Prompt antibiotic administration and goal-directed hemodynamic support in patients with severe sepsis and septic shock.

abstract：PURPOSE OF REVIEW:To describe and put into context recent conceptual advances regarding the relationship of energy load and power to ventilator-induced lung injury (VILI). RECENT FINDINGS:Investigative emphasis regarding VILI has almost exclusively centered on the static characteristics of the individual tidal cycle -...

journal_title：Current opinion in critical care

authors： Marini JJ

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. This review provides an overview of these new clinical data and also explores new areas of investigation for HFOV in ...

journal_title：Current opinion in critical care

authors： Ng J,Ferguson ND

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The scope of this review is to describe what is known about injury outcomes and the principles by which they can be improved by acute phase interventions. Assessing which outcomes matter to trauma patients is important both for the evaluation of existing and novel acute interventions and to assess the...

journal_title：Current opinion in critical care

authors： Brohi K,Cole E,Hoffman K

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Multimodal monitoring has emerged as a novel paradigm of care in acute brain injury, and in this context the value of noninvasive devices is increasingly under scrutiny. This narrative review summarizes recent clinical investigation focused on the role of automated infrared pupillometry (AIP) and opti...

journal_title：Current opinion in critical care

authors： Romagnosi F,Bongiovanni F,Oddo M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The comparison of morbidity, mortality, and length-of-stay outcomes in patients receiving critical care requires adjustment based on their presenting illness. These adjustments are made with severity-of-illness models. These models must be periodically updated to reflect current medical practices. Thi...

journal_title：Current opinion in critical care

authors： Higgins TL,Teres D,Nathanson B

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize new concepts regarding the occurrence, prevention, and management of medical complications following subarachnoid hemorrhage. RECENT FINDINGS:Data regarding the impact of common medical complications after subarachnoid hemorrhage on delayed cerebral ischemia and neurological outcome afte...

journal_title：Current opinion in critical care

authors： Wartenberg KE,Mayer SA

更新日期：2006-04-01 00:00:00

abstract：:Successes in machine-based extracorporeal support for different organ functions stimulated research in the field of liver support approximately 50 years ago. Initial failure to improve outcome using detoxification methods like dialysis, blood and plasma exchange, or plasmapheresis over sorbents fueled interest in biol...

journal_title：Current opinion in critical care

authors： Mitzner SR,Stange J,Peszynski P,Klammt S

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Successful treatment of cardiac arrest requires that an electrically stable and mechanically competent cardiac activity be promptly reestablished. However, many interventions used to attempt to reestablish cardiac activity may also inflict additional myocardial injury and, in turn, compromise resuscit...

journal_title：Current opinion in critical care

authors： Gazmuri RJ,Ayoub IM,Kolarova J

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the progress made over the past 20 years in the treatment of septic shock, mortality remains high. Microcirculatory disorders raise considerable interest aiming to improve the understanding of the physiopathology of septic shock and its management. RECENT FINDINGS:Numerous experimental and cl...

journal_title：Current opinion in critical care

authors： Ait-Oufella H,Bourcier S,Lehoux S,Guidet B

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival of critically ill patients is frequently associated with significant functional impairment and reduced health-related quality of life. Early rehabilitation of ICU patients has recently been identified as an important focus for interdisciplinary ICU teams. However, the amount of rehabilitation...

journal_title：Current opinion in critical care

authors： Gosselink R,Needham D,Hermans G

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent data about Acinetobacter baumannii pneumonia epidemiology and the therapeutic options including adjunctive nebulized therapy. RECENT FINDINGS:A. baumannii is a major cause of nosocomial pneumonia in certain geographic areas affecting mainly debilitated patients, with prolonged hosp...

journal_title：Current opinion in critical care

authors： Amaya-Villar R,Garnacho-Montero J

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:A significant number of patients hospitalized with heart failure are malnourished. Depletion of micronutrients, which is known to occur in heart failure for a variety of reasons, may contribute to myocardial abnormalities noted in heart failure. In this review, we focus on nutritional supplementation ...

journal_title：Current opinion in critical care

authors： Sarma S,Gheorghiade M

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Conventional intermittent hemodialysis and continuous veno-venous hemofiltration are the opposite poles of current treatment modalities for patients with acute renal failure in the intensive care unit. Because both intermittent and continuous renal replacement techniques have several disadvantages, al...

journal_title：Current opinion in critical care

authors： Fliser D,Kielstein JT

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update of recent developments pertaining to the use of percutaneous tracheostomy. Percutaneous tracheostomy has been established as an alternative to open surgical tracheostomy, but many key questions about the optimal use of this procedure remain unanswered...

journal_title：Current opinion in critical care

authors： Bardell T,Drover JW

更新日期：2005-08-01 00:00:00

abstract：:The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

journal_title：Current opinion in critical care

authors： Holcomb BW,Wheeler AP,Ely EW

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe acute respiratory syndrome (SARS) is a new disease that caused large outbreaks in several countries in the first half of 2003, resulting in infection in more than 8000 people and more than 900 deaths. During that time, a large body of literature rapidly emerged describing the clinical disease, ...

journal_title：Current opinion in critical care

authors： Lapinsky SE,Granton JT

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Although vitamin C is essentially a nontoxic vitamin; however, it is important to be aware regarding the safety of high doses before the wide clinical use. RECENT FINDINGS:Minor side effects of vitamin C have been reported, many being reported in earlier studies. High doses of vitamin C (up to 1.5 g/...

journal_title：Current opinion in critical care

authors： Khoshnam-Rad N,Khalili H

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Professional organizations, consensus groups, and stakeholders are calling for better palliative care in acute care settings, particularly in ICUs. Our ability to deliver that care is dependent on the outcomes associated with palliative care in the ICU. This review provides a conceptual framework for ...

journal_title：Current opinion in critical care

authors： Aslakson RA,Bridges JF

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the current intensive care management of acute liver failure (ALF) and the latest evidence for emerging therapies. RECENT FINDINGS:Mortality from ALF continues to improve and in some cases, medical therapy can negate the need for liver transplantation because of protocolized man...

journal_title：Current opinion in critical care

authors： Trovato FM,Rabinowich L,McPhail MJW

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review is to discuss new physiological and clinical insights in ventilator weaning tha...

journal_title：Current opinion in critical care

authors： Haaksma ME,Tuinman PR,Heunks L

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To review advances over the last year in the prevention, diagnosis and management of acute pancreatitis. RECENT FINDINGS:Obesity is an independent risk factor for severity in acute pancreatitis, and heavy alcohol consumption for the development of necrosis in severe acute pancreatitis. Biochemical ma...

journal_title：Current opinion in critical care

authors： Skipworth JR,Pereira SP

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Over the past decades, survival of critically ill hematological patients has dramatically improved, and these patients are more frequently referred to the ICU for intensive treatment, including a rising need for administering anticancer-therapy in this setting. RECENT FINDINGS:The scarce literature o...

journal_title：Current opinion in critical care

authors： Moors I,Pène F,Lengline É,Benoit D

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent and serious event associated with a high rate of complications, with an increased risk of progression to multiple organ dysfunction and excessive 'attributable' mortality. AKI affects all physiologic functions and organ systems with interrelated mechanisms, incl...

journal_title：Current opinion in critical care

authors： Druml W

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Glutamine (GLN) is a versatile amino acid, long believed to have important implications in ICU and surgical patients. An extensive body of data examining GLN supplementation of TPN demonstrated a consistent signal of improved outcomes. However, recently signals of risk have come from two large-scale m...

journal_title：Current opinion in critical care

authors： Wischmeyer PE

更新日期：2019-08-01 00:00:00

abstract：:Critical illness polyneuropathy (CIP) is a syndrome that was first extensively described in the early 1980s, mainly in patients with failure to wean from mechanical ventilation. The syndrome is further characterized by limb muscle weakness, usually more pronounced distally than proximally, and is often accompanied by ...

journal_title：Current opinion in critical care

authors： van Mook WN,Hulsewé-Evers RP

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

journal_title：Current opinion in critical care

authors： Flaatten H

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Although providing palliative care in the ICU has become a priority, the success of different methods to integrate palliative care into the ICU has varied. This review examines the current evidence supporting the different models of palliative care delivery and highlights areas for future study. RECE...

journal_title：Current opinion in critical care

authors： Hua M,Wunsch H

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy. RECENT...

journal_title：Current opinion in critical care

authors： Brohi K,Cohen MJ,Davenport RA

更新日期：2007-12-01 00:00:00

abstract：:Radiocontrast nephropathy may in part be mediated by generation of reactive oxygen species causing direct toxic damage to renal tubular epithelial cell and renal medullary ischemia. Data from experimental studies indicated that antioxidants, eg, acetylcysteine, may prevent radiocontrast-induced nephropathy. Recently, ...

journal_title：Current opinion in critical care

authors： Tepel M,Zidek W

更新日期：2001-12-01 00:00:00