Eyeing up the injured brain: automated pupillometry and optic nerve sheath diameter.


PURPOSE OF REVIEW:Multimodal monitoring has emerged as a novel paradigm of care in acute brain injury, and in this context the value of noninvasive devices is increasingly under scrutiny. This narrative review summarizes recent clinical investigation focused on the role of automated infrared pupillometry (AIP) and optic nerve sheath diameter (ONSD) ultrasound as novel techniques to monitor and manage neurocritical care patients. RECENT FINDINGS:AIP provides a quantitative measurement of the pupillary light reflex that is more precise and reliable than the traditional examination of the pupillary light reflex using manual flashlight lamps. AIP helps detect raised intracranial pressure (ICP) and brain herniation in patients with intracranial mass lesions. Using an automatically computed scalar index - the neurological pupil index - AIP has great accuracy to predict poor neurological outcome in patients in coma after cardiac arrest. Recent data indicate that ONSD may diagnose intracranial hypertension with better accuracy than other ultrasound-based methods. SUMMARY:Noninvasive AIP and ONSD appear useful complements to multimodality monitoring of acute brain injury, in particular in patients at risk of elevated ICP and for early neuroprognostication following cardiac arrest.


Curr Opin Crit Care


Romagnosi F,Bongiovanni F,Oddo M




Has Abstract


2020-04-01 00:00:00












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    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审


    authors: Amaya-Villar R,Garnacho-Montero J

    更新日期:2019-10-01 00:00:00

  • Insulin: an endogenous cardioprotector.

    abstract::This review discusses the myocardial protective property of the insulin/glucose-insulin-potassium regimen and the mechanisms involved in this beneficial action. Several recent studies suggest that insulin not only is useful to control hyperglycemia and maintain glucose homeostasis but also may have the unique property...

    journal_title:Current opinion in critical care

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    authors: Das UN

    更新日期:2003-10-01 00:00:00

  • Advancements in the critical care management of status epilepticus.

    abstract:PURPOSE OF REVIEW:Status epilepticus has a high morbidity and mortality. There are little definitive data to guide management; however, new recent data continue to improve understanding of management options of status epilepticus. This review examines recent advancements regarding the critical care management of status...

    journal_title:Current opinion in critical care

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    authors: Bauerschmidt A,Martin A,Claassen J

    更新日期:2017-04-01 00:00:00

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    journal_title:Current opinion in critical care

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    journal_title:Current opinion in critical care

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    authors: Flaatten H

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    更新日期:2009-08-01 00:00:00

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    authors: Ranzani OT,De Pascale G,Park M

    更新日期:2018-10-01 00:00:00

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    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审


    authors: Dutton RP,McCunn M

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    authors: Steen PA,Kramer-Johansen J

    更新日期:2008-06-01 00:00:00

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    更新日期:2015-12-01 00:00:00

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    authors: Ait-Oufella H,Bourcier S,Lehoux S,Guidet B

    更新日期:2015-08-01 00:00:00

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    journal_title:Current opinion in critical care

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    authors: Groeneveld AB,Molenaar N,Beishuizen B

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    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审


    authors: Fassier T,Lautrette A,Ciroldi M,Azoulay E

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    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审


    authors: Lapinsky SE,Granton JT

    更新日期:2004-02-01 00:00:00