Abstract:
PURPOSE OF REVIEW:Despite the improvements in its management, community-acquired pneumonia (CAP) still exhibits high global morbidity and mortality rates, especially in elderly patients. This review focuses on the most recent findings on the epidemiology, cause, diagnosis and management of CAP. RECENT FINDINGS:There is consistent evidence that the trend in CAP mortality has declined over time. However, the mortality of pneumococcal CAP has not changed in the last two decades, with an increase in the rate of hospitalization and more severe forms of CAP. Streptococcus pneumoniae remains the most frequent cause of CAP in all settings, age groups and regardless of comorbidities. However, the implementation of molecular diagnostic tests in the last years has identified respiratory viruses as a common cause of CAP too. The emergency of multidrug-resistance pathogens is a worldwide concern. An improvement in our ability to promptly identify the causative cause of CAP is required in order to provide pathogen-directed antibiotic therapy, improve antibiotic stewardship programs and implement appropriate vaccine strategies. SUMMARY:It is time to apply all the knowledge generated in the last decade in order to optimize the management of CAP.
journal_name
Curr Opin Crit Carejournal_title
Current opinion in critical careauthors
Cillóniz C,Dominedò C,Garcia-Vidal C,Torres Adoi
10.1097/MCC.0000000000000550subject
Has Abstractpub_date
2018-12-01 00:00:00pages
531-539issue
6eissn
1070-5295issn
1531-7072journal_volume
24pub_type
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/00075198-200404000-00006
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0b013e3282f827d3
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/01.ccx.0000130150.33814.71
更新日期:2004-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Delirium is frequently encountered in the ICU and is associated with significant adverse outcomes. The increasingly recognized consequences of ICU delirium should enhance efforts to improve recognition and management of this serious problem. We aim to review the recent literature on ICU delirium, incl...
journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2019-10-01 00:00:00
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journal_title:Current opinion in critical care
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2016-08-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2007-12-01 00:00:00
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journal_title:Current opinion in critical care
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更新日期:2003-12-01 00:00:00
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journal_title:Current opinion in critical care
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0b013e3283632d5e
更新日期:2013-08-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章
doi:10.1097/MCC.0000000000000790
更新日期:2021-02-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0b013e32801297f9
更新日期:2007-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...
journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0b013e32833ee8b4
更新日期:2010-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Antimicrobials are very commonly used drugs in the intensive care setting. Extensive research has been conducted in recent years to describe their pharmacokinetics/pharmacodynamics in order to maximize the pharmacological benefit and patient outcome. Translating these new findings into clinical practi...
journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0000000000000229
更新日期:2015-10-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0000000000000710
更新日期:2020-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The comparison of morbidity, mortality, and length-of-stay outcomes in patients receiving critical care requires adjustment based on their presenting illness. These adjustments are made with severity-of-illness models. These models must be periodically updated to reflect current medical practices. Thi...
journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0b013e3283101643
更新日期:2008-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Mechanical ventilation is the main supportive therapy for patients with acute respiratory distress syndrome. As with any therapy, mechanical ventilation has side effects and may induce lung injury. This review will focus on stretch-dependent activation of alveolar epithelial and endothelial cells and ...
journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/00075198-200502000-00013
更新日期:2005-02-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章
doi:10.1097/00075198-200008000-00005
更新日期:2000-08-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/MCC.0000000000000254
更新日期:2015-12-01 00:00:00
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journal_title:Current opinion in critical care
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更新日期:2014-08-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2014-02-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章
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更新日期:2009-12-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
doi:10.1097/00075198-200204000-00004
更新日期:2002-04-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2002-10-01 00:00:00
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更新日期:2006-04-01 00:00:00
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journal_title:Current opinion in critical care
pub_type: 杂志文章,评审
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更新日期:2007-12-01 00:00:00
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journal_title:Current opinion in critical care
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更新日期:2012-02-01 00:00:00