Guidelines for severe infections: are they useful?

Abstract:

PURPOSE OF REVIEW:The large variability in clinical practice plus the increasing awareness that certain processes of care are associated with improved medical outcomes has led to the development of clinical practice guidelines in serious infection. The evolution of guidelines and their impact on delivery of care in severe infection is reviewed. RECENT FINDINGS:Guidelines development has centered around community- and hospital-acquired pneumonia as well as sepsis. The Institute of Healthcare Improvement has emerged as an international leader in changing healthcare professional behavior to be consistent with clinical recommendations in infection-related morbidity. These educational programs are designed to increase awareness of guidelines recommendations and to optimize their implementation. Change bundles are selected sets of interventions or processes distilled from evidence-based practice guidelines that are likely to improve outcome. As new evidence is published, and as experts ponder how the guidelines should best be expressed in the bundles, the bundles will be adapted to optimize their utility. SUMMARY:The change bundle approach to performance improvement (guidelines-based) is the key to change in practice. The Surviving Sepsis Campaign/Institute of Healthcare Improvement sepsis change bundles are an excellent example of progress along these lines.

journal_name

Curr Opin Crit Care

authors

Cinel I,Dellinger RP

doi

10.1097/01.ccx.0000244131.15484.4e

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

483-8

issue

5

eissn

1070-5295

issn

1531-7072

pii

00075198-200610000-00020

journal_volume

12

pub_type

杂志文章,评审
  • Weaning the patient: between protocols and physiology.

    abstract:PURPOSE OF REVIEW:Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review is to discuss new physiological and clinical insights in ventilator weaning tha...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章

    doi:10.1097/MCC.0000000000000790

    authors: Haaksma ME,Tuinman PR,Heunks L

    更新日期:2021-02-01 00:00:00

  • Blunt cerebrovascular trauma.

    abstract:PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32833ee8b4

    authors: Burlew CC,Biffl WL

    更新日期:2010-12-01 00:00:00

  • Esophageal pressure monitoring: why, when and how?

    abstract:PURPOSE OF REVIEW:Esophageal manometry has shown its usefulness to estimate transpulmonary pressure, that is lung stress, and the intensity of spontaneous effort in patients with acute respiratory distress syndrome. However, clinical uptake of esophageal manometry in ICU is still low. Thus, the purpose of review is to ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000494

    authors: Yoshida T,Brochard L

    更新日期:2018-06-01 00:00:00

  • The glutamine debate in surgery and critical care.

    abstract:PURPOSE OF REVIEW:Glutamine (GLN) is a versatile amino acid, long believed to have important implications in ICU and surgical patients. An extensive body of data examining GLN supplementation of TPN demonstrated a consistent signal of improved outcomes. However, recently signals of risk have come from two large-scale m...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000633

    authors: Wischmeyer PE

    更新日期:2019-08-01 00:00:00

  • Extracorporeal gas exchange.

    abstract:PURPOSE OF REVIEW:We report on recent advances and achievements on the use of extracorporeal gas exchange for long-term application in the therapy of critically ill patients with various forms of respiratory failure. RECENT FINDINGS:The most important results regarding the use of extracorporeal gas exchange are expect...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3283220e1f

    authors: Pesenti A,Zanella A,Patroniti N

    更新日期:2009-02-01 00:00:00

  • Fluid choices impact outcome in septic shock.

    abstract:PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000116

    authors: Douglas JJ,Walley KR

    更新日期:2014-08-01 00:00:00

  • Haemodynamic and ventilator management in patients following cardiac arrest.

    abstract:PURPOSE OF REVIEW:The purpose of this study is to review the recent literature describing how to assess and treat postcardiac arrest syndrome associated haemodynamics and manage oxygenation and ventilation derangements. RECENT FINDINGS:Postcardiac arrest syndrome is a well described entity that includes systemic ische...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000205

    authors: Topjian AA,Berg RA,Taccone FS

    更新日期:2015-06-01 00:00:00

  • Acute coagulopathy of trauma: mechanism, identification and effect.

    abstract:PURPOSE OF REVIEW:Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy. RECENT...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3282f1e78f

    authors: Brohi K,Cohen MJ,Davenport RA

    更新日期:2007-12-01 00:00:00

  • Coupling microcirculation to systemic hemodynamics.

    abstract:PURPOSE OF REVIEW:To discuss the role of microcirculatory abnormalities in critically ill patients and the link between systemic hemodynamics and microvascular perfusion. RECENT FINDINGS:Microcirculatory alterations have been repeatedly observed in patients with severe sepsis, but recent findings show that these also ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3283383621

    authors: De Backer D,Ortiz JA,Salgado D

    更新日期:2010-06-01 00:00:00

  • Recent developments in electronic alerts for acute kidney injury.

    abstract:PURPOSE OF REVIEW:Efforts to improve outcomes from acute kidney injury (AKI) have focussed on timely diagnosis and effective delivery of basic patient care. Electronic alerts (e-alerts) for AKI have attracted interest as a tool to facilitate this. Initial feasibility has already been demonstrated; this review will disc...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000245

    authors: Horne KL,Selby NM

    更新日期:2015-12-01 00:00:00

  • Technologic advances and program initiatives in public access defibrillation using automated external defibrillators.

    abstract::Widespread provision of early defibrillation following cardiac arrest holds major promise for improved survival from ventricular fibrillation. The critical element in predicting a successful outcome is the rapidity with which defibrillation is achieved. A worldwide awareness of this potential and its advocacy by such ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200106000-00002

    authors: White RD

    更新日期:2001-06-01 00:00:00

  • New ways to reduce unnecessary variation and improve outcomes in the intensive care unit.

    abstract::The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200108000-00015

    authors: Holcomb BW,Wheeler AP,Ely EW

    更新日期:2001-08-01 00:00:00

  • The epithelium in acute lung injury/acute respiratory distress syndrome.

    abstract:PURPOSE OF REVIEW:The mechanisms of epithelial injury in acute lung injury/acute respiratory distress syndrome have been of interest since the syndrome was first described. Cell therapies to replace injured epithelium are a futuristic dream; however, there is ongoing research to achieve this goal. We review research re...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3282f417a0

    authors: Gropper MA,Wiener-Kronish J

    更新日期:2008-02-01 00:00:00

  • Mental and physical disorders after ICU discharge.

    abstract:PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32833cc90b

    authors: Flaatten H

    更新日期:2010-10-01 00:00:00

  • Should we abandon corticosteroids during septic shock? No.

    abstract:PURPOSE OF REVIEW:With the publication of the results of the recent CORTICUS trial, stress ('low') doses of corticosteroids for the treatment of vasopressor-dependent septic shock in adults can still be considered controversial. The purpose of this narrative review is to elaborate the pros and cons of this treatment in...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328306a01d

    authors: Groeneveld AB,Molenaar N,Beishuizen B

    更新日期:2008-08-01 00:00:00

  • Hemodynamic monitoring by echocardiography in the ICU: the role of the new echo techniques.

    abstract:PURPOSE OF REVIEW:The present review will discuss the usefulness of ultrasound in the ICU in assessing hemodynamic instability in various critical care conditions. We will discuss how to interpret echocardiographic findings in critically ill patients including the physiological consequences of mechanical ventilation. ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32830e6d81

    authors: Salem R,Vallee F,Rusca M,Mebazaa A

    更新日期:2008-10-01 00:00:00

  • Current use of the pulmonary artery catheter.

    abstract:PURPOSE OF REVIEW:The pulmonary artery catheter is one of the most scrutinized monitors used in intensive care today. Pulmonary artery catheter use is declining due to limited demonstrated beneficial outcomes and the advancement of less invasive monitoring. This study discusses the current use of the pulmonary artery c...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32832b302b

    authors: Greenberg SB,Murphy GS,Vender JS

    更新日期:2009-06-01 00:00:00

  • Integrating palliative care in the ICU.

    abstract:PURPOSE OF REVIEW:Although providing palliative care in the ICU has become a priority, the success of different methods to integrate palliative care into the ICU has varied. This review examines the current evidence supporting the different models of palliative care delivery and highlights areas for future study. RECE...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000149

    authors: Hua M,Wunsch H

    更新日期:2014-12-01 00:00:00

  • Helicopter transport: help or hindrance?

    abstract:PURPOSE OF REVIEW:Traumatic injury continues to be a significant cause of morbidity and mortality in the year 2011. In addition, the healthcare expenditures and lost years of productivity represent significant economic cost to the affected individuals and their communities. Helicopters have been used to transport traum...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32834c5655

    authors: Plevin RE,Evans HL

    更新日期:2011-12-01 00:00:00

  • Uncertainty in end-of-life care.

    abstract:PURPOSE OF REVIEW:Uncertainty surrounding medical decision-making is particularly important during end-of-life decision-making. Doubts about the patient's best interests and prognostic accuracy may lead to conflict. RECENT FINDINGS:Many authors have suggested recently that medical attitudes to uncertainty need review....

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000030

    authors: Ridley S,Fisher M

    更新日期:2013-12-01 00:00:00

  • When and how should we do a tracheostomy?

    abstract::Tracheostomy is one of the most common surgical procedures in the intensive care unit. Since the introduction of percutaneous techniques, tracheostomy has become increasingly popular. The technique is relatively easy, and the early and late complication rates are relatively low.It is unknown at which moment tracheosto...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章

    doi:10.1097/00075198-200008000-00005

    authors: van Heurn LW

    更新日期:2000-08-01 00:00:00

  • Overview of ventilator-induced lung injury mechanisms.

    abstract:PURPOSE OF REVIEW:Mechanical ventilation is the main supportive therapy for patients with acute respiratory distress syndrome. As with any therapy, mechanical ventilation has side effects and may induce lung injury. This review will focus on stretch-dependent activation of alveolar epithelial and endothelial cells and ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200502000-00013

    authors: Lionetti V,Recchia FA,Ranieri VM

    更新日期:2005-02-01 00:00:00

  • Fluid removal in acute heart failure: diuretics versus devices.

    abstract:PURPOSE OF REVIEW:Fluid removal and relief of congestion are central to treatment of acute heart failure. Diuretics have been the decongestive mainstay but their known limitations have led to the exploration of alternative strategies. This review compares diuretics with ultrafiltration and examines the recent evidence ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000134

    authors: Krishnamoorthy A,Felker GM

    更新日期:2014-10-01 00:00:00

  • Novelties in pharmacological management of cardiopulmonary resuscitation.

    abstract:PURPOSE OF REVIEW:The ultimate goal of cardiopulmonary resuscitation is long-term neurologically intact survival. Despite numerous well-designed studies, the medications currently used in advanced cardiac life support have not demonstrated success in this regard. This review describes the novel therapeutics under inves...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328364d7b1

    authors: Bartos JA,Yannopoulos D

    更新日期:2013-10-01 00:00:00

  • Myocardial protection during resuscitation from cardiac arrest.

    abstract:PURPOSE OF REVIEW:Successful treatment of cardiac arrest requires that an electrically stable and mechanically competent cardiac activity be promptly reestablished. However, many interventions used to attempt to reestablish cardiac activity may also inflict additional myocardial injury and, in turn, compromise resuscit...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200306000-00005

    authors: Gazmuri RJ,Ayoub IM,Kolarova J

    更新日期:2003-06-01 00:00:00

  • Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?

    abstract:PURPOSE OF REVIEW:Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000367

    authors: Perkins ZB,Lendrum RA,Brohi K

    更新日期:2016-12-01 00:00:00

  • Effects of alcohol on the heart.

    abstract::Some evidence suggests that light to moderate alcohol consumption protects against cardiovascular diseases. However, this cardioprotective effect of alcohol consumption in adults is absent at the population level. Approximately 20 to 30% of patients admitted to a hospital are alcohol abusers. In medical practice, it i...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200110000-00004

    authors: Spies CD,Sander M,Stangl K,Fernandez-Sola J,Preedy VR,Rubin E,Andreasson S,Hanna EZ,Kox WJ

    更新日期:2001-10-01 00:00:00

  • Perioperative fluids: a clear road ahead?

    abstract:PURPOSE OF REVIEW:There is significant controversy for perioperative fluid management. This review discusses the evidence from clinical studies, basic research, and systematic reviews to provide a summary of the current best practice in this area. RECENT FINDINGS:Recent evidence has challenged the long-held contention...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3283632f1f

    authors: Peng ZY,Kellum JA

    更新日期:2013-08-01 00:00:00

  • High-frequency oscillatory ventilation: still a role?

    abstract:PURPOSE OF REVIEW:In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. This review provides an overview of these new clinical data and also explores new areas of investigation for HFOV in ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000387

    authors: Ng J,Ferguson ND

    更新日期:2017-04-01 00:00:00

  • Paralytics in critical care: not always the bad guy.

    abstract:PURPOSE OF REVIEW:The use of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS) and acute lung injury remains controversial, although frequent. This review analyzes the effects of NMBAs on thoracopulmonary mechanics, gas exchange, patient outcome and their potential advers...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/mcc.0b013e3283220e60

    authors: Forel JM,Roch A,Papazian L

    更新日期:2009-02-01 00:00:00