Abstract：
:Peyronie's disease is an acquired condition that presents clinically with a palpable induration, a distinct plaque, or a curvature of the erect penis. At times, the erections are painful. Erectile dysfunction (ED) often is associated with Peyronie's disease. The current era of phosphodiesterase therapy for the treatment of ED seems to have increased the number of patients presenting for treatment of Peyronie's disease. During the past decade, significant advances have been made in understanding the pathophysiology of the disease, resulting in numerous nonsurgical therapies proposed for the treatment of Peyronie's disease. These medical treatments can be administered systemically, locally, or intralesionally. Unfortunately, there are few randomized, placebo-controlled trials to evaluate most of these proposed therapies. In evaluating therapies for Peyronie's disease, it must be remembered that the natural disease history includes spontaneous resolution of pain and even a small improvement in penile curvature in some men. This article reviews the natural history, scientific understanding, and nonsurgical treatment options for the mild to moderate Peyronie's deformities. Surgical therapy remains the mainstay of treatment for severe and refractory cases of Peyronie's disease that result in a physical or psychologic dysfunction.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Jack GS,Gonzalez-Cadavid N,Rajfer Jdoi
10.1007/s11934-005-0041-2keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
454-60issue
6eissn
1527-2737issn
1534-6285journal_volume
6pub_type
杂志文章,评审abstract：:The conservative treatment of stress urinary incontinence for women has many facets. Each intervention may have value and patients may benefit from simple, reversible recommendations and techniques versus invasive surgery. Starting with a thorough history, lifestyle modifications may lead to decreased incontinence. De...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0056-8
更新日期：2005-09-01 00:00:00
abstract：:Urinary tract infections (UTI) remain one of the most prevalent and frustrating morbidities for neurogenic bladder patients, and death attributed to urosepsis in the spinal cord injury (SCI) patient is higher when compared to the general population. Risk factors include urinary stasis, high bladder pressures, bladder ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0433-2
更新日期：2014-09-01 00:00:00
abstract：:Bladder outlet obstruction (BOO) in women can be either anatomic or functional. Anatomic causes for BOO are often readily apparent by history and physical exam. On the other hand, causes for functional obstruction, including dysfunctional voiding, primary bladder neck obstruction, and detrusor-external sphincter dyssy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0267-8
更新日期：2012-10-01 00:00:00
abstract：:Small renal masses (SRMs; < 4 cm in diameter) account for most renal tumors treated today. Incidental early detection of SRMs by abdominal imaging results in favorable grade and stage migration to renal cell carcinoma, and also increases detection of benign renal tumors. As a result, most SRMs manifest indolent biolog...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0006-3
更新日期：2008-01-01 00:00:00
abstract：:Patients with one or more low-grade bladder tumors of the urinary bladder will often develop a subsequent tumor but these so called "recurrences" are almost always of similar grade and rarely invade beyond the basement membrane. Therefore, the clinician should try to minimize the morbidity associated with treating the...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0555-1
更新日期：2015-12-01 00:00:00
abstract：:In recent years, more attention has turned to the use of patient-reported outcomes in clinical trials to assess treatment efficacy in overactive bladder syndrome (OAB). The challenge for investigators and clinicians is how to choose among the many available health-related quality-of-life questionnaires. This article p...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0064-6
更新日期：2008-09-01 00:00:00
abstract：:The benefit that patients with overactive bladder (OAB) experience with conservative management is an important aspect in the evaluation of this therapy. The first-line options include behavioral interventions, and several techniques are available. Clinical research indicates amelioration of individual symptoms with t...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-012-0262-0
更新日期：2012-10-01 00:00:00
abstract：PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0709-4
更新日期：2017-08-01 00:00:00
abstract：:Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities dir...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0039-4
更新日期：2006-01-01 00:00:00
abstract：:Despite the proven efficacy of oral therapy for erectile dysfunction (ED), some patients are unable to take these medications because of drug interactions (ie, sildenafil and nitroglycerin) or a lack of response. Topical agents represent another minimally invasive option for the treatment of ED. This review discusses ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0100-x
更新日期：2002-12-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0596-0
更新日期：2016-05-01 00:00:00
abstract：:Erectile dysfunction (ED) often is caused by endothelial dysfunction and may be a sign that a patient has vascular disease elsewhere in the body. Risk factors for coronary artery disease such as lipid abnormalities, smoking, diabetes, and hypertension also are risk factors for ED. Oral therapy for ED, such as sildenaf...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-003-0028-9
更新日期：2003-12-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is the most common urologic affliction in aging men, leading to adverse clinical outcomes in a significant proportion of the population. Serum prostate-specific antigen (PSA) has been established as a marker for prostate cancer for the past two decades but more recently has been reco...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0072-y
更新日期：2007-07-01 00:00:00
abstract：:The presence of a sufficient amount of androgens is essential for adequate sexual function in men. Gonadal hormones profoundly affect cognitive functions and, therefore, are fundamental in maintaining sexual desire. The earliest manifestation of hypogonadism is diminished libido. Furthermore, androgens also act periph...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0202-4
更新日期：2011-12-01 00:00:00
abstract：:Overactive bladder (OAB) affects millions of people in the United States, and as the population ages, the prevalence of OAB will invariably increase. Conventional therapy for OAB includes behavioral modification and anticholinergic medication. OAB treatment comes with significant economic impact. With anticholinergic ...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0054-3
更新日期：2009-09-01 00:00:00
abstract：PURPOSE OF REVIEW:From health systems to individuals, nephrolithiasis is economically burdensome. The aim of the current paper is to characterize the financial burden of disease associated with nephrolithiasis with an emphasis on investigating treatment modality economic efficiency. RECENT FINDINGS:For small volume pr...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-00971-6
更新日期：2020-03-31 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this paper is to describe the pathophysiology of adult nocturnal enuresis and develop a generalized approach for evaluation and treatment. RECENT FINDINGS:Although nocturnal enuresis (NE) impacts a significant proportion of the adult population, research on this topic remains lacking. In ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-00983-2
更新日期：2020-06-06 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of the study is to review and summarize major additions to the literature as pertains to enhanced recovery protocols after radical cystectomy in the past year. RECENT FINDINGS:Enhanced recovery after surgery protocols is multimodal pathways that include elements to optimize all stages of ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0855-3
更新日期：2018-10-18 00:00:00
abstract：:Correct staging of prostate cancer at initial diagnosis, as well as accurate staging and tumor localization with biochemical recurrence, remains generally inaccurate with current imaging techniques. Newer modalities are being investigated to accurately identify patients with prostate cancer at different stages of dise...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0018-9
更新日期：2006-05-01 00:00:00
abstract：PURPOSE OF REVIEW:This review provides a critical literature overview of the risks and benefits of transplantectomy in patients with a failed allograft. Additionally, it offers a summary of related problems, primarily alloantibody sensitization in the event of nephrectomy and immunosuppression weaning. RECENT FINDINGS...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-020-0957-6
更新日期：2020-01-18 00:00:00
abstract：PURPOSE OF REVIEW:Bladder cancer care is costly due to long surveillance periods for non-muscle-invasive bladder cancer (NMIBC) and comorbidities associated with the surgical treatment of muscle-invasive bladder cancer (MIBC). We reviewed current evidence-based practices and propose quality metrics for NMIBC and MIBC. ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0856-2
更新日期：2018-10-24 00:00:00
abstract：:Numerous surgeries have been proposed for the treatment of genuine stress incontinence, with the goals to improve functional outcome and decrease complications and their associated morbidity. Two new, minimally invasive procedures, transvaginal retropubic urethropexy and transvaginal Cooper's ligament sling, are revie...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-996-0018-9
更新日期：2001-10-01 00:00:00
abstract：PURPOSE OF REVIEW:Male urethral stricture disease is characterized by the formation of scar tissue within the urethra resulting in lower urinary tract symptoms, infection, and potentially kidney dysfunction. There is significant variability in clinical practice for the treatment of urethral stricture. We sought to summ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0771-6
更新日期：2018-02-26 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0024-6
更新日期：2007-01-01 00:00:00
abstract：PURPOSE OF THE REVIEW:There is an abundance of evidence that the human microbiome plays an important and nuanced role in controlling human metabolism, immunity, and cancer. Herein we aim to review the most current research looking at prostate cancer and its link with the gut and genitourinary microbiome. There is now a...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0922-4
更新日期：2019-09-07 00:00:00
abstract：:Global improvements in water quality, management of infectious diseases, and other medical therapeutics have resulted in a growing population of healthy aging men. One obligate anatomic consequence of aging for these men is the development of benign prostatic hyperplasia (BPH) with secondary bladder outlet obstruction...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0403-8
更新日期：2014-05-01 00:00:00
abstract：:Focal therapy for prostate cancer has emerged an interesting concept as a less morbid option for the treatment of localized low-risk disease. Despite the growing interest in focal therapy, this approach has not yet gained sufficient popularity nor provided enough data to be discussed outside the experimental applicati...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0100-1
更新日期：2010-05-01 00:00:00
abstract：:Patients diagnosed with prostate cancer who elect to pursue active treatment of their disease must choose among the many available treatment alternatives. Several treatment options now exist for similar-stage disease (clinical T1-3N0M0), including radical prostatectomy, external beam radiation, prostate brachytherapy ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-000-0034-0
更新日期：2000-05-01 00:00:00
abstract：:Nodal staging in prostate cancer is suboptimal both with respect to current imaging modalities and pelvic lymph node dissection, and thus other techniques are being explored. Lymphotropic nanoparticle-enhanced MRI, also called magnetic resonance lymphography (MRL), is a technique that has shown high sensitivity (65-92...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0389-7
更新日期：2014-03-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischem...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-013-0363-4
更新日期：2013-12-01 00:00:00
