Should we use driving pressure to set tidal volume?

abstract：PURPOSE OF REVIEW:Selenium is a trace element essential to human health. Critical illness is associated with the generation of oxygen free radicals resulting in a condition of oxidative stress. Supplementing critically ill patients with antioxidant nutrients may improve survival. Selenium levels can be low due to redis...

journal_title：Current opinion in critical care

authors： Geoghegan M,McAuley D,Eaton S,Powell-Tuck J

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the progress of the multicenter, randomized, controlled trial of corticosteroids after significant head injury (CRASH). RECENT FINDINGS:After a successful pilot phase, the main phase of the CRASH Trial began in March 2001. By June 2002, 107 hospitals from 31 countries were par...

journal_title：Current opinion in critical care

authors： MRC CRASH Trial National Coordinators.

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Care of the injured patient is a dynamic process. Hemorrhage remains the primary cause of preventable death after trauma. Rapid and effective early care can improve survival and outcomes. Emerging therapies to address traumatic hemorrhage will be discussed. RECENT FINDINGS:Current concepts in trauma ...

journal_title：Current opinion in critical care

authors： Sambasivan CN,Schreiber MA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To investigate the impact of critical illness polyneuropathy and critical illness myopathy on short-term and long-term patient outcome. RECENT FINDINGS:In the acute-care setting, critical illness polyneuropathy and critical illness myopathy are important causes of acute paralysis in critically ill co...

journal_title：Current opinion in critical care

authors： Latronico N,Shehu I,Seghelini E

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:End-of-life care and communication deficits are important sources of conflicts within ICU teams and with patients or families. This narrative review describes recent studies on how to improve palliative care and surrogate decision-making in ICUs and compares the results with previously published liter...

journal_title：Current opinion in critical care

authors： Wiedermann CJ,Lehner GF,Joannidis M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe and put into context recent conceptual advances regarding the relationship of energy load and power to ventilator-induced lung injury (VILI). RECENT FINDINGS:Investigative emphasis regarding VILI has almost exclusively centered on the static characteristics of the individual tidal cycle -...

journal_title：Current opinion in critical care

authors： Marini JJ

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Point-of-care ultrasound (POCUS) is commonly used during cardiac arrest to screen for potential causes and to inform termination of resuscitation. However, unique biases and limitations in diagnostic and prognostic test accuracy studies lead to potential for misinterpretation. The present review highl...

journal_title：Current opinion in critical care

authors： Reynolds JC,Del Rios M

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the results of case series and trials which evaluated venovenous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. Potential indications of the technique in this setting are discussed. RECENT FINDINGS:Major technological improvements in extracorporeal ...

journal_title：Current opinion in critical care

authors： Combes A,Bréchot N,Luyt CE,Schmidt M

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients. RECENT FINDINGS:The choice of perioperative haemodynamic monito...

journal_title：Current opinion in critical care

authors： Kirov MY,Kuzkov VV,Molnar Z

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

journal_title：Current opinion in critical care

authors： Flaatten H

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of re...

journal_title：Current opinion in critical care

authors： Pineton de Chambrun M,Bréchot N,Combes A

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Shock occurs because of a failure to deliver adequate oxygen to meet the metabolic demands of the body resulting in metabolic acidosis, inflammation, and coagulopathy. Resuscitation is the process of treating shock in an attempt to restore normal physiology. Various hemodynamic, metabolic, and regiona...

journal_title：Current opinion in critical care

authors： Connelly CR,Schreiber MA

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review intends to summarize the recent findings regarding the presence of increased oxidative stress in critically ill patients and its potential pathophysiologic role, as well as the results of recent clinical trials of antioxidant therapies. RECENT FINDINGS:Several lines of evidence confirm th...

journal_title：Current opinion in critical care

authors： Lovat R,Preiser JC

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantable cardioverter-defibrillator (ICD) implantation is the standard of care for secondary prevention in patients with previous cardiac arrest and for primary prevention in appropriately selected patients with cardiomyopathy. However, ICD therapies and the arrhythmias that trigger these therapies...

journal_title：Current opinion in critical care

authors： Bradfield JS,Buch E,Shivkumar K

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Fried E,Weissman C,Sprung C

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Prerenal failure is used to designate a reversible form of acute renal dysfunction. However, the terminology encompasses several different conditions that vary considerably. The lack of a widely accepted definition for prerenal failure makes it impossible to determine the epidemiology, natural history...

journal_title：Current opinion in critical care

authors： Macedo E,Mehta RL

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current concepts in perioperative pulmonary management. RECENT FINDINGS:Preoperative risk assessment tools for perioperative pulmonary complications (POPCs) are evolving for both children and adults. Intraoperative management strategies have a demonstrable effect on outcomes. Lat...

journal_title：Current opinion in critical care

authors： Johnson DC,Kaplan LJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is commonplace in most ICUs. In many cases the cause is believed to be multifactorial with sepsis being a major component. However, occasionally intrinsic renal disease will present to the ICU and as such critical care practitioners should be aware of this possibility and the...

journal_title：Current opinion in critical care

authors： Amery CE,Forni LG

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the recent literature on the main aspects of perioperative acute kidney injury (AKI). RECENT FINDINGS:AKI occurs in 1 in every 10 surgical patients, with cardiac, orthopedic, and major abdominal surgeries being the procedures associated with the highest risk. Overall, comp...

journal_title：Current opinion in critical care

authors： Canet E,Bellomo R

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasin...

journal_title：Current opinion in critical care

authors： Festic E,Kor DJ,Gajic O

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Health-related quality of life (HRQoL) is an important patient-reported outcome measure following critical illness. 'Validated' and professionally endorsed generic measures are widely used to evaluate critical care intervention and guide practice, policy and research. Although recognizing that they ar...

journal_title：Current opinion in critical care

authors： Ramsay P

更新日期：2011-10-01 00:00:00

abstract：:Successes in machine-based extracorporeal support for different organ functions stimulated research in the field of liver support approximately 50 years ago. Initial failure to improve outcome using detoxification methods like dialysis, blood and plasma exchange, or plasmapheresis over sorbents fueled interest in biol...

journal_title：Current opinion in critical care

authors： Mitzner SR,Stange J,Peszynski P,Klammt S

更新日期：2002-04-01 00:00:00

abstract：:Widespread provision of early defibrillation following cardiac arrest holds major promise for improved survival from ventricular fibrillation. The critical element in predicting a successful outcome is the rapidity with which defibrillation is achieved. A worldwide awareness of this potential and its advocacy by such ...

journal_title：Current opinion in critical care

authors： White RD

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory di...

journal_title：Current opinion in critical care

authors： Rocco PR,Zin WA

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Uncertainty surrounding medical decision-making is particularly important during end-of-life decision-making. Doubts about the patient's best interests and prognostic accuracy may lead to conflict. RECENT FINDINGS:Many authors have suggested recently that medical attitudes to uncertainty need review....

journal_title：Current opinion in critical care

authors： Ridley S,Fisher M

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

journal_title：Current opinion in critical care

authors： Edwards D,Nirmalan M

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We discuss the goals of resuscitation, in both the early and the later phases, measures of organ perfusion, fluid responsiveness and the consequences of tissue edema. RECENT FINDINGS:The cost of over-aggressive fluid resuscitation is increased organ failure and mortality. In anticipation of the upcom...

journal_title：Current opinion in critical care

authors： Douglas JJ,Walley KR

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Increased use of advanced life-sustaining measures in patients with poor long-term expectations secondary to more chronic organ dysfunctions, comorbidities and/or a poor quality of life has become a worrying trend over the last decade. This can lead to futile, disproportionate or inappropriate care in...

journal_title：Current opinion in critical care

authors： Kompanje EJ,Piers RD,Benoit DD

更新日期：2013-12-01 00:00:00