The epithelium in acute lung injury/acute respiratory distress syndrome.

abstract：PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...

journal_title：Current opinion in critical care

authors： Burlew CC,Biffl WL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Nutritional status and nutrient delivery during critical illness impact clinical outcomes. We have reviewed recent studies that may guide best practices regarding nutrition therapy in critically ill children. RECENT FINDINGS:Malnutrition is prevalent in the pediatric ICU population, and is associated...

journal_title：Current opinion in critical care

authors： Martinez EE,Mehta NM

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:There is growing evidence that bone health is impacted during and after critical illness in multiple ways. In this review, we provide a practical update on postcritical care bone loss with an insight on identification of persons at risk, prevention and treatment strategies. RECENT FINDINGS:Critical i...

journal_title：Current opinion in critical care

authors： Rousseau AF,Kerschan-Schindl K,Scherkl M,Amrein K

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize clinical evidence for intraoperative ventilation settings, which could protect against postoperative pulmonary complications (PPCs) in surgical patients with uninjured lungs. RECENT FINDINGS:There is convincing evidence for protection against PPCs by low tidal volumes: benefit was found ...

journal_title：Current opinion in critical care

authors： Schultz MJ,Abreu MG,Pelosi P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Tissue hypoperfusion is a common pathophysiologic process leading to multiple-organ dysfunction and death. An important goal of hemodynamic monitoring is the early detection of inadequate tissue perfusion and oxygenation. The use of simple, noninvasive monitoring techniques has the advantage of facili...

journal_title：Current opinion in critical care

authors： Creteur J

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of r...

journal_title：Current opinion in critical care

authors： Cantón R,Gijón D,Ruiz-Garbajosa P

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review is to discuss new physiological and clinical insights in ventilator weaning tha...

journal_title：Current opinion in critical care

authors： Haaksma ME,Tuinman PR,Heunks L

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the clear rationale for evidence-based medicine (EvBM) in the challenging realms of resuscitation research, yet also provide case examples in which even the well designed, multicentered randomized clinical trial may have had unrecognized limitations, and thus misleading results. This is whe...

journal_title：Current opinion in critical care

authors： Pepe PE,Aufderheide TP

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To outline evidence that suggests increased intestinal epithelial apoptosis (programmed cell death) plays an important role in critical illness of infectious and noninfectious origin. RECENT FINDINGS:Both human and animal studies demonstrate that the gut epithelium has increased levels of cellular de...

journal_title：Current opinion in critical care

authors： Husain KD,Coopersmith CM

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

journal_title：Current opinion in critical care

authors： Douglas JJ,Walley KR

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

journal_title：Current opinion in critical care

authors： Edwards D,Nirmalan M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The large variability in clinical practice plus the increasing awareness that certain processes of care are associated with improved medical outcomes has led to the development of clinical practice guidelines in serious infection. The evolution of guidelines and their impact on delivery of care in sev...

journal_title：Current opinion in critical care

authors： Cinel I,Dellinger RP

更新日期：2006-10-01 00:00:00

abstract：:Widespread provision of early defibrillation following cardiac arrest holds major promise for improved survival from ventricular fibrillation. The critical element in predicting a successful outcome is the rapidity with which defibrillation is achieved. A worldwide awareness of this potential and its advocacy by such ...

journal_title：Current opinion in critical care

authors： White RD

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review intends to summarize the recent findings regarding the presence of increased oxidative stress in critically ill patients and its potential pathophysiologic role, as well as the results of recent clinical trials of antioxidant therapies. RECENT FINDINGS:Several lines of evidence confirm th...

journal_title：Current opinion in critical care

authors： Lovat R,Preiser JC

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-induced lung injury (VILI) can occur despite use of tidal volume (VT) limited to 6 ml/kg of predicted body weight, especially in patients with a smaller aerated compartment (i.e. the baby lung) in which, indeed, tidal ventilation takes place. Because respiratory system static compliance (CR...

journal_title：Current opinion in critical care

authors： Grieco DL,Chen L,Dres M,Brochard L

更新日期：2017-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple factors influence the dependability of intensive care provision. The management of a group of unstable, critically ill patients requires focused attention from the clinical team. Medical simulation is an important tool to improve safety and team work within the ICU. RECENT FINDINGS:The criti...

journal_title：Current opinion in critical care

authors： Fox-Robichaud AE,Nimmo GR

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory di...

journal_title：Current opinion in critical care

authors： Rocco PR,Zin WA

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The risk of adverse outcome in patients undergoing major surgery is affected both by cardiorespiratory fitness, and the presence and severity of comorbidities. Accurate risk stratification is essential for the identification of patients who may benefit from specific perioperative management strategies...

journal_title：Current opinion in critical care

authors： Moonesinghe SR,Mythen MG,Grocott MP

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute liver failure (ALF) is associated with significant mortality. Although specific therapies may be available, the evidence base for these and for many aspects of supportive therapy has been slow to emerge. Liver transplantation continues to be a cornerstone of treatment, and the management of ALF,...

journal_title：Current opinion in critical care

authors： Willars C

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current knowledge about clinical and microbiological diagnosis of nonventilated hospital-acquired pneumonia (NV-HAP). RECENT FINDINGS:NV-HAP is emerging as a new challenge for clinicians, particularly because VAP incidence has been decreasing. The clinical diagnosis of NV-HAP uses the...

journal_title：Current opinion in critical care

authors： Ranzani OT,De Pascale G,Park M

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS) and acute lung injury remains controversial, although frequent. This review analyzes the effects of NMBAs on thoracopulmonary mechanics, gas exchange, patient outcome and their potential advers...

journal_title：Current opinion in critical care

authors： Forel JM,Roch A,Papazian L

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Status epilepticus is a neurological emergency associated with high morbidity and mortality. There is a lack of robust data to guide the management of this neurological emergency beyond the initial treatment. This review examines recent literature on treatment considerations including the choice of co...

journal_title：Current opinion in critical care

authors： Der-Nigoghossian C,Rubinos C,Alkhachroum A,Claassen J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The scope of this review is to describe what is known about injury outcomes and the principles by which they can be improved by acute phase interventions. Assessing which outcomes matter to trauma patients is important both for the evaluation of existing and novel acute interventions and to assess the...

journal_title：Current opinion in critical care

authors： Brohi K,Cole E,Hoffman K

更新日期：2011-10-01 00:00:00

abstract：:This review discusses the myocardial protective property of the insulin/glucose-insulin-potassium regimen and the mechanisms involved in this beneficial action. Several recent studies suggest that insulin not only is useful to control hyperglycemia and maintain glucose homeostasis but also may have the unique property...

journal_title：Current opinion in critical care

authors： Das UN

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To investigate the impact of critical illness polyneuropathy and critical illness myopathy on short-term and long-term patient outcome. RECENT FINDINGS:In the acute-care setting, critical illness polyneuropathy and critical illness myopathy are important causes of acute paralysis in critically ill co...

journal_title：Current opinion in critical care

authors： Latronico N,Shehu I,Seghelini E

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the review is to summarize and discuss recent research regarding the role of mechanical ventilation in producing weakness and atrophy of the diaphragm in critically ill patients, an entity termed ventilator-induced diaphragmatic dysfunction (VIDD). RECENT FINDINGS:Severe weakness of th...

journal_title：Current opinion in critical care

authors： Petrof BJ,Hussain SN

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent and serious event associated with a high rate of complications, with an increased risk of progression to multiple organ dysfunction and excessive 'attributable' mortality. AKI affects all physiologic functions and organ systems with interrelated mechanisms, incl...

journal_title：Current opinion in critical care

authors： Druml W

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantable cardioverter-defibrillator (ICD) implantation is the standard of care for secondary prevention in patients with previous cardiac arrest and for primary prevention in appropriately selected patients with cardiomyopathy. However, ICD therapies and the arrhythmias that trigger these therapies...

journal_title：Current opinion in critical care

authors： Bradfield JS,Buch E,Shivkumar K

更新日期：2012-10-01 00:00:00