Clinical relevance of monitoring respiratory mechanics in the ventilator-supported patient: an update (1995-2000).

abstract：:Successes in machine-based extracorporeal support for different organ functions stimulated research in the field of liver support approximately 50 years ago. Initial failure to improve outcome using detoxification methods like dialysis, blood and plasma exchange, or plasmapheresis over sorbents fueled interest in biol...

journal_title：Current opinion in critical care

authors： Mitzner SR,Stange J,Peszynski P,Klammt S

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Progress has been made in our understanding of gut dysfunction in critical illness. This review will outline new findings and give perspectives based on previous knowledge and concurrent advances in nutrition. RECENT FINDINGS:The relationship between gut dysfunction and poor outcomes in critical illn...

journal_title：Current opinion in critical care

authors： Chapple LS,Plummer MP,Chapman MJ

更新日期：2021-01-21 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobials are very commonly used drugs in the intensive care setting. Extensive research has been conducted in recent years to describe their pharmacokinetics/pharmacodynamics in order to maximize the pharmacological benefit and patient outcome. Translating these new findings into clinical practi...

journal_title：Current opinion in critical care

authors： Tsai D,Lipman J,Roberts JA

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Fluid removal and relief of congestion are central to treatment of acute heart failure. Diuretics have been the decongestive mainstay but their known limitations have led to the exploration of alternative strategies. This review compares diuretics with ultrafiltration and examines the recent evidence ...

journal_title：Current opinion in critical care

authors： Krishnamoorthy A,Felker GM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Energy dysfunction is increasingly recognized as a key factor in the pathogenesis of acute brain injury (ABI). This one characterized by a high metabolic rate and nitrogen loss is often associated with an undernutrition support. We review the metabolism evolution and nutritional status in brain injure...

journal_title：Current opinion in critical care

authors： Quintard H,Ichai C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The ultimate goal of cardiopulmonary resuscitation is long-term neurologically intact survival. Despite numerous well-designed studies, the medications currently used in advanced cardiac life support have not demonstrated success in this regard. This review describes the novel therapeutics under inves...

journal_title：Current opinion in critical care

authors： Bartos JA,Yannopoulos D

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasin...

journal_title：Current opinion in critical care

authors： Festic E,Kor DJ,Gajic O

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The risk of adverse outcome in patients undergoing major surgery is affected both by cardiorespiratory fitness, and the presence and severity of comorbidities. Accurate risk stratification is essential for the identification of patients who may benefit from specific perioperative management strategies...

journal_title：Current opinion in critical care

authors： Moonesinghe SR,Mythen MG,Grocott MP

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:A significant number of patients hospitalized with heart failure are malnourished. Depletion of micronutrients, which is known to occur in heart failure for a variety of reasons, may contribute to myocardial abnormalities noted in heart failure. In this review, we focus on nutritional supplementation ...

journal_title：Current opinion in critical care

authors： Sarma S,Gheorghiade M

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

journal_title：Current opinion in critical care

authors： Douglas JJ,Walley KR

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review will discuss the usefulness of ultrasound in the ICU in assessing hemodynamic instability in various critical care conditions. We will discuss how to interpret echocardiographic findings in critically ill patients including the physiological consequences of mechanical ventilation. ...

journal_title：Current opinion in critical care

authors： Salem R,Vallee F,Rusca M,Mebazaa A

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Selenium is a trace element essential to human health. Critical illness is associated with the generation of oxygen free radicals resulting in a condition of oxidative stress. Supplementing critically ill patients with antioxidant nutrients may improve survival. Selenium levels can be low due to redis...

journal_title：Current opinion in critical care

authors： Geoghegan M,McAuley D,Eaton S,Powell-Tuck J

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Care surrounding end-of-life has become a major topic in the intensive care medicine literature. Cultural and regional variations are associated with transatlantic debates about decisions to forego life-sustaining therapies and lead to recent international statements. The aim of this review is to prov...

journal_title：Current opinion in critical care

authors： Fassier T,Lautrette A,Ciroldi M,Azoulay E

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Survivorship or addressing impaired quality of life (QoL) in ICU survivors has been named 'the defining challenge of critical care' for this century to address this challenge; in addition to optimal nutrition, we must learn to employ targeted metabolic/muscle assessment techniques and utilize structur...

journal_title：Current opinion in critical care

authors： Molinger J,Pastva AM,Whittle J,Wischmeyer PE

更新日期：2020-08-01 00:00:00

abstract：:Increased knowledge of the mechanisms that determine respiratory failure has led to the development of new technologies aimed at improving ventilatory treatment. Proportional assist ventilation and neurally adjusted ventilatory assist have been designed with the goal of improving patient-ventilator interaction by matc...

journal_title：Current opinion in critical care

authors： Navalesi P,Costa R

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the clear rationale for evidence-based medicine (EvBM) in the challenging realms of resuscitation research, yet also provide case examples in which even the well designed, multicentered randomized clinical trial may have had unrecognized limitations, and thus misleading results. This is whe...

journal_title：Current opinion in critical care

authors： Pepe PE,Aufderheide TP

更新日期：2017-06-01 00:00:00

abstract：:Some evidence suggests that light to moderate alcohol consumption protects against cardiovascular diseases. However, this cardioprotective effect of alcohol consumption in adults is absent at the population level. Approximately 20 to 30% of patients admitted to a hospital are alcohol abusers. In medical practice, it i...

journal_title：Current opinion in critical care

authors： Spies CD,Sander M,Stangl K,Fernandez-Sola J,Preedy VR,Rubin E,Andreasson S,Hanna EZ,Kox WJ

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

journal_title：Current opinion in critical care

authors： Kortgen A,Recknagel P,Bauer M

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple factors influence the dependability of intensive care provision. The management of a group of unstable, critically ill patients requires focused attention from the clinical team. Medical simulation is an important tool to improve safety and team work within the ICU. RECENT FINDINGS:The criti...

journal_title：Current opinion in critical care

authors： Fox-Robichaud AE,Nimmo GR

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of the invasive monitoring techniques pulmonary artery catheter (PAC) and transpulmonary thermodilution (TPD) for cardiopulmonary monitoring in the critically ill patient. RECENT FINDINGS:Characterization of the nature of hemodynamic alterations and hemodynamic optimization can be...

journal_title：Current opinion in critical care

authors： De Backer D,Fagnoul D,Herpain A

更新日期：2013-06-01 00:00:00

abstract：:Cardiac arrest survival rates remain low despite increased access to advanced cardiac life support. Survival from cardiac arrest is, at least in part, related to the perfusion pressures and blood flow achieved during cardiopulmonary resuscitation (CPR). A number of alternative CPR devices have been developed that aim ...

journal_title：Current opinion in critical care

authors： Smith T

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of microcirculatory abnormalities in critically ill patients and the link between systemic hemodynamics and microvascular perfusion. RECENT FINDINGS:Microcirculatory alterations have been repeatedly observed in patients with severe sepsis, but recent findings show that these also ...

journal_title：Current opinion in critical care

authors： De Backer D,Ortiz JA,Salgado D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to review the prevalence and significance of gasping in patients experiencing cardiac arrest. RECENT FINDINGS:In a recent study by Bobrow et al., gasping was identified in 33% of patients who arrested after the arrival of emergency medical services (EMS). Patients who arr...

journal_title：Current opinion in critical care

authors： Zuercher M,Ewy GA

更新日期：2009-06-01 00:00:00

abstract：:Positive-pressure ventilation alters stroke volume by transiently increasing intrathoracic pressure and thereby decreasing preload. This phasic variation in stroke volume results in a cyclic fluctuation in arterial pressure with a phase length equal to the respiratory rate. Measuring ventilation-induced arterial press...

journal_title：Current opinion in critical care

authors： Gunn SR,Pinsky MR

更新日期：2001-06-01 00:00:00

abstract：:The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

journal_title：Current opinion in critical care

authors： Holcomb BW,Wheeler AP,Ely EW

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Conventional intermittent hemodialysis and continuous veno-venous hemofiltration are the opposite poles of current treatment modalities for patients with acute renal failure in the intensive care unit. Because both intermittent and continuous renal replacement techniques have several disadvantages, al...

journal_title：Current opinion in critical care

authors： Fliser D,Kielstein JT

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current knowledge about clinical and microbiological diagnosis of nonventilated hospital-acquired pneumonia (NV-HAP). RECENT FINDINGS:NV-HAP is emerging as a new challenge for clinicians, particularly because VAP incidence has been decreasing. The clinical diagnosis of NV-HAP uses the...

journal_title：Current opinion in critical care

authors： Ranzani OT,De Pascale G,Park M

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins are effective lipid-lowering agents used extensively in medical practice. This review summarizes the evidence for statin treatment of cardiovascular patients in the intensive care unit and briefly discusses the role of statins in prevention and treatment of sepsis as a potential future applica...

journal_title：Current opinion in critical care

authors： Merx MW,Weber C

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients. RECENT FINDINGS:The choice of perioperative haemodynamic monito...

journal_title：Current opinion in critical care

authors： Kirov MY,Kuzkov VV,Molnar Z

更新日期：2010-08-01 00:00:00