Statins in the intensive care unit.

abstract：PURPOSE OF REVIEW:This review intends to summarize the recent findings regarding the presence of increased oxidative stress in critically ill patients and its potential pathophysiologic role, as well as the results of recent clinical trials of antioxidant therapies. RECENT FINDINGS:Several lines of evidence confirm th...

journal_title：Current opinion in critical care

authors： Lovat R,Preiser JC

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Since the 1980s, hypocaloric feeding has been regularly proposed in the critically ill, although there is no clear definition available, nor evidence-based strategy to support it. We aim to define hypocaloric feeding based on indirect calorimetric data and to discuss patient-relevant clinical outcomes...

journal_title：Current opinion in critical care

authors： Berger MM,Chioléro RL

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The ultimate goal of cardiopulmonary resuscitation is long-term neurologically intact survival. Despite numerous well-designed studies, the medications currently used in advanced cardiac life support have not demonstrated success in this regard. This review describes the novel therapeutics under inves...

journal_title：Current opinion in critical care

authors： Bartos JA,Yannopoulos D

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac arrest is one of the most challenging disease processes to study with clinical trials due to the emergent and unpredictable nature of these events and complexity of the patient population. In recent years, there has been a major push to complete more large, multicentre trials. In many cases, h...

journal_title：Current opinion in critical care

authors： Berg KM

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The gut has long been hypothesized to be the 'motor' of multiple organ dysfunction syndrome. This review serves as an update on new data elucidating the role of the gut as the propagator of organ failure in critical illness. RECENT FINDINGS:Under basal conditions, the gut absorbs nutrients and serves...

journal_title：Current opinion in critical care

authors： Meng M,Klingensmith NJ,Coopersmith CM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Successful treatment of cardiac arrest requires that an electrically stable and mechanically competent cardiac activity be promptly reestablished. However, many interventions used to attempt to reestablish cardiac activity may also inflict additional myocardial injury and, in turn, compromise resuscit...

journal_title：Current opinion in critical care

authors： Gazmuri RJ,Ayoub IM,Kolarova J

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review the recent literature describing how to assess and treat postcardiac arrest syndrome associated haemodynamics and manage oxygenation and ventilation derangements. RECENT FINDINGS:Postcardiac arrest syndrome is a well described entity that includes systemic ische...

journal_title：Current opinion in critical care

authors： Topjian AA,Berg RA,Taccone FS

更新日期：2015-06-01 00:00:00

abstract：:Intra-abdominal infection continues to pose a significant threat to critically ill patients in the year 2000. A review of the current literature reveals that despite remarkable developments in critical care medicine and extensive study of patients with tertiary peritonitis, the associated mortality rate remains nearly...

journal_title：Current opinion in critical care

authors： Evans HL,Raymond DP,Pelletier SJ,Crabtree TD,Pruett TL,Sawyer RG

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update of recent developments pertaining to the use of percutaneous tracheostomy. Percutaneous tracheostomy has been established as an alternative to open surgical tracheostomy, but many key questions about the optimal use of this procedure remain unanswered...

journal_title：Current opinion in critical care

authors： Bardell T,Drover JW

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the improvements in its management, community-acquired pneumonia (CAP) still exhibits high global morbidity and mortality rates, especially in elderly patients. This review focuses on the most recent findings on the epidemiology, cause, diagnosis and management of CAP. RECENT FINDINGS:There i...

journal_title：Current opinion in critical care

authors： Cillóniz C,Dominedò C,Garcia-Vidal C,Torres A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Securing the airway to provide sufficient oxygenation and ventilation is of paramount importance in the management of all types of emergency patients. Particularly in severely injured patients, strategies should be adapted according to useful recent literature findings. RECENT FINDINGS:The role of ou...

journal_title：Current opinion in critical care

authors： Beckers SK,Brokmann JC,Rossaint R

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent developments in preventing and treating postoperative acute renal dysfunction. To review contemporary issues concerning perioperative fluid and electrolyte management. RECENT FINDINGS:Renal dysfunction remains a major postoperative morbidity despite the advent of intermittent and co...

journal_title：Current opinion in critical care

authors： Hashem R,Weissman C

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients. RECENT FINDINGS:The choice of perioperative haemodynamic monito...

journal_title：Current opinion in critical care

authors： Kirov MY,Kuzkov VV,Molnar Z

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Mechanical ventilation is a cornerstone of ICU treatment. Because of its interaction with blood flow and intra-abdominal pressure, mechanical ventilation has the potential to alter hepato-splanchnic perfusion, abdominal organ function and thereby outcome of the most critically ill patients. RECENT FI...

journal_title：Current opinion in critical care

authors： Jakob SM

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...

journal_title：Current opinion in critical care

authors： Burlew CC,Biffl WL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. This review provides an overview of these new clinical data and also explores new areas of investigation for HFOV in ...

journal_title：Current opinion in critical care

authors： Ng J,Ferguson ND

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy. RECENT...

journal_title：Current opinion in critical care

authors： Brohi K,Cohen MJ,Davenport RA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern technologies allow visualization of microcirculatory disorders. This review describes how the coagulatory inhibitors antithrombin and activated protein C (APC) can improve microcirculation in sepsis and transplantation. RECENT FINDINGS:The effects of antithrombin and APC on microcirculatory di...

journal_title：Current opinion in critical care

authors： Hoffmann JN,Fertmann JM,Jauch KW

更新日期：2006-10-01 00:00:00

abstract：:The use of therapeutic moderate hypothermia for treating severe traumatic brain injury has been reported for more than 50 years. However, the most intense investigation of this treatment has occurred during the last 10 to 15 years. Virtually all preclinical studies have documented a robust treatment effect, not only i...

journal_title：Current opinion in critical care

authors： Marion DW

更新日期：2002-04-01 00:00:00

abstract：:Widespread provision of early defibrillation following cardiac arrest holds major promise for improved survival from ventricular fibrillation. The critical element in predicting a successful outcome is the rapidity with which defibrillation is achieved. A worldwide awareness of this potential and its advocacy by such ...

journal_title：Current opinion in critical care

authors： White RD

更新日期：2001-06-01 00:00:00

abstract：:Critical illness polyneuropathy (CIP) is a syndrome that was first extensively described in the early 1980s, mainly in patients with failure to wean from mechanical ventilation. The syndrome is further characterized by limb muscle weakness, usually more pronounced distally than proximally, and is often accompanied by ...

journal_title：Current opinion in critical care

authors： van Mook WN,Hulsewé-Evers RP

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article will review the current state of our understanding of nephrotoxic medication-associated acute kidney injury (AKI) and provide strategies to reduce its impact. RECENT FINDINGS:Nephrotoxic medications contribute to a substantial proportion of AKI in hospitalized patients. The previo...

journal_title：Current opinion in critical care

authors： Goldstein SL

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the current intensive care management of acute liver failure (ALF) and the latest evidence for emerging therapies. RECENT FINDINGS:Mortality from ALF continues to improve and in some cases, medical therapy can negate the need for liver transplantation because of protocolized man...

journal_title：Current opinion in critical care

authors： Trovato FM,Rabinowich L,McPhail MJW

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:There is growing evidence that bone health is impacted during and after critical illness in multiple ways. In this review, we provide a practical update on postcritical care bone loss with an insight on identification of persons at risk, prevention and treatment strategies. RECENT FINDINGS:Critical i...

journal_title：Current opinion in critical care

authors： Rousseau AF,Kerschan-Schindl K,Scherkl M,Amrein K

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Appropriate measurements of success in trauma systems are evolving. We review the rationale behind prior trauma and rehabilitation outcomes measures, and how they have led to the current rehabilitation tools in use today. In addition, we review the difficulties with current methods and future improvem...

journal_title：Current opinion in critical care

authors： Horwitz DA,Schuerer DJ

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review will discuss the usefulness of ultrasound in the ICU in assessing hemodynamic instability in various critical care conditions. We will discuss how to interpret echocardiographic findings in critically ill patients including the physiological consequences of mechanical ventilation. ...

journal_title：Current opinion in critical care

authors： Salem R,Vallee F,Rusca M,Mebazaa A

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Over the past decades, survival of critically ill hematological patients has dramatically improved, and these patients are more frequently referred to the ICU for intensive treatment, including a rising need for administering anticancer-therapy in this setting. RECENT FINDINGS:The scarce literature o...

journal_title：Current opinion in critical care

authors： Moors I,Pène F,Lengline É,Benoit D

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Multimodal monitoring has emerged as a novel paradigm of care in acute brain injury, and in this context the value of noninvasive devices is increasingly under scrutiny. This narrative review summarizes recent clinical investigation focused on the role of automated infrared pupillometry (AIP) and opti...

journal_title：Current opinion in critical care

authors： Romagnosi F,Bongiovanni F,Oddo M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Although conventional anticonvulsant agents can terminate status epilepticus in most cases, a substantial minority of patients develops medically refractory status and requires more aggressive care. This review explores the options available. RECENT FINDINGS:Increasing numbers of previously unexpecte...

journal_title：Current opinion in critical care

authors： Bleck TP

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasin...

journal_title：Current opinion in critical care

authors： Festic E,Kor DJ,Gajic O

更新日期：2015-02-01 00:00:00