Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes.

abstract：:Stem cells are a unique class of cells that are capable of self-renewal and differentiation into multiple lineages. An increasing number of studies have suggested that both embryonic and adult stem cells possess primary cilia, antenna-like structures protruding from cell surfaces that are critical for sensing and tran...

journal_title：Journal of cellular physiology

authors： Lyu R,Zhou J

更新日期：2017-05-01 00:00:00

abstract：:Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with endothelial gap ju...

journal_title：Journal of cellular physiology

authors： Zhang YW,Morita I,Nishida M,Murota SI

更新日期：1999-09-01 00:00:00

abstract：:The cellular proto-oncogene c-myc is an important transcription factor that plays a role in several cellular activities such as proliferation, differentiation, and apoptosis. It follows that regulation of c-myc expression is crucial for maintaining cell integrity. Amplification or translocation can convert this proto-...

journal_title：Journal of cellular physiology

authors： Habel ME,Lemieux R,Jung D

更新日期：2005-04-01 00:00:00

abstract：:A serum factor which enhances the growth/viability of SV40 transformed 3T3 mouse fibroblasts, but not untransformed 3T3 cells in tissue culture has been partially purified from calf serum. The purification, which involves acidification to pH 2, chromatography on Sephadex G-100 at pH 2 followed by either Sephadex G-25 ...

journal_title：Journal of cellular physiology

authors： Young DV,Nakano ET,Wiggins DS,McElaney MA

更新日期：1978-08-01 00:00:00

abstract：:Theranostic nanoparticles (NPs) are promising for opening new windows toward personalized disease management. Using a single particle capable of both diagnosis and drug delivery, is the major benefit of such particles. In the present study, chitosan NPs were used as a dual action carrier for doxorubicin (DOX; chemothe...

journal_title：Journal of cellular physiology

authors： Gholami L,Tafaghodi M,Abbasi B,Daroudi M,Kazemi Oskuee R

更新日期：2019-02-01 00:00:00

abstract：:MCOLN1 encodes mucolipin-1 (TRPML1), a member of the transient receptor potential TRPML subfamily of channel proteins. Mutations in MCOLN1 cause mucolipidosis-type IV (MLIV), a lysosomal storage disorder characterized by severe neurologic, ophthalmologic, and gastrointestinal abnormalities. Along with TRPML1, there ar...

journal_title：Journal of cellular physiology

authors： Curcio-Morelli C,Zhang P,Venugopal B,Charles FA,Browning MF,Cantiello HF,Slaugenhaupt SA

更新日期：2010-02-01 00:00:00

abstract：:These are the reflections of a retired physician who was introduced to cellular physiology in 1947 at the University of Pennsylvania. I majored in Zoology. I took the required major courses, which were interesting but not exciting. I was a premedical student at the time. Fortunately I was introduced to cellular physio...

journal_title：Journal of cellular physiology

authors： Perelman A

更新日期：2015-11-01 00:00:00

abstract：:Cdk9/Cyclin T1 complex is very important in controlling specific differentiative pathways of several cell types. Limited data are available regarding the expression of Cdk9/Cyclin T1 in hematopoietic and lymphoid tissues. Cdk9/Cyclin T1 expression seems to be related to particular stages of lymphoid differentiation/ac...

journal_title：Journal of cellular physiology

authors： De Falco G,Leucci E,Onnis A,Bellan C,Tigli C,Wirths S,Cerino G,Cocco M,Crupi D,De Luca A,Lanzavecchia A,Tosi P,Leoncini L,Giordano A

更新日期：2008-04-01 00:00:00

abstract：:Male breast cancer (MBC) is an uncommon malignancy. We have previously reported that the expression of the Hippo transducers TAZ/YAP and their target CTGF was associated with inferior survival in MBC patients. Preclinical evidence demonstrated that Axl is a transcriptional target of TAZ/YAP. Thus, we herein assessed A...

journal_title：Journal of cellular physiology

authors： Di Benedetto A,Mottolese M,Sperati F,Ercolani C,Di Lauro L,Pizzuti L,Vici P,Terrenato I,Shaaban AM,Humphries MP,Sundara-Rajan S,Barba M,Speirs V,De Maria R,Maugeri-Saccà M

更新日期：2017-08-01 00:00:00

abstract：:Pleiotropic human KB cell mutants, selected for resistance to a conjugate of epidermal growth factor with Pseudomonas exotoxin (PE-EGF), were characterized genetically. These mutants have a pleiotropic phenotype, which includes reduced number of EGF receptors and reduced growth rate. Hybrid cells between HeLa D98 and ...

journal_title：Journal of cellular physiology

authors： Amano F,Pastan I,Gottesman MM

更新日期：1988-06-01 00:00:00

abstract：:Scientists of numerous medical and life science disciplines met in Siena, Italy to discuss the latest proceedings in basic and clinical research. General models of interconnected linear and back-feeding cell-cycle control pathways provide a basis for applied molecular research. Cell-cycle determining factors essential...

journal_title：Journal of cellular physiology

authors： Stiegler P,Giordano A

更新日期：2000-12-01 00:00:00

abstract：:Although it is well established that epidermal growth factor receptors (EGFRs) are asymmetrically expressed at the basolateral plasma membrane in polarized epithelial cells, how this process is regulated is not known. The purpose of this study was to address the mechanism of directed EGFR basolateral sorting using the...

journal_title：Journal of cellular physiology

authors： Hobert M,Carlin C

更新日期：1995-03-01 00:00:00

abstract：:Human lymphocytes were equilibrated for 48 hours at 5-6 mM K+ ex over a range of temperatures between 0 and 37 degrees C, and at 5 degrees C over a range of external K+ levels between 0 and 32 mM. Cell K+ and Na+ contents are normal between 37 and 10 decrees. Below 10 degrees there is a critical thermal transition in ...

journal_title：Journal of cellular physiology

authors： Negendank W,Shaller C

更新日期：1980-04-01 00:00:00

abstract：:Apoptosis of matrix producing cells is common among many inflammatory diseases. The goal of the present study was to examine the apoptotic effects of tumor necrosis factor-alpha (TNF-alpha) on fibroblastic cells in vivo and to investigate the role of different caspases in this process. This was accomplished in vivo by...

journal_title：Journal of cellular physiology

authors： Alikhani M,Alikhani Z,Raptis M,Graves DT

更新日期：2004-12-01 00:00:00

abstract：:O-linked N-acetylglucosamine (O-GlcNAc) protein modification has been implicated in the regulation of signaling pathways, cell function, and gene expression. Glutamine:fructose-6-phosphate amidotransferase-1 (GFAT-1) is the rate-limiting enzyme in the hexosamine biosynthetic pathway (HBP), which generates the sugar nu...

journal_title：Journal of cellular physiology

authors： Hsieh TJ,Lin T,Hsieh PC,Liao MC,Shin SJ

更新日期：2012-01-01 00:00:00

abstract：:The untransformed stable cell line Met murine hepatocytes (MMH), generated from liver explants of transgenic mice expressing a constitutively active truncated form of the human hepatocyte growth factor receptor (cyto-Met), represents an innovative tool for in vitro studies of liver function. In the present report, we ...

journal_title：Journal of cellular physiology

authors： Bellovino D,Lanyau Y,Garaguso I,Amicone L,Cavallari C,Tripodi M,Gaetani S

更新日期：1999-10-01 00:00:00

abstract：:Cultured bovine aortic endothelial cells were fixed and stained with NBD-phallicidin and quantitated with a digital image analyzer for changes in actin cables and surface area. Serotonin (5-HT), norepinephrine (NE), dopamine and histamine (all at 10(-4)M concentrations) were tested for their ability to induce cytoskel...

journal_title：Journal of cellular physiology

authors： Welles SL,Shepro D,Hechtman HB

更新日期：1985-06-01 00:00:00

abstract：:We observed previously that each of seven cancer progression inhibitors suppresses the mRNA expression of some matrix metalloproteinases (MMPs), but stimulates that of others, in breast cancer cells. In the present study we tested the effect of overexpressing other cancer modulators on MMP expression. The MMPs tested ...

journal_title：Journal of cellular physiology

authors： Delassus GS,Cho H,Eliceiri GL

更新日期：2011-12-01 00:00:00

abstract：:The methylation of DNA is an epigenetic modification that can play an important role in the control of gene expression in mammalian cells. The enzyme involved in this process is DNA methyltransferase, which catalyzes the transfer of a methyl group from S-adenosyl-methionine to cytosine residues to form 5-methylcytosin...

journal_title：Journal of cellular physiology

authors： Momparler RL,Bovenzi V

更新日期：2000-05-01 00:00:00

abstract：:Current osteoinductive protein therapy utilizes bolus administration of large doses of bone morphogenetic proteins (BMPs), which is costly, and may not replicate normal bone healing. The limited in vivo biologic activity of BMPs requires the investigation of growth factors that may enhance this activity. In this study...

journal_title：Journal of cellular physiology

authors： Arosarena OA,Del Carpio-Cano FE,Dela Cadena RA,Rico MC,Nwodim E,Safadi FF

更新日期：2011-11-01 00:00:00

abstract：:Reactivation of dormant chick erythrocyte (CE) nuclei was studied by fusing chick red cells with rat myoblasts, HeLa cells, and chick fibroblasts. Heterokaryons representing different stages of nuclear reactivation were fixed and examined for nuclear antigens using polyclonal patient autoantisera reacting with mammali...

journal_title：Journal of cellular physiology

authors： Nyman U,Lanfranchi G,Bergman M,Ringertz NR

更新日期：1984-08-01 00:00:00

abstract：:Cellular growth has been found to be directly related to the amount of sodium pumping activity in mouse lymphoblasts (L5178-Y) cultured in varying concentrations of the cardiac glycoside, ouabain. No short-term adaptation (within one generation) occured; i.e., neither growth rate nor (Na+ + K+)-ATPase activity increas...

journal_title：Journal of cellular physiology

authors： Shank BB,Smith NE

更新日期：1976-03-01 00:00:00

abstract：:Bcl-2 associated athanogene 5 (Bag5) is a novel endoplasmic reticulum (ER) regulator. However, its role in catecholamine-induced endothelial cells damage has not been fully understood. In our study, catecholamine was used to mimic hypertension-related endothelial cell damage. Then, western blots, enzyme-linked immunos...

journal_title：Journal of cellular physiology

authors： Zhu H,Zhao M,Chen Y,Li D

更新日期：2021-02-01 00:00:00

abstract：:The progression of T-lymphoma cells (CCRF-CEM) growing in suspension has been monitored during long term (12-28 h) batch experiments using microcalorimetry. In parallel with the calorimetric measurements, changes in cell concentration, pH, p(O2) and concentrations of the main energy sources (glucose and glutamine) wer...

journal_title：Journal of cellular physiology

authors： Bäckman P,Kimura T,Schön A,Wadsö I

更新日期：1992-01-01 00:00:00

abstract：:High potassium concentrations altered the morphology and the ability to grow in soft agar in 6m2 cells, a clone of rat kidney cells infected with a temperature-sensitive mutant of Moloney sarcoma virus. Approximately 60% of cells exhibited normal morphology in the presence of 94.8 mM potassium in isotonic medium at th...

journal_title：Journal of cellular physiology

authors： Lai CN,Becker FF

更新日期：1985-11-01 00:00:00

abstract：:Stimulation of postconfluent Swiss 3T3 cells in serum-free medium with 4.3 mM Ca2+ results in marked increases in both released and cell-associated plasminogen activator (PA). Increased release of PA commenced approximately 10 to 12 hours post-stimulation and continued to increase steadily until 48 hours at which time...

journal_title：Journal of cellular physiology

authors： Chou IN,Cox R,Black PH

更新日期：1979-09-01 00:00:00

abstract：:Breast cancer is a common cancer leading to many deaths among females. Cyclooxygenase-2 (COX-2) and interleukin-8 (IL-8) are two highly expressed inflammatory mediators to be induced by the protein kinase C (PKC) signaling via various inflammatory stimuli and both contribute significantly to cancer metastasis/progress...

journal_title：Journal of cellular physiology

authors： Chou WY,Chuang KH,Sun D,Lee YH,Kao PH,Lin YY,Wang HW,Wu YL

更新日期：2015-09-01 00:00:00

abstract：:Heparin-binding epidermal growth factor-like growth factor (HB-EGF) mRNA and protein expression is induced by EGF in MCF-10A nontransformed and Ha-ras transfected human mammary epithelial cells. The anti-EGF receptor (EGFR) blocking monoclonal antibody (MAb) 225 and the EGFR tyrosine kinase inhibitor PD153035 were abl...

journal_title：Journal of cellular physiology

authors： Martínez-Lacaci I,De Santis M,Kannan S,Bianco C,Kim N,Wallace-Jones B,Wechselberger C,Ebert AD,Salomon DS

更新日期：2001-02-01 00:00:00

abstract：:Stimulation of amiloride-sensitive sodium (Na+) influx and the subsequent activation of NA+, K+-ATPase by serum or growth factors have been implicated as early events leading to initiation of cell proliferation. We recently demonstrated that amiloride inhibits thrombin-initiated DNA synthesis not by inhibiting an earl...

journal_title：Journal of cellular physiology

authors： Stiernberg J,Carney DH,Fenton JW 2nd,LaBelle EF

更新日期：1984-09-01 00:00:00

abstract：:Glioblastoma (GB) is the most common cancer in the brain and with an increasing incidence. Despite major advances in the field, there is no curative therapy for GB to date. Many solid tumors, including GB, experienced metabolic reprogramming in order to sustain uncontrolled proliferation, hypoxic conditions, and angio...

journal_title：Journal of cellular physiology

authors： Benedetti E,d'Angelo M,Ammazzalorso A,Gravina GL,Laezza C,Antonosante A,Panella G,Cinque B,Cristiano L,Dhez AC,Astarita C,Galzio R,Cifone MG,Ippoliti R,Amoroso R,Di Cesare E,Giordano A,Cimini A

更新日期：2017-06-01 00:00:00