Update on the management of acute liver failure.

abstract：PURPOSE OF REVIEW:Glutamine (GLN) is a versatile amino acid, long believed to have important implications in ICU and surgical patients. An extensive body of data examining GLN supplementation of TPN demonstrated a consistent signal of improved outcomes. However, recently signals of risk have come from two large-scale m...

journal_title：Current opinion in critical care

authors： Wischmeyer PE

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of re...

journal_title：Current opinion in critical care

authors： Pineton de Chambrun M,Bréchot N,Combes A

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is commonplace in most ICUs. In many cases the cause is believed to be multifactorial with sepsis being a major component. However, occasionally intrinsic renal disease will present to the ICU and as such critical care practitioners should be aware of this possibility and the...

journal_title：Current opinion in critical care

authors： Amery CE,Forni LG

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Over the past decades, survival of critically ill hematological patients has dramatically improved, and these patients are more frequently referred to the ICU for intensive treatment, including a rising need for administering anticancer-therapy in this setting. RECENT FINDINGS:The scarce literature o...

journal_title：Current opinion in critical care

authors： Moors I,Pène F,Lengline É,Benoit D

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:There is significant controversy for perioperative fluid management. This review discusses the evidence from clinical studies, basic research, and systematic reviews to provide a summary of the current best practice in this area. RECENT FINDINGS:Recent evidence has challenged the long-held contention...

journal_title：Current opinion in critical care

authors： Peng ZY,Kellum JA

更新日期：2013-08-01 00:00:00

abstract：:This review discusses the myocardial protective property of the insulin/glucose-insulin-potassium regimen and the mechanisms involved in this beneficial action. Several recent studies suggest that insulin not only is useful to control hyperglycemia and maintain glucose homeostasis but also may have the unique property...

journal_title：Current opinion in critical care

authors： Das UN

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Traumatic injury continues to be a significant cause of morbidity and mortality in the year 2011. In addition, the healthcare expenditures and lost years of productivity represent significant economic cost to the affected individuals and their communities. Helicopters have been used to transport traum...

journal_title：Current opinion in critical care

authors： Plevin RE,Evans HL

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutic hypothermia following out-of-hospital cardiac arrest improves neurological recovery. Coupled with neurological benefit, multiple complications including infection have been associated with therapeutic hypothermia following out-of-hospital cardiac arrest. In this review, we will discuss the...

journal_title：Current opinion in critical care

authors： Kuchena A,Merkel MJ,Hutchens MP

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. This review provides an overview of these new clinical data and also explores new areas of investigation for HFOV in ...

journal_title：Current opinion in critical care

authors： Ng J,Ferguson ND

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

journal_title：Current opinion in critical care

authors： Edwards D,Nirmalan M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Survivorship or addressing impaired quality of life (QoL) in ICU survivors has been named 'the defining challenge of critical care' for this century to address this challenge; in addition to optimal nutrition, we must learn to employ targeted metabolic/muscle assessment techniques and utilize structur...

journal_title：Current opinion in critical care

authors： Molinger J,Pastva AM,Whittle J,Wischmeyer PE

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:There is growing evidence that bone health is impacted during and after critical illness in multiple ways. In this review, we provide a practical update on postcritical care bone loss with an insight on identification of persons at risk, prevention and treatment strategies. RECENT FINDINGS:Critical i...

journal_title：Current opinion in critical care

authors： Rousseau AF,Kerschan-Schindl K,Scherkl M,Amrein K

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Conventional intermittent hemodialysis and continuous veno-venous hemofiltration are the opposite poles of current treatment modalities for patients with acute renal failure in the intensive care unit. Because both intermittent and continuous renal replacement techniques have several disadvantages, al...

journal_title：Current opinion in critical care

authors： Fliser D,Kielstein JT

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We sought to review the evidence supporting neurocritical care as a distinct specialty of medicine. RECENT FINDINGS:Over the past 20 years, neuro-intensive care units have evolved from neurosurgical units focused primarily on postoperative monitoring to units that provide comprehensive medical and sp...

journal_title：Current opinion in critical care

authors： Rincon F,Mayer SA

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins are effective lipid-lowering agents used extensively in medical practice. This review summarizes the evidence for statin treatment of cardiovascular patients in the intensive care unit and briefly discusses the role of statins in prevention and treatment of sepsis as a potential future applica...

journal_title：Current opinion in critical care

authors： Merx MW,Weber C

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Nutritional status and nutrient delivery during critical illness impact clinical outcomes. We have reviewed recent studies that may guide best practices regarding nutrition therapy in critically ill children. RECENT FINDINGS:Malnutrition is prevalent in the pediatric ICU population, and is associated...

journal_title：Current opinion in critical care

authors： Martinez EE,Mehta NM

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of r...

journal_title：Current opinion in critical care

authors： Cantón R,Gijón D,Ruiz-Garbajosa P

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Management of the patient with traumatic brain injury is a rapidly advancing field, characterized in recent years by an improved understanding of intracranial pathophysiology and ways in which outcomes can be improved. Many traditional therapies, such as fluid restriction and hyperventilation, have be...

journal_title：Current opinion in critical care

authors： Dutton RP,McCunn M

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although vitamin C is essentially a nontoxic vitamin; however, it is important to be aware regarding the safety of high doses before the wide clinical use. RECENT FINDINGS:Minor side effects of vitamin C have been reported, many being reported in earlier studies. High doses of vitamin C (up to 1.5 g/...

journal_title：Current opinion in critical care

authors： Khoshnam-Rad N,Khalili H

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe acute respiratory syndrome (SARS) is a new disease that caused large outbreaks in several countries in the first half of 2003, resulting in infection in more than 8000 people and more than 900 deaths. During that time, a large body of literature rapidly emerged describing the clinical disease, ...

journal_title：Current opinion in critical care

authors： Lapinsky SE,Granton JT

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications...

journal_title：Current opinion in critical care

authors： Perkins ZB,Lendrum RA,Brohi K

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the improvements in its management, community-acquired pneumonia (CAP) still exhibits high global morbidity and mortality rates, especially in elderly patients. This review focuses on the most recent findings on the epidemiology, cause, diagnosis and management of CAP. RECENT FINDINGS:There i...

journal_title：Current opinion in critical care

authors： Cillóniz C,Dominedò C,Garcia-Vidal C,Torres A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

journal_title：Current opinion in critical care

authors： Kortgen A,Recknagel P,Bauer M

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple factors influence the dependability of intensive care provision. The management of a group of unstable, critically ill patients requires focused attention from the clinical team. Medical simulation is an important tool to improve safety and team work within the ICU. RECENT FINDINGS:The criti...

journal_title：Current opinion in critical care

authors： Fox-Robichaud AE,Nimmo GR

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:End-of-life care and communication deficits are important sources of conflicts within ICU teams and with patients or families. This narrative review describes recent studies on how to improve palliative care and surrogate decision-making in ICUs and compares the results with previously published liter...

journal_title：Current opinion in critical care

authors： Wiedermann CJ,Lehner GF,Joannidis M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

journal_title：Current opinion in critical care

authors： Douglas JJ,Walley KR

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Progress has been made in our understanding of gut dysfunction in critical illness. This review will outline new findings and give perspectives based on previous knowledge and concurrent advances in nutrition. RECENT FINDINGS:The relationship between gut dysfunction and poor outcomes in critical illn...

journal_title：Current opinion in critical care

authors： Chapple LS,Plummer MP,Chapman MJ

更新日期：2021-01-21 00:00:00

abstract：PURPOSE OF REVIEW:Despite improved care of multiple injured patients, controversial data about the best time point for decompression and stabilization of spine fractures and spinal cord injuries are published. Some studies even question the value of surgical management. RECENT FINDINGS:In several mostly retrospective ...

journal_title：Current opinion in critical care

authors： Schinkel C,Anastasiadis AP

更新日期：2008-12-01 00:00:00