Enhanced Production of Surfactin from Bacillus subtilis by Continuous Product Removal and Metal Cation Additions.

Abstract:

:The lipopeptide, surfactin, is produced by Bacillus subtilis. A study has been made on large-scale production of this surfactant. A good yield was obtained from a glucose substrate fermentation by continuously removing the product by foam fractionation. The surfactin could be easily recovered from the collapsed foam by acid precipitation. The yield was also improved by the addition of either iron or manganese salts. Hydrocarbon addition to the medium, which normally increases biosurfactant production, completely inhibited surfactin production by B. subtilis.

journal_name

Appl Environ Microbiol

authors

Cooper DG,Macdonald CR,Duff SJ,Kosaric N

doi

10.1128/AEM.42.3.408-412.1981

keywords:

subject

Has Abstract

pub_date

1981-09-01 00:00:00

pages

408-12

issue

3

eissn

0099-2240

issn

1098-5336

journal_volume

42

pub_type

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