Abstract：
PURPOSE OF REVIEW:The classification of morphologically normal sperm has been progressively redefined. Concurrently, our understanding of the significance of sperm morphology in relation to male factor infertility has evolved. In this review, we will discuss the evolution of sperm morphology assessment and factors that contribute to its measurement variability. We will examine the impact of sperm morphology on natural pregnancy, IUI, IVF, and ICSI outcomes. RECENT FINDINGS:There is a lack of consensus on sperm morphology classification, technique, and inter-observer grading variability. Current evidence suggests sperm morphology has low predictive value for pregnancy success, for both natural and assisted reproduction. Additionally, the threshold for what is considered an adequate percentage of morphologically normal sperm has changed over time. These variables have called into question the relevance of this variable in predicting fertility outcomes. Our understanding of the impact of sperm morphology on reproductive outcomes continues to evolve and seems to play less of a role than initially thought.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Danis RB,Samplaski MKdoi
10.1007/s11934-019-0911-7subject
Has Abstractpub_date
2019-06-15 00:00:00pages
43issue
8eissn
1527-2737issn
1534-6285pii
10.1007/s11934-019-0911-7journal_volume
20pub_type
杂志文章,评审abstract：:Laparoscopic surgery was originally developed by gynecologists and general surgeons. Based on their experience, the first successful laparoscopic procedures in urology were performed transperitoneally. However, this novel technique transformed traditionally retroperitoneal procedures into transperitoneal procedures, g...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0020-z
更新日期：2004-04-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischem...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-013-0363-4
更新日期：2013-12-01 00:00:00
abstract：:Bulking therapy for stress urinary incontinence in women continues to evolve from the standpoint of material science. Several new materials have recently been subjected to clinical trials with the aim of assessing efficacy and safety of these agents for possible device registration. These new additions run the gamut o...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0012-2
更新日期：2006-09-01 00:00:00
abstract：:Each of the three most common contemporary treatments for localized prostate cancer, radical prostatectomy, external beam radiotherapy, and brachytherapy, can have adverse effects on sexual health. Sexual health outcome can be improved by treatment-specific factors, such as the use of nerve-sparing technique during ra...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0039-1
更新日期：2004-06-01 00:00:00
abstract：:Surgical treatment of long urethral stricture disease remains one of the most challenging problems in urology. In recent years there has been continuous discussion with regard to the etiology, location, length, and management of extensive urethral stricture disease. Various tissues such as genital and extragenital ski...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0424-3
更新日期：2014-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Targeting PD-1/PD-L1 immune checkpoints is a new therapeutic tool in patients with locally advanced and metastatic clear cell renal cell carcinoma (CCRCC). The purpose of this review is to offer clinicians an updated translational insight into the current status of a therapeutic alternative that may i...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0866-8
更新日期：2019-01-15 00:00:00
abstract：PURPOSE OF REVIEW:The symptoms of lower urinary tract dysfunction (LUTD) including urinary incontinence, frequency, and urgency are among the most common reasons children are referred to pediatric urologists. Despite this, the workup for LUTD is often time consuming and a source of frustration for patients, parents, an...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0784-1
更新日期：2018-04-06 00:00:00
abstract：PURPOSE OF REVIEW:Intratumor heterogeneity is an inherent event in tumor development that is receiving much attention in the last years since it is responsible for most failures of current targeted therapies. The purpose of this review is to offer clinicians an updated insight of the multiple manifestations of a comple...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0754-7
更新日期：2018-01-27 00:00:00
abstract：PURPOSE OF REVIEW:Spina bifida is caused by incomplete neural tube closure during the first trimester. This condition may lead to bowel and bladder dysfunction as well as truncal weakness and motor anomalies. Presentations vary between myelomeningoceles and lipomeningoceles and may result in different outcomes. This re...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0684-9
更新日期：2017-05-01 00:00:00
abstract：PURPOSE OF REVIEW:There are an estimated 33 million men and women with overactive bladder (OAB) in the USA. Despite the prevalence of OAB, it remains a frequently misdiagnosed condition. OAB has shared symptomatology with other common urologic conditions, namely recurrent urinary tract infections (UTIs). Here, we will ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0839-3
更新日期：2018-09-13 00:00:00
abstract：:Correct staging of prostate cancer at initial diagnosis, as well as accurate staging and tumor localization with biochemical recurrence, remains generally inaccurate with current imaging techniques. Newer modalities are being investigated to accurately identify patients with prostate cancer at different stages of dise...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0018-9
更新日期：2006-05-01 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this paper is to describe the pathophysiology of adult nocturnal enuresis and develop a generalized approach for evaluation and treatment. RECENT FINDINGS:Although nocturnal enuresis (NE) impacts a significant proportion of the adult population, research on this topic remains lacking. In ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-00983-2
更新日期：2020-06-06 00:00:00
abstract：:Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0030-z
更新日期：2001-02-01 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this chapter is to review the recent epidemiologic trends of kidney stone disease and discuss the impact of the increasing incidence of nephrolithiasis among children on adults with respect to extra-renal manifestations, surgical management, and secondary prevention. RECENT FINDINGS:Among...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0691-x
更新日期：2017-06-01 00:00:00
abstract：:Partial nephrectomy has become an accepted treatment of cT1 renal masses as it provides improved long-term renal function compared to radical nephrectomy (Campbell et al. J Urol. 182:1271-9, 2009). Hilar clamping is utilized to help reduce bleeding and improve visibility during tumor resection. However, concern over r...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0596-0
更新日期：2016-05-01 00:00:00
abstract：:Symptoms such as overactive bladder represent disorders of bladder control. Functional brain scanning by positron emission tomography and functional magnetic resonance imaging suggest that normal control is exerted by a network of regions in the emotional nervous system, including periaqueductal gray, thalamus, insula...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0081-z
更新日期：2004-10-01 00:00:00
abstract：:Pediatric urolithiasis is on the rise globally and incidence rates have risen by 6-10% annually over the past couple of decades. Given the increasing incidence, high likelihood of recurrence, and long life expectancy of children, the use of ionizing radiation in the diagnosis, management, and follow up of pediatric ur...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0669-8
更新日期：2017-03-01 00:00:00
abstract：:Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0212-2
更新日期：2011-12-01 00:00:00
abstract：:Patients with one or more low-grade bladder tumors of the urinary bladder will often develop a subsequent tumor but these so called "recurrences" are almost always of similar grade and rarely invade beyond the basement membrane. Therefore, the clinician should try to minimize the morbidity associated with treating the...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0555-1
更新日期：2015-12-01 00:00:00
abstract：:Laparoscopic adrenalectomy is considered to be the standard of care for the surgical excision of the adrenal gland. Since the initial report of laparoscopic adrenalectomy in 1992, it has evolved into a feasible and reproducible minimally invasive procedure for benign adrenal tumors. Transperitoneal and retroperitoneal...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0070-x
更新日期：2005-02-01 00:00:00
abstract：:Inflatable penile prosthesis (IPP) is an effective treatment for erectile dysfunction in patients' refractory to oral or injectable treatment. While the rate of infection has decreased over the past decade, it is still the most feared complication of IPP placement. Here, we assemble possible patient and surgical facto...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0554-2
更新日期：2015-12-01 00:00:00
abstract：:Focal therapy for prostate cancer has emerged an interesting concept as a less morbid option for the treatment of localized low-risk disease. Despite the growing interest in focal therapy, this approach has not yet gained sufficient popularity nor provided enough data to be discussed outside the experimental applicati...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0100-1
更新日期：2010-05-01 00:00:00
abstract：:Androgen deprivation therapy (ADT) is a well-established treatment for locally advanced, biochemically recurrent and metastatic prostate cancer. However, it is associated with significant side effects including hot flashes, loss of libido and erectile function, muscular atrophy, metabolic abnormalities, and osteoporos...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0481-2
更新日期：2015-03-01 00:00:00
abstract：PURPOSE OF REVIEW:Targeted therapy for genitourinary cancer is being used at an increasing rate. These medications show great survival benefit but are relatively lacking in long-term adverse effect data. With increasing survivability, measures to improve quality of life must be considered for GU cancer and a large prop...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0704-9
更新日期：2017-08-01 00:00:00
abstract：PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0709-4
更新日期：2017-08-01 00:00:00
abstract：:Recent studies have cast doubt on the reliability of serum total prostate-specific antigen as a biomarker for the detection and prognosis of prostate cancer. Biomarkers that can identify those men at risk for clinically significant prostate cancer are desperately needed. The search for biomarkers that may improve the ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0004-7
更新日期：2005-05-01 00:00:00
abstract：:DNA microarray technology provides a means to examine large numbers of molecular changes related to a biological process in a high throughput manner. This review discusses plausible utilities of this technology in prostate cancer research, including definition of prostate cancer predisposition, global profiling of gen...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0011-x
更新日期：2002-02-01 00:00:00
abstract：:Global improvements in water quality, management of infectious diseases, and other medical therapeutics have resulted in a growing population of healthy aging men. One obligate anatomic consequence of aging for these men is the development of benign prostatic hyperplasia (BPH) with secondary bladder outlet obstruction...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0403-8
更新日期：2014-05-01 00:00:00
abstract：:Complications of locally advanced prostate cancer are often overlooked in the overall treatment of prostate cancer, can have significant morbidity, and can provide a challenge for the treating urologist. Despite advances in early detection and treatment of prostate cancer, as many as 10% of patients present with or de...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0008-6
更新日期：2007-05-01 00:00:00
abstract：:The management of clinical benign prostatic hyperplasia (BPH) remains a common problem in daily urologic practice. Recently, a new minimally invasive procedure for BPH, the Urolift System, has been introduced. This article reviews the current literature discussing the technique, efficacy, adverse events, limitations, ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0619-x
更新日期：2016-09-01 00:00:00
