Should we abandon corticosteroids during septic shock? No.

abstract：:Reactive oxygen species are reactive, partially reduced derivatives of molecular oxygen (O 2 ). Important reactive oxygen species in biologic systems include superoxide radical anion, hydrogen peroxide, and hydroxyl radical. Closely related species include the hypohalous acids, particularly hypochlorous acid; chlorami...

journal_title：Current opinion in critical care

authors： Fink MP

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern technologies allow visualization of microcirculatory disorders. This review describes how the coagulatory inhibitors antithrombin and activated protein C (APC) can improve microcirculation in sepsis and transplantation. RECENT FINDINGS:The effects of antithrombin and APC on microcirculatory di...

journal_title：Current opinion in critical care

authors： Hoffmann JN,Fertmann JM,Jauch KW

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In the 1980s, we witnessed tremendous advances in trauma care including trauma system development, advanced trauma life support, damage control surgery and ICU resuscitation. As a result, patients who used to bleed to death in the operating room survived. However, many went on to develop multiple orga...

journal_title：Current opinion in critical care

authors： Gonzalez EA,Moore FA

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article will review the current state of our understanding of nephrotoxic medication-associated acute kidney injury (AKI) and provide strategies to reduce its impact. RECENT FINDINGS:Nephrotoxic medications contribute to a substantial proportion of AKI in hospitalized patients. The previo...

journal_title：Current opinion in critical care

authors： Goldstein SL

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Fluid removal and relief of congestion are central to treatment of acute heart failure. Diuretics have been the decongestive mainstay but their known limitations have led to the exploration of alternative strategies. This review compares diuretics with ultrafiltration and examines the recent evidence ...

journal_title：Current opinion in critical care

authors： Krishnamoorthy A,Felker GM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Part II of this review gives an overview of the different maternal cardiac problems during pregnancy and their management, and developments over recent years. RECENT FINDINGS:Many studies published over the last 5 years provided new insights on different cardiac diseases in pregnancy. Publications di...

journal_title：Current opinion in critical care

authors： van Mook WN,Peeters L

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the progress made over the past 20 years in the treatment of septic shock, mortality remains high. Microcirculatory disorders raise considerable interest aiming to improve the understanding of the physiopathology of septic shock and its management. RECENT FINDINGS:Numerous experimental and cl...

journal_title：Current opinion in critical care

authors： Ait-Oufella H,Bourcier S,Lehoux S,Guidet B

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Increased use of advanced life-sustaining measures in patients with poor long-term expectations secondary to more chronic organ dysfunctions, comorbidities and/or a poor quality of life has become a worrying trend over the last decade. This can lead to futile, disproportionate or inappropriate care in...

journal_title：Current opinion in critical care

authors： Kompanje EJ,Piers RD,Benoit DD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Stress ulcer prophylaxis (SUP) is considered standard of care in the majority of critically ill patients in the ICU. In this review, we will present the current evidence for the use of SUP in ICU patients, including data on the prevalence of gastrointestinal bleeding and the balance between benefits a...

journal_title：Current opinion in critical care

authors： Krag M,Perner A,Møller MH

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review will discuss the usefulness of ultrasound in the ICU in assessing hemodynamic instability in various critical care conditions. We will discuss how to interpret echocardiographic findings in critically ill patients including the physiological consequences of mechanical ventilation. ...

journal_title：Current opinion in critical care

authors： Salem R,Vallee F,Rusca M,Mebazaa A

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current knowledge about clinical and microbiological diagnosis of nonventilated hospital-acquired pneumonia (NV-HAP). RECENT FINDINGS:NV-HAP is emerging as a new challenge for clinicians, particularly because VAP incidence has been decreasing. The clinical diagnosis of NV-HAP uses the...

journal_title：Current opinion in critical care

authors： Ranzani OT,De Pascale G,Park M

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute liver failure (ALF) is associated with significant mortality. Although specific therapies may be available, the evidence base for these and for many aspects of supportive therapy has been slow to emerge. Liver transplantation continues to be a cornerstone of treatment, and the management of ALF,...

journal_title：Current opinion in critical care

authors： Willars C

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current concepts in perioperative pulmonary management. RECENT FINDINGS:Preoperative risk assessment tools for perioperative pulmonary complications (POPCs) are evolving for both children and adults. Intraoperative management strategies have a demonstrable effect on outcomes. Lat...

journal_title：Current opinion in critical care

authors： Johnson DC,Kaplan LJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Efforts to improve outcomes from acute kidney injury (AKI) have focussed on timely diagnosis and effective delivery of basic patient care. Electronic alerts (e-alerts) for AKI have attracted interest as a tool to facilitate this. Initial feasibility has already been demonstrated; this review will disc...

journal_title：Current opinion in critical care

authors： Horne KL,Selby NM

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Esophageal manometry has shown its usefulness to estimate transpulmonary pressure, that is lung stress, and the intensity of spontaneous effort in patients with acute respiratory distress syndrome. However, clinical uptake of esophageal manometry in ICU is still low. Thus, the purpose of review is to ...

journal_title：Current opinion in critical care

authors： Yoshida T,Brochard L

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：:Cardiac arrest survival rates remain low despite increased access to advanced cardiac life support. Survival from cardiac arrest is, at least in part, related to the perfusion pressures and blood flow achieved during cardiopulmonary resuscitation (CPR). A number of alternative CPR devices have been developed that aim ...

journal_title：Current opinion in critical care

authors： Smith T

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome (ARDS) is a multifaceted lung disease with no current effective therapy. Many clinical trials using conventional pharmacologic therapies have failed, suggesting the need to examine alternative approaches. Thus, attention has focused on the therapeutic potential of c...

journal_title：Current opinion in critical care

authors： Maron-Gutierrez T,Laffey JG,Pelosi P,Rocco PR

更新日期：2014-02-01 00:00:00

abstract：:The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

journal_title：Current opinion in critical care

authors： Holcomb BW,Wheeler AP,Ely EW

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Securing the airway to provide sufficient oxygenation and ventilation is of paramount importance in the management of all types of emergency patients. Particularly in severely injured patients, strategies should be adapted according to useful recent literature findings. RECENT FINDINGS:The role of ou...

journal_title：Current opinion in critical care

authors： Beckers SK,Brokmann JC,Rossaint R

更新日期：2014-12-01 00:00:00

abstract：:Some evidence suggests that light to moderate alcohol consumption protects against cardiovascular diseases. However, this cardioprotective effect of alcohol consumption in adults is absent at the population level. Approximately 20 to 30% of patients admitted to a hospital are alcohol abusers. In medical practice, it i...

journal_title：Current opinion in critical care

authors： Spies CD,Sander M,Stangl K,Fernandez-Sola J,Preedy VR,Rubin E,Andreasson S,Hanna EZ,Kox WJ

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Energy dysfunction is increasingly recognized as a key factor in the pathogenesis of acute brain injury (ABI). This one characterized by a high metabolic rate and nitrogen loss is often associated with an undernutrition support. We review the metabolism evolution and nutritional status in brain injure...

journal_title：Current opinion in critical care

authors： Quintard H,Ichai C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple factors influence the dependability of intensive care provision. The management of a group of unstable, critically ill patients requires focused attention from the clinical team. Medical simulation is an important tool to improve safety and team work within the ICU. RECENT FINDINGS:The criti...

journal_title：Current opinion in critical care

authors： Fox-Robichaud AE,Nimmo GR

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of r...

journal_title：Current opinion in critical care

authors： Cantón R,Gijón D,Ruiz-Garbajosa P

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Continuous electroencephalography (cEEG) is being used more frequently in intensive care units to detect epileptic activity and ischemia. This review analyzes clinical applications and limitations of cEEG as a routine neuromonitoring tool. RECENT FINDINGS:cEEG is primarily used to detect nonconvulsiv...

journal_title：Current opinion in critical care

authors： Kurtz P,Hanafy KA,Claassen J

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The gut has long been hypothesized to be the 'motor' of multiple organ dysfunction syndrome. This review serves as an update on new data elucidating the role of the gut as the propagator of organ failure in critical illness. RECENT FINDINGS:Under basal conditions, the gut absorbs nutrients and serves...

journal_title：Current opinion in critical care

authors： Meng M,Klingensmith NJ,Coopersmith CM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Status epilepticus has a high morbidity and mortality. There are little definitive data to guide management; however, new recent data continue to improve understanding of management options of status epilepticus. This review examines recent advancements regarding the critical care management of status...

journal_title：Current opinion in critical care

authors： Bauerschmidt A,Martin A,Claassen J

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Fried E,Weissman C,Sprung C

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The comparison of morbidity, mortality, and length-of-stay outcomes in patients receiving critical care requires adjustment based on their presenting illness. These adjustments are made with severity-of-illness models. These models must be periodically updated to reflect current medical practices. Thi...

journal_title：Current opinion in critical care

authors： Higgins TL,Teres D,Nathanson B

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

journal_title：Current opinion in critical care

authors： Flaatten H

更新日期：2010-10-01 00:00:00