Microcirculatory disorders in sepsis and transplantation: therapy with natural coagulatory inhibitors antithrombin and activated protein C.

abstract：PURPOSE OF REVIEW:Acute kidney injury (AKI) is a frequent finding in critically ill patients and is associated with adverse outcomes. With the purpose of improving outcome of AKI, the Kidney Disease: Improving Global Outcomes (KDIGO) group, a group of experts in critical care nephrology, has presented a set of guidelin...

journal_title：Current opinion in critical care

authors： Hoste EA,De Corte W

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore the origin of myths and their progression toward dogma. The process of debunking myths in the neurocritical care unit (NCCU) is facilitated if nurses are involved early during the process. RECENT FINDINGS:Current and past practices in the NCCU were reviewed through our personal experiences...

journal_title：Current opinion in critical care

authors： Olson DM,Figueroa SA

更新日期：2014-04-01 00:00:00

abstract：:Nosocomial pneumonia is a dynamic disease with multiple etiologic agents and a changing natural history. The highest attack rates and mortality occur in patients with ventilator-associated pneumonia. Diagnosis of nosocomial pneumonia is often made by clinical criteria that are sensitive but lack specificity. The use o...

journal_title：Current opinion in critical care

authors： Craven DE,De Rosa FG,Thornton D

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of microcirculatory abnormalities in critically ill patients and the link between systemic hemodynamics and microvascular perfusion. RECENT FINDINGS:Microcirculatory alterations have been repeatedly observed in patients with severe sepsis, but recent findings show that these also ...

journal_title：Current opinion in critical care

authors： De Backer D,Ortiz JA,Salgado D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications...

journal_title：Current opinion in critical care

authors： Perkins ZB,Lendrum RA,Brohi K

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We sought to review the evidence supporting neurocritical care as a distinct specialty of medicine. RECENT FINDINGS:Over the past 20 years, neuro-intensive care units have evolved from neurosurgical units focused primarily on postoperative monitoring to units that provide comprehensive medical and sp...

journal_title：Current opinion in critical care

authors： Rincon F,Mayer SA

更新日期：2007-04-01 00:00:00

abstract：:Reactive oxygen species are reactive, partially reduced derivatives of molecular oxygen (O 2 ). Important reactive oxygen species in biologic systems include superoxide radical anion, hydrogen peroxide, and hydroxyl radical. Closely related species include the hypohalous acids, particularly hypochlorous acid; chlorami...

journal_title：Current opinion in critical care

authors： Fink MP

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantable cardioverter-defibrillator (ICD) implantation is the standard of care for secondary prevention in patients with previous cardiac arrest and for primary prevention in appropriately selected patients with cardiomyopathy. However, ICD therapies and the arrhythmias that trigger these therapies...

journal_title：Current opinion in critical care

authors： Bradfield JS,Buch E,Shivkumar K

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Progress has been made in our understanding of gut dysfunction in critical illness. This review will outline new findings and give perspectives based on previous knowledge and concurrent advances in nutrition. RECENT FINDINGS:The relationship between gut dysfunction and poor outcomes in critical illn...

journal_title：Current opinion in critical care

authors： Chapple LS,Plummer MP,Chapman MJ

更新日期：2021-01-21 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the clear rationale for evidence-based medicine (EvBM) in the challenging realms of resuscitation research, yet also provide case examples in which even the well designed, multicentered randomized clinical trial may have had unrecognized limitations, and thus misleading results. This is whe...

journal_title：Current opinion in critical care

authors： Pepe PE,Aufderheide TP

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The risk of adverse outcome in patients undergoing major surgery is affected both by cardiorespiratory fitness, and the presence and severity of comorbidities. Accurate risk stratification is essential for the identification of patients who may benefit from specific perioperative management strategies...

journal_title：Current opinion in critical care

authors： Moonesinghe SR,Mythen MG,Grocott MP

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Tissue hypoperfusion is a common pathophysiologic process leading to multiple-organ dysfunction and death. An important goal of hemodynamic monitoring is the early detection of inadequate tissue perfusion and oxygenation. The use of simple, noninvasive monitoring techniques has the advantage of facili...

journal_title：Current opinion in critical care

authors： Creteur J

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review advances over the last year in the prevention, diagnosis and management of acute pancreatitis. RECENT FINDINGS:Obesity is an independent risk factor for severity in acute pancreatitis, and heavy alcohol consumption for the development of necrosis in severe acute pancreatitis. Biochemical ma...

journal_title：Current opinion in critical care

authors： Skipworth JR,Pereira SP

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Selenium is a trace element essential to human health. Critical illness is associated with the generation of oxygen free radicals resulting in a condition of oxidative stress. Supplementing critically ill patients with antioxidant nutrients may improve survival. Selenium levels can be low due to redis...

journal_title：Current opinion in critical care

authors： Geoghegan M,McAuley D,Eaton S,Powell-Tuck J

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Care surrounding end-of-life has become a major topic in the intensive care medicine literature. Cultural and regional variations are associated with transatlantic debates about decisions to forego life-sustaining therapies and lead to recent international statements. The aim of this review is to prov...

journal_title：Current opinion in critical care

authors： Fassier T,Lautrette A,Ciroldi M,Azoulay E

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and examine the efficacy of recently described medical and surgical interventions after acute ischaemic stroke using data from well conducted, clinical trials and systematic reviews. This review will consider recently published or updated articles. RECENT FINDINGS:As therapeutic options evo...

journal_title：Current opinion in critical care

authors： Andrews PJ

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Fever is common in the ICU among patients with severe brain injury. Fever has been consistently shown to exacerbate brain injuries in animal models and has been consistently associated with poor outcome in human studies. However, whether fever control improves outcome and the ideal means of fever cont...

journal_title：Current opinion in critical care

authors： Bohman LE,Levine JM

更新日期：2014-04-01 00:00:00

abstract：:Radiocontrast nephropathy may in part be mediated by generation of reactive oxygen species causing direct toxic damage to renal tubular epithelial cell and renal medullary ischemia. Data from experimental studies indicated that antioxidants, eg, acetylcysteine, may prevent radiocontrast-induced nephropathy. Recently, ...

journal_title：Current opinion in critical care

authors： Tepel M,Zidek W

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although conventional anticonvulsant agents can terminate status epilepticus in most cases, a substantial minority of patients develops medically refractory status and requires more aggressive care. This review explores the options available. RECENT FINDINGS:Increasing numbers of previously unexpecte...

journal_title：Current opinion in critical care

authors： Bleck TP

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of re...

journal_title：Current opinion in critical care

authors： Pineton de Chambrun M,Bréchot N,Combes A

更新日期：2018-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As incidence of acute lung injury (ALI) increases and case fatality decreases, long-term care of survivors is of public health importance. Previous studies demonstrate that these survivors are at risk for impairment in physical, cognitive and mental health. In this review, we will discuss recent studi...

journal_title：Current opinion in critical care

authors： Hough CL,Herridge MS

更新日期：2012-02-01 00:00:00

abstract：:The care of critically ill patients and the advent of the modern day intensive care unit (ICU) present a large person power and cost burden to society. The high cost of critical care is attributed to high overhead expenses (eg, experienced staff and equipment), high resource utilization (eg, pharmaceutical resources, ...

journal_title：Current opinion in critical care

authors： Holcomb BW,Wheeler AP,Ely EW

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although vitamin C is essentially a nontoxic vitamin; however, it is important to be aware regarding the safety of high doses before the wide clinical use. RECENT FINDINGS:Minor side effects of vitamin C have been reported, many being reported in earlier studies. High doses of vitamin C (up to 1.5 g/...

journal_title：Current opinion in critical care

authors： Khoshnam-Rad N,Khalili H

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will discuss the rationale and clinical utility of percutaneous left ventricular assist devices in the management of patients with cardiogenic shock. RECENT FINDINGS:Left ventricular assist devices maintain partial or total circulatory support in case of severe left ventricular failure. C...

journal_title：Current opinion in critical care

authors： Windecker S

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Status epilepticus has a high morbidity and mortality. There are little definitive data to guide management; however, new recent data continue to improve understanding of management options of status epilepticus. This review examines recent advancements regarding the critical care management of status...

journal_title：Current opinion in critical care

authors： Bauerschmidt A,Martin A,Claassen J

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of the invasive monitoring techniques pulmonary artery catheter (PAC) and transpulmonary thermodilution (TPD) for cardiopulmonary monitoring in the critically ill patient. RECENT FINDINGS:Characterization of the nature of hemodynamic alterations and hemodynamic optimization can be...

journal_title：Current opinion in critical care

authors： De Backer D,Fagnoul D,Herpain A

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Multimodal monitoring has emerged as a novel paradigm of care in acute brain injury, and in this context the value of noninvasive devices is increasingly under scrutiny. This narrative review summarizes recent clinical investigation focused on the role of automated infrared pupillometry (AIP) and opti...

journal_title：Current opinion in critical care

authors： Romagnosi F,Bongiovanni F,Oddo M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Stress ulcer prophylaxis (SUP) is considered standard of care in the majority of critically ill patients in the ICU. In this review, we will present the current evidence for the use of SUP in ICU patients, including data on the prevalence of gastrointestinal bleeding and the balance between benefits a...

journal_title：Current opinion in critical care

authors： Krag M,Perner A,Møller MH

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the improvements in its management, community-acquired pneumonia (CAP) still exhibits high global morbidity and mortality rates, especially in elderly patients. This review focuses on the most recent findings on the epidemiology, cause, diagnosis and management of CAP. RECENT FINDINGS:There i...

journal_title：Current opinion in critical care

authors： Cillóniz C,Dominedò C,Garcia-Vidal C,Torres A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the review is to summarize and discuss recent research regarding the role of mechanical ventilation in producing weakness and atrophy of the diaphragm in critically ill patients, an entity termed ventilator-induced diaphragmatic dysfunction (VIDD). RECENT FINDINGS:Severe weakness of th...

journal_title：Current opinion in critical care

authors： Petrof BJ,Hussain SN

更新日期：2016-02-01 00:00:00