Abstract:
:Interleukin-6 (IL-6) contributes to a multitude of physiological and pathophysiological processes. We sought to determine the level of the IL-6 in serum and tumoral tissue of patients with staging of the tumor and whether serum IL-6 level in patients with colorectal cancer correlate with tumoral tissue level of it. Serum and tumoral tissue specimen (stored at -80 degrees C until the biochemical determination) from colorectal cancer (n=50) were examined for IL-6.we determined the IL-6 Level in serum and tumoral tissue supernatant with Instant ELISA kit. A significant association between serum IL-6 level and staging of the tumor (P<0.001), tumoral tissue IL-6 level (r=0.95, P<0.001) in the patients was founded. IL-6 amount of the serum and tumoral tissue in the patients with colorectal cancer correlate significantly with the staging of the tumor and with each other.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Esfandi F,Mohammadzadeh Ghobadloo S,Basati Gdoi
10.1016/j.canlet.2005.12.003keywords:
subject
Has Abstractpub_date
2006-11-28 00:00:00pages
76-8issue
1eissn
0304-3835issn
1872-7980pii
S0304-3835(05)01052-9journal_volume
244pub_type
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