Weaning the patient: between protocols and physiology.

abstract：PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

journal_title：Current opinion in critical care

authors： Kortgen A,Recknagel P,Bauer M

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Nutritional status and nutrient delivery during critical illness impact clinical outcomes. We have reviewed recent studies that may guide best practices regarding nutrition therapy in critically ill children. RECENT FINDINGS:Malnutrition is prevalent in the pediatric ICU population, and is associated...

journal_title：Current opinion in critical care

authors： Martinez EE,Mehta NM

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The mechanisms of epithelial injury in acute lung injury/acute respiratory distress syndrome have been of interest since the syndrome was first described. Cell therapies to replace injured epithelium are a futuristic dream; however, there is ongoing research to achieve this goal. We review research re...

journal_title：Current opinion in critical care

authors： Gropper MA,Wiener-Kronish J

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Part II of this review gives an overview of the different maternal cardiac problems during pregnancy and their management, and developments over recent years. RECENT FINDINGS:Many studies published over the last 5 years provided new insights on different cardiac diseases in pregnancy. Publications di...

journal_title：Current opinion in critical care

authors： van Mook WN,Peeters L

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is correlation between quality of bystander cardiopulmonary resuscitation and patient survival. Recent developments in defibrillator technology enable recording of cardiopulmonary resuscitation quality, and have shown quality of professional cardiopulmonary resuscitation far from guidelines' lev...

journal_title：Current opinion in critical care

authors： Steen PA,Kramer-Johansen J

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Early prognostication in acute brain damage remains a challenge in the realm of critical care. There remains controversy over the most optimal methods that can be utilized to predict outcome. The utility of recently reported prognostic biomarkers and clinical methods will be reviewed. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Kalanuria AA,Geocadin RG

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the review is to summarize and discuss recent research regarding the role of mechanical ventilation in producing weakness and atrophy of the diaphragm in critically ill patients, an entity termed ventilator-induced diaphragmatic dysfunction (VIDD). RECENT FINDINGS:Severe weakness of th...

journal_title：Current opinion in critical care

authors： Petrof BJ,Hussain SN

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy. RECENT...

journal_title：Current opinion in critical care

authors： Brohi K,Cohen MJ,Davenport RA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:There is growing evidence that bone health is impacted during and after critical illness in multiple ways. In this review, we provide a practical update on postcritical care bone loss with an insight on identification of persons at risk, prevention and treatment strategies. RECENT FINDINGS:Critical i...

journal_title：Current opinion in critical care

authors： Rousseau AF,Kerschan-Schindl K,Scherkl M,Amrein K

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Tissue hypoperfusion is a common pathophysiologic process leading to multiple-organ dysfunction and death. An important goal of hemodynamic monitoring is the early detection of inadequate tissue perfusion and oxygenation. The use of simple, noninvasive monitoring techniques has the advantage of facili...

journal_title：Current opinion in critical care

authors： Creteur J

更新日期：2008-06-01 00:00:00

abstract：:Positive-pressure ventilation alters stroke volume by transiently increasing intrathoracic pressure and thereby decreasing preload. This phasic variation in stroke volume results in a cyclic fluctuation in arterial pressure with a phase length equal to the respiratory rate. Measuring ventilation-induced arterial press...

journal_title：Current opinion in critical care

authors： Gunn SR,Pinsky MR

更新日期：2001-06-01 00:00:00

abstract：:Tracheostomy is one of the most common surgical procedures in the intensive care unit. Since the introduction of percutaneous techniques, tracheostomy has become increasingly popular. The technique is relatively easy, and the early and late complication rates are relatively low.It is unknown at which moment tracheosto...

journal_title：Current opinion in critical care

authors： van Heurn LW

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and examine the efficacy of recently described medical and surgical interventions after acute ischaemic stroke using data from well conducted, clinical trials and systematic reviews. This review will consider recently published or updated articles. RECENT FINDINGS:As therapeutic options evo...

journal_title：Current opinion in critical care

authors： Andrews PJ

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

journal_title：Current opinion in critical care

authors： Edwards D,Nirmalan M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The risk of adverse outcome in patients undergoing major surgery is affected both by cardiorespiratory fitness, and the presence and severity of comorbidities. Accurate risk stratification is essential for the identification of patients who may benefit from specific perioperative management strategies...

journal_title：Current opinion in critical care

authors： Moonesinghe SR,Mythen MG,Grocott MP

更新日期：2009-08-01 00:00:00

abstract：:The purpose of this report is to provide information regarding preparation for disaster management from the perspective of ICU physicians. Both a framework toward ICU preparation for disaster management and a guide to the relevant literature are presented. Our objective is to show that the understanding of disaster pr...

journal_title：Current opinion in critical care

authors： Roccaforte JD,Cushman JG

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guideline...

journal_title：Current opinion in critical care

authors： Oddo M,Friberg H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is commonplace in most ICUs. In many cases the cause is believed to be multifactorial with sepsis being a major component. However, occasionally intrinsic renal disease will present to the ICU and as such critical care practitioners should be aware of this possibility and the...

journal_title：Current opinion in critical care

authors： Amery CE,Forni LG

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory di...

journal_title：Current opinion in critical care

authors： Rocco PR,Zin WA

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a summary of the recent literature on extracorporeal membrane oxygenation (ECMO) in adults with severe acute respiratory distress syndrome (ARDS), focusing on advances in equipment, current conventional and unconventional indications, complications, and future applications. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Leligdowicz A,Fan E

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients. RECENT FINDINGS:The choice of perioperative haemodynamic monito...

journal_title：Current opinion in critical care

authors： Kirov MY,Kuzkov VV,Molnar Z

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite decades of advances in prehospital and in-hospital medical care, patients with out-of-hospital cardiac arrest continue to have poor neurologic and cardiac function following otherwise successful resuscitation. This review examines the mechanisms and therapeutic strategies currently under devel...

journal_title：Current opinion in critical care

authors： Bartos JA,Debaty G,Matsuura T,Yannopoulos D

更新日期：2014-06-01 00:00:00

abstract：:Cardiac arrest survival rates remain low despite increased access to advanced cardiac life support. Survival from cardiac arrest is, at least in part, related to the perfusion pressures and blood flow achieved during cardiopulmonary resuscitation (CPR). A number of alternative CPR devices have been developed that aim ...

journal_title：Current opinion in critical care

authors： Smith T

更新日期：2002-06-01 00:00:00

abstract：:The introduction of mechanical ventilation in the intensive care unit environment had the merit of putting a potent life-saving tool in the physicians' hands in a number of situations; however, like most sophisticated technologies, it can cause severe side effects and eventually increase mortality if improperly applie...

journal_title：Current opinion in critical care

authors： Appendini L,Confalonieri M,Rossi A

更新日期：2001-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent finding in critically ill patients and is associated with adverse outcomes. With the purpose of improving outcome of AKI, the Kidney Disease: Improving Global Outcomes (KDIGO) group, a group of experts in critical care nephrology, has presented a set of guidelin...

journal_title：Current opinion in critical care

authors： Hoste EA,De Corte W

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Energy dysfunction is increasingly recognized as a key factor in the pathogenesis of acute brain injury (ABI). This one characterized by a high metabolic rate and nitrogen loss is often associated with an undernutrition support. We review the metabolism evolution and nutritional status in brain injure...

journal_title：Current opinion in critical care

authors： Quintard H,Ichai C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The large variability in clinical practice plus the increasing awareness that certain processes of care are associated with improved medical outcomes has led to the development of clinical practice guidelines in serious infection. The evolution of guidelines and their impact on delivery of care in sev...

journal_title：Current opinion in critical care

authors： Cinel I,Dellinger RP

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac arrest is one of the most challenging disease processes to study with clinical trials due to the emergent and unpredictable nature of these events and complexity of the patient population. In recent years, there has been a major push to complete more large, multicentre trials. In many cases, h...

journal_title：Current opinion in critical care

authors： Berg KM

更新日期：2020-12-01 00:00:00