Acute coagulopathy of trauma: mechanism, identification and effect.

abstract：PURPOSE OF REVIEW:Acute liver failure (ALF) is associated with significant mortality. Although specific therapies may be available, the evidence base for these and for many aspects of supportive therapy has been slow to emerge. Liver transplantation continues to be a cornerstone of treatment, and the management of ALF,...

journal_title：Current opinion in critical care

authors： Willars C

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent data about Acinetobacter baumannii pneumonia epidemiology and the therapeutic options including adjunctive nebulized therapy. RECENT FINDINGS:A. baumannii is a major cause of nosocomial pneumonia in certain geographic areas affecting mainly debilitated patients, with prolonged hosp...

journal_title：Current opinion in critical care

authors： Amaya-Villar R,Garnacho-Montero J

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutic hypothermia following out-of-hospital cardiac arrest improves neurological recovery. Coupled with neurological benefit, multiple complications including infection have been associated with therapeutic hypothermia following out-of-hospital cardiac arrest. In this review, we will discuss the...

journal_title：Current opinion in critical care

authors： Kuchena A,Merkel MJ,Hutchens MP

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There are few first-hand accounts that describe the history of outcome prediction in critical care. This review summarizes the authors' personal perspectives about the development and evolution of Acute Physiology and Chronic Health Evaluation over the past 35 years. RECENT FINDINGS:We emphasize what...

journal_title：Current opinion in critical care

authors： Zimmerman JE,Kramer AA

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobials are very commonly used drugs in the intensive care setting. Extensive research has been conducted in recent years to describe their pharmacokinetics/pharmacodynamics in order to maximize the pharmacological benefit and patient outcome. Translating these new findings into clinical practi...

journal_title：Current opinion in critical care

authors： Tsai D,Lipman J,Roberts JA

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose is to review the current application of extracorporeal life support (ECLS) in trauma patients. In addition, programmatic development is described. RECENT FINDINGS:ECLS use is increasing among trauma patients. Several recent studies among trauma patients report survival rates of 65-79%. De...

journal_title：Current opinion in critical care

authors： Zonies D,Merkel M

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Mechanical ventilation is a cornerstone of ICU treatment. Because of its interaction with blood flow and intra-abdominal pressure, mechanical ventilation has the potential to alter hepato-splanchnic perfusion, abdominal organ function and thereby outcome of the most critically ill patients. RECENT FI...

journal_title：Current opinion in critical care

authors： Jakob SM

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS) and acute lung injury remains controversial, although frequent. This review analyzes the effects of NMBAs on thoracopulmonary mechanics, gas exchange, patient outcome and their potential advers...

journal_title：Current opinion in critical care

authors： Forel JM,Roch A,Papazian L

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...

journal_title：Current opinion in critical care

authors： Burlew CC,Biffl WL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantable cardioverter-defibrillator (ICD) implantation is the standard of care for secondary prevention in patients with previous cardiac arrest and for primary prevention in appropriately selected patients with cardiomyopathy. However, ICD therapies and the arrhythmias that trigger these therapies...

journal_title：Current opinion in critical care

authors： Bradfield JS,Buch E,Shivkumar K

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To investigate the impact of critical illness polyneuropathy and critical illness myopathy on short-term and long-term patient outcome. RECENT FINDINGS:In the acute-care setting, critical illness polyneuropathy and critical illness myopathy are important causes of acute paralysis in critically ill co...

journal_title：Current opinion in critical care

authors： Latronico N,Shehu I,Seghelini E

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Care of the injured patient is a dynamic process. Hemorrhage remains the primary cause of preventable death after trauma. Rapid and effective early care can improve survival and outcomes. Emerging therapies to address traumatic hemorrhage will be discussed. RECENT FINDINGS:Current concepts in trauma ...

journal_title：Current opinion in critical care

authors： Sambasivan CN,Schreiber MA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We report on recent advances and achievements on the use of extracorporeal gas exchange for long-term application in the therapy of critically ill patients with various forms of respiratory failure. RECENT FINDINGS:The most important results regarding the use of extracorporeal gas exchange are expect...

journal_title：Current opinion in critical care

authors： Pesenti A,Zanella A,Patroniti N

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. This review provides an overview of these new clinical data and also explores new areas of investigation for HFOV in ...

journal_title：Current opinion in critical care

authors： Ng J,Ferguson ND

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review the prevalence and significance of gasping in patients experiencing cardiac arrest. RECENT FINDINGS:In a recent study by Bobrow et al., gasping was identified in 33% of patients who arrested after the arrival of emergency medical services (EMS). Patients who arr...

journal_title：Current opinion in critical care

authors： Zuercher M,Ewy GA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The large variability in clinical practice plus the increasing awareness that certain processes of care are associated with improved medical outcomes has led to the development of clinical practice guidelines in serious infection. The evolution of guidelines and their impact on delivery of care in sev...

journal_title：Current opinion in critical care

authors： Cinel I,Dellinger RP

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Prerenal failure is used to designate a reversible form of acute renal dysfunction. However, the terminology encompasses several different conditions that vary considerably. The lack of a widely accepted definition for prerenal failure makes it impossible to determine the epidemiology, natural history...

journal_title：Current opinion in critical care

authors： Macedo E,Mehta RL

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment protocols targeting the rapid administration of appropriate antibiotics and hemodynamic support are now recognized as a key measure in the initial care of patients presenting with severe sepsis and septic shock. Strong evidence exists showing that time parameters, particularly in the emergen...

journal_title：Current opinion in critical care

authors： Nobre V,Sarasin FP,Pugin J

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the recent literature on the main aspects of perioperative acute kidney injury (AKI). RECENT FINDINGS:AKI occurs in 1 in every 10 surgical patients, with cardiac, orthopedic, and major abdominal surgeries being the procedures associated with the highest risk. Overall, comp...

journal_title：Current opinion in critical care

authors： Canet E,Bellomo R

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early rehabilitation of ICU patients has recently been identified as an important focus for interdisciplinary ICU teams. However, the amount of rehabilitation...

journal_title：Current opinion in critical care

authors： Gosselink R,Needham D,Hermans G

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Early prognostication in acute brain damage remains a challenge in the realm of critical care. There remains controversy over the most optimal methods that can be utilized to predict outcome. The utility of recently reported prognostic biomarkers and clinical methods will be reviewed. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Kalanuria AA,Geocadin RG

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:From an elderly patient's perspective, acute and chronic cognitive disturbances are among the most harmful complications that can occur following surgery. For elderly patients, these complications often mean the end of an independent life. This article focuses on this serious aspect, which is increasi...

journal_title：Current opinion in critical care

authors： Müller A,Lachmann G,Wolf A,Mörgeli R,Weiss B,Spies C

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-induced lung injury (VILI) can occur despite use of tidal volume (VT) limited to 6 ml/kg of predicted body weight, especially in patients with a smaller aerated compartment (i.e. the baby lung) in which, indeed, tidal ventilation takes place. Because respiratory system static compliance (CR...

journal_title：Current opinion in critical care

authors： Grieco DL,Chen L,Dres M,Brochard L

更新日期：2017-02-01 00:00:00

abstract：:The use of therapeutic moderate hypothermia for treating severe traumatic brain injury has been reported for more than 50 years. However, the most intense investigation of this treatment has occurred during the last 10 to 15 years. Virtually all preclinical studies have documented a robust treatment effect, not only i...

journal_title：Current opinion in critical care

authors： Marion DW

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

journal_title：Current opinion in critical care

authors： Edwards D,Nirmalan M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome (ARDS) is a multifaceted lung disease with no current effective therapy. Many clinical trials using conventional pharmacologic therapies have failed, suggesting the need to examine alternative approaches. Thus, attention has focused on the therapeutic potential of c...

journal_title：Current opinion in critical care

authors： Maron-Gutierrez T,Laffey JG,Pelosi P,Rocco PR

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Glutamine (GLN) is a versatile amino acid, long believed to have important implications in ICU and surgical patients. An extensive body of data examining GLN supplementation of TPN demonstrated a consistent signal of improved outcomes. However, recently signals of risk have come from two large-scale m...

journal_title：Current opinion in critical care

authors： Wischmeyer PE

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

journal_title：Current opinion in critical care

authors： Kortgen A,Recknagel P,Bauer M

更新日期：2010-04-01 00:00:00