Acetylcysteine for radiocontrast nephropathy.

Abstract:

:Radiocontrast nephropathy may in part be mediated by generation of reactive oxygen species causing direct toxic damage to renal tubular epithelial cell and renal medullary ischemia. Data from experimental studies indicated that antioxidants, eg, acetylcysteine, may prevent radiocontrast-induced nephropathy. Recently, one prospective, randomized, placebo-controlled study in patients with moderate renal insufficiency confirmed that the prophylactic oral administration of acetylcysteine at a dose of 600 mg twice daily along with hydration prevents the reduction in renal function by a nonionic, low-osmolality radiocontrast agent.

journal_name

Curr Opin Crit Care

authors

Tepel M,Zidek W

doi

10.1097/00075198-200112000-00004

keywords:

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

390-2

issue

6

eissn

1070-5295

issn

1531-7072

journal_volume

7

pub_type

杂志文章,评审
  • Insights in pediatric ventilation: timing of intubation, ventilatory strategies, and weaning.

    abstract:PURPOSE OF REVIEW:Mechanical ventilation is a common intervention provided by pediatric intensivists. This fact notwithstanding, the management of mechanical ventilation in pediatrics is largely guided by a few pediatric trials along with careful interpretation and application of adult data. RECENT FINDINGS:A low tida...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e32801297f9

    authors: Turner DA,Arnold JH

    更新日期:2007-02-01 00:00:00

  • Neuroprognostication after cardiac arrest in the light of targeted temperature management.

    abstract:PURPOSE OF REVIEW:Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guideline...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000406

    authors: Oddo M,Friberg H

    更新日期:2017-06-01 00:00:00

  • Renal dysfunction and fluid and electrolyte disturbances.

    abstract:PURPOSE OF REVIEW:To examine recent developments in preventing and treating postoperative acute renal dysfunction. To review contemporary issues concerning perioperative fluid and electrolyte management. RECENT FINDINGS:Renal dysfunction remains a major postoperative morbidity despite the advent of intermittent and co...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328348bef5

    authors: Hashem R,Weissman C

    更新日期:2011-08-01 00:00:00

  • Paralytics in critical care: not always the bad guy.

    abstract:PURPOSE OF REVIEW:The use of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS) and acute lung injury remains controversial, although frequent. This review analyzes the effects of NMBAs on thoracopulmonary mechanics, gas exchange, patient outcome and their potential advers...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/mcc.0b013e3283220e60

    authors: Forel JM,Roch A,Papazian L

    更新日期:2009-02-01 00:00:00

  • Cell-based therapies for the acute respiratory distress syndrome.

    abstract:PURPOSE OF REVIEW:Acute respiratory distress syndrome (ARDS) is a multifaceted lung disease with no current effective therapy. Many clinical trials using conventional pharmacologic therapies have failed, suggesting the need to examine alternative approaches. Thus, attention has focused on the therapeutic potential of c...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000061

    authors: Maron-Gutierrez T,Laffey JG,Pelosi P,Rocco PR

    更新日期:2014-02-01 00:00:00

  • How to assess liver function?

    abstract:PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3283361813

    authors: Kortgen A,Recknagel P,Bauer M

    更新日期:2010-04-01 00:00:00

  • Resuscitation beyond the abdominal compartment syndrome.

    abstract:PURPOSE OF REVIEW:In the 1980s, we witnessed tremendous advances in trauma care including trauma system development, advanced trauma life support, damage control surgery and ICU resuscitation. As a result, patients who used to bleed to death in the operating room survived. However, many went on to develop multiple orga...

    journal_title:Current opinion in critical care

    pub_type: 社论

    doi:10.1097/MCC.0b013e3283409d16

    authors: Gonzalez EA,Moore FA

    更新日期:2010-12-01 00:00:00

  • Diagnosis of nonventilated hospital-acquired pneumonia: how much do we know?

    abstract:PURPOSE OF REVIEW:To describe the current knowledge about clinical and microbiological diagnosis of nonventilated hospital-acquired pneumonia (NV-HAP). RECENT FINDINGS:NV-HAP is emerging as a new challenge for clinicians, particularly because VAP incidence has been decreasing. The clinical diagnosis of NV-HAP uses the...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000525

    authors: Ranzani OT,De Pascale G,Park M

    更新日期:2018-10-01 00:00:00

  • Clinical relevance of monitoring respiratory mechanics in the ventilator-supported patient: an update (1995-2000).

    abstract::The introduction of mechanical ventilation in the intensive care unit environment had the merit of putting a potent life-saving tool in the physicians' hands in a number of situations; however, like most sophisticated technologies, it can cause severe side effects and eventually increase mortality if improperly applie...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200102000-00007

    authors: Appendini L,Confalonieri M,Rossi A

    更新日期:2001-02-01 00:00:00

  • Update on the management of acute liver failure.

    abstract:PURPOSE OF REVIEW:This review describes the current intensive care management of acute liver failure (ALF) and the latest evidence for emerging therapies. RECENT FINDINGS:Mortality from ALF continues to improve and in some cases, medical therapy can negate the need for liver transplantation because of protocolized man...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000583

    authors: Trovato FM,Rabinowich L,McPhail MJW

    更新日期:2019-04-01 00:00:00

  • Prevention of acute respiratory distress syndrome.

    abstract:PURPOSE OF REVIEW:The paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasin...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000174

    authors: Festic E,Kor DJ,Gajic O

    更新日期:2015-02-01 00:00:00

  • Severe cardiac disease in pregnancy, part II: impact of congenital and acquired cardiac diseases during pregnancy.

    abstract:PURPOSE OF REVIEW:Part II of this review gives an overview of the different maternal cardiac problems during pregnancy and their management, and developments over recent years. RECENT FINDINGS:Many studies published over the last 5 years provided new insights on different cardiac diseases in pregnancy. Publications di...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ccx.0000179806.15328.b9

    authors: van Mook WN,Peeters L

    更新日期:2005-10-01 00:00:00

  • Advancements in the critical care management of status epilepticus.

    abstract:PURPOSE OF REVIEW:Status epilepticus has a high morbidity and mortality. There are little definitive data to guide management; however, new recent data continue to improve understanding of management options of status epilepticus. This review examines recent advancements regarding the critical care management of status...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000392

    authors: Bauerschmidt A,Martin A,Claassen J

    更新日期:2017-04-01 00:00:00

  • Extracorporeal gas exchange.

    abstract:PURPOSE OF REVIEW:We report on recent advances and achievements on the use of extracorporeal gas exchange for long-term application in the therapy of critically ill patients with various forms of respiratory failure. RECENT FINDINGS:The most important results regarding the use of extracorporeal gas exchange are expect...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e3283220e1f

    authors: Pesenti A,Zanella A,Patroniti N

    更新日期:2009-02-01 00:00:00

  • Resuscitative endovascular balloon occlusion of the aorta: promise, practice, and progress?

    abstract:PURPOSE OF REVIEW:Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000367

    authors: Perkins ZB,Lendrum RA,Brohi K

    更新日期:2016-12-01 00:00:00

  • Clinical trials in ventilator treatment: current perspectives and future challenges.

    abstract:PURPOSE OF REVIEW:Mortality/morbidity-based end points have been useful in evaluating treatments that modulate 'mediator variables' with a large effect size. Ventilation is usually a supportive measure, and hence is best seen as a 'moderator variable'. It can, therefore, have only a modest impact on disease-specific mo...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/mcc.0b013e32833548cf

    authors: Edwards D,Nirmalan M

    更新日期:2010-02-01 00:00:00

  • Renal disease presenting as acute kidney injury: the diagnostic conundrum on the intensive care unit.

    abstract:PURPOSE OF REVIEW:Acute kidney injury (AKI) is commonplace in most ICUs. In many cases the cause is believed to be multifactorial with sepsis being a major component. However, occasionally intrinsic renal disease will present to the ICU and as such critical care practitioners should be aware of this possibility and the...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000155

    authors: Amery CE,Forni LG

    更新日期:2014-12-01 00:00:00

  • Gut dysfunction in the ICU: diagnosis and management.

    abstract:PURPOSE OF REVIEW:Progress has been made in our understanding of gut dysfunction in critical illness. This review will outline new findings and give perspectives based on previous knowledge and concurrent advances in nutrition. RECENT FINDINGS:The relationship between gut dysfunction and poor outcomes in critical illn...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章

    doi:10.1097/MCC.0000000000000813

    authors: Chapple LS,Plummer MP,Chapman MJ

    更新日期:2021-01-21 00:00:00

  • Traumatic brain injury.

    abstract:PURPOSE OF REVIEW:Management of the patient with traumatic brain injury is a rapidly advancing field, characterized in recent years by an improved understanding of intracranial pathophysiology and ways in which outcomes can be improved. Many traditional therapies, such as fluid restriction and hyperventilation, have be...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200312000-00007

    authors: Dutton RP,McCunn M

    更新日期:2003-12-01 00:00:00

  • New ways to reduce unnecessary variation and improve outcomes in the intensive care unit.

    abstract::The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200108000-00015

    authors: Holcomb BW,Wheeler AP,Ely EW

    更新日期:2001-08-01 00:00:00

  • Effects of alcohol on the heart.

    abstract::Some evidence suggests that light to moderate alcohol consumption protects against cardiovascular diseases. However, this cardioprotective effect of alcohol consumption in adults is absent at the population level. Approximately 20 to 30% of patients admitted to a hospital are alcohol abusers. In medical practice, it i...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200110000-00004

    authors: Spies CD,Sander M,Stangl K,Fernandez-Sola J,Preedy VR,Rubin E,Andreasson S,Hanna EZ,Kox WJ

    更新日期:2001-10-01 00:00:00

  • Extracorporeal life support for severe acute respiratory distress syndrome.

    abstract:PURPOSE OF REVIEW:To provide a summary of the recent literature on extracorporeal membrane oxygenation (ECMO) in adults with severe acute respiratory distress syndrome (ARDS), focusing on advances in equipment, current conventional and unconventional indications, complications, and future applications. RECENT FINDINGS...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000170

    authors: Leligdowicz A,Fan E

    更新日期:2015-02-01 00:00:00

  • The timing of spinal stabilization in polytrauma and in patients with spinal cord injury.

    abstract:PURPOSE OF REVIEW:Despite improved care of multiple injured patients, controversial data about the best time point for decompression and stabilization of spine fractures and spinal cord injuries are published. Some studies even question the value of surgical management. RECENT FINDINGS:In several mostly retrospective ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328319650b

    authors: Schinkel C,Anastasiadis AP

    更新日期:2008-12-01 00:00:00

  • The science and art of pediatric critical care nutrition.

    abstract:PURPOSE OF REVIEW:Nutritional status and nutrient delivery during critical illness impact clinical outcomes. We have reviewed recent studies that may guide best practices regarding nutrition therapy in critically ill children. RECENT FINDINGS:Malnutrition is prevalent in the pediatric ICU population, and is associated...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000316

    authors: Martinez EE,Mehta NM

    更新日期:2016-08-01 00:00:00

  • Advances in burn care.

    abstract:PURPOSE OF REVIEW:This article reviews and critiques new developments in the critical care of burn patients. RECENT FINDINGS:The practice of restrictive transfusion is slowly gaining traction. Abdominal compartment syndrome is associated with resuscitation volumes of 300 ml/kg per 24 h, and percutaneous decompression ...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328263888f

    authors: Namias N

    更新日期:2007-08-01 00:00:00

  • Disaster preparation and management for the intensive care unit.

    abstract::The purpose of this report is to provide information regarding preparation for disaster management from the perspective of ICU physicians. Both a framework toward ICU preparation for disaster management and a guide to the relevant literature are presented. Our objective is to show that the understanding of disaster pr...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200212000-00021

    authors: Roccaforte JD,Cushman JG

    更新日期:2002-12-01 00:00:00

  • Optimal use of existing and new antifungal drugs.

    abstract::Clinicians are increasingly aware that fungal pathogens are a significant cause of morbidity and mortality in hospitalized patients. Historically, these infections occurred in severely immunocompromised patients who were undergoing treatment for hematological malignancy or solid organ transplantation. Currently, howev...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/00075198-200108000-00005

    authors: Rogers TR

    更新日期:2001-08-01 00:00:00

  • Trauma rehabilitation outcome scoring.

    abstract:PURPOSE OF REVIEW:Appropriate measurements of success in trauma systems are evolving. We review the rationale behind prior trauma and rehabilitation outcomes measures, and how they have led to the current rehabilitation tools in use today. In addition, we review the difficulties with current methods and future improvem...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0b013e328307f25f

    authors: Horwitz DA,Schuerer DJ

    更新日期:2008-08-01 00:00:00

  • Dissipation of energy during the respiratory cycle: conditional importance of ergotrauma to structural lung damage.

    abstract:PURPOSE OF REVIEW:To describe and put into context recent conceptual advances regarding the relationship of energy load and power to ventilator-induced lung injury (VILI). RECENT FINDINGS:Investigative emphasis regarding VILI has almost exclusively centered on the static characteristics of the individual tidal cycle -...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000470

    authors: Marini JJ

    更新日期:2018-02-01 00:00:00

  • Antimicrobial resistance in ICUs: an update in the light of the COVID-19 pandemic.

    abstract:PURPOSE OF REVIEW:To describe current antimicrobial resistance in ESKAPE Gram-negative microorganisms and their situation in the ICUs, the implication of the so-called high-risk clones (HiRCs) involved in the spread of antimicrobial resistance as well as relevance of the COVID-19 pandemic in the potential increase of r...

    journal_title:Current opinion in critical care

    pub_type: 杂志文章,评审

    doi:10.1097/MCC.0000000000000755

    authors: Cantón R,Gijón D,Ruiz-Garbajosa P

    更新日期:2020-10-01 00:00:00