Abstract：
:Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities directly linked to prostate cancer, most men harboring the disease will die of other causes. This fact poses substantial dilemmas for screening programs designed to diagnose cancers at an early stage, as the optimal approach also would provide guidance as to which cancers could or should be observed, versus those malignancies that require curative therapy, and whether localized treatments are sufficient or if additional systemic interventions are indicated. To address these issues, substantial resources have been focused on the identification of biomarkers capable of specifically and sensitively diagnosing prostate cancers and providing prognostic information. However, the discovery and use of biomarkers must contend with the complexity and heterogeneity of body fluids and tissues. This review describes approaches that use cell type-specific analysis methods to identify cancer-associated features with the potential of distinguishing individuals with cancer of the prostate.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Nelson PS,Montgomery Bdoi
10.1007/s11934-006-0039-4keywords:
subject
Has Abstractpub_date
2006-01-01 00:00:00pages
57-63issue
1eissn
1527-2737issn
1534-6285journal_volume
7pub_type
杂志文章,评审abstract：:The lack of reliable imaging tools in detecting prostate cancer makes a random biopsy still the standard of care to detect prostate cancer. To reduce the number of cores during a biopsy and therefore the risk of biopsy-related complications, an imaging tool which provides reliable guided biopsies is required. Transrec...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0392-z
更新日期：2014-03-01 00:00:00
abstract：:Overactive bladder syndrome continues to be a significant burden for the general population. Current first-line medical therapy often includes antimuscarinic medications designed for overactive bladder. Poor efficacy and significant side effects of these antimuscarinic medications have left patients and physicians loo...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0134-4
更新日期：2010-09-01 00:00:00
abstract：:The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0445-y
更新日期：2014-10-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0911-7
更新日期：2019-06-15 00:00:00
abstract：PURPOSE OF REVIEW:Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to adva...
journal_title：Current urology reports
pub_type： 历史文章,杂志文章,评审
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更新日期：2019-01-30 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-003-0028-9
更新日期：2003-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Intratumor heterogeneity is an inherent event in tumor development that is receiving much attention in the last years since it is responsible for most failures of current targeted therapies. The purpose of this review is to offer clinicians an updated insight of the multiple manifestations of a comple...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0754-7
更新日期：2018-01-27 00:00:00
abstract：:Bladder outlet obstruction (BOO) in women can be either anatomic or functional. Anatomic causes for BOO are often readily apparent by history and physical exam. On the other hand, causes for functional obstruction, including dysfunctional voiding, primary bladder neck obstruction, and detrusor-external sphincter dyssy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0267-8
更新日期：2012-10-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0066-8
更新日期：2002-06-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-996-0018-9
更新日期：2001-10-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0054-0
更新日期：2007-11-01 00:00:00
abstract：:Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent disease for which there is no standardized therapy. Traditional treatments have included antibiotics, α-blockers, and anti-inflammatories, but those have not proven to be efficacious therapies through many clinical trials. Alternative therapies,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0188-y
更新日期：2011-08-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0856-2
更新日期：2018-10-24 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0505-y
更新日期：2015-05-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0792-1
更新日期：2018-04-17 00:00:00
abstract：PURPOSE OF REVIEW:The symptoms of lower urinary tract dysfunction (LUTD) including urinary incontinence, frequency, and urgency are among the most common reasons children are referred to pediatric urologists. Despite this, the workup for LUTD is often time consuming and a source of frustration for patients, parents, an...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0784-1
更新日期：2018-04-06 00:00:00
abstract：PURPOSE OF REVIEW:Spina bifida is caused by incomplete neural tube closure during the first trimester. This condition may lead to bowel and bladder dysfunction as well as truncal weakness and motor anomalies. Presentations vary between myelomeningoceles and lipomeningoceles and may result in different outcomes. This re...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0684-9
更新日期：2017-05-01 00:00:00
abstract：:The most important change in urology during the past decade was the development of minimally invasive surgery, particularly laparoscopy. However, the main drawback of laparoscopy is a steep learning curve, which results from the significant changes in the surgical environment. Although laparoscopy can provide importan...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-003-0040-0
更新日期：2003-04-01 00:00:00
abstract：PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0709-4
更新日期：2017-08-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0030-z
更新日期：2001-02-01 00:00:00
abstract：:The Infectious Diseases Society of America has published guidelines for the treatment of uncomplicated cystitis. Recommendations are that for healthy, adult, nonpregnant women with bacterial cystitis, 3 days of trimethoprim/ sulfamethoxazole (TMP/SMZ) or trimethoprim alone is standard therapy in those regions where le...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0072-2
更新日期：2001-08-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-000-0034-0
更新日期：2000-05-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0236-2
更新日期：2012-04-01 00:00:00
abstract：:The use of injectable bulking agents into the submucosal layer of the pediatric urinary tract continues to grow. Treatment strategies for vesicoureteral reflux and urinary incontinence have changed with the introduction of dextranomer/hyaluronic acid as a minimally invasive option. Socially and medically debilitating ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0074-1
更新日期：2006-03-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0080-8
更新日期：2005-03-01 00:00:00
abstract：:Most children born with spina bifida, the most common disabling congenital abnormality, have normal renal function. If left untreated, more than half of these children will have serious renal deterioration by age 5. This deterioration is secondary to hostile neurogenic changes of the bladder. Renal development should ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0027-y
更新日期：2008-03-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischem...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-013-0363-4
更新日期：2013-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Urethral strictures that are refractory to initial management present unique challenges to the reconstructive surgeon. Treatment trends have shifted as new tissue resources are becoming available. There is renewed interest in old methods as skill and technique have improved. We describe the scope of t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
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更新日期：2018-02-26 00:00:00
abstract：PURPOSE OF REVIEW:In light of the announcement that the United States Medical Licensing Examination Step 1 exam will transition to pass/fail reporting, we reviewed recent literature on evaluating residency applicants with a focus on identifying objective measurements of applicant potential. RECENT FINDINGS:References ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-00993-0
更新日期：2020-08-17 00:00:00
abstract：:Because the number of patients requiring oral anticoagulation (OA) is steadily growing, more and more patients requiring surgical treatment of benign prostatic hyperplasia (BPH) are on OA. Laser treatment of BPH was said to offer a higher quality of hemostasis than transurethral resection of the prostate (TURP). Thus,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0115-7
更新日期：2010-07-01 00:00:00
