Abstract:
:In the midst of the post-war turmoil in Japan, I fortunately followed a path to become a scientist. Sometime at an early stage of my career, I encountered the problem of the cellular response to DNA damage and had the chance to discover a DNA repair enzyme. This event greatly influenced the subsequent course of my research, and I extended my studies toward elucidating the molecular mechanisms of mutagenesis as well as of carcinogenesis. Through these studies I came to understand the importance of mechanisms for dealing with the actions of reactive oxygen species to the living systems. These recollections deal with these endeavors with emphasis on the early part of my scientific career.
journal_name
DNA Repair (Amst)journal_title
DNA repairauthors
Sekiguchi Mdoi
10.1016/j.dnarep.2006.03.002subject
Has Abstractpub_date
2006-06-10 00:00:00pages
750-8issue
6eissn
1568-7864issn
1568-7856pii
S1568-7864(06)00065-6journal_volume
5pub_type
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