal_title：Journal of clinical pathology

authors： O'Sullivan N,Benjamin J,Skirrow MB

更新日期：1990-11-01 00:00:00

abstract：:Although epithelial mucin has been demonstrated in ordinary mammary duct carcinomas, it is formed profusely in the uncommon mucous carcinomas. A histochemical study of mucous carcinomas of the breast and colon showed that both types produce similar mucins, viz, acid and neutral, although the mammary carcinomas produce...

journal_title：Journal of clinical pathology

authors： Cooper DJ

更新日期：1974-04-01 00:00:00

abstract：AIMS:To assess the occurrence of diagnostic delay in primary antibody deficiency in the period 1989-2002, since a similar study in 1989, and to assess the impact of UK national guidelines communicated in 1995. METHODS:A retrospective case note review was performed of 89 consecutive patients with antibody deficiency re...

journal_title：Journal of clinical pathology

authors： Seymour B,Miles J,Haeney M

更新日期：2005-05-01 00:00:00

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：:The use of liquid media to detect the production of beta-lactamase by beta-lactamase producing organisms has been compared with the conventional method of inoculation on to agar media. Pharyngeal cultures were obtained from 162 children treated with penicillin for acute tonsillitis. beta-lactamase producing organisms ...

journal_title：Journal of clinical pathology

authors： Brook I,Gober AE

更新日期：1984-12-01 00:00:00

abstract：:The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinom...

journal_title：Journal of clinical pathology

authors： Boughton BJ

更新日期：1979-06-01 00:00:00

abstract：:Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoa...

journal_title：Journal of clinical pathology

authors： Riyami BM,Tree R,Kinsella J,Clark CJ,Reid WH,Campbell D,Gemmell CG

更新日期：1990-01-01 00:00:00

abstract：:The biochemical classification of the Klebsiella proposed by Cowan, Steel, Shaw, and Duguid (1960) has been applied to 50 strains isolated as the pure or predominant growth from sputum, and Klebsiella species have been correlated with the severity of the chest infection in the patient. A modification in nomenclature i...

journal_title：Journal of clinical pathology

authors： FOSTER WD,BRAGG J

更新日期：1962-09-01 00:00:00