Subcutaneous tissue fibroblast cytoskeletal remodeling induced by acupuncture: evidence for a mechanotransduction-based mechanism.

abstract：:The mobility of a cell surface protein on cells osmotically swollen by treatment with several different cell permeabilizing agents retains specific restraints despite detachment of the plasma membrane from the cortical cytoskeleton. Fluorescence photobleaching recovery experiments indicate that the lateral diffusion c...

journal_title：Journal of cellular physiology

authors： Feder TJ,Chang EY,Holowka D,Webb WW

更新日期：1994-01-01 00:00:00

abstract：:The Toll and Toll-like receptor signaling pathways are evolutionarily conserved pathways that regulate innate immunity in insects and mammals. While efforts have been made to clarify the signal transduction events that occur during infection, much less is known about the components that maintain immune quiescence. Her...

journal_title：Journal of cellular physiology

authors： Zhou B,Yun EY,Ray L,You J,Ip YT,Lin X

更新日期：2014-04-01 00:00:00

abstract：:Multiple studies have reported different methods in treating gestational diabetes mellitus (GDM); however, the relationship between miR-335-5p and GDM still remains unclear. Here, this study explores the effect of miR-335-5p on insulin resistance and pancreatic islet β-cell secretion via activation of the TGFβ signali...

journal_title：Journal of cellular physiology

authors： Tang XW,Qin QX

更新日期：2019-05-01 00:00:00

abstract：:Although the type 1 insulin-like growth factor receptor (IGF-IR) is a potent inhibitor of apoptosis, its C-terminus sequence sends contradictory signals, including a clearly proapoptotic signal. We have synthesized a peptide, peptide 2, having the sequence of the IGF-IR from residue 1282 to residue 1298 (C-terminus of...

journal_title：Journal of cellular physiology

authors： Reiss K,Yumet G,Shan S,Huang Z,Alnemri E,Srinivasula SM,Wang JY,Morrione A,Baserga R

更新日期：1999-10-01 00:00:00

abstract：:The human chronic myeloid leukemia cell line K562 acquires several megakaryoblastoid features when cultured in the presence of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA). We observed strongly increased secretion of several proteins into the culture media of K562 cells within a few hours of TPA trea...

journal_title：Journal of cellular physiology

authors： Alitalo R,Andersson LC,Tapiovaara H,Sistonen L,Vaheri A,Stephens R

更新日期：1989-07-01 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) is characterized by the formation of neurofibromas, benign tumors of the peripheral nerve consisting essentially of Schwann cells, which can sometimes turn malignant to form neurofibrosarcomas. The mechanism of progression toward a malignant phenotype remains largely unknown. In this rep...

journal_title：Journal of cellular physiology

authors： Badache A,De Vries GH

更新日期：1998-11-01 00:00:00

abstract：:Nowadays, epigenetics covers a crucial role in different fields of science. The enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2), is a big proponent of how epigenetic changes can affect the initiation and progression of several diseases. Through its catalytic activi...

journal_title：Journal of cellular physiology

authors： Sanna L,Marchesi I,Melone MAB,Bagella L

更新日期：2018-09-01 00:00:00

abstract：:Ehrlich ascites tumor cells from the plateau phase of growth were transplanted into new hosts, pulse-labeled with tritiated thymidine and blocked with repeated injections of vinblastine. When unlabeled cells were analyzed for their cellular DNA content utilizing a cytophotometric technique it was found that in relatio...

journal_title：Journal of cellular physiology

authors： Andersson G

更新日期：1977-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether mature human articular chondrocytes (AC) exhibit an antiproliferative effect on activated peripheral blood mononuclear cells (PBMC) and to compare this effect with other cells of mesenchymal origin. METHODS:AC from healthy cadaveric cartilage were grown for different passages, in the a...

journal_title：Journal of cellular physiology

authors： Bocelli-Tyndall C,Barbero A,Candrian C,Ceredig R,Tyndall A,Martin I

更新日期：2006-12-01 00:00:00

abstract：:HeLa (substrain Ho) grown in serum free medium showed an increase in the specific activity of alkaline phosphatase when fetal calf serum (10%) was added to the medium (9.7 nmoles/sec/mg protein to 86.8). Under the same conditions, eight intracellular enzymes showed no increase in activity. Similar results were obtaine...

journal_title：Journal of cellular physiology

authors： Carlson CW

更新日期：1979-01-01 00:00:00

abstract：:Trypsinized normal rat embryo fibroblasts and untrypsinized and trypsinized transformed rat fibroblasts have two orders of binding sites for bacterial glycolipid mR595. The high order sites fix 1--3 micrograms glycolipid mR595/10(5) cells and those of the low order fix about 6 microgram glycolipids mR595/10(6) cells. ...

journal_title：Journal of cellular physiology

authors： Lallier R,Trudel M,Brailovsky CA,Nigam VN

更新日期：1979-01-01 00:00:00

abstract：:Aberrations of DNA methylation are early events in the development of tumors. In this study, we investigated the DNA methylation status of growth hormone secretagogue receptor (GHSR), a promising pan-cancer biomarker, in gastric cancer (GC). Initially, data sets from DNA methylation and gene expression studies availab...

journal_title：Journal of cellular physiology

authors： Amini M,Foroughi K,Talebi F,Aghagolzade Haji H,Kamali F,Jandaghi P,Hoheisel JD,Manoochehri M

更新日期：2019-01-24 00:00:00

abstract：:Cell fusion occurs during fertilization and in the formation of organs such as muscles, placenta, and bones. We have developed an experimental model for epithelial cell fusion which permits analysis of the processes during junction disintegration and formation of polykaryons (Palovuori and Eskelinen [2000] Eur. J. Cel...

journal_title：Journal of cellular physiology

authors： Palovuori R,Myrsky E,Eskelinen S

更新日期：2004-09-01 00:00:00

abstract：:Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2. Muc4/SMC can act as an intramembrane ligand for ErbB2 via an EGF-like ...

journal_title：Journal of cellular physiology

authors： Price-Schiavi SA,Andrechek E,Idris N,Li P,Rong M,Zhang J,Carothers Carraway CA,Muller WJ,Carraway KL

更新日期：2005-04-01 00:00:00

abstract：:The development of acute pancreatitis (AP) is triggered by acinar events, but the subsequent extra-acinar events, particularly a distinct immune response, appear to determine its severity. Cytokines modulate this immune response and are derived not only from immunocytes but also from pancreatic acinar cells. We studie...

journal_title：Journal of cellular physiology

authors： Gallmeier E,Schäfer C,Moubarak P,Tietz A,Plössl I,Huss R,Göke B,Wagner AC

更新日期：2005-04-01 00:00:00

abstract：:Osteosarcoma is the most common malignant primary bone tumor in children and adolescents. The clinical outcome for osteosarcoma remains discouraging despite aggressive surgery and intensive radiotherapy and chemotherapy regimens. Thus, novel therapeutic approaches are needed. Previously, we have shown that inorganic p...

journal_title：Journal of cellular physiology

authors： Spina A,Sorvillo L,Di Maiolo F,Esposito A,D'Auria R,Di Gesto D,Chiosi E,Naviglio S

更新日期：2013-01-01 00:00:00

abstract：:The platelet-derived growth factor (PDGF) binds via a defined amino acid sequence to heparin (Fager et al., 1992, In Vitro Cell. Dev. Biol., 28A:176-180) and the protein moiety of low density lipoproteins (LDL; apo B-100) via a similar sequence to chondroitin sulfate (Camejo et al., 1988, Arteriosclerosis Thromb., 8:3...

journal_title：Journal of cellular physiology

authors： Fager G,Camejo G,Olsson U,Ostergren-Lundén G,Lustig F,Bondjers G

更新日期：1995-05-01 00:00:00

abstract：:In this review, we focused our attention on the more important natural extracellular matrix (ECM) molecules (collagen and fibrin), employed as cellular scaffolds for tissue engineering and on a class of semi-synthetic materials made from the fusion of specific oligopeptide sequences, showing biological activities, wit...

journal_title：Journal of cellular physiology

authors： Rosso F,Marino G,Giordano A,Barbarisi M,Parmeggiani D,Barbarisi A

更新日期：2005-06-01 00:00:00

abstract：:Acidic fibroblast growth factor (aFGF) mRNA was detected in a rat mammary fibroblastic cell line, but not in rat mammary epithelial cell lines or myoepithelial-like cell lines. Basic FGF (bFGF) mRNA was detected in both the fibroblasts and the myoepithelial-like cells, but was absent from the epithelial cells. A serie...

journal_title：Journal of cellular physiology

authors： Barraclough R,Fernig DG,Rudland PS,Smith JA

更新日期：1990-08-01 00:00:00

abstract：:Calcium ions (Ca2+ ) is the main element of dental pulp capping materials. Ca 2+ signaling plays a crucial role in a myriad of cell activities. An overwhelming array of studies have already reported the experimental and clinical benefits of Ca2+ -enriched materials in the treatment of teeth with accidental vital pulp ...

journal_title：Journal of cellular physiology

authors： An S

更新日期：2019-03-01 00:00:00

abstract：:KCNQ1 encodes a potassium voltage-gated channel and represents a susceptibility locus for type 2 diabetes mellitus (T2DM). Here, we explored the association between KCNQ1 polymorphisms and hypertension risk in individuals with T2DM, as well as the role of KCNQ1 in vascular smooth muscle cell contraction in vitro. To i...

journal_title：Journal of cellular physiology

authors： Huang KC,Li TM,Liu X,Chen JH,Chien WK,Shiao YT,Tsang H,Lin TH,Liao CC,Huang SM,Li JP,Lin CW,Lin JC,Lin CC,Lai CH,Cheng CF,Liang WM,Hung CH,Chen CC,Lin YJ,Tsai FJ

更新日期：2017-12-01 00:00:00

abstract：:The cellular proto-oncogene c-myc is an important transcription factor that plays a role in several cellular activities such as proliferation, differentiation, and apoptosis. It follows that regulation of c-myc expression is crucial for maintaining cell integrity. Amplification or translocation can convert this proto-...

journal_title：Journal of cellular physiology

authors： Habel ME,Lemieux R,Jung D

更新日期：2005-04-01 00:00:00

abstract：:Several agents that act through G-protein-coupled receptors and also stimulate phosphoinositide-specific phospholipase C (PI-PLC), including angiotensin II, vasopressin, norepinephrine, and prostaglandin (PG) F2alpha, activated the ERK1 (p44mapk) and ERK2 (p42mapk) members of the mitogen-activated protein (MAP) kinase...

journal_title：Journal of cellular physiology

authors： Melien O,Thoresen GH,Sandnes D,Ostby E,Christoffersen T

更新日期：1998-06-01 00:00:00

abstract：:Induction of vascular smooth muscle (VSM) alpha-actin mRNA expression during cytodifferentiation of mouse BC3H1 myogenic cells coincides with the accumulation of cell surface- and extracellular matrix-associated sulfated proteoglycans. Inhibition of proteoglycan biosynthesis in myogenic cells using an artificial beta-...

journal_title：Journal of cellular physiology

authors： Lee SH,Yan H,Reeser JC,Dillman JM,Strauch AR

更新日期：1995-07-01 00:00:00

abstract：:The present study extends our previous observation (Kasambalides and Lanks, J. Cell. Physiol., 114:93-98, 1983), that dexamethasone inhibits the alterations in heat shock protein (HSP) and glucose-regulated protein (GRP) synthesis caused by glucose deprivation. We now show that insulin, even in the presence of high ex...

journal_title：Journal of cellular physiology

authors： Kasambalides EJ,Lanks KW

更新日期：1985-05-01 00:00:00

abstract：:Circular RNAs (circRNAs) play critical roles in signal transduction during cell proliferation, differentiation, and apoptosis in a posttranscriptional manner. Recently, circRNAs have been proved to be a large class of animal RNAs with regulatory potency. However, whether circRNAs can respond to mechanical force (MF) a...

journal_title：Journal of cellular physiology

authors： Wang H,Feng C,Jin Y,Tan W,Wei F

更新日期：2019-07-01 00:00:00

abstract：:The clinical literature strongly suggests that bone healing in cigarette smokers is impaired. Since cigarette smoke (CS) contains numerous polycyclic aromatic hydrocarbons (PAHs), and since dioxins impair bone formation in vivo via the Aryl Hydrocarbon Receptor (AHR), we investigated the impact of PAH/AHR signaling on...

journal_title：Journal of cellular physiology

authors： Kung MH,Yukata K,O'Keefe RJ,Zuscik MJ

更新日期：2012-03-01 00:00:00

abstract：:The actin- and myosin-binding protein, caldesmon (CaD) is an essential component of the cytoskeleton in smooth muscle and non-muscle cells and is involved in the regulation of cell contractility, division, and assembly of actin filaments. CaD is abundantly present in endothelial cells (EC); however, the contribution o...

journal_title：Journal of cellular physiology

authors： Mirzapoiazova T,Kolosova IA,Romer L,Garcia JG,Verin AD

更新日期：2005-06-01 00:00:00

abstract：:Ubiquitin-specific protease 14 (USP14) is a ubiquitin-specific protease that is associated with the proteasome and plays important roles in cellular functions, viral infection, inflammatory responses, neurodegenerative diseases, and tumorigenesis. USP14 appears to have a dual function in regulating intracellular prote...

journal_title：Journal of cellular physiology

authors： Wang D,Ma H,Zhao Y,Zhao J

更新日期：2020-11-01 00:00:00

abstract：:NIH-3T3 cells transformed by the EJ-ras oncogene display reduced platelet-derived growth factor (PDGF)-stimulated phospholipase C activity as measured by inositol 1,4,5-triphosphate (IP3) synthesis and Ca2+ mobilization. The lack of PDGF-stimulated Ca2+ mobilization in EJ-ras transformed cells is not due to a loss of ...

journal_title：Journal of cellular physiology

authors： Olinger PL,Benjamin CW,Gorman RR,Connor JA

更新日期：1989-05-01 00:00:00